Find Chlohexidine Gluconate manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Chlorhexidine gluconate, 1308292-96-7, Cid 9939931, Chembl1628, Schembl34467, Amy32023
Molecular Formula
C28H42Cl2N10O7
Molecular Weight
701.6  g/mol
InChI Key
KUXUALPOSMRJSW-IFWQJVLJSA-N

Chlohexidine Gluconate
Chlorhexidine Gluconate is the gluconate salt form of chlorhexidine, a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine gluconate is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine gluconate penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent.
1 2D Structure

Chlohexidine Gluconate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
2.1.2 InChI
InChI=1S/C22H30Cl2N10.C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2-5,7-11H,1H2,(H,12,13)/t;2-,3-,4+,5-/m.1/s1
2.1.3 InChI Key
KUXUALPOSMRJSW-IFWQJVLJSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl)N)N)Cl.C(C(C(C(C(C(=O)O)O)O)O)O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl.C(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 1,1'-hbcb

2. Avagard

3. Chlorhexamed

4. Chlorhexidine Bigluconate

5. Chlorhexidine Digluconate

6. Chlorhexidine Gluconate

7. Corsodyl Ici

8. Curasept Ads 220

9. Dyna-hex

10. Eludril

11. Gibitan

12. Hexidine

13. Hibiclens

14. Hibident

15. Hibiscrub

16. Hibisol

17. Hibitane

18. Peridex

19. Perio Chip

2.2.2 Depositor-Supplied Synonyms

1. Chlorhexidine Gluconate

2. 1308292-96-7

3. Cid 9939931

4. Chembl1628

5. Schembl34467

6. Amy32023

7. (1e)-2-[6-[[amino-[(e)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoic Acid

2.3 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 701.6 g/mol
Molecular Formula C28H42Cl2N10O7
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count9
Rotatable Bond Count18
Exact Mass700.2614991 g/mol
Monoisotopic Mass700.2614991 g/mol
Topological Polar Surface Area316 Ų
Heavy Atom Count47
Formal Charge0
Complexity819
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 3  
Drug NamePAROEX
Active IngredientCHLORHEXIDINE GLUCONATE
CompanySUNSTAR AMERICAS (Application Number: A076434)

2 of 3  
Drug NamePERIDEX
Active IngredientCHLORHEXIDINE GLUCONATE
Company3M (Application Number: N019028)

3 of 3  
Drug NamePERIOCHIP
Active IngredientCHLORHEXIDINE GLUCONATE
CompanyDEXCEL PHARMA (Application Number: N020774)

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Infective Agents, Local

Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects. (See all compounds classified as Anti-Infective Agents, Local.)


Dermatologic Agents

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Decreased Cell Wall Integrity [PE]

ABOUT THIS PAGE

Chlohexidine Gluconate Manufacturers

A Chlohexidine Gluconate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Chlohexidine Gluconate, including repackagers and relabelers. The FDA regulates Chlohexidine Gluconate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Chlohexidine Gluconate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Chlohexidine Gluconate Suppliers

A Chlohexidine Gluconate supplier is an individual or a company that provides Chlohexidine Gluconate active pharmaceutical ingredient (API) or Chlohexidine Gluconate finished formulations upon request. The Chlohexidine Gluconate suppliers may include Chlohexidine Gluconate API manufacturers, exporters, distributors and traders.

click here to find a list of Chlohexidine Gluconate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Chlohexidine Gluconate WC

A Chlohexidine Gluconate written confirmation (Chlohexidine Gluconate WC) is an official document issued by a regulatory agency to a Chlohexidine Gluconate manufacturer, verifying that the manufacturing facility of a Chlohexidine Gluconate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Chlohexidine Gluconate APIs or Chlohexidine Gluconate finished pharmaceutical products to another nation, regulatory agencies frequently require a Chlohexidine Gluconate WC (written confirmation) as part of the regulatory process.

click here to find a list of Chlohexidine Gluconate suppliers with Written Confirmation (WC) on PharmaCompass.

Chlohexidine Gluconate GMP

Chlohexidine Gluconate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Chlohexidine Gluconate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Chlohexidine Gluconate GMP manufacturer or Chlohexidine Gluconate GMP API supplier for your needs.

Chlohexidine Gluconate CoA

A Chlohexidine Gluconate CoA (Certificate of Analysis) is a formal document that attests to Chlohexidine Gluconate's compliance with Chlohexidine Gluconate specifications and serves as a tool for batch-level quality control.

Chlohexidine Gluconate CoA mostly includes findings from lab analyses of a specific batch. For each Chlohexidine Gluconate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Chlohexidine Gluconate may be tested according to a variety of international standards, such as European Pharmacopoeia (Chlohexidine Gluconate EP), Chlohexidine Gluconate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Chlohexidine Gluconate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty