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ACTIVE PHARMA INGREDIENTS

8 API Suppliers, 3 CEP/COS, 2 EU WC, 4 Listed Suppliers, $ API Reference Price

8 API Suppliers
3 CEP/COS
2 EU WC
4 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

2 FDF Dossiers, 2 Listed Dossiers

2 FDF Dossiers
2 Listed Dossiers

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1 DATA COMPILATION #PharmaFlow

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4 APIs, 2 FDF Dossiers

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4 APIs
2 FDF Dossiers

REF. STANDARDS & IMPURITIES

2 EDQM

otherSolutions
2 EDQM

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 199

MARKET PLACE

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FDF

0INTERMEDIATES

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FDA Orange Book

Europe

Canada

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0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

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PATENTS & EXCLUSIVITIES

US Patents

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Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

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US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

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0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 52214-84-3, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid, Lipanor, Ciprofibratum, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid, Ciprofibrato

Molecular Formula

C₁₃H₁₄Cl₂O₃

Molecular Weight

289.15 g/mol

InChI Key

KPSRODZRAIWAKH-UHFFFAOYSA-N

FDA UNII

F8252JGO9S

Ciprofibrate is a fibrate derivative with antilipidemic activity.

1 2D Structure

Ciprofibrate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

2.1.2 InChI

InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

2.1.3 InChI Key

KPSRODZRAIWAKH-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl

2.2 Other Identifiers

2.2.1 UNII

F8252JGO9S

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Hyperlipen

2. Lipanor

3. Modalim

4. Oroxadin

5. Win 35,833

2.3.2 Depositor-Supplied Synonyms

1. 52214-84-3

2. 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic Acid

3. Lipanor

4. Ciprofibratum

5. 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic Acid

6. Ciprofibrato

7. Modalim

8. Win 35833

9. Win-35833

10. Propanoic Acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-

11. Mfcd00467135

12. 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionic Acid

13. Nsc-759617

14. F8252jgo9s

15. Chebi:50867

16. Propanoic Acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-

17. Ncgc00164447-01

18. 2-{[4-(2,2-dichlorocyclopropyl)phenyl]oxy}-2-methylpropanoic Acid

19. Dsstox_cid_331

20. Dsstox_rid_75519

21. Dsstox_gsid_20331

22. Ciprofibratum [inn-latin]

23. Ciprofibrato [inn-spanish]

24. Hiperlipen

25. Ciprol

26. Smr000857190

27. Ccris 173

28. Sr-01000075734

29. Einecs 257-744-6

30. Ciprofibrate (usan/inn)

31. Brn 1984981

32. Unii-f8252jgo9s

33. 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid

34. Ciprofibrate?

35. Ciprofibrate [usan:inn:ban]

36. 2-(4-(2,2-dichlorocyclopropyl)phenoxy)2-methylpropanoic Acid

37. 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic Acid

38. Cas-52214-84-3

39. Ciprofibrate- Bio-x

40. Prestwick0_001076

41. Prestwick1_001076

42. Prestwick2_001076

43. Prestwick3_001076

44. Ciprofibrate [mi]

45. Ciprofibrate [inn]

46. C 0330

47. Ciprofibrate [usan]

48. Lopac0_000168

49. Schembl26870

50. Bspbio_001092

51. Ciprofibrate [mart.]

52. Mls002154143

53. Mls006011758

54. Ciprofibrate [who-dd]

55. Win35833

56. Spbio_002996

57. Bpbio1_001202

58. Chembl557555

59. Gtpl3438

60. Dtxsid8020331

61. Bcpp000277

62. Ciprofibrate [ep Impurity]

63. Ciprofibrate For System Suitability

64. Hms1571g14

65. Hms2098g14

66. Hms2235j14

67. Hms3260b17

68. Hms3369b22

69. Hms3656p09

70. Hms3715g14

71. Pharmakon1600-01502008

72. Ciprofibrate [ep Monograph]

73. Bcp03728

74. Hy-b0664

75. Tox21_112121

76. Tox21_201359

77. Tox21_302840

78. Tox21_500168

79. Bbl010821

80. Bdbm50371235

81. Nsc759617

82. S2665

83. Stk624758

84. Akos005557843

85. Tox21_112121_1

86. Ac-1018

87. Bcp9000533

88. Ccg-204263

89. Db09064

90. Ks-1201

91. Lp00168

92. Nsc 759617

93. Sdccgsbi-0050156.p002

94. Ncgc00015202-02

95. Ncgc00015202-03

96. Ncgc00015202-04

97. Ncgc00015202-05

98. Ncgc00015202-06

99. Ncgc00015202-08

100. Ncgc00015202-20

101. Ncgc00015202-21

102. Ncgc00093652-01

103. Ncgc00093652-02

104. Ncgc00256361-01

105. Ncgc00258911-01

106. Ncgc00260853-01

107. Bd164311

108. Bcp0726000148

109. Ab00514032

110. Eu-0100168

111. Ft-0602946

112. Sw197242-4

113. D03521

114. O10468

115. Ab00514032_06

116. 214c843

117. A828985

118. J-520054

119. Q3496452

120. Sr-01000075734-1

121. Sr-01000075734-4

122. Sr-01000075734-7

123. Brd-a49358627-001-03-9

124. Brd-a49358627-001-10-4

125. 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic Acid

126. Ciprofibrate, European Pharmacopoeia (ep) Reference Standard

127. 2-[4-[2,2-bis(chloranyl)cyclopropyl]phenoxy]-2-methyl-propanoic Acid

128. Ciprofibrate For System Suitability, European Pharmacopoeia (ep) Reference Standard

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₃H₁₄Cl₂O₃
Molecular Weight	289.15 g/mol
XLogP3	3.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	288.0319997 g/mol
Monoisotopic Mass	288.0319997 g/mol
Topological Polar Surface Area	46.5 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	333
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Peroxisome Proliferators

A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration. (See all compounds classified as Peroxisome Proliferators.)

Hypolipidemic Agents

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)

4.2 ATC Code

C10AB08

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

C - Cardiovascular system

C10 - Lipid modifying agents

C10A - Lipid modifying agents, plain

C10AB - Fibrates

C10AB08 - Ciprofibrate

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API Reference Price

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