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Chemistry

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Also known as: 118443-89-3, Cefquinome sulphate, Hr111v-sulfate, Cefquinome sulfate [usan], Hr111v-sulphate, (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;sulfuric acid
Molecular Formula
C23H26N6O9S3
Molecular Weight
626.7  g/mol
InChI Key
KYOHRXSGUROPGY-OFNLCGNNSA-N
FDA UNII
3858K104DQ

Cefquinome Sulfate
Cefquinome Sulfate is the sulfate form of cefquinome, a semisynthetic, broad-spectrum, fourth-generation aminothiazolyl cephalosporin with antibacterial activity. Cefquinome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
1 2D Structure

Cefquinome Sulfate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;sulfuric acid
2.1.2 InChI
InChI=1S/C23H24N6O5S2.H2O4S/c1-34-27-16(14-11-36-23(24)25-14)19(30)26-17-20(31)29-18(22(32)33)13(10-35-21(17)29)9-28-8-4-6-12-5-2-3-7-15(12)28;1-5(2,3)4/h4,6,8,11,17,21H,2-3,5,7,9-10H2,1H3,(H3-,24,25,26,30,32,33);(H2,1,2,3,4)/b27-16-;/t17-,21-;/m1./s1
2.1.3 InChI Key
KYOHRXSGUROPGY-OFNLCGNNSA-N
2.1.4 Canonical SMILES
CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC5=C4CCCC5)C(=O)[O-].OS(=O)(=O)O
2.1.5 Isomeric SMILES
CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC5=C4CCCC5)C(=O)[O-].OS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
3858K104DQ
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 118443-89-3

2. Cefquinome Sulphate

3. Hr111v-sulfate

4. Cefquinome Sulfate [usan]

5. Hr111v-sulphate

6. (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;sulfuric Acid

7. 3858k104dq

8. Unii-3858k104dq

9. 118443-88-2

10. 1-(((6r,7r)-7-((z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydroquinolin-1-ium Hydrogensulfate

11. Hr-111v-sulfate

12. Schembl988522

13. Cefquinome Sulfate [mi]

14. Chembl2103931

15. Cefquinome Sulfate [mart.]

16. Mfcd11864966

17. Akos025310170

18. Gs-3615

19. 1-(((6r,7r)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydroquinolinium Hydroxide, Inner Salt, 7(sup 2)-(z)-(o-methyloxime), Sulfate (1:1)

20. 1-{[(6r,7r)-7-[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-5,6,7,8-tetrahydroquinolin-1-ium; Sulfuric Acid

21. Quinolinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydro-, Hydroxide, Inner Salt, (6r-(6.alpha.,7.beta.(z)))-, Sulfate (1:1)

22. Quinolinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydro-, Hydroxide, Inner Salt, (6r-(6.alpha.,7.beta.(z)))-, Sulphate (1:1)

23. Quinolinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydro-, Hydroxide, Inner Salt, (6r-(6alpha,7beta(z)))-, Sulfate (1:1)

2.4 Create Date
2006-10-24
3 Chemical and Physical Properties
Molecular Weight 626.7 g/mol
Molecular Formula C23H26N6O9S3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Exact Mass626.09233995 g/mol
Monoisotopic Mass626.09233995 g/mol
Topological Polar Surface Area290 Ų
Heavy Atom Count41
Formal Charge0
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

API Reference Price

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[{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689618600,"product":"CEFQUINOME SULFATE STERILE CP (VET)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST","city":"MUMBAI","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"16.00","actualQuantity":"16","unit":"KGS","unitRateFc":"720","totalValueFC":"11668.6","currency":"USD","unitRateINR":"59940.2","date":"18-Jul-2023","totalValueINR":"959040.397","totalValueInUsd":"11668.6","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS OFF PODDAR PARK ROAD, MALAD EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729621800,"product":"CEFQUINOME SULFATE STERILE CP (VET)","address":"1101, 11TH FLOOR, DHUKKA CHAMBERS","city":"MUMBAI","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"UNICHEMIE INTERNATIONAL PRIVATE LIMITED","customerCountry":"INDIA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"700","totalValueFC":"2830.8","currency":"USD","unitRateINR":"59465","date":"23-Oct-2024","totalValueINR":"237860","totalValueInUsd":"2830.8","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"6294623","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"BEIJING","supplierAddress":"NO. 28, LICHENG AVE, LINYI COUNTY, SHANDONG, CHINA SDNF China","customerAddress":"1101, 11TH FLOOR, DHUKKA CHAMBERS"}]
18-Jul-2023
23-Oct-2024
KGS
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FDF Dossiers

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Dong Bang Co., Ltd

South Korea
Pharma, Lab & Chemical Expo
Not Confirmed
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Dong Bang Co., Ltd

South Korea
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Pharma, Lab & Chemical Expo
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Cefquinome sulfate

Brand Name : Cefnom

Dosage Form : Injectable

Dosage Strength : 25MG/ML

Packaging : 50ML, 100ML

Approval Date :

