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Chemistry

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Also known as: Ceftiofur, 80370-57-6, Excenel, Ceftiofurum, Ceftiofur crystalline free acid, 83jl932i1c
Molecular Formula
C19H17N5O7S3
Molecular Weight
523.6  g/mol
InChI Key
ZBHXIWJRIFEVQY-IHMPYVIRSA-N
FDA UNII
83JL932I1C

Ceftiofur
Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity. Ceftiofur binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
1 2D Structure

Ceftiofur

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
2.1.2 InChI
InChI=1S/C19H17N5O7S3/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28)/b23-11-/t12-,16-/m1/s1
2.1.3 InChI Key
ZBHXIWJRIFEVQY-IHMPYVIRSA-N
2.1.4 Canonical SMILES
CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)O
2.1.5 Isomeric SMILES
CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CSC(=O)C4=CC=CO4)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
83JL932I1C
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ceftiofur

2. Ceftiofur Hydrochloride

3. Ceftiofur Sodium

4. U 64279a

5. U-64279e

2.3.2 Depositor-Supplied Synonyms

1. Ceftiofur

2. 80370-57-6

3. Excenel

4. Ceftiofurum

5. Ceftiofur Crystalline Free Acid

6. 83jl932i1c

7. Ceftiofur (inn)

8. Ceftiofur [inn]

9. (6r,7r)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7(sup 2)-(z)-(o-methyloxime), 2-furoate (ester)

10. (6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

11. Ceftiofurum [latin]

12. Naxcel [veterinary] (tn)

13. Ceftiofur [usan:inn:ban]

14. Unii-83jl932i1c

15. Hsdb 7445

16. Ncgc00167543-01

17. (6r,7r)-7-((z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((furan-2-carbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

18. Ceftiofur [mi]

19. Ceftiofur [hsdb]

20. Ceftiofur [mart.]

21. Ceftiofur [who-dd]

22. Dsstox_cid_26702

23. Dsstox_rid_81836

24. Dsstox_gsid_46702

25. Schembl332041

26. Chembl222913

27. Dtxsid7046702

28. Hy-n7102

29. Tox21_112540

30. Bdbm50103524

31. S5356

32. Zinc38141711

33. Akos015998831

34. Ccg-269876

35. Ceftiofur [ema Epar Veterinary]

36. Db11485

37. Cas-80370-57-6

38. Ceftiofur 100 Mug/ml In Acetonitrile/water

39. Cs-0081818

40. Ceftiofur 100 Microg/ml In Acetonitrile/water

41. D07657

42. 370c576

43. A839898

44. Ceftiofur Crystalline Free Acid [green Book]

45. Brd-k82960980-003-02-7

46. (6r,7r)-7-[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

47. (6r,7r)-7-[[(2z)-2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[[2-furanyl(oxo)methyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

48. (6r,7r)-7-[[(2z)-2-(2-azanyl-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-3-(furan-2-ylcarbonylsulfanylmethyl)-8-oxidanylidene-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

49. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, (6r-(6.alpha.,7.beta.(z)))-

50. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, (6r-(6alpha,7beta(z)))-

51. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, (6r,7r)-

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 523.6 g/mol
Molecular Formula C19H17N5O7S3
XLogP30.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count13
Rotatable Bond Count9
Exact Mass523.02901142 g/mol
Monoisotopic Mass523.02901142 g/mol
Topological Polar Surface Area256 Ų
Heavy Atom Count34
Formal Charge0
Complexity945
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Therapeutic Uses

MEDICATION (VET): Ceftiofur is used in the treatment of respiratory infections in cattle and pigs.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


THERAP CAT (VET): Antibacterial

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 334


MEDICATION (VET): Ceftiofur is an injectable cephalosporin approved for respiratory disease in horses and cattle and for treatment of canine bacterial urinary tract infections caused by E coli and Proteus.

Kahn, C.M. (Ed.); The Merck Veterinary Manual 9th ed. Merck & Co. Whitehouse Station, NJ. 2005, p. 2042


MEDICATION (VET): Dogs: ... Ceftiofur sodium for injection are indicated in the treatment of urinary tract infections caused by susceptible organisms, including E. coli, P. mirabilis, and S. aureus. /Ceftiofur sodium/

Thomson/Micromedex. USP Veterinary Pharmaceutical Information Monographs: Cephalolsporins (2003). Available from, as of July 26, 2006: https://www.usp.org/audiences/veterinary/monographs/main.html


For more Therapeutic Uses (Complete) data for CEFTIOFUR (13 total), please visit the HSDB record page.


