Find Chlorhexadol manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Chlorhexadol, Lora, 3563-58-4, 2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol, Chloralodol [inn], W8rd4n93r2
Molecular Formula
C8H15Cl3O3
Molecular Weight
265.6  g/mol
InChI Key
QVFWZNCVPCJQOP-UHFFFAOYSA-N
FDA UNII
W8RD4N93R2

Chlorhexadol
Chlorhexadol is a sedative and hypnotic which is regulated in the United States as a Schedule III controlled substance. It is a derivative of chloral hydrate.
1 2D Structure

Chlorhexadol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol
2.1.2 InChI
InChI=1S/C8H15Cl3O3/c1-5(4-7(2,3)13)14-6(12)8(9,10)11/h5-6,12-13H,4H2,1-3H3
2.1.3 InChI Key
QVFWZNCVPCJQOP-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CC(C)(C)O)OC(C(Cl)(Cl)Cl)O
2.2 Other Identifiers
2.2.1 UNII
W8RD4N93R2
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Chlorhexadol

2. Lora

3. 3563-58-4

4. 2-methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol

5. Chloralodol [inn]

6. W8rd4n93r2

7. Mecoral

8. Chloralodol (inn)

9. Mechloral

10. Medodorm

11. Chloralodolum

12. Cloralodol

13. Cloralodol [inn-spanish]

14. Chloralodolum [inn-latin]

15. Einecs 222-634-9

16. Unii-w8rd4n93r2

17. Dea No. 2510

18. Chlorhexadol [mi]

19. Chloralodol [mart.]

20. Chloralodol [who-dd]

21. Schembl148160

22. Chembl2104116

23. Dtxsid8022795

24. Chebi:135097

25. Db01534

26. D07325

27. Q5102911

28. 2-methyl-4-[(2,2,2-trichloro-1-hydroxyethyl)oxy]pentan-2-ol

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 265.6 g/mol
Molecular Formula C8H15Cl3O3
XLogP32.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass264.008677 g/mol
Monoisotopic Mass264.008677 g/mol
Topological Polar Surface Area49.7 Ų
Heavy Atom Count14
Formal Charge0
Complexity179
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Pharmacology

Chloral hydrate has sedative/hypnotic activity which has been shown to extend the sleep of normal made adults via a dose-response relationship. [1]


4.2 ATC Code

N - Nervous system

N05 - Psycholeptics

N05C - Hypnotics and sedatives

N05CC - Aldehydes and derivatives

N05CC02 - Chloralodol


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ABOUT THIS PAGE

Chlorhexadol Manufacturers

A Chlorhexadol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Chlorhexadol, including repackagers and relabelers. The FDA regulates Chlorhexadol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Chlorhexadol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Chlorhexadol manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Chlorhexadol Suppliers

A Chlorhexadol supplier is an individual or a company that provides Chlorhexadol active pharmaceutical ingredient (API) or Chlorhexadol finished formulations upon request. The Chlorhexadol suppliers may include Chlorhexadol API manufacturers, exporters, distributors and traders.

click here to find a list of Chlorhexadol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Chlorhexadol GMP

Chlorhexadol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Chlorhexadol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Chlorhexadol GMP manufacturer or Chlorhexadol GMP API supplier for your needs.

Chlorhexadol CoA

A Chlorhexadol CoA (Certificate of Analysis) is a formal document that attests to Chlorhexadol's compliance with Chlorhexadol specifications and serves as a tool for batch-level quality control.

Chlorhexadol CoA mostly includes findings from lab analyses of a specific batch. For each Chlorhexadol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Chlorhexadol may be tested according to a variety of international standards, such as European Pharmacopoeia (Chlorhexadol EP), Chlorhexadol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Chlorhexadol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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