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    Chemistry

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    Also known as: 24729-96-2, Cleocin phosphate, Clindamycin 2-phosphate, Clindets, Cleocin t, Clindagel
    Molecular Formula
    C18H34ClN2O8PS
    Molecular Weight
    505.0  g/mol
    InChI Key
    UFUVLHLTWXBHGZ-MGZQPHGTSA-N
    FDA UNII
    EH6D7113I8
    Clindamycin Phosphate
    Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate is used in topical preparations.
    1 2D Structure

    Clindamycin Phosphate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-[[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] dihydrogen phosphate
    2.1.2 InChI
    InChI=1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1
    2.1.3 InChI Key
    UFUVLHLTWXBHGZ-MGZQPHGTSA-N
    2.1.4 Canonical SMILES
    CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)OP(=O)(O)O)O)O)C(C)Cl
    2.1.5 Isomeric SMILES
    CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)OP(=O)(O)O)O)O)[C@H](C)Cl
    2.2 Other Identifiers
    2.2.1 UNII
    EH6D7113I8
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Cleocin Phosphate

    2. Clindamycin-2-phosphate

    3. Clindesse

    4. Clindets

    2.3.2 Depositor-Supplied Synonyms

    1. 24729-96-2

    2. Cleocin Phosphate

    3. Clindamycin 2-phosphate

    4. Clindets

    5. Cleocin T

    6. Clindagel

    7. Clindesse

    8. Evoclin

    9. Clinda-derm

    10. Dalacin P

    11. Clindamycin-2-phosphate

    12. Clindamycin 2-dihydrogen Phosphate

    13. Clindamycin (phosphate)

    14. Dalacin T

    15. 7(s)-chloro-7-deoxylincomycin 2-phosphate

    16. U 28508

    17. U-28508

    18. U-28,508

    19. Eh6d7113i8

    20. Nsc 618653

    21. Nsc-618653

    22. Dsstox_cid_28603

    23. Dsstox_rid_82873

    24. Dsstox_gsid_48677

    25. [(2r,3r,4s,5r,6r)-6-[(1s,2s)-2-chloro-1-[[(2s,4r)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] Dihydrogen Phosphate

    26. Clindamax

    27. Evoclin (tn)

    28. Dalacin-s (tn)

    29. Clindamycin Injection

    30. Cas-24729-96-2

    31. Einecs 246-433-0

    32. Clindamycin Phosphate Hydrate [jan]

    33. Clindamycin Dihydrogenphosphat

    34. Clinadac

    35. Unii-eh6d7113i8

    36. Clindamycin Phosphate Hydrate

    37. Clindamycin Phosphate In Dextrose 5%

    38. Clindamycin-2-dihydrogenphosphat

    39. Ncgc00163494-01

    40. Ncgc00166320-01

    41. Clindamycin-phosphate

    42. Clindac

    43. Xaciato

    44. Clindamycin Phosphate [usan:usp:jan]

    45. Cleocin Phosphate In Dextrose 5% In Plastic Container

    46. Clindamycin Phosphate In Dextrose 5% In Plastic Container

    47. Schembl37148

    48. Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-l-threo-alpha-d-galacto-octopyranoside 2-(dihydrogen Phosphate)

    49. Chembl3184512

    50. Dtxsid1048677

    51. Bdbm241975

    52. Clindamycin (as Phosphate)

    53. Clindamycin Phosphate (jp17/usp)

    54. Clindamycin Phosphate [jan]

    55. Hy-b1064

    56. Zinc4102185

    57. Clindamycin Phosphate [usan]

    58. Tox21_113055

    59. Tox21_113410

    60. Clindamycin Phosphate (u-28508e)

    61. Clindamycin Phosphate [vandf]

    62. Mfcd11982855

    63. S2048

    64. Clindamycin Phosphate [mart.]

    65. Akos008901431

    66. Clindamycin Phosphate [usp-rs]

    67. Clindamycin Phosphate [who-dd]

    68. Clindamycin Phosphate [who-ip]

    69. Ccg-269736

    70. Clindamycin Phosphate System Suitability

    71. Cs-4620

    72. Ncgc00386379-01

    73. As-12554

    74. L-threo-alpha-d-galacto-octapyranoside, Methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, 2-(dihydrogen Phosphate), (2s-trans)-

    75. Methyl (2s-trans)-7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-l-threo-alpha-d-galacto-octopyranoside, 2-(dihydrogen Phosphate)

    76. Clindamycin Phosphate [orange Book]

    77. Duac Component Clindamycin Phosphate

    78. Clindamycin Phosphate [ep Monograph]

    79. Clindamycin Phosphate For System Suitability

    80. Ziana Component Clindamycin Phosphate

    81. Acanya Component Clindamycin Phosphate

    82. Clindamycin Phosphate [usp Monograph]

    83. Clindamycini Phosphas [who-ip Latin]

    84. Veltin Component Clindamycin Phosphate

    85. Clindamycin Phosphate Component Of Duac

    86. Benzaclin Component Clindamycin Phosphate

    87. Clindamycin 2-dihydrogen Phosphate [mi]

    88. Clindamycin Phosphate Component Of Ziana

    89. D01073

    90. Idp-126 Component Clindamycin Phosphate

    91. Ab01566857_01

    92. Clindamycin Phosphate Component Of Acanya

    93. Clindamycin Phosphate Component Of Veltin

    94. A817470

    95. Clindamycin Phosphate Component Of Benzaclin

    96. Sr-01000872581

    97. Sr-01000872581-1

    98. Brd-k27771035-001-02-5

    99. Q27106184

    100. Clindamycin Phosphate System Suitability [usp-rs]

    101. (2r,3r,4s,5r,6r)-6-((1s,2s)-2-chloro-1-((2s,4r)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-4,5-dihydroxy-2-(methylthio)tetrahydro-2h-pyran-3-yl Dihydrogen Phosphate

    102. (2r,3r,4s,5r,6r)-6-((1s,2s)-2-chloro-1-((2s,4r)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-4,5-dihydroxy-2-(methylthio)tetrahydro-2h-pyran-3-yldihydrogenphosphate

    103. (2s-trans)-methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-l-threo-.alpha.-d-galacto-octopyranoside 2-(dihydrogen Phosphate)

    104. [(2r,3r,4s,5r,6r)-6-[(1s,2s)-2-chloro-1-[[(2s,4r)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] Dihydrogen Phosphate

    105. [(2r,4r,5r)-6-[(2s)-2-chloro-1-[[[(2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl]-oxomethyl]amino]propyl]-4,5-dihydroxy-2-(methylthio)-3-oxanyl] Dihydrogen Phosphate

    106. L-threo-.alpha.-d-galacto-octopyranoside, Methyl 7-chloro-6,7,8-trideoxy-6-((((2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, 2-(dihydrogen Phosphate)

    107. L-threo-.alpha.-d-galacto-octopyranoside, Methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, 2-(dihydrogen Phosphate), (2s-trans)-

    108. Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-l-threo-.alpha.-d-galacto-octopyranoside 2-(dihydrogen Phosphate)

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 505.0 g/mol
    Molecular Formula C18H34ClN2O8PS
    XLogP3-1.2
    Hydrogen Bond Donor Count5
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count9
    Exact Mass504.1462019 g/mol
    Monoisotopic Mass504.1462019 g/mol
    Topological Polar Surface Area174 Ų
    Heavy Atom Count31
    Formal Charge0
    Complexity658
    Isotope Atom Count0
    Defined Atom Stereocenter Count9
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 12  
    Drug NameCleocin phosphate
    Drug LabelCLEOCIN PHOSPHATE Sterile Solution in vials contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as p...
    Active IngredientClindamycin phosphate
    Dosage FormInjectable
    RouteInjection
    Strengtheq 150mg base/ml
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    2 of 12  
    Drug NameCleocin t
    Active IngredientClindamycin phosphate
    Dosage FormGel; Lotion; Solution
    RouteTopical
    Strengtheq 1% base
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    3 of 12  
    Drug NameClindagel
    Drug LabelClindagel (clindamycin phosphate gel) topical gel, 1%, a topical antibiotic, contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 941, methylparaben, polyethylene g...
    Active IngredientClindamycin phosphate
    Dosage FormGel
    RouteTopical
    Strengtheq 1% base
    Market StatusPrescription
    CompanyPrecision Dermat

    4 of 12  
    Drug NameClindamycin phosphate
    PubMed HealthClindamycin (Injection)
    Drug ClassesAntibiotic, Antimalarial
    Drug LabelClindamycin Injection, USP, a water soluble ester of clindamycin and phosphoric acid, is a sterile solution for intramuscular or intravenous use.May contain sodium hydroxide and/or hydrochloric acid for pH adjustment. pH is 6.5 range 5.5to 7.0.Clin...
    Active IngredientClindamycin phosphate
    Dosage FormLotion; Gel; Swab; Injectable; Cream; Aerosol, foam; Solution
    RouteTopical; Injection; Vaginal
    Strengtheq 1% base; 1%; eq 150mg base/ml; eq 2% base
    Market StatusPrescription
    CompanyWockhardt; Sagent Strides; Bedford; Fougera Pharms; Fresenius Kabi Usa; Hospira; Hikma Maple; Versapharm; Perrigo Uk Finco; Perrigo New York; Taro Pharm Inds; Fougera; G And W Labs

    5 of 12  
    Drug NameClindesse
    Drug LabelCLEOCIN T Topical Solution and CLEOCIN T Topical Lotion contain clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. CLEOCIN T Topical Gel contains clindamycin phosphate, USP, at a concentration equivalent to...
    Active IngredientClindamycin phosphate
    Dosage FormCream
    RouteVaginal
    Strengtheq 2% base
    Market StatusPrescription
    CompanyLumara Health

    6 of 12  
    Drug NameClindets
    Drug LabelClindamycin phosphate, a lincosamide, is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is meth...
    Active IngredientClindamycin phosphate
    Dosage FormSwab
    RouteTopical
    Strengtheq 1% base
    Market StatusPrescription
    CompanyPerrigo

    7 of 12  
    Drug NameCleocin phosphate
    Drug LabelCLEOCIN PHOSPHATE Sterile Solution in vials contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as p...
    Active IngredientClindamycin phosphate
    Dosage FormInjectable
    RouteInjection
    Strengtheq 150mg base/ml
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    8 of 12  
    Drug NameCleocin t
    Active IngredientClindamycin phosphate
    Dosage FormGel; Lotion; Solution
    RouteTopical
    Strengtheq 1% base
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    9 of 12  
    Drug NameClindagel
    Drug LabelClindagel (clindamycin phosphate gel) topical gel, 1%, a topical antibiotic, contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 941, methylparaben, polyethylene g...
    Active IngredientClindamycin phosphate
    Dosage FormGel
    RouteTopical
    Strengtheq 1% base
    Market StatusPrescription
    CompanyPrecision Dermat

    10 of 12  
    Drug NameClindamycin phosphate
    PubMed HealthClindamycin (Injection)
    Drug ClassesAntibiotic, Antimalarial
    Drug LabelClindamycin Injection, USP, a water soluble ester of clindamycin and phosphoric acid, is a sterile solution for intramuscular or intravenous use.May contain sodium hydroxide and/or hydrochloric acid for pH adjustment. pH is 6.5 range 5.5to 7.0.Clin...
    Active IngredientClindamycin phosphate
    Dosage FormLotion; Gel; Swab; Injectable; Cream; Aerosol, foam; Solution
    RouteTopical; Injection; Vaginal
    Strengtheq 1% base; 1%; eq 150mg base/ml; eq 2% base
    Market StatusPrescription
    CompanyWockhardt; Sagent Strides; Bedford; Fougera Pharms; Fresenius Kabi Usa; Hospira; Hikma Maple; Versapharm; Perrigo Uk Finco; Perrigo New York; Taro Pharm Inds; Fougera; G And W Labs

    11 of 12  
    Drug NameClindesse
    Drug LabelCLEOCIN T Topical Solution and CLEOCIN T Topical Lotion contain clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per milliliter. CLEOCIN T Topical Gel contains clindamycin phosphate, USP, at a concentration equivalent to...
    Active IngredientClindamycin phosphate
    Dosage FormCream
    RouteVaginal
    Strengtheq 2% base
    Market StatusPrescription
    CompanyLumara Health

    12 of 12  
    Drug NameClindets
    Drug LabelClindamycin phosphate, a lincosamide, is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. The chemical name for clindamycin phosphate is meth...
    Active IngredientClindamycin phosphate
    Dosage FormSwab
    RouteTopical
    Strengtheq 1% base
    Market StatusPrescription
    CompanyPerrigo

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Lincosamide Antibacterial [EPC]; Lincosamides [CS]; Neuromuscular Blockade [PE]; Decreased Sebaceous Gland Activity [PE]

    API Reference Price

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    16-Jan-2021
    31-Aug-2024
    KGS
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    Average Price (USD/KGS)

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    Total Quantity (KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

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    (USD/KGS)    		 Number of Transactions

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    DOSAGE - SOLUTION;INTRAVENOUS - EQ 300MG BASE...DOSAGE - SOLUTION;INTRAVENOUS - EQ 300MG BASE/50ML (EQ 6MG BASE/ML)

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    Clindamycin Phosphate Manufacturers | Traders | Suppliers

    Clindamycin Phosphate Manufacturers, Traders, Suppliers 1
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    We have 5 companies offering Clindamycin Phosphate

    Get in contact with the supplier of your choice:

    1. Chongqing Carelife Pharmaceutical
    2. Suzhou no. 4 Pharmaceutical Factory
    3. Trifarma
    4. UQUIFA
    5. Zhejiang Hisoar Pharmaceutical
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