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    Also known as: 66592-87-8, Duricef, Cefadroxil hydrate, Bidocel, Cefadroxil 1-wasser, Duracef
    Molecular Formula
    C16H19N3O6S
    Molecular Weight
    381.4  g/mol
    InChI Key
    NBFNMSULHIODTC-CYJZLJNKSA-N
    FDA UNII
    280111G160
    Cefadroxil Monohydrate
    Long-acting, broad-spectrum, water-soluble, CEPHALEXIN derivative.
    1 2D Structure

    Cefadroxil Monohydrate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
    2.1.2 InChI
    InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1
    2.1.3 InChI Key
    NBFNMSULHIODTC-CYJZLJNKSA-N
    2.1.4 Canonical SMILES
    CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O.O
    2.1.5 Isomeric SMILES
    CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O.O
    2.2 Other Identifiers
    2.2.1 UNII
    280111G160
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4 Hydroxycephalexin

    2. 4-hydroxycephalexin

    3. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, (6r-(6alpha,7beta(r*)))-

    4. Bidocef

    5. Bl S 578

    6. Bl S578

    7. Bl-s 578

    8. Bl-s578

    9. Bls 578

    10. Bls578

    11. Cefadroxil

    12. Cefadroxil Anhydrous

    13. Cephadroxyl

    14. Duricef

    15. S 578

    16. S-578

    17. S578

    18. Ultracef

    2.3.2 Depositor-Supplied Synonyms

    1. 66592-87-8

    2. Duricef

    3. Cefadroxil Hydrate

    4. Bidocel

    5. Cefadroxil 1-wasser

    6. Duracef

    7. Mjf 11567-3

    8. Bl-s578

    9. Cefadroxil (hydrate)

    10. (6r,7r)-7-((r)-2-amino-2-(p-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid Monohydrate

    11. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2r)-amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, Monohydrate, (6r,7r)-

    12. 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid,7-[[(2r)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,monohydrate, (6r,7r)-

    13. Ultracef

    14. Moxacef Kapseln

    15. Baxan Kapseln

    16. Cefos Granulat

    17. Kefroxil Kapseln

    18. Omnidrox Kapseln

    19. Mjf-11567-3

    20. 280111g160

    21. Cefadroxil (as Monohydrate)

    22. (6r,7r)-7-((r)-2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Hydrate

    23. (6r,7r)-7-[[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid;hydrate

    24. Cefadroxil (usp)

    25. Duricef (tn)

    26. Unii-280111g160

    27. Cefadroxil [usan:usp:inn:ban:jan]

    28. (6r,7r)-7-[[(2r)-2-azaniumyl-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    29. Cefadroxil [usan]

    30. Cefadroxil [vandf]

    31. Cefadroxil [usp-rs]

    32. Schembl33620

    33. Cefadroxil [green Book]

    34. Chebi:53667

    35. Hy-b1190a

    36. Dtxsid80904597

    37. Cefadroxil [usp Monograph]

    38. Cefadroxil Monohydrate [mi]

    39. S3636

    40. Cefadroxil Monohydrate [vandf]

    41. Akos015896360

    42. Ccg-268421

    43. Cefadroxil Monohydrate [who-dd]

    44. Nsc 756664

    45. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, Monohydrate, (6r-(6alpha,7beta(r*)))-

    46. As-75209

    47. Cefadroxil Monohydrate [ep Monograph]

    48. Cs-0014294

    49. D02353

    50. D95152

    51. Q27124149

    52. (6r,7r)-7-((r)-2-amino-2-(4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacidhydrate

    53. (6r,7r)-7-[(2r)-2-amino-2-(4-hydroxyphenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Hydrate

    54. (6r,7r)-7-{[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid--water (1/1)

    55. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-, Monohydrate, (6r-(6.alpha.,7.beta.(r*)))

    56. 7beta-{[(2r)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,4-didehydrocepham-4-carboxylic Acid--water (1/1)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 381.4 g/mol
    Molecular Formula C16H19N3O6S
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count4
    Exact Mass381.09945651 g/mol
    Monoisotopic Mass381.09945651 g/mol
    Topological Polar Surface Area159 Ų
    Heavy Atom Count26
    Formal Charge0
    Complexity629
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    API Reference Price

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    07-Jan-2021
    28-Oct-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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