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    Chemistry

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    Also known as: 62893-20-3, Sodium cefoperazone, Cefoperazone sodium salt, Cefobid, Tomabef, T-1551
    Molecular Formula
    C25H26N9NaO8S2
    Molecular Weight
    667.7  g/mol
    InChI Key
    NCFTXMQPRQZFMZ-WERGMSTESA-M
    FDA UNII
    5FQG9774WD
    Cefoperazone Sodium
    Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.
    1 2D Structure

    Cefoperazone Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;(6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    2.1.2 InChI
    InChI=1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2;/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41);/q;+1/p-1/t15-,16-,22-;/m1./s1
    2.1.3 InChI Key
    NCFTXMQPRQZFMZ-WERGMSTESA-M
    2.1.4 Canonical SMILES
    CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+]
    2.1.5 Isomeric SMILES
    CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    5FQG9774WD
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cfobis

    2. Cefobid

    3. Cefoperazon

    4. Cefoperazone

    5. Cefoperazone Sodium Salt

    6. Salt, Cefoperazone Sodium

    7. Sodium Salt, Cefoperazone

    8. Sodium, Cefoperazone

    9. T 1551

    10. T-1551

    11. T1551

    2.3.2 Depositor-Supplied Synonyms

    1. 62893-20-3

    2. Sodium Cefoperazone

    3. Cefoperazone Sodium Salt

    4. Cefobid

    5. Tomabef

    6. T-1551

    7. Cp 52640-2

    8. Cefoperazone (sodium Salt)

    9. Cefoperazone (as Sodium)

    10. 5fqg9774wd

    11. Chebi:3494

    12. Cp-52,640-2

    13. Nsc-758173

    14. 62893-20-3 (sodium)

    15. Cp-526402

    16. Cefobid (tn)

    17. Cp-52640-2

    18. Dsstox_cid_25874

    19. Dsstox_rid_81192

    20. Dsstox_gsid_45874

    21. Sodium;(6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    22. Cefobis

    23. 1094606-34-4

    24. Cas-62893-20-3

    25. Cefobid In Plastic Container

    26. Einecs 263-751-5

    27. T 1551

    28. Unii-5fqg9774wd

    29. Cefoperazin

    30. Cefoneg

    31. Cefoper

    32. Cefoperazon-natrium

    33. Ncgc00094952-01

    34. Cefobid Sodium Salt

    35. Sodium;(6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxy

    36. Cefoperazone Sodium [usan:usp:jan]

    37. Cefoperazone, Sodium Salt

    38. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-(p-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

    39. Schembl537680

    40. Chembl1200482

    41. Dtxsid6045874

    42. Hy-b0210a

    43. Cefoperazone Sodium [jan]

    44. Cefoperazone Sodium (jp17/usp)

    45. Cefoperazone Sodium [usan]

    46. Cefoperazone Sodium [vandf]

    47. Cefoperazone Sodium [mart.]

    48. Tox21_111367

    49. Cefoperazone Sodium [who-dd]

    50. Mfcd07793331

    51. Cefoperazone Sodium Salt [mi]

    52. Akos015951266

    53. Tox21_111367_1

    54. Ccg-270350

    55. Cs-5023

    56. Nsc 758173

    57. Cefoperazone Sodium [ep Impurity]

    58. Cefoperazone Sodium [orange Book]

    59. Ncgc00179599-03

    60. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-, Monosodium Salt, (6r-(6alpha,7beta(r*)))-

    61. Cefoperazone Sodium [ep Monograph]

    62. Cefoperazone Sodium [usp Monograph]

    63. C08112

    64. D00918

    65. Sulperazone Component Cefoperazone Sodium

    66. A834072

    67. Cefoperazone Sodium Component Of Sulperazone

    68. Q27106107

    69. Cefoperazone Sodium 100 Microg/ml In Acetonitrile:water

    70. (6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    71. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-(p-hydroxyphenyl)acetamido-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

    72. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    73. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1h-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    74. Sodium 7-[[2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    75. Sodium(6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    2.4 Create Date
    2008-02-05
    3 Chemical and Physical Properties
    Molecular Weight 667.7 g/mol
    Molecular Formula C25H26N9NaO8S2
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count13
    Rotatable Bond Count9
    Exact Mass667.12434545 g/mol
    Monoisotopic Mass667.12434545 g/mol
    Topological Polar Surface Area274 Ų
    Heavy Atom Count45
    Formal Charge0
    Complexity1250
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

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LTD","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"125","totalValueFC":"252150.3","currency":"USD","unitRateINR":"10575","date":"13-Aug-2024","totalValueINR":"21150000","totalValueInUsd":"252150.3","indian_port":"JNPT","hs_no":"29419090","bill_no":"5032660","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHEKOU","supplierAddress":"16F, JICHENG BUILDING NO.929, FENGHUANG MIDDLE, AVENUE, HONGGUTAN DISTRICT NANCHENG, JIANGXI JIANGXI, , C CHINA","customerAddress":"218\/219, 2ND FLOOR,KAILASH PLAZA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724178600,"product":"CEFOPERAZONE SODIUM (STERILE )IP","address":"AGARWAL B2B CENTRE, 604 KANCHPADA","city":"MUMBAI","supplier":"BRILLIANT PHARMACEUTICAL LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN RISE ENTERPRISES","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"115.5","totalValueFC":"116963.7","currency":"USD","unitRateINR":"9810.7","date":"21-Aug-2024","totalValueINR":"9810747","totalValueInUsd":"116963.7","indian_port":"JNPT","hs_no":"29419090","bill_no":"5176199","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"SHANGHAI","supplierAddress":"OFFICE F,32\/F, PLAZA 88 NO.88 YEUNGUK ROAD, TSUEN WAN, NT,HONG KONG, CN","customerAddress":"AGARWAL B2B CENTRE, 604 KANCHPADA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725388200,"product":"CEFOPERAZONE SODIUM IP","address":"218\/219, 2ND FLOOR,KAILASH PLAZA,","city":"GHATKOPAR EAST,MUMBAI, MAHARASTHRA","supplier":"JIANGXI IMPORT AND ","supplierCountry":"CHINA","foreign_port":"SHEKOU","customer":"AQUATIC REMEDIES PVT LTD","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"125","totalValueFC":"253128.8","currency":"USD","unitRateINR":"10606.3","date":"04-Sep-2024","totalValueINR":"21212500","totalValueInUsd":"253128.8","indian_port":"JNPT","hs_no":"29419090","bill_no":"5416455","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHEKOU","supplierAddress":"16F, JICHENG BUILDING NO.929, FENGH UANG MIDDLE, AVENUE, HONGGUTAN DIST RICT NANCHENG, JIANGXI JIANGXI, , C CHINA CHINA","customerAddress":"218\/219, 2ND FLOOR,KAILASH PLAZA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727029800,"product":"CEFOPERAZONE SODIUM STERILE IP2024","address":"13,VITHALDAS ROAD,BULAKHIDAS","city":"MUMBAI,MAHARASHTRA","supplier":"HENAN KANGDA PHARMACEUTICAL CO., LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"MEDI PHARMA DRUG ","customerCountry":"INDIA","quantity":"1030.00","actualQuantity":"1030","unit":"KGS","unitRateFc":"114.2","totalValueFC":"118747.2","currency":"USD","unitRateINR":"9661.3","date":"23-Sep-2024","totalValueINR":"9951159.6","totalValueInUsd":"118747.2","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"5748656","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"BEIJING","supplierAddress":"NO.66, JINGWU ROAD, XIANGCHENG CITY , HENAN PROVINCE, CHINA CHINA, , CH INA CHINA","customerAddress":"13,VITHALDAS ROAD,BULAKHIDAS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729103400,"product":"CEFOPERAZONE SODIUM STERILE IP(52 CTN)(LONGCHEM INTERNATIONAL TRADING COMPANYLIMITED)IUPAC- SODIUM(6R,7R)-7-{[(2R)-2-{[(CEFOPERAZONE SODIUM STERILE IP(52 CTN)(LONGCHEM INTERNATIONA","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"520.00","actualQuantity":"520","unit":"KGS","unitRateFc":"120","totalValueFC":"63011.5","currency":"USD","unitRateINR":"10182","date":"17-Oct-2024","totalValueINR":"5294640","totalValueInUsd":"63011.5","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29419090","bill_no":"6169584","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"305 AGGARWAL CITY SQUARE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729189800,"product":"CEFOPERAZONE SODIUM STERILE IP2024","address":"13,VITHALDAS ROAD,BULAKHIDAS","city":"MUMBAI,MAHARASHTRA","supplier":"HENAN KANGDA PHARMACEUTICAL CO., LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"MEDI PHARMA DRUG ","customerCountry":"INDIA","quantity":"1040.00","actualQuantity":"1040","unit":"KGS","unitRateFc":"114.2","totalValueFC":"120073.3","currency":"USD","unitRateINR":"9701.3","date":"18-Oct-2024","totalValueINR":"10089341.6","totalValueInUsd":"120073.3","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"6185884","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"BEIJING","supplierAddress":"NO.66, JINGWU ROAD, XIANGCHENG CITY , HENAN PROVINCE, CHINA CHINA, , CH INA CHINA","customerAddress":"13,VITHALDAS ROAD,BULAKHIDAS"}]
    06-Jan-2021
    18-Oct-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    01

    EDQM, Council of Europe

    Cefoperazone sodium - reference spectrum

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    Medlab Asia & Asia Health
    Not Confirmed

    EDQM, Council of Europe

    France
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    Medlab Asia & Asia Health
    Not Confirmed

    Cefoperazone sodium - reference spectrum

    CAS Number : n/a

    Quantity Per Vial : n/a

    Sale Unit : 1

    Order Code : C0684800

    Batch No : 1

    Price (€) : 79

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    02

    EDQM, Council of Europe

    Cefoperazone dihydrate

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    Medlab Asia & Asia Health
    Not Confirmed

    EDQM, Council of Europe

    France
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    Medlab Asia & Asia Health
    Not Confirmed

    Cefoperazone dihydrate

    CAS Number : 62893-19-0

    Quantity Per Vial : 100 mg

    Sale Unit : 1

    Order Code : C0684750

    Batch No : 2

    Price (€) : 79

    Storage : +5°C ± 3°C

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