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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: Cephalonium, 5575-21-3, Nsc-759292, Cefalonum, Cefalonium hydrate, K2p920217w
Molecular Formula
C20H18N4O5S2
Molecular Weight
458.5  g/mol
InChI Key
FMZXNVLFJHCSAF-DNVCBOLYSA-N
FDA UNII
K2P920217W

Cefalonium
Cefalonium is a first-generation semi-synthetic cephalosporin antibiotic with activity against aerobic gram-positive and some community-acquired gram-negative bacteria. Cefalonium is used in veterinary medicine.
1 2D Structure

Cefalonium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2.1.2 InChI
InChI=1S/C20H18N4O5S2/c21-17(26)11-3-5-23(6-4-11)9-12-10-31-19-15(18(27)24(19)16(12)20(28)29)22-14(25)8-13-2-1-7-30-13/h1-7,15,19H,8-10H2,(H3-,21,22,25,26,28,29)/t15-,19-/m1/s1
2.1.3 InChI Key
FMZXNVLFJHCSAF-DNVCBOLYSA-N
2.1.4 Canonical SMILES
C1C(=C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N
2.1.5 Isomeric SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CS3)C(=O)[O-])C[N+]4=CC=C(C=C4)C(=O)N
2.2 Other Identifiers
2.2.1 UNII
K2P920217W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cephalonium

2. Cepravin D.c.

3. Cepravin Dry Cow

2.3.2 Depositor-Supplied Synonyms

1. Cephalonium

2. 5575-21-3

3. Nsc-759292

4. Cefalonum

5. Cefalonium Hydrate

6. K2p920217w

7. (6r,7r)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

8. Dsstox_cid_25388

9. Dsstox_rid_80845

10. Dsstox_gsid_45388

11. Cefalonium [inn]

12. Cefalonio

13. Cefalonium [inn-latin]

14. Cefalonio [inn-spanish]

15. Lilly 41071

16. (6r,7r)-3-((4-carbamoylpyridin-1-ium-1-yl)methyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

17. Cefalonium [inn:ban]

18. Einecs 226-948-7

19. Brn 4169337

20. Unii-k2p920217w

21. Ncgc00016657-01

22. Cefalonium (ban)

23. Cas-5575-21-3

24. Cepravin Dry Cow (tn)

25. Cefalonium [jan]

26. Cephalonium [mi]

27. Cefalonium [mart.]

28. 7-(alpha-thienylacetamido)-3-(4-carbamoylpyridinomethyl)-3-cephem-4-carboxylic Acid

29. (6r,7r)-3-(4-(4-carbamoyl-1-pyridiniomethyl)-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylat

30. 3-(4-carbamoylpyridylmethyl)-8-oxo-7-(alpha-(thien-2-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2carbonsaeure

31. Schembl125252

32. Cephalonium [green Book]

33. Chembl2105567

34. Dtxsid5045388

35. Chebi:95345

36. Hms1571g13

37. Hms2098g13

38. Pharmakon1600-01505997

39. Methyl3-isocyano-3-phenylpropionate

40. Tox21_110548

41. Nsc759292

42. Akos026749802

43. Tox21_110548_1

44. Ccg-213999

45. Db11385

46. Nsc 759292

47. Ncgc00179310-01

48. Ncgc00179310-03

49. Pyridinium, 4-carbamoyl-1-((2-carboxy-8-oxo-7-(2-(2-thienyl)acetamido)-5-thia-1-aza-bicyclo(4.2.0)oct-2-en-3-yl)methyl)- Hydroxide, Inner Salt

50. Ab00513991

51. D07634

52. Ab00513991_02

53. A830789

54. Q5057218

55. 3-(4-carbamoylpyridylmethyl)-8-oxo-7-(a-(thien-2-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid

56. 3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 458.5 g/mol
Molecular Formula C20H18N4O5S2
XLogP30.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass458.07186203 g/mol
Monoisotopic Mass458.07186203 g/mol
Topological Polar Surface Area190 Ų
Heavy Atom Count31
Formal Charge0
Complexity806
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Cefalonium Manufacturers

A Cefalonium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cefalonium, including repackagers and relabelers. The FDA regulates Cefalonium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cefalonium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cefalonium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cefalonium Suppliers

A Cefalonium supplier is an individual or a company that provides Cefalonium active pharmaceutical ingredient (API) or Cefalonium finished formulations upon request. The Cefalonium suppliers may include Cefalonium API manufacturers, exporters, distributors and traders.

click here to find a list of Cefalonium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cefalonium GMP

Cefalonium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cefalonium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cefalonium GMP manufacturer or Cefalonium GMP API supplier for your needs.

Cefalonium CoA

A Cefalonium CoA (Certificate of Analysis) is a formal document that attests to Cefalonium's compliance with Cefalonium specifications and serves as a tool for batch-level quality control.

Cefalonium CoA mostly includes findings from lab analyses of a specific batch. For each Cefalonium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cefalonium may be tested according to a variety of international standards, such as European Pharmacopoeia (Cefalonium EP), Cefalonium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cefalonium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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