4.2 Drug Warning

The cephalosporins are relatively nontoxic, ... . IM injections can be painful, and repeated IV administration may lead to local phlebitis. Nausea, vomiting, and diarrhea may occasionally be seen. Hypersensitivity reactions of several forms have been seen, particularly in animals with a history of acute penicillin allergy. Superinfection may arise with the use of cephalosporins, and Pseudomonas or Candida spp are likely opportunistic pathogens. /Cephalosporins/

Kahn, C.M. (Ed.); The Merck Veterinary Manual 9th ed. Merck & Co. Whitehouse Station, NJ. 2005, p. 2065


Ceftiofur is associated with a duration and dose-related thrombocytopenia and anemia in dogs, which would not be expected with the recommended dosage regimen.

Kahn, C.M. (Ed.); The Merck Veterinary Manual 9th ed. Merck & Co. Whitehouse Station, NJ. 2005, p. 2042


Ceftiofur concentrations in an infected and uninfected environment were compared and the efficacy of locally administered ceftiofur was evaluated in an experimental infection with Staphylococcus aureus in tissue cages. Eight ponies had tissue cages (TCs) implanted sc on each side of the neck. Into one of the cages 150 mg of ceftiofur was administered and fluid samples were taken to determine ceftiofur concentrations. After 1 week the other TC was infected with S. aureus and subsequently treated with 150 mg ceftiofur administered locally into the TC once daily for 21 days. Samples of fluid were taken to determine ceftiofur concentrations and for bacterial counts. Ceftiofur concentrations did not differ significantly in the infected and uninfected environments after single dose of 150 mg of ceftiofur. Concentrations were considerably in excess of the minimum inhibitory concentration (MIC) of the S. aureus strain used. A marked decrease of viable bacteria in tissue cage fluid (TCF) occurred. In five of seven ponies; however, the infection was not eliminated and abscess formation occurred. Therefore, local application of ceftiofur alone is not advisable for infections with S. aureus in secluded sites in horses, but should be used only with adjunctive therapy.

PMID:16420299 Bosch G et al; J Vet Pharmacol Ther 29 (1): 31-6 (2006)


Horses: Diarrhea with ceftiofur.

Thomson/Micromedex. USP Veterinary Pharmaceutical Information Monographs: Cephalolsporins (2003). Available from, as of July 26, 2006: https://www.usp.org/audiences/veterinary/monographs/main.html


Anemia and thrombocytopenia have been seen in dogs given ceftiofur at high doses (three to five times the labeled dose) or for long periods of time (5 to 6 weeks). These side effects appear to be reversible when treatment is discontinued.

Thomson/Micromedex. USP Veterinary Pharmaceutical Information Monographs: Cephalolsporins (2003). Available from, as of July 26, 2006: https://www.usp.org/audiences/veterinary/monographs/main.html


4.3 Drug Indication

* Pigs:

- Treatment of bacterial respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis and Streptococcus suis.

- Treatment of septicaemia, polyarthritis or polyserositis associated with Streptococcus suis infection.

* Cattle:

- Treatment of acute interdigital necrobacillosis in cattle also known as Panaritium or foot rot.

- Treatment of acute post-partum (puerperal) metritis in cattle, in cases where treatment with another antimicrobial has failed.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


5.2 ATC Code

QJ01DD90


5.3 Absorption, Distribution and Excretion

A study of 4 male and 4 female Sprague-Dawley rats treated intramuscularly with (14)C-ceftiofur (2 mg/kg bw) revealed that 55% of the administered dose was excreted in the urine and about 30% in the GI tract and feces. The major urinary metabolite was desfuroylceftiofur (DFC). The metabolism of ceftiofur was similar in calves administered (14)C-ceftiofur (2 mg/kg bw) via the i.m. route. Unmetabolized ceftiofur was also present in the urine (4.4-21% of total radioactivity).

