List of Suppliers' Api Stability Enhancers Excipients Application used in Chlorcyclizine Hydrochloride on PharmaCompass.com

PharmaCompass

Synopsis

ACTIVE PHARMA INGREDIENTS

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

KDMF

KDMF

0

VMF

NDC API

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

132 RELATED EXCIPIENT COMPANIES

225EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Chlorcyclizine hcl, 1620-21-9, Histantin, Perazil, Di-paralene, 14362-31-3
Molecular Formula
C18H22Cl2N2
Molecular Weight
337.3  g/mol
InChI Key
MSIJLVMSKDXAQN-UHFFFAOYSA-N
FDA UNII
NPB7A7874U

Chlorcyclizine Hydrochloride
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
1 2D Structure

Chlorcyclizine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine;hydrochloride
2.1.2 InChI
InChI=1S/C18H21ClN2.ClH/c1-20-11-13-21(14-12-20)18(15-5-3-2-4-6-15)16-7-9-17(19)10-8-16;/h2-10,18H,11-14H2,1H3;1H
2.1.3 InChI Key
MSIJLVMSKDXAQN-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
NPB7A7874U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Azaron

2. Histantin

3. Pyribenzamine

4. Tripelennamine

5. Tripelennamine Citrate

6. Tripelennamine Citrate (1:1)

7. Tripelennamine Hydrochloride

8. Tripelennamine Maleate

9. Tripelennamine Maleate (1:1)

10. Tripelennamine Monohydrochloride

11. Vetibenzamin

2.3.2 Depositor-Supplied Synonyms

1. Chlorcyclizine Hcl

2. 1620-21-9

3. Histantin

4. Perazil

5. Di-paralene

6. 14362-31-3

7. Chlorcyclizinium Chloride

8. Eramide

9. Chlorcyclizine Monohydrochloride

10. Chlor Cyclizine Hydrochloride

11. Chlorcyclizine (hydrochloride)

12. Nsc-169496

13. 1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperazine Hydrochloride

14. Npb7a7874u

15. 1-(p-chlorobenzhydryl)-4-methylpiperazine Monohydrochloride

16. 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine;hydrochloride

17. Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, Monohydrochloride

18. Ah-289

19. 1620-21-9 (hcl)

20. 1-(p-chloro-alpha-phenylbenzyl)-4-methylpiperazine Monohydrochloride

21. (1-[(4-chlorophenyl)phenyl-methyl]-4-methylpiperazine)

22. Chlorcyclizine Chloride

23. Smr001233306

24. Einecs 238-335-1

25. Nsc 169496

26. Unii-npb7a7874u

27. Chlorcylizine

28. 1-[(4-chlorophenyl)(phenyl)methyl]-4-methylpiperazine Hydrochloride

29. Sr-05000001920

30. Chlorcyclizine Hydrochloride [usp]

31. Prestwick_967

32. Component Of Fedrazil

33. Ah-289 Hydrochloride

34. Diparalene Hydrochloride

35. Ncgc00016589-01

36. Cas-1620-21-9

37. Chlorocyclizine Hydrochloride

38. Dsstox_cid_25360

39. Dsstox_rid_80825

40. Di-paralene Monohydrochloride

41. Dsstox_gsid_45360

42. Mls002153967

43. Mls006010796

44. Schembl321657

45. Chembl1889091

46. Dtxsid7045360

47. Hms1570m13

48. Pharmakon1600-01500175

49. 1-(p-chloro-alpha-phenylbenzyl)-4-methylpiperazine Hydrochloride

50. Chlor Cyclizine-[d4] Hydrochloride

51. Tox21_110511

52. Mfcd00035329

53. Nsc169496

54. Nsc756678

55. Piperazine, 1-((4-chlorophenyl)phenylmethyl)-4-methyl-, Hydrochloride

56. Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-, Hydrochloride

57. Akos022181227

58. Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-, Monohydrochloride

59. Wln: T6m Dntj Dyr&r Dg &gh

60. Ccg-212523

61. Hy-112067a

62. Nsc 756678

63. Nsc-756678

64. Chlorcyclizine Hydrochloride [mi]

65. Wln: T6n Dntj Ayr&r Dg& D &gh

66. Chlorcyclizine Hydrochloride [mart.]

67. Chlorcyclizine Hydrochloride [vandf]

68. Chlorcyclizine Hydrochloride [who-dd]

69. Cs-0062684

70. Ft-0664522

71. Ft-0697779

72. F15109

73. Chlorcyclizine Hydrochloride [ep Monograph]

74. J-009887

75. Sr-05000001920-3

76. Q27284988

77. 1-(p-chlorobenzhydryl)-4-methylpiperazine Hydrochloride

78. 1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperazinexhydrochloride

79. 1-((4-chlorophenyl)phenylmethyl)-4-methylpiperazine Hydrochloride

80. 1-(p-chloro-.alpha.-phenylbenzyl)-4-methylpiperazine Hydrochloride

81. Chlorcyclizine Hydrochloride 1.0 Mg/ml In Methanol (as Free Base)

82. 1-((4-chlorophenyl)(phenyl)methyl)-4-methylpiperazine Xhydrochloride

83. 1-(p-chloro-.alpha.-phenylbenzyl)-4-methylpiperazine Monohydrochloride

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 337.3 g/mol
Molecular Formula C18H22Cl2N2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass336.1160041 g/mol
Monoisotopic Mass336.1160041 g/mol
Topological Polar Surface Area6.5 Ų
Heavy Atom Count22
Formal Charge0
Complexity300
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)


Anti-Allergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)


Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Fillers, Diluents & Binders

read-more
read-more

Direct Compression

read-more
read-more

Taste Masking

read-more
read-more

Thickeners and Stabilizers

read-more
read-more

Lubricants & Glidants

read-more
read-more

Disintegrants & Superdisintegrants

read-more
read-more

Chewable & Orodispersible Aids

read-more
read-more

Film Formers & Plasticizers

read-more
read-more

Co-Processed Excipients

read-more
read-more

Granulation

read-more
read-more

Parenteral

read-more
read-more

Coating Systems & Additives

read-more
read-more

Controlled & Modified Release

read-more
read-more

Topical

read-more
read-more

Emulsifying Agents

read-more
read-more

API Stability Enhancers

read-more
read-more

Solubilizers

read-more
read-more

Soft Gelatin

read-more
read-more

Rheology Modifiers

read-more
read-more

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty