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4 RELATED EXCIPIENT COMPANIES

7EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 327-97-9, 3-o-caffeoylquinic acid, Heriguard, 3-(3,4-dihydroxycinnamoyl)quinic acid, 3-caffeoylquinic acid, Chlorogenate
Molecular Formula
C16H18O9
Molecular Weight
354.31  g/mol
InChI Key
CWVRJTMFETXNAD-JUHZACGLSA-N
FDA UNII
318ADP12RI

Chlorogenic Acid
A naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats. (From J Chromatogr A 1996;741(2):223-31; Biosci Biotechnol Biochem 1996;60(5):765-68).
1 2D Structure

Chlorogenic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic acid
2.1.2 InChI
InChI=1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1
2.1.3 InChI Key
CWVRJTMFETXNAD-JUHZACGLSA-N
2.1.4 Canonical SMILES
C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O
2.1.5 Isomeric SMILES
C1[C@H]([C@H]([C@@H](C[C@@]1(C(=O)O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
318ADP12RI
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3 Caffeoylquinic Acid

2. 3-caffeoylquinic Acid

3. Acid, 3-caffeoylquinic

4. Acid, Chlorogenic

2.3.2 Depositor-Supplied Synonyms

1. 327-97-9

2. 3-o-caffeoylquinic Acid

3. Heriguard

4. 3-(3,4-dihydroxycinnamoyl)quinic Acid

5. 3-caffeoylquinic Acid

6. Chlorogenate

7. Hlorogenic Acid

8. Cp Chlorogenic Acid

9. Nsc-407296

10. Caffeoyl Quinic Acid

11. 5-cqa

12. (+)-chlorogenic Acid

13. Chlorogenic Acid [mi]

14. 5-o-(3,4-dihydroxycinnamoyl)-l-quinic Acid

15. Trans-chlorogenic Acid

16. Caffetannic Acid

17. Trans-caffeic Acid 5-o-d-quinate

18. Chlorogenic Acid [who-dd]

19. Cis-chlorogenic Acid

20. Nsc 70861

21. Nsc-70861

22. (1s,3r,4r,5r)-3-[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic Acid

23. Nsc 407296

24. Trans-5-o-caffeoylquinic Acid

25. 318adp12ri

26. Chembl284616

27. 202650-88-2

28. Chebi:16112

29. Cyclohexanecarboxylic Acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-, (1s-(1-alpha,3-beta,4-alpha,5-alpha))-

30. Chlorogenic Acid (constituent Of St. John's Wort) [dsc]

31. Mfcd00003862

32. 3-o-(3,4-dihydroxycinnamoyl)-d-quinic Acid

33. (1s,3r,4r,5r)-3-{[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic Acid

34. Chlorogenic Acid (constituent Of Echinacea Angustifolia Root, Echinacea Pallida Root, Echinacea Purpurea Root And Echinacea Purpurea Aerial Parts) [dsc]

35. Cyclohexanecarboxylic Acid, 3-(((2e)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl)oxy)-1,4,5-trihydroxy-, (1s,3r,4r,5r)-

36. Cyclohexanecarboxylic Acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-, (1s,3r,4r,5r)-

37. Cyclohexanecarboxylic Acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, (1s,3r,4r,5r)-

38. Chlorogenicacid

39. Caffeoylquinic Acid

40. 1,3,4,5-tetrahydroxycyclohexanecarboxylic Acid 3-(3,4-dihydroxycinnamate)

41. 3-o-caffeoyl-d-quinic Acid

42. 1,3,4,5-tetrahydroxycyclohexanecarboxylic Acid 3-(3,4-dihydroxycinnamate

43. 3-caffeoylquinate

44. 5-caffeoylquinic Acid

45. 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy] 1,4,5-trihydroxycyclohexanecarboxylic Acid

46. 5-caffeoyl Quinic Acid

47. (1s,3r,4r,5r)-3-(((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexanecarboxylic Acid

48. [1s-(1alpha,3beta,4alpha,5alpha)]-3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic Acid

49. [1s-(1alpha,3beta,4alpha,5alpha)]3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic Acid