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A group of Sprague-Dawley rats (7/sex) received single oral doses of (14)C-ceftiofur (200 mg/kg bw) in a comparative study with calves. Approximately 55% of the total dose was recovered in the urine and the rest was present in the feces and GI tract. Plasma concentration at 6 hr was 1 mg/kg and trace amounts of ceftiofur were present in all tissues (i.e. liver, muscle and fat). The highest residue levels (0.7 mg/kg) were present in kidney.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A study of lactating cows treated with (14)C-ceftiofur (2.3 mg/kg bw/day for 5 days) revealed that 32-38% of the radioactivity was present in the milk as free metabolites. The major metabolite was desfuroylceftiofur cysteine disulfide representing 7-9% of the total radioactivity. No parent compound was detected in the milk.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A study of im administration of (14)C-ceftiofur in a bull revealed that 55% of the administered dose was excreted in the urine and approximately 30% in the GI tract and feces. The initial metabolite in both urine and plasma was desfuroylceftiofur. HPLC analysis of radioactive metabolites was similar to the results found in the rat studies. A number of metabolites were produced, the major metabolite (87% of total urinary metabolites) being desfuroylceftiofur acetamide conjugates. No parent compound was observed in the urine.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


For more Absorption, Distribution and Excretion (Complete) data for CEFTIOFUR (13 total), please visit the HSDB record page.


5.4 Metabolism/Metabolites

A study of 4 male and 4 female Sprague-Dawley rats treated intramuscularly with (14)C-ceftiofur (2 mg/kg bw) revealed that 55% of the administered dose was excreted in the urine and about 30% in the GI tract and faeces. The major urinary metabolite was desfuroylceftiofur (DFC). The metabolism of ceftiofur was similar in calves administered (14)C-ceftiofur (2 mg/kg bw) via the i.m. route. Unmetabolized ceftiofur was also present in the urine (4.4-21% of total radioactivity).

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A group of Sprague-Dawley rats (7/sex) received single oral doses of (14)C-ceftiofur (200 mg/kg bw) in a comparative study with calves. Approximately 55% of the total dose was recovered in the urine and the rest was present in the feces and GI tract. ... The major urinary metabolite was ceftiofursulfoxide cysteine thioester.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


HPLC analysis of metabolites of (14)C-ceftiofur formed by arochlor-induced rat liver S-9 fractions in vitro revealed that desfuroylceftiofur was the major metabolite. Low doses (119 mg/kg bw) of ceftiofur were completely metabolized within 15 minutes. Higher doses (857 mg/kg bw) were converted to desfuroylceftiofur after 60 minutes of incubation.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A study in 8-week old Sprague-Dawley rats (7/sex) treated with (14)C-ceftiofur (800 mg/kg bw/day) by oral gavage for 5 days revealed several urinary metabolites, including desfuroylceftiofur, ceftiofur sulfoxide, and cysteine disulfide.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


For more Metabolism/Metabolites (Complete) data for CEFTIOFUR (15 total), please visit the HSDB record page.


5.5 Biological Half-Life

Six Friesian calves (3/sex) were treated with ceftiofur according to different protocols including one single im and iv injection at 1 mg/kg bw, and 5 i.m. injections at 1 mg/kg bw at 24 hr intervals. ... The half life (0.07 hr) was short due to rapid metabolism to desfuroylceftiofur. The t1/2 of desfuroylceftiofur after im and iv administration were similar (9.7 and 8.6 hr, respectively).

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A study of 4 calves (sex and breed unspecified) administered ceftiofur intramuscularly daily for 4 days at 2 dose levels (2.2 or 4.4 mg/kg bw/day) demonstrated a plasma half life of 3.5 hr. ... Plasma half life of the metabolite desfuroylceftiofur was 9.7 h after im administration.

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


A study of 4- to 5-month old Yorkshire-Hampshire pigs (6/sex) treated with 3 daily im injections of (14)C-ceftiofur (5.2 mg/kg bw) produced similar results to those observed in rats and cattle. ... The half life of desfuroylceftiofur was 13.5 hr after im treatment and 12.2 hr after iv treatment. /Desfuroylceftiofur/

Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 36: Toxicological Evaluation of Certain Veterinary Drug Residues in Food: Ceftiofur (1996). Available from, as of July 17, 2006: https://www.inchem.org/documents/jecfa/jecmono/v36je01.htm


5.6 Mechanism of Action

Ceftiofur sodium is a third generation broad-spectrum cephalosporin, formulated as an intramuscular injection, which is used to treat respiratory diseases in swine, ruminants and horses. The thioester bond on ceftiofur is rapidly cleaved to give desfuroylceftiofur which is further metabolized to a disulfide dimer and various desfuroylceftiofur-protein and amino acid conjugates.

