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Chemistry

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Also known as: 61270-78-8, Monocid, Cefonicid disodium salt, Sk&f d-75073-z2, Cefonicide sodium, Cefonicid (sodium)
Molecular Formula
C18H16N6Na2O8S3
Molecular Weight
586.5  g/mol
InChI Key
NAXFZVGOZUWLEP-RFXDPDBWSA-L
FDA UNII
F74MFL78A1

CEFONICID SODIUM
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
1 2D Structure

CEFONICID SODIUM

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;(6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[1-(sulfonatomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2.1.2 InChI
InChI=1S/C18H18N6O8S3.2Na/c25-13(9-4-2-1-3-5-9)14(26)19-11-15(27)24-12(17(28)29)10(6-33-16(11)24)7-34-18-20-21-22-23(18)8-35(30,31)32;;/h1-5,11,13,16,25H,6-8H2,(H,19,26)(H,28,29)(H,30,31,32);;/q;2*+1/p-2/t11-,13-,16-;;/m1../s1
2.1.3 InChI Key
NAXFZVGOZUWLEP-RFXDPDBWSA-L
2.1.4 Canonical SMILES
C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)O)C(=O)[O-])CSC4=NN=NN4CS(=O)(=O)[O-].[Na+].[Na+]
2.1.5 Isomeric SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)O)C(=O)[O-])CSC4=NN=NN4CS(=O)(=O)[O-].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
F74MFL78A1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cefonicid

2. Cefonicid Disodium Salt

3. Cefonicid Monosodium

4. Cefonicid Monosodium Salt

5. Cefonicid, Sodium

6. Monocid

7. Sk And F 75073

8. Sk And F-75073

9. Sk And F75073

10. Skf 75073 2

11. Skf-75073-2

12. Skf750732

13. Sodium Cefonicid

2.3.2 Depositor-Supplied Synonyms

1. 61270-78-8

2. Monocid

3. Cefonicid Disodium Salt

4. Sk&f D-75073-z2

5. Cefonicide Sodium

6. Cefonicid (sodium)

7. Chebi:3492

8. F74mfl78a1

9. Sk&f-d-75073-z2

10. (6r,7r)-7-((r)-mandelamido)-8-oxo-3-(((1-(sulfomethyl)-1-h-tetrazol-5-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, Disodium Salt

11. Disodium;(6r,7r)-7-[[(2r)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[1-(sulfonatomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

12. Monocid Sodium

13. Cefonicid Sodium [usan]

14. Cefonicid Disodium

15. Ncgc00167458-01

16. Skf 75073

17. Unii-f74mfl78a1

18. Cefonicid Sodium [usan:usp]

19. Monocid (tn)

20. Cefonicid Sodium (usp)

21. Dsstox_cid_26642

22. Dsstox_rid_81788

23. Dsstox_gsid_46642

24. Schembl41895

25. 190181-58-9

26. Cefonicid Sodium [vandf]

27. Chembl1201005

28. Dtxsid0046642

29. Cefonicid Sodium [mart.]

30. Cefonicid Sodium [usp-rs]

31. Cefonicid Sodium [who-dd]

32. Tox21_112462

33. Cefonicid Disodium Salt [mi]

34. Mfcd00941437

35. Akos015896359

36. Cefonicid Sodium [orange Book]

37. Ccg-270152

38. Cefonicid Sodium [usp Impurity]

39. Sk&f D-75073-z(sub 2)

40. Sk&f-d-75073-z(sub 2)

41. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1h-tetrazol-5-yl)thio)methyl)disodium Salt, (6r-(6alpha,7beta(r*)))

42. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1h-tetrazol-5-yl)thio)methyl)disodium Salt, (6r-(6alpha,7beta(r*)))-

43. Cas-61270-78-8

44. C08105

45. C75868

46. D00912

47. A833136

48. Q27106106

49. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-(sulfomethyl)-1h-tetrazol-5-yl)thio)methyl)disodium Salt, (6r-(6.alpha.,7.beta.(r*)))-

50. Disodium 7-[(2-hydroxy-2-phenyl-acetyl)amino]-8-oxo-3-[[1-(sulfonatomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

51. Sodium (6r,7r)-7-((r)-2-hydroxy-2-phenylacetamido)-8-oxo-3-(((1-(sulfonatomethyl)-1h-tetrazol-5-yl)thio)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

52. Sodium (6r,7r)-7-((r)-2-hydroxy-2-phenylacetamido)-8-oxo-3-((1-(sulfonatomethyl)-1h-tetrazol-5-ylthio)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

53. Sodium(6r,7r)-7-((r)-2-hydroxy-2-phenylacetamido)-8-oxo-3-(((1-(sulfonatomethyl)-1h-tetrazol-5-yl)thio)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 586.5 g/mol
Molecular Formula C18H16N6Na2O8S3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count13
Rotatable Bond Count7
Exact Mass585.99871357 g/mol
Monoisotopic Mass585.99871357 g/mol
Topological Polar Surface Area270 Ų
Heavy Atom Count37
Formal Charge0
Complexity980
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


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ABOUT THIS PAGE

Cefonicid Disodium Salt Manufacturers

A Cefonicid Disodium Salt manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cefonicid Disodium Salt, including repackagers and relabelers. The FDA regulates Cefonicid Disodium Salt manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cefonicid Disodium Salt API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cefonicid Disodium Salt manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cefonicid Disodium Salt Suppliers

A Cefonicid Disodium Salt supplier is an individual or a company that provides Cefonicid Disodium Salt active pharmaceutical ingredient (API) or Cefonicid Disodium Salt finished formulations upon request. The Cefonicid Disodium Salt suppliers may include Cefonicid Disodium Salt API manufacturers, exporters, distributors and traders.

click here to find a list of Cefonicid Disodium Salt suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cefonicid Disodium Salt GMP

Cefonicid Disodium Salt Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cefonicid Disodium Salt GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cefonicid Disodium Salt GMP manufacturer or Cefonicid Disodium Salt GMP API supplier for your needs.

Cefonicid Disodium Salt CoA

A Cefonicid Disodium Salt CoA (Certificate of Analysis) is a formal document that attests to Cefonicid Disodium Salt's compliance with Cefonicid Disodium Salt specifications and serves as a tool for batch-level quality control.

Cefonicid Disodium Salt CoA mostly includes findings from lab analyses of a specific batch. For each Cefonicid Disodium Salt CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cefonicid Disodium Salt may be tested according to a variety of international standards, such as European Pharmacopoeia (Cefonicid Disodium Salt EP), Cefonicid Disodium Salt JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cefonicid Disodium Salt USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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