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Chemistry

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Also known as: 95522-45-5, Colestimide, Colestilan chloride, 2-(chloromethyl)oxirane;2-methyl-1h-imidazole, Cholebine, 1h-imidazole, 2-methyl-, polymer with (chloromethyl)oxiraneother ca index names:oxirane, (chloromethyl)-, polymer with 2-methyl-1h-imidazole
Molecular Formula
C7H11ClN2O
Molecular Weight
174.63  g/mol
InChI Key
DEMLYXMVPJAVFU-UHFFFAOYSA-N

Cholebine
Colestilan is an ingredient in the EMA-withdrawn product BindRen.
1 2D Structure

Cholebine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(chloromethyl)oxirane;2-methyl-1H-imidazole
2.1.2 InChI
InChI=1S/C4H6N2.C3H5ClO/c1-4-5-2-3-6-4;4-1-3-2-5-3/h2-3H,1H3,(H,5,6);3H,1-2H2
2.1.3 InChI Key
DEMLYXMVPJAVFU-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=NC=CN1.C1C(O1)CCl
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Cholebine

2. Mci-196

2.2.2 Depositor-Supplied Synonyms

1. 95522-45-5

2. Colestimide

3. Colestilan Chloride

4. 2-(chloromethyl)oxirane;2-methyl-1h-imidazole

5. Cholebine

6. 1h-imidazole, 2-methyl-, Polymer With (chloromethyl)oxiraneother Ca Index Names:oxirane, (chloromethyl)-, Polymer With 2-methyl-1h-imidazole

7. Colestilan [inn]

8. Unii-vsi302rysr

9. Colestilan Chloride [usan]

10. Epichlorohydrin-2-methylimidazole Copolymer

11. Mci 196

12. Mci-196

13. 2-(chloromethyl)oxirane; 2-methyl-1h-imidazole

14. Cholebine (japan)

15. Vsi302rysr

16. Schembl1649186

17. 2-methylimidazole Polymer With 1-chloro-2,3-epoxypropane

18. Dtxsid40914950

19. Q4117076

20. 2-(chloromethyl)oxirane--2-methyl-1h-imidazole (1/1)

21. 1h-imidazole, 2-methyl-, Polymer With (chloromethyl)oxirane

22. Oxirane, (chloromethyl)-, Polymer With 2-methyl-1h-imidazole

2.3 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 174.63 g/mol
Molecular Formula C7H11ClN2O
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass174.0559907 g/mol
Monoisotopic Mass174.0559907 g/mol
Topological Polar Surface Area41.2 Ų
Heavy Atom Count11
Formal Charge0
Complexity82.7
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Indication

Treatment of hyperphosphataemia in adult patients with chronic kidney disease stage 5 receiving haemodialysis or peritoneal dialysis.


Treatment of hyperphosphataemia


5 Pharmacology and Biochemistry
5.1 ATC Code

V03AE


V - Various

V03 - All other therapeutic products

V03A - All other therapeutic products

V03AE - Drugs for treatment of hyperkalemia and hyperphosphatemia

V03AE06 - Colestilan


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