Find Chloroacetyl Chloride manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Related ProductsRelated Products

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 79-04-9, 2-chloroacetyl chloride, Acetyl chloride, chloro-, Chloracetyl chloride, Chloroacetic chloride, Monochloroacetyl chloride
Molecular Formula
C2H2Cl2O
Molecular Weight
112.94  g/mol
InChI Key
VGCXGMAHQTYDJK-UHFFFAOYSA-N
FDA UNII
K5UML06YUO

Chloroacetyl Chloride
1 2D Structure

Chloroacetyl Chloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-chloroacetyl chloride
2.1.2 InChI
InChI=1S/C2H2Cl2O/c3-1-2(4)5/h1H2
2.1.3 InChI Key
VGCXGMAHQTYDJK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C(C(=O)Cl)Cl
2.2 Other Identifiers
2.2.1 UNII
K5UML06YUO
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Monochloroacetyl Chloride

2.3.2 Depositor-Supplied Synonyms

1. 79-04-9

2. 2-chloroacetyl Chloride

3. Acetyl Chloride, Chloro-

4. Chloracetyl Chloride

5. Chloroacetic Chloride

6. Monochloroacetyl Chloride

7. Chloroacetylchloride

8. Chloroacetic Acid Chloride

9. Chlorure De Chloracetyle

10. Chloracetylchloride

11. Chlorid Kyseliny Chloroctove

12. Chloro Acetyl Chloride

13. Chloro-acetyl Chloride

14. Chloroethanoyl Chloride

15. K5uml06yuo

16. Acetyl Chloride, 2-chloro-

17. Monochloroacetic Acid Chloride

18. .alpha.-chloroacetyl Chloride

19. Chebi:34624

20. Mfcd00000725

21. Ccris 9145

22. Hsdb 973

23. Chlorure De Chloracetyle [french]

24. Chlorid Kyseliny Chloroctove [czech]

25. Einecs 201-171-6

26. Unii-k5uml06yuo

27. Un1752

28. Brn 0605439

29. Chloroacetylchlonde

30. Chloroacetylchoride

31. Chloroactylchloride

32. Chloroacetylchlorid

33. Chloro Acetylchlorid

34. Chloroacetyl Choride

35. Chloroactyl Chloride

36. Choroacetyl Chloride

37. Chioroacetyl Chloride

38. Chloro-acetylchloride

39. Chloroacetyl-chloride

40. Chloro Acetylchloride

41. Ch2clcocl

42. Clch2cocl

43. Chloro-actyl Chloride

44. Chloroacethyl Chloride

45. 2-chloroacetylchloride

46. Chloroacetyl Chloride-

47. A-chloroacetyl Chloride

48. 2-chloro Acetylchloride

49. 2-chloro-acetylchloride

50. 2-chloroacetic Chloride

51. Alpha-chloroacetylchloride

52. 2-chloro-acetyl Chloride

53. Alpha-chloro-acetylchloride

54. Dsstox_cid_6472

55. Alpha-chloroacetyl Chloride

56. Ec 201-171-6

57. 2-chloranylethanoyl Chloride

58. Schembl9584

59. 2-chloroacetic Acid Chloride

60. Chloroacetyl Chloride, 98%

61. Dsstox_rid_78120

62. Dsstox_gsid_26472

63. Chembl3187685

64. Dtxsid4026472

65. Chloracetyl Chloride [mi]

66. Amy40193

67. Bcp25293

68. Zinc3860850

69. Chloroacetyl Chloride [hsdb]

70. Tox21_200644

71. Bbl013127

72. Stk399762

73. Akos000121312

74. Un 1752

75. Cas-79-04-9

76. Ncgc00248777-01

77. Ncgc00258198-01

78. Vs-03683

79. Chloroacetyl Chloride [un1752] [poison]

80. Chloroacetyl Chloride, Purum, >=99.0% (gc)

81. A839561

82. Q411258

83. J-520024

84. F2190-0033

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 112.94 g/mol
Molecular Formula C2H2Cl2O
XLogP31.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass111.9482701 g/mol
Monoisotopic Mass111.9482701 g/mol
Topological Polar Surface Area17.1 Ų
Heavy Atom Count5
Formal Charge0
Complexity42.9
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 Metabolism/Metabolites

Oxidation of the vinyl halide carcinogen and hepatotoxin vinylidene chloride (VDC) by microsomal cytochrome p450 yields 2,2-dichloroacetaldehyde, 2-chloroacetyl chloride, 2-chloroacetic acid, and l,l-dichloroethylene oxide. The roles of these metabolites in covalent modification of proteins and reduced glutathione (GSH) were examined. 2-Chloroacetyl chloride reacted with model thiols at least 10(3)-fold faster than did l,l-dichloroethylene oxide and at least 10(5)-fold faster than did 2,2-dichloroacetaldehyde or 2-chloroacetic acid.

PMID:3965130 Liebler DC et al; Cancer Res 45 (1): 186-93 (1985)


Market Place

Do you need sourcing support? Ask us

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty