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4 API Suppliers, 1 EU WC, 4 Listed Suppliers, $ API Reference Price

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FINISHED DOSAGE FORMULATIONS

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1 Canada
3 Listed Dossiers

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Synopsis

ACTIVE PHARMA INGREDIENTS

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API REF. PRICE (USD/KG)

$ 144

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Chemistry

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Also known as: 982-57-0, Chloramphenicol succinate sodium, Chloramphenicol monosuccinate sodium salt, Chloramphenicol succinate sodium, 872109hx6b, Protophenicol

Molecular Formula

C₁₅H₁₅Cl₂N₂NaO₈

Molecular Weight

445.2 g/mol

InChI Key

RPLOPBHEZLFENN-HTMVYDOJSA-M

FDA UNII

872109HX6B

Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity. Chloramphenicol sodium succinate reversibly binds to the 50S subunit of bacterial ribosomes, thereby interfering with peptidyl transferase activity in the elongation process of protein synthesis. As a result, this agent prevents bacterial cell growth.

1 2D Structure

Chloramphenicol Sodium Succinate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;4-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoate

2.1.2 InChI

InChI=1S/C15H16Cl2N2O8.Na/c16-14(17)15(24)18-10(7-27-12(22)6-5-11(20)21)13(23)8-1-3-9(4-2-8)19(25)26;/h1-4,10,13-14,23H,5-7H2,(H,18,24)(H,20,21);/q;+1/p-1/t10-,13-;/m1./s1

2.1.3 InChI Key

RPLOPBHEZLFENN-HTMVYDOJSA-M

2.1.4 Canonical SMILES

C1=CC(=CC=C1C(C(COC(=O)CCC(=O)[O-])NC(=O)C(Cl)Cl)O)[N+](=O)[O-].[Na+]

2.1.5 Isomeric SMILES

C1=CC(=CC=C1[C@H]([C@@H](COC(=O)CCC(=O)[O-])NC(=O)C(Cl)Cl)O)[N+](=O)[O-].[Na+]

2.2 Other Identifiers

2.2.1 UNII

872109HX6B

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Chloramphenicol Hemisuccinate

2. Chloramphenicol Monosuccinate

3. Chloramphenicol Succinate Sodium

4. Levomycetin Succinate

2.3.2 Depositor-Supplied Synonyms

1. 982-57-0

2. Chloramphenicol Succinate Sodium

3. Chloramphenicol Monosuccinate Sodium Salt

4. Chloramphenicol Succinate Sodium

5. 872109hx6b

6. Protophenicol

7. Dsstox_cid_4747

8. Dsstox_rid_77520

9. Dsstox_gsid_24747

10. Butanedioic Acid, Mono(2-((2,2-dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl) Ester, Monosodium Salt, (r-(r*,r*))-

11. Sodium Chloramphenicol Succinate

12. Chloramphenicol Sodium Monosuccinate

13. Cas-982-57-0

14. Sodium 4-((2r,3r)-2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propoxy)-4-oxobutanoate

15. Ccris 6204

16. Chloramphenicol-sukzinat-natrium

17. Ncgc00094619-04

18. Chloramphenicol Sodium Succinate, D-

19. Einecs 213-568-1

20. Chloramphenicol-sukzinat-natrium [german]

21. Unii-872109hx6b

22. Sodium;4-[(2r,3r)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoate

23. Chloramphenicol Sodium Succinate [usp:ban:jan]

24. Chloromycetin Succinate (tn)

25. D-threo-(-)-2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide Alpha-(sodium Succinate)

26. Schembl193134

27. Chloramphenicoli Natrii Succinas

28. Chembl1200729

29. Dtxsid2024747

30. Tox21_113484

31. Akos016340429

32. Tox21_113484_1

33. Ccg-212521

34. Ks-5158

35. Ncgc00094619-06

36. Acetamide, 2,2-dichloro-n-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)-, Alpha-ester With Sodium Succinate

37. Butanedioic Acid, Mono(2-((2,2-dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl) Ester, Monosodium Salt, (r-(r(sup *),r(sup *)))(-)

38. Chloramphenicol Sodium Succinate (jp17/usp)

39. Chloramphenicol Sodium Succinate [jan]

40. Chloramphenicol Sodium Succinate [vandf]

41. D02185

42. Chloramphenicol Sodium Succinate [mart.]

43. Chloramphenicol Sodium Succinate [who-dd]

44. Chloramphenicol Sodium Succinate [who-ip]

45. W-100087

46. Chloramphenicol Monosuccinate Sodium Salt [mi]

47. Chloramphenicol Sodium Succinate [ep Monograph]

48. Chloramphenicol Sodium Succinate [orange Book]

49. Chloramphenicoli Natrii Succinas [who-ip Latin]

50. Q27269783

51. Chloramphenicol Sodium Succinate [usp Monograph]

52. Butanedioic Acid, Mono((2r,3r)-2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl) Ester, Monosodium Salt

53. D-threo-(-)-2,2-dichloro-n-(.beta.-hydroxy-.alpha.-(hydroxymethyl)-p-nitrophenethyl)acetamide .alpha.-(sodium Succinate)

