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Chemistry

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Also known as:
Molecular Formula
C20H28N12O9PPt+
Molecular Weight
806.6  g/mol
InChI Key
BWNPJEJDQASSEO-UHFFFAOYSA-M

Cisplatin
1 2D Structure

Cisplatin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] phosphate;azanide;platinum(4+)
2.1.2 InChI
InChI=1S/C20H25N10O9P.2H2N.Pt/c21-16-14-17(24-5-23-16)29(6-25-14)13-2-9(10(3-31)37-13)39-40(34,35)36-4-11-8(32)1-12(38-11)30-7-26-15-18(30)27-20(22)28-19(15)33;;;/h5-13,31-32H,1-4H2,(H,34,35)(H2,21,23,24)(H3,22,27,28,33);2*1H2;/q;2*-1;+4/p-1
2.1.3 InChI Key
BWNPJEJDQASSEO-UHFFFAOYSA-M
2.1.4 Canonical SMILES
C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)([O-])OC4CC(OC4CO)N5C=NC6=C(N=CN=C65)N)O.[NH2-].[NH2-].[Pt+4]
2.1.5 Isomeric SMILES
C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)([O-])OC4CC(OC4CO)N5C=NC6=C(N=CN=C65)N)O.[NH2-].[NH2-].[Pt+4]
2.2 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 806.6 g/mol
Molecular Formula C20H28N12O9PPt+
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count16
Rotatable Bond Count1
Exact Mass806.148777 g/mol
Monoisotopic Mass806.148777 g/mol
Topological Polar Surface Area274 A^2
Heavy Atom Count43
Formal Charge1
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count6
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count4

API Reference Price

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HIGHWAY, THALTEJ","city":"AHMEDABAD,GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.06","actualQuantity":"57","unit":"GMS","unitRateFc":"26.1","totalValueFC":"1487.8","currency":"USD","unitRateINR":"2147.8","date":"12-Oct-2022","totalValueINR":"122425.88","totalValueInUsd":"1487.8","indian_port":"AHMEDABAD AIR","hs_no":"29420090","bill_no":"2837036","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665513000,"product":"CHEMICAL : CISPLATIN EP","address":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ","city":"AHMEDABAD,GUJARAT","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"INTAS PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.07","actualQuantity":"65","unit":"GMS","unitRateFc":"26.1","totalValueFC":"1696.7","currency":"USD","unitRateINR":"2147.8","date":"12-Oct-2022","totalValueINR":"139608.46","totalValueInUsd":"1696.7","indian_port":"AHMEDABAD AIR","hs_no":"29420090","bill_no":"2837036","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. HIGHWAY, THALTEJ"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1665513000,"product":"CHEMICAL : CISPLATIN EP","address":"CORPORATE HOUSE, NR. SOLA BRIDGE,, S.G. 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SOLA BRIDGE,,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1679337000,"product":"CISPLATIN EP\/USP BATCH NO. 201230020 (2345GMS) 202230020 (2370 GMS) 203230020 (285GMS)","address":"B-310, SOM DATT CHAMBERS, 1,,BHIKA JI CAMA PLACE,","city":"NEW DELHI,DELHI","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"FRESENIUS SE & CO. KGAA","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5000","unit":"GMS","unitRateFc":"30.5","totalValueFC":"155187.8","currency":"USD","unitRateINR":"2552.9","date":"21-Mar-2023","totalValueINR":"12764250","totalValueInUsd":"155187.8","indian_port":"DELHI AIR","hs_no":"29146990","bill_no":"5152235","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B-310, SOM DATT CHAMBERS, 1,,BHIKA JI CAMA PLACE,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1680287400,"product":"CISPLATIN API (10 GRAM) (CISPLATIN) (SAMPLE OF NCV)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"GLENMARK PHARMACEUTICALS","supplierCountry":"ARGENTINA","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"0.01","unit":"KGS","unitRateFc":"31450","totalValueFC":"362.2","currency":"USD","unitRateINR":"2968681","date":"01-Apr-2023","totalValueINR":"29686.81","totalValueInUsd":"362.2","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"5336003","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688409000,"product":"CISPLATIN","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"FRANKFURT AM MAIN","customer":"GLAND PHARMA LIMITED","customerCountry":"INDIA","quantity":"2.27","actualQuantity":"2265","unit":"GMS","unitRateFc":"31.8","totalValueFC":"72666.6","currency":"USD","unitRateINR":"2636.8","date":"04-Jul-2023","totalValueINR":"5972437","totalValueInUsd":"72666.6","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29339990","bill_no":"1001224","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT AM MAIN","supplierAddress":"10 REUTEN DRIVE CLOSTER NJ 07624 UNITED STATES","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1696012200,"product":"CISPLATIN EP\/USP CAS#15663-27-1 B\/N. 234230020 MFG DT. 28.7.23 EXP DT.27.7.2027B\/N 235230020 MFG DT.31.7.23 EXPDT30.7.27","address":"B-310, SOM DATT CHAMBERS, 1,","city":"NEW DELHI","supplier":"FLAVIN NORTH AMERICA, INC.","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"FRESENIUS SE & CO. 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15-Mar-2021
18-Sep-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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Europe