Application Number :

Regulatory Info :

Registration Country : South Korea

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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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03

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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 0.1G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 0.2G

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Application Number :

Regulatory Info :

Registration Country : China

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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 0.5G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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06

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Cefquinome Sulfate

Brand Name :

Dosage Form : Sterilized Injection

Dosage Strength : 2.5%/50ML

Packaging : 50ml/100ml/250ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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Cefquinome Sulfate

Brand Name :

Dosage Form : Sterilized Injection

Dosage Strength : 7.5%/100ML

Packaging : 50ml/100ml/250ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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08

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Cefquinome Sulfate

Brand Name :

Dosage Form : Intramammary Infusion

Dosage Strength : 75MG

Packaging : 8 g

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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Listed Dossiers

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01

Dong Bang Co., Ltd

South Korea
Pharma, Lab & Chemical Expo
Not Confirmed
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Dong Bang Co., Ltd

South Korea
arrow
Pharma, Lab & Chemical Expo
Not Confirmed

Cefquinome sulfate

Brand Name : Cefnom

Dosage Form : Injectable

Dosage Strength : 25MG/ML

Packaging : 50ML, 100ML

Approval Date :

Application Number :

Regulatory Info :

Registration Country : South Korea

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01

Dong Bang Co., Ltd

South Korea
Pharma, Lab & Chemical Expo
Not Confirmed
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Dong Bang Co., Ltd

South Korea
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Pharma, Lab & Chemical Expo
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Cefquinome sulfate

Dosage : Injectable

Dosage Strength : 25MG/ML

Brand Name : Cefnom

Approval Date :

Application Number :

Registration Country : South Korea

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02

Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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02

Pharma, Lab & Chemical Expo
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Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Dosage : Powder for Injection

Dosage Strength : 50MG

Brand Name :

Approval Date :

Application Number :

Registration Country : China

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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 0.1G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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Cefquinome Sulfate

Dosage : Powder for Injection

Dosage Strength : 0.1G

Brand Name :

Approval Date :

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Registration Country : China

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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 0.2G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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Cefquinome Sulfate

Dosage : Powder for Injection

Dosage Strength : 0.2G

Brand Name :

Approval Date :

Application Number :

Registration Country : China

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05

Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Brand Name :

Dosage Form : Powder for Injection

Dosage Strength : 0.5G

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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05

Pharma, Lab & Chemical Expo
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Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Dosage : Powder for Injection

Dosage Strength : 0.5G

Brand Name :

Approval Date :

Application Number :

Registration Country : China

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06

Pharma, Lab & Chemical Expo
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Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Brand Name :

Dosage Form : Sterilized Injection

Dosage Strength : 2.5%/50ML

Packaging : 50ml/100ml/250ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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06

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Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Dosage : Sterilized Injection

Dosage Strength : 2.5%/50ML

Brand Name :

Approval Date :

Application Number :

Registration Country : China

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07

Pharma, Lab & Chemical Expo
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Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Brand Name :

Dosage Form : Sterilized Injection

Dosage Strength : 7.5%/100ML

Packaging : 50ml/100ml/250ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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07

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
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Cefquinome Sulfate

Dosage : Sterilized Injection

Dosage Strength : 7.5%/100ML

Brand Name :

Approval Date :

Application Number :

Registration Country : China

blank

08

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

Cefquinome Sulfate

Brand Name :

Dosage Form : Intramammary Infusion

Dosage Strength : 75MG

Packaging : 8 g

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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08

Pharma, Lab & Chemical Expo
Not Confirmed
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arrow
Pharma, Lab & Chemical Expo
Not Confirmed

Cefquinome Sulfate

Dosage : Intramammary Infusion

Dosage Strength : 75MG

Brand Name :

Approval Date :

Application Number :

Registration Country : China

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ABOUT THIS PAGE

Cefquinome Sulfate Manufacturers

A Cefquinome Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cefquinome Sulfate, including repackagers and relabelers. The FDA regulates Cefquinome Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cefquinome Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cefquinome Sulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cefquinome Sulfate Suppliers

A Cefquinome Sulfate supplier is an individual or a company that provides Cefquinome Sulfate active pharmaceutical ingredient (API) or Cefquinome Sulfate finished formulations upon request. The Cefquinome Sulfate suppliers may include Cefquinome Sulfate API manufacturers, exporters, distributors and traders.

click here to find a list of Cefquinome Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cefquinome Sulfate GMP

Cefquinome Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cefquinome Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cefquinome Sulfate GMP manufacturer or Cefquinome Sulfate GMP API supplier for your needs.

Cefquinome Sulfate CoA

A Cefquinome Sulfate CoA (Certificate of Analysis) is a formal document that attests to Cefquinome Sulfate's compliance with Cefquinome Sulfate specifications and serves as a tool for batch-level quality control.

Cefquinome Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Cefquinome Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cefquinome Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Cefquinome Sulfate EP), Cefquinome Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cefquinome Sulfate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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