54. Sodium4-((2r,3r)-2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propoxy)-4-oxobutanoate

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₁₅Cl₂N₂NaO₈
Molecular Weight	445.2 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	9
Exact Mass	444.0103151 g/mol
Monoisotopic Mass	444.0103151 g/mol
Topological Polar Surface Area	162 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	541
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Chloramphenicol sodium succinate
Drug Label	IMPORTANT CONSIDERATIONS IN PRESCRIBING INJECTABLE CHLORAMPHENICOL SODIUM SUCCINATE.CHLORAMPHENICOL SODIUM SUCCINATE IS INTENDED FOR INTRAVENOUS USE ONLY. IT HAS BEENDEMONSTRATED TO BE INEFFECTIVE WHEN GIVEN INTRAMUSCULARLY.1. Chloramphenicol sodium...
Active Ingredient	Chloramphenicol sodium succinate
Dosage Form	Injectable
Route	Injection
Strength	eq 1gm base/vial
Market Status	Prescription
Company	Fresenius Kabi Usa

2 of 2
Drug Name	Chloramphenicol sodium succinate
Drug Label	IMPORTANT CONSIDERATIONS IN PRESCRIBING INJECTABLE CHLORAMPHENICOL SODIUM SUCCINATE.CHLORAMPHENICOL SODIUM SUCCINATE IS INTENDED FOR INTRAVENOUS USE ONLY. IT HAS BEENDEMONSTRATED TO BE INEFFECTIVE WHEN GIVEN INTRAMUSCULARLY.1. Chloramphenicol sodium...
Active Ingredient	Chloramphenicol sodium succinate
Dosage Form	Injectable
Route	Injection
Strength	eq 1gm base/vial
Market Status	Prescription
Company	Fresenius Kabi Usa

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Amphenicols [EXT]; Amphenicol-class Antibacterial [EPC]

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API Reference Price

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ABOUT THIS PAGE

Chloramphenicol Sodium Succinate Manufacturers

A Chloramphenicol Sodium Succinate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Chloramphenicol Sodium Succinate, including repackagers and relabelers. The FDA regulates Chloramphenicol Sodium Succinate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Chloramphenicol Sodium Succinate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Chloramphenicol Sodium Succinate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Chloramphenicol Sodium Succinate Suppliers

A Chloramphenicol Sodium Succinate supplier is an individual or a company that provides Chloramphenicol Sodium Succinate active pharmaceutical ingredient (API) or Chloramphenicol Sodium Succinate finished formulations upon request. The Chloramphenicol Sodium Succinate suppliers may include Chloramphenicol Sodium Succinate API manufacturers, exporters, distributors and traders.

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Chloramphenicol Sodium Succinate WC

A Chloramphenicol Sodium Succinate written confirmation (Chloramphenicol Sodium Succinate WC) is an official document issued by a regulatory agency to a Chloramphenicol Sodium Succinate manufacturer, verifying that the manufacturing facility of a Chloramphenicol Sodium Succinate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Chloramphenicol Sodium Succinate APIs or Chloramphenicol Sodium Succinate finished pharmaceutical products to another nation, regulatory agencies frequently require a Chloramphenicol Sodium Succinate WC (written confirmation) as part of the regulatory process.

click here to find a list of Chloramphenicol Sodium Succinate suppliers with Written Confirmation (WC) on PharmaCompass.

Chloramphenicol Sodium Succinate GMP

Chloramphenicol Sodium Succinate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Chloramphenicol Sodium Succinate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Chloramphenicol Sodium Succinate GMP manufacturer or Chloramphenicol Sodium Succinate GMP API supplier for your needs.

Chloramphenicol Sodium Succinate CoA

A Chloramphenicol Sodium Succinate CoA (Certificate of Analysis) is a formal document that attests to Chloramphenicol Sodium Succinate's compliance with Chloramphenicol Sodium Succinate specifications and serves as a tool for batch-level quality control.

Chloramphenicol Sodium Succinate CoA mostly includes findings from lab analyses of a specific batch. For each Chloramphenicol Sodium Succinate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Chloramphenicol Sodium Succinate may be tested according to a variety of international standards, such as European Pharmacopoeia (Chloramphenicol Sodium Succinate EP), Chloramphenicol Sodium Succinate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Chloramphenicol Sodium Succinate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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Chloramphenicol Sodium Succinate

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

4 API Suppliers

1 EU WC

4 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

10 FDF Dossiers

5 FDA Orange Book

1 Europe

1 Canada

3 Listed Dossiers

DIGITAL CONTENT

1 NEWS #PharmaBuzz

MARKET PLACE

5 APIs

REF. STANDARDS & IMPURITIES

1 EDQM

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 144

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

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REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

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Quantity (KGS) & Unit rate (USD/KGS) over time

01

North Medica A / S

North Medica A / S

01

SEARCHLIGHT PHARMA INC

SEARCHLIGHT PHARMA INC

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