50. Cyclohexanecarboxylic Acid, 3-[[(2e)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, (1s,3r,4r,5r)-

51. Cyclohexanecarboxylic Acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, [1s-(1alpha,3beta,4alpha,5alpha)]-

52. Ccris 1400

53. Einecs 206-325-6

54. 3-trans-caffeoylquinic Acid

55. Unii-318adp12ri

56. Hlorogenate

57. Helianthic Acid

58. Igasuric Acid

59. Nsc70861

60. Chlorogenic-acid

61. Nsc407296

62. Caffeylquinic Acid

63. 3-(3,4-dihydroxycinnamoyl)quinate

64. Prestwick_112

65. (e)-chlorogenic Acid

66. Hoodia Chinese Extract

67. Chlorogenic Acid, Chiral

68. Chlorogenic Acid (8ci)

69. Prestwick2_000427

70. Prestwick3_000427

71. Spectrum5_000733

72. Bmse000387

73. Quinic Acid, 5-caffeoyl-

74. Schembl19466

75. Bspbio_000414

76. Bspbio_003353

77. Spectrum210800

78. Mls002153805

79. Bidd:er0453

80. Bpbio1_000456

81. Quinic Acid, 3-caffeoyl-, E-

82. Acon1_000581

83. Chebi:95271

84. Chlorogenic Acid [usp-rs]

85. Bdbm513080

86. Dtxsid101318952

87. Hms1569e16

88. Hms1923c11

89. Hms2096e16

90. Hms2235f03

91. Hms3649e06

92. Act03375

93. Albb-030169

94. Cga

95. Hy-n0055

96. Zinc2138728

97. Bdbm50327036

98. Ccg-38471

99. S2280

100. Akos015955866

101. Ac-6032

102. Chlorogenic Acid, >=95% (titration)

103. Cs-3766

104. Db12029

105. Sdccgmls-0066467.p001

106. Ncgc00168941-01

107. Ncgc00168941-02

108. Ncgc00168941-03

109. (1s,3r,4r,5r)-3-(((e)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexane-1-carboxylic Acid

110. (1s,3r,4r,5r)-3-[(e)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic Acid

111. As-12284

112. Smr000857273

113. Chlorogenic Acid 100 Microg/ml In Methanol

114. Chlorogenic Acid 1000 Microg/ml In Acetone

115. Chlorogenic Acid 10 Microg/ml In Acetonitrile

116. C00852

117. F16266

118. 327c979

119. Q421964

120. Sr-01000841185

121. Sr-01000946600

122. D54cae3d-cdda-455d-a28e-77fc9efe4a43

123. Sr-01000841185-4

124. Sr-01000946600-1

125. Brd-k47114202-001-06-2

126. 32cf6d13-8f08-485f-b79e-f8a6ac318e07

127. Chlorogenic Acid, Primary Pharmaceutical Reference Standard

128. Chlorogenic Acid, European Pharmacopoeia (ep) Reference Standard

129. Chlorogenic Acid, United States Pharmacopeia (usp) Reference Standard

130. 3-[(e)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic Acid

131. 3-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic Acid

132. (1r,3s,4s,5s)-3-[(e)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic Acid

133. (1s,3r,4r,5r)-3-(((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexanecarboxylicacid

134. (1s,3r,4r,5r)-3-(((e)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexanecarboxylic Acid

135. (1s,3r,4r,5r)-3-((e)-3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4,5-trihydroxycyclohexanecarboxylic Acid

136. (1s,3r,4r,5r)-3-[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxy-cyclohexanecarboxylic Acid

137. (1s,3r,4r,5r)-3-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxycyclohexanecarboxylic Acid

138. (1s,3r,4r,5r,e)-3-(3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4,5-trihydroxycyclohexanecarboxylic Acid

139. Cyclohexanecarboxylic Acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-, (1s-(1-.alpha.,3-.beta.,4-.alpha.,5-.alpha.))-

140. Cyclohexanecarboxylic Acid,3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-,(1s,3r,4r,5r)-

141. Edit(1s,3r,4r,5r)-3-{[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic Acid

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 354.31 g/mol
Molecular Formula C16H18O9
XLogP3-0.4
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass354.09508215 g/mol
Monoisotopic Mass354.09508215 g/mol
Topological Polar Surface Area165 Ų
Heavy Atom Count25
Formal Charge0
Complexity534
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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06-Mar-2021
11-Jun-2024
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Chlorogenic Acid Manufacturers

A Chlorogenic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Chlorogenic Acid, including repackagers and relabelers. The FDA regulates Chlorogenic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Chlorogenic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Chlorogenic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Chlorogenic Acid Suppliers

A Chlorogenic Acid supplier is an individual or a company that provides Chlorogenic Acid active pharmaceutical ingredient (API) or Chlorogenic Acid finished formulations upon request. The Chlorogenic Acid suppliers may include Chlorogenic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of Chlorogenic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Chlorogenic Acid GMP

Chlorogenic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Chlorogenic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Chlorogenic Acid GMP manufacturer or Chlorogenic Acid GMP API supplier for your needs.

Chlorogenic Acid CoA

A Chlorogenic Acid CoA (Certificate of Analysis) is a formal document that attests to Chlorogenic Acid's compliance with Chlorogenic Acid specifications and serves as a tool for batch-level quality control.

Chlorogenic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Chlorogenic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Chlorogenic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Chlorogenic Acid EP), Chlorogenic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Chlorogenic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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