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01

Accord Healthcare Ltd.

United Kingdom
Antibody Engineering
Not Confirmed
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Accord Healthcare Ltd.

United Kingdom
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Antibody Engineering
Not Confirmed

Cisplatin

Brand Name : Cisplatin Accord

Dosage Form : Concentrate to the infusion fluid, resolution

Dosage Strength : 1 mg/ml

Packaging : Hood glass

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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02

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

cisplatin

Brand Name : Cisplatin Hospira

Dosage Form : CONCENTRATE FOR SOLUTION FOR INFUSION

Dosage Strength : 1 MG / ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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03

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Cisplatin

Brand Name : Cisplatin

Dosage Form : Cisplatin 50Mg 50Ml 1 Units Parenteral Use

Dosage Strength : 1 vial EV 50 mg 50 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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04

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Cisplatin

Brand Name : Cisplatin Hospira

Dosage Form : Concentrate to the infusion fluid

Dosage Strength : 1 mg/ml

Packaging : Hood glass of dark glass with plastic Sheaths

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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05

Antibody Engineering
Not Confirmed
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arrow
Antibody Engineering
Not Confirmed

Cisplatin

Brand Name : Cisplatin Hospira

Dosage Form : Concentrate to the infusion fluid

Dosage Strength : 1 mg/ml

Packaging : Hood glass of dark glass with plastic Sheaths

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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06

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Cisplatinum

Brand Name : Cisplatin Sandoz

Dosage Form : Inf Conc

Dosage Strength : 100mg/100ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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07

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Cisplatinum

Brand Name : Cisplatin Sandoz

Dosage Form : Inf Conc

Dosage Strength : 10mg/20ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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08

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Cisplatinum

Brand Name : Cisplatin Sandoz

Dosage Form : Inf Conc

Dosage Strength : 25mg/50ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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09

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

Cisplatin

Brand Name : Cisplatin

Dosage Form : Cisplatin 10Mg 20Ml 1 Units Parenteral Use

Dosage Strength : 1 vial EV 10 mg 20 ml

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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10

Antibody Engineering
Not Confirmed
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Antibody Engineering
Not Confirmed

cisplatin

Brand Name : Cisplatin Mylan

Dosage Form : CONCENTRATE FOR SOLUTION FOR INFUSION

Dosage Strength : 1 MG / ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - 0.5MG/ML

USFDA APPLICATION NUMBER - 18057

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DOSAGE - INJECTABLE;INJECTION - 10MG/VIAL

USFDA APPLICATION NUMBER - 18057

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DOSAGE - INJECTABLE;INJECTION - 1MG/ML

USFDA APPLICATION NUMBER - 18057

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DOSAGE - INJECTABLE;INJECTION - 50MG/VIAL

USFDA APPLICATION NUMBER - 18057

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Direct Compression

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Co-Processed Excipients

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Granulation

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Disintegrants & Superdisintegrants

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API Stability Enhancers

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