PMID:16242891 Jacobson GA; Journal of Pharmaceutical and Biomedical Analysis 40 (5): 1249-1252 (2006)


Cephalosporins ... bind to penicillin-binding proteins located beneath the cell wall and thereby interfere with the action of transpeptidase and other cell-wall enzymes. A residual antibacterial effect is also evident with the cephalosporins. /Cephalosporins/

Kahn, C.M. (Ed.); The Merck Veterinary Manual 9th ed. Merck & Co. Whitehouse Station, NJ. 2005, p. 2063


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Date of Issue : 2022-07-15

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Date of Issue : 2019-07-22

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ceftiofur hydrochloride IH

Date of Issue : 2019-07-22

Valid Till : 2022-07-20

Written Confirmation Number : WC0131

Address of the Firm : Plot No 121-128, Sidco Industrial area, Alathur, Kancheepuram district, 603110

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PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"B.M.CHEMIE","customerCountry":"INDIA","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"345","totalValueFC":"26143.5","currency":"USD","unitRateINR":"25978.5","date":"05-Jul-2021","totalValueINR":"1948387.5","totalValueInUsd":"26143.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"4575359","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"BEIJING","supplierAddress":"","customerAddress":"108, MARINE CHEMBERS, 43, NEW MARINE LINES, BEHIND SNDT COLLEGE,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1631471400,"product":"CEFTIOFUR SODIUM VET (STERILE)","address":"108, MARINE CHEMBERS, 43, NEW MARINE LINES, BEHIND SNDT COLLEGE,","city":"MUMBAI","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"KUNMING","customer":"B.M.CHEMIE","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"340","totalValueFC":"34181.9","currency":"USD","unitRateINR":"25143","date":"13-Sep-2021","totalValueINR":"2514300","totalValueInUsd":"34181.9","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"5417119","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"KUNMING","supplierAddress":"","customerAddress":"108, MARINE CHEMBERS, 43, NEW MARINE LINES, BEHIND SNDT COLLEGE,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1636396200,"product":"CEFTIOFUR SODIUM STERILE VET I.P.","address":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI","city":"MUMBAI,MAHARASHTRA","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"B.M.CHEMIE","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"340","totalValueFC":"34492.5","currency":"USD","unitRateINR":"25687","date":"09-Nov-2021","totalValueINR":"2568700","totalValueInUsd":"34492.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"6182923","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637605800,"product":"CEFTIOFUR SODIUM STERILE VET(10CARTONS)","address":"304 AGGARWAL CITY SQUARE,MANGALAM","city":"DELHI,DELHI","supplier":"ZHEJIANG MEDICINE CO LTD","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"SHAH TC GLOBAL ","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"375.7","totalValueFC":"37885.6","currency":"USD","unitRateINR":"28213.9","date":"23-Nov-2021","totalValueINR":"2821391","totalValueInUsd":"37885.6","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29419090","bill_no":"1014327","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"N\/A","supplierAddress":"ZMC BUILDING 101-2 N ZHONGSHAN ROAD HANGZHOU 310003 CHINA","customerAddress":"304 AGGARWAL CITY SQUARE,MANGALAM"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643221800,"product":"CEFTIOFUR SODIUM STERILE (VET)","address":"304 AGGARWAL CITY SQUARE,MANGALAM","city":"DELHI,DELHI","supplier":"LONGCHEM INTERNATIONAL TRADING ","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC GLOBAL ","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"375.1","totalValueFC":"37914.5","currency":"USD","unitRateINR":"28243.9","date":"27-Jan-2022","totalValueINR":"2824385","totalValueInUsd":"37914.5","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29419090","bill_no":"1001566","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON, HO NGKONG HONG KONG","customerAddress":"304 AGGARWAL CITY SQUARE,MANGALAM"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1650997800,"product":"CEFTIOFUR SODIUM STERILE VET I.P.","address":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI","city":"MUMBAI,MAHARASHTRA","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"B.M.CHEMIE","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"340","totalValueFC":"52149.9","currency":"USD","unitRateINR":"26231","date":"27-Apr-2022","totalValueINR":"3934650","totalValueInUsd":"52149.9","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"8448996","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1661797800,"product":"CEFTIOFUR SODIUM STERILE VET I.P.","address":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI","city":"MUMBAI,MAHARASHTRA","supplier":"QILU PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NA","customer":"B.M. CHEMIE","customerCountry":"INDIA","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"325","totalValueFC":"49321.5","currency":"USD","unitRateINR":"26162.5","date":"30-Aug-2022","totalValueINR":"3924375","totalValueInUsd":"49321.5","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"2230704","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665426600,"product":"CEFTIOFUR SODIUM STERILE (VET)","address":"BEETAL HOUSE, 99, MADANGIR,BEHIND LOCAL SHOPPING CENTRE","city":"NEW DELHI,DELHI","supplier":"AMICOGEN CHINA BIOPHARM ","supplierCountry":"CHINA","foreign_port":"NA","customer":"DEL TRADE INTERNATIONAL ","customerCountry":"INDIA","quantity":"8.04","actualQuantity":"8.038","unit":"KGS","unitRateFc":"383","totalValueFC":"3084.8","currency":"USD","unitRateINR":"31578.4","date":"11-Oct-2022","totalValueINR":"253826.78","totalValueInUsd":"3084.8","indian_port":"DELHI AIR","hs_no":"29411090","bill_no":"2827000","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"BEETAL HOUSE, 99, MADANGIR,BEHIND LOCAL SHOPPING CENTRE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1680805800,"product":"CEFTIOFUR SODIUM STERILE VET I.P.","address":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI","city":"MUMBAI,MAHARASHTRA","supplier":"QILU SYNVA PHARMACEUTICAL CO LTD","supplierCountry":"CHINA","foreign_port":"NA","customer":"B.M. CHEMIE","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"320","totalValueFC":"32349.9","currency":"USD","unitRateINR":"26512","date":"07-Apr-2023","totalValueINR":"2651200","totalValueInUsd":"32349.9","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"5412202","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"502 JOLLY BHAVAN 2, 7 NEW MARINE, LINES CHURCHGATE MUMBAI"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1693247400,"product":"CEFTIOFUR SODIUM STERILE VET I.P.","address":"108, MARINE CHEMBERS, 43, NEW ,MARINE LINES, BEHIND SNDT COLLEGE, ,","city":"Mumbai","supplier":"QILU SYNVA PHARMACEUTICAL CO LIMITED","supplierCountry":"CHINA","foreign_port":"NA","customer":"B M CHEMIE","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"300","totalValueFC":"30324.5","currency":"USD","unitRateINR":"24868.5","date":"29-Aug-2023","totalValueINR":"2511966","totalValueInUsd":"30324.5","indian_port":"SAHAR AIR","hs_no":"29419090","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"NA","supplierAddress":"","customerAddress":"108, MARINE CHEMBERS, 43, NEW ,MARINE LINES, BEHIND SNDT COLLEGE, ,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722450600,"product":"CEFTIOFUR SODIUM STERILE (VET)","address":"BEETAL HOUSE, 99, MADANGIR","city":"NEW DELHI","supplier":"AMICOGEN CHINA BIOPHARM ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"DEL TRADE INTERNATIONAL ","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"273","totalValueFC":"275.2","currency":"USD","unitRateINR":"23082.2","date":"01-Aug-2024","totalValueINR":"23082.15","totalValueInUsd":"275.2","indian_port":"Delhi Air","hs_no":"29411090","bill_no":"4814376","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"BEIJING","supplierAddress":"NO 1688,SHIXIAN ROAD,JINING CITY SHANDONG PROVINCE,272073, P.R CHINA ,, CHINA CHINA","customerAddress":"BEETAL HOUSE, 99, MADANGIR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722623400,"product":"CEFTIOFUR SODIUM STERILE(VET)(5 CARTONS) IUPAC NAME:SODIUM;(6R,7R)-7-(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINOACE","address":"304 AGGARWAL CITY SQUARE,MANGALAM","city":"DELHI,DELHI","supplier":"LONGCHEM INTERNATIONAL TRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC GLOBAL ","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"233","totalValueFC":"11751.1","currency":"USD","unitRateINR":"19713.3","date":"03-Aug-2024","totalValueINR":"985664","totalValueInUsd":"11751.1","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29419090","bill_no":"1010073","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"SHANGHAI","supplierAddress":"N\/A","customerAddress":"304 AGGARWAL CITY SQUARE,MANGALAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724265000,"product":"CEFTIOFUR SODIUM STERILE (VET)(5 CTN)","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"LONGCHEM INTERNATIONAL TRADING CO.LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"233","totalValueFC":"11784.9","currency":"USD","unitRateINR":"19770.1","date":"22-Aug-2024","totalValueINR":"988502.5","totalValueInUsd":"11784.9","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"5185471","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER,61 MODY ROAD, TSIM SHA TSUI,KOWLOON HONG KONG","customerAddress":"305 AGGARWAL CITY SQUARE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727807400,"product":"CEFTIOFUR SODIUM CP(VET)","address":"BEETAL HOUSE, 99, MADANGIR","city":"NEW DELHI","supplier":"AMICOGEN CHINA BIOPHARM ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"DEL TRADE INTERNATIONAL ","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"273","totalValueFC":"6871.6","currency":"USD","unitRateINR":"23095.8","date":"02-Oct-2024","totalValueINR":"577395","totalValueInUsd":"6871.6","indian_port":"Delhi Air","hs_no":"29411090","bill_no":"5913732","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"NO 1688,SHIXIAN ROAD,JINING CITY SH ANDONG PROVINCE,272073, P.R CHINA , , CHINA CHINA","customerAddress":"BEETAL HOUSE, 99, MADANGIR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728498600,"product":"CEFTIOFUR SODIUM STERILE (VET) (40 CTN) IUPAC NAME:SODIUM;(6R,7R)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINOACCEFTIOFUR SODIUM STERILE (VET) (40 CTN) IUPAC NAME:SODIUM;(6","address":"304 AGGARWAL CITY SQUARE,MANGALAM","city":"DELHI,DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"PUDONG\/SHANGHAI","customer":"SHAH TC GLOBAL ","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"223","totalValueFC":"90080.9","currency":"USD","unitRateINR":"18923","date":"10-Oct-2024","totalValueINR":"7569187.65","totalValueInUsd":"90080.9","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29419090","bill_no":"6050042","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"PUDONG\/SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"304 AGGARWAL CITY SQUARE,MANGALAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729276200,"product":"CEFTIOFUR SODIUM STERILE (VET) (40 CTN) IUPAC NAME:SODIUM;(6R,7R)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINOACCEFTIOFUR SODIUM STERILE (VET) (40 CTN) IUPAC NAME:SODIUM;(6","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"SHAH TC GLOBAL ","supplierCountry":"CHINA","foreign_port":"PUDONG\/SHANGHAI","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"222.8","totalValueFC":"90090.6","currency":"USD","unitRateINR":"18925","date":"19-Oct-2024","totalValueINR":"7570000","totalValueInUsd":"90090.6","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29419090","bill_no":"6220653","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Sterile","supplierPort":"PUDONG\/SHANGHAI","supplierAddress":"304, AGGARWAL CITY SQUARE, MANGALAM PLACE, SECTOR-3, ROHINI, NORTH WES T DELHI, DELHI , DELHI,DELHI,110085 INDIA","customerAddress":"305 AGGARWAL CITY SQUARE"}]
01-Jan-2021
19-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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INTERMEDIATES SUPPLIERS

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01

Pharma, Lab & Chemical Expo
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CAS Number : 527-69-5

End Use API : Ceftiofur

About The Company : Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speci...

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FDF Dossiers

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01

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : CEVAXEL RTU

Dosage Form : SUSPENSION

Dosage Strength : 50MG/ML

Packaging : 50/100/250ML

Approval Date :

Application Number : 2458861

Regulatory Info : Prescription

Registration Country : Canada

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02

Dong Bang Co., Ltd

South Korea
Pharma, Lab & Chemical Expo
Not Confirmed
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Dong Bang Co., Ltd

South Korea
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Pharma, Lab & Chemical Expo
Not Confirmed

Ceftiofur

Brand Name : Cedium

Dosage Form : Injectable

Dosage Strength : 1000MG/GM

Packaging : 1G, 4G Vial

Approval Date :

Application Number :

Regulatory Info :

Registration Country : South Korea

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03

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

Ceftiofur

Brand Name :

Dosage Form : Injection

Dosage Strength : 250MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

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04

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

Ceftiofur

Brand Name :

Dosage Form : Injection

Dosage Strength : 500MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : India

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05

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

Ceftiofur

Brand Name :

Dosage Form : Sterilized Injection

Dosage Strength : 10%/50ML

Packaging : 50ml/100ml/250ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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06

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

Ceftiofur

Brand Name :

Dosage Form : Sterilized Injection

Dosage Strength : 20%/100ML

Packaging : 50ml/100ml/250ml

Approval Date :

Application Number :

Regulatory Info :

Registration Country : China

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07

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR SODIUM)

Brand Name : EXCENEL

Dosage Form : POWDER FOR SOLUTION

Dosage Strength : 50MG/ML

Packaging : 1G/4G

Approval Date :

Application Number : 813567

Regulatory Info : Prescription

Registration Country : Canada

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08

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : SPECTRAMAST LC

Dosage Form : SUSPENSION

Dosage Strength : 125MG/10ML

Packaging : 10ML

Approval Date :

Application Number : 2298325

Regulatory Info : Prescription

Registration Country : Canada

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09

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : SPECTRAMAST DC

Dosage Form : SUSPENSION

Dosage Strength : 500MG/10ML

Packaging : 10ML

Approval Date :

Application Number : 2312654

Regulatory Info : Prescription

Registration Country : Canada

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10

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR CRYSTALLINE FREE ACID)

Brand Name : EXCEDE 100

Dosage Form : SUSPENSION

Dosage Strength : 100MG/ML

Packaging : 100ML

Approval Date :

Application Number : 2305453

Regulatory Info : Prescription

Registration Country : Canada

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Canada

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01

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : CEVAXEL RTU

Dosage Form : SUSPENSION

Dosage Strength : 50MG/ML

Packaging : 50/100/250ML

Approval Date :

Application Number : 2458861

Regulatory Info : Prescription

Registration Country : Canada

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02

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR SODIUM)

Brand Name : EXCENEL

Dosage Form : POWDER FOR SOLUTION

Dosage Strength : 50MG/ML

Packaging : 1G/4G

Approval Date :

Application Number : 813567

Regulatory Info : Prescription

Registration Country : Canada

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03

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : SPECTRAMAST LC

Dosage Form : SUSPENSION

Dosage Strength : 125MG/10ML

Packaging : 10ML

Approval Date :

Application Number : 2298325

Regulatory Info : Prescription

Registration Country : Canada

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04

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR CRYSTALLINE FREE ACID)

Brand Name : EXCEDE 200

Dosage Form : SUSPENSION

Dosage Strength : 200MG/ML

Packaging : 100ML

Approval Date :

Application Number : 2360586

Regulatory Info : Prescription

Registration Country : Canada

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05

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : SPECTRAMAST DC

Dosage Form : SUSPENSION

Dosage Strength : 500MG/10ML

Packaging : 10ML

Approval Date :

Application Number : 2312654

Regulatory Info : Prescription

Registration Country : Canada

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06

Pharma, Lab & Chemical Expo
Not Confirmed
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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR CRYSTALLINE FREE ACID)

Brand Name : EXCEDE 100

Dosage Form : SUSPENSION

Dosage Strength : 100MG/ML

Packaging : 100ML

Approval Date :

Application Number : 2305453

Regulatory Info : Prescription

Registration Country : Canada

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07

Pharma, Lab & Chemical Expo
Not Confirmed
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CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : EXCENEL RTU EZ

Dosage Form : SUSPENSION

Dosage Strength : 50MG/ML

Packaging : 100ML/250ML

Approval Date :

Application Number : 2317214

Regulatory Info : Prescription

Registration Country : Canada

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LABORATORIOS HIPRA S.A.

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Pharma, Lab & Chemical Expo
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LABORATORIOS HIPRA S.A.

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Pharma, Lab & Chemical Expo
Not Confirmed

CEFTIOFUR (CEFTIOFUR HYDROCHLORIDE)

Brand Name : EFICUR

Dosage Form : SUSPENSION

Dosage Strength : 50MG/ML

Packaging : 50/100/250ML

Approval Date :

Application Number : 2443260

Regulatory Info : Prescription

Registration Country : Canada

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