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Also known as: 856676-23-8, Trilipix, Unii-4bmh7izt98, Abt-335, 2-hydroxy-n,n,n-trimethylethanaminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate, Fibricor
Molecular Formula
C22H28ClNO5
Molecular Weight
421.9  g/mol
InChI Key
JWAZHODZSADEHB-UHFFFAOYSA-M
FDA UNII
4BMH7IZT98

Choline Fenofibrate
Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
1 2D Structure

Choline Fenofibrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate;2-hydroxyethyl(trimethyl)azanium
2.1.2 InChI
InChI=1S/C17H15ClO4.C5H14NO/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11;1-6(2,3)4-5-7/h3-10H,1-2H3,(H,20,21);7H,4-5H2,1-3H3/q;+1/p-1
2.1.3 InChI Key
JWAZHODZSADEHB-UHFFFAOYSA-M
2.1.4 Canonical SMILES
CC(C)(C(=O)[O-])OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl.C[N+](C)(C)CCO
2.2 Other Identifiers
2.2.1 UNII
4BMH7IZT98
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic Acid

2. Abt 335

3. Abt-335

4. Abt335

2.3.2 Depositor-Supplied Synonyms

1. 856676-23-8

2. Trilipix

3. Unii-4bmh7izt98

4. Abt-335

5. 2-hydroxy-n,n,n-trimethylethanaminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

6. Fibricor

7. Fenofibric Acid Choline Salt

8. 4bmh7izt98

9. Abt 335

10. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate;2-hydroxyethyl(trimethyl)azanium

11. 2-hydroxy-n,n,n-trimethylethanaminium 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

12. Ethanaminium, 2-hydroxy-n,n,n-trimethyl-, Salt With 2-(4-(4- Chlorobenzoyl)phenoxy)-2-methylpropanoic Acid (1:1)

13. Fenofibrate De Choline

14. Choline Fenofibrate [usan]

15. Choline Fenofibrate [usan:inn]

16. Choline Fenofibrate (abt-335)

17. Hip0901

18. Trilipix (tn)

19. Choline Fenofibrate;abt-335

20. Chembl1201745

21. Choline Fenofibrate (usan/inn)

22. Choline Fenofibrate [inn]

23. Dtxsid50234939

24. Bcp28592

25. Choline Fenofibrate [mart.]

26. Choline Fenofibrate [usp-rs]

27. Choline Fenofibrate [who-dd]

28. Mfcd18382233

29. Akos016010592

30. Cs-0893

31. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium

32. 2-hydroxy-n,n,n-trimethylethanaminium2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

33. Choline Fenofibrate [orange Book]

34. As-10210

35. Fenofibric Acid Choline Salt [mi]

36. Hy-14739

37. Ft-0665026

38. D08890

39. D70702

40. A863484

41. Q27259379

42. 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic Acid Choline Salt

43. 2-hydroxy-n,n,n-trimethylethan-1-aminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate

44. 2-hydroxy-n,n,n-trimethylethanaminium 2-(-(4-chlorobenzoyl)phenoxy)-2- Methylpropanoate

45. 2-hydroxy-n,n,n-trimethylethanaminium 2-(4-(4-chlorobenzoyl)phenoxy)-2- Methylpropanoate

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 421.9 g/mol
Molecular Formula C22H28ClNO5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass421.1656007 g/mol
Monoisotopic Mass421.1656007 g/mol
Topological Polar Surface Area86.7 Ų
Heavy Atom Count29
Formal Charge0
Complexity446
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 ATC Code

C - Cardiovascular system

C10 - Lipid modifying agents

C10A - Lipid modifying agents, plain

C10AB - Fibrates

C10AB11 - Choline fenofibrate


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05-Jan-2021
29-Oct-2024
KGS
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DOSAGE - CAPSULE, DELAYED RELEASE;ORAL - EQ 1...DOSAGE - CAPSULE, DELAYED RELEASE;ORAL - EQ 135MG FENOFIBRIC ACID

USFDA APPLICATION NUMBER - 22224

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DOSAGE - CAPSULE, DELAYED RELEASE;ORAL - EQ 4...DOSAGE - CAPSULE, DELAYED RELEASE;ORAL - EQ 45MG FENOFIBRIC ACID

USFDA APPLICATION NUMBER - 22224

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