Find Clinafloxacin manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 105956-97-6, 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Clinafloxacin [inn], Ci-960, 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid, Am-1091
Molecular Formula
C17H17ClFN3O3
Molecular Weight
365.8  g/mol
InChI Key
QGPKADBNRMWEQR-UHFFFAOYSA-N
FDA UNII
8N86XTF9QD

Clinafloxacin
Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of serious side effects.
1 2D Structure

Clinafloxacin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid
2.1.2 InChI
InChI=1S/C17H17ClFN3O3/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9/h5,7-9H,1-4,6,20H2,(H,24,25)
2.1.3 InChI Key
QGPKADBNRMWEQR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)Cl)N4CCC(C4)N)F)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
8N86XTF9QD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid

2. Am 1091

3. Am-1091

4. Ci 960

5. Ci-960

6. Pd 127,391

7. Pd 127391

8. Pd-127,391

9. Pd-127391

10. Pd127,391

2.3.2 Depositor-Supplied Synonyms

1. 105956-97-6

2. 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

3. Clinafloxacin [inn]

4. Ci-960

5. 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic Acid

6. Am-1091

7. 8n86xtf9qd

8. Clinafloxacin (hydrochloride)

9. 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid

10. Am-1091;ci-960;pd 127391

11. Am 1091 (hydrochloride); Ci 960 (hydrochloride);pd127391 (hydrochloride)

12. 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-quinoline-3-carboxylic Acid

13. Clinafloxacin Ci96 Am1091

14. Unii-8n86xtf9qd

15. Pd 127321

16. Am 1091

17. Pd 127391

18. Pd-127391

19. Clinafloxacin [mi]

20. Bay-v-3545

21. Schembl33959

22. 3-quinolinecarboxylic Acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-

23. Mls000778572

24. Clinafloxacin (pd127391)

25. Clinafloxacin [who-dd]

26. Chembl278255

27. Chebi:94459

28. Gtpl10793

29. Dtxsid80869455

30. Hms2090o15

31. Hms2770f24

32. Hms3714j19

33. Amy28813

34. Bcp21182

35. Hy-b0536

36. Rkl10079

37. Am1091

38. Bbl010979

39. Bdbm50474311

40. Mfcd00865120

41. S4006

42. Stk802100

43. Akos005622667

44. Ccg-220849

45. Db14025

46. Ncgc00246499-01

47. Ac-32467

48. Pd127391

49. Smr000415366

50. Vs-02785

51. Db-040667

52. Pd-127321

53. Ft-0602938

54. 56c976

55. Ab00647129-10

56. Ab00647129_11

57. Ab00647129_13

58. Ab00647129_14

59. A801341

60. A801342

61. Clinafloxacin, Vetranal(tm), Analytical Standard

62. Sr-01000765993

63. J-001508

64. Q3680752

65. Sr-01000765993-2

66. Brd-a93964801-003-01-7

67. 7-(3-azaniumylpyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylate

68. (+/-)-7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid

69. 3-quinolinecarboxylic Acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, (+/-)-

70. 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid, Monohydrochloride

71. 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylicacid

72. 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

73. 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylic Acid

74. 7-(3-amino-pyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic Acid

75. 7-(3-amino-pyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic Acid

76. 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-quinoline-3-carboxylic Acid;clinafloxacin

77. 7-(3-azanylpyrrolidin-1-yl)-8-chloranyl-1-cyclopropyl-6-fluoranyl-4-oxidanylidene-quinoline-3-carboxylic Acid

2.4 Create Date
2005-07-19
3 Chemical and Physical Properties
Molecular Weight 365.8 g/mol
Molecular Formula C17H17ClFN3O3
XLogP30.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass365.0942473 g/mol
Monoisotopic Mass365.0942473 g/mol
Topological Polar Surface Area86.9 Ų
Heavy Atom Count25
Formal Charge0
Complexity626
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


Topoisomerase II Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)


ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty