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Chemistry

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Also known as: 2971-90-6, 3,5-dichloro-2,6-dimethylpyridin-4-ol, Meticlorpindol, Coyden, Lerbek, Coccidiostat c
Molecular Formula
C7H7Cl2NO
Molecular Weight
192.04  g/mol
InChI Key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
FDA UNII
8J763HFF5N

Clopidol
A very effective anticoccidial agent used in poultry.
1 2D Structure

Clopidol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3,5-dichloro-2,6-dimethyl-1H-pyridin-4-one
2.1.2 InChI
InChI=1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
2.1.3 InChI Key
ZDPIZLCVJAAHHR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=O)C(=C(N1)C)Cl)Cl
2.2 Other Identifiers
2.2.1 UNII
8J763HFF5N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3,5-dichloro-2,6-dimethyl-4-pyridinol

2. Clopindol

3. Meticlorpindol

2.3.2 Depositor-Supplied Synonyms

1. 2971-90-6

2. 3,5-dichloro-2,6-dimethylpyridin-4-ol

3. Meticlorpindol

4. Coyden

5. Lerbek

6. Coccidiostat C

7. Metichlorpindol

8. Methylchlorpindol

9. Methylchloropindol

10. 4-pyridinol, 3,5-dichloro-2,6-dimethyl-

11. Clopindol

12. Coyden 25

13. 3,5-dichloro-2,6-dimethyl-4-pyridinol

14. Rigekokcin (rigecoccin)

15. 3,5-dichloro-2,6-dimethyl-1h-pyridin-4-one

16. 2,6-dimethyl-3,5-dichloro-4-pyridinol

17. Nsc 253479

18. 3,5-dichloro-4-hydroxy-2,6-dimethylpyridine

19. Brn 1527826

20. Nsc-253479

21. 8j763hff5n

22. 3,5-dichloro-2,6-dimethylpyridin-4(1h)-one

23. Ncgc00095166-01

24. 3,5-dichloro-2,6-dimethyl-4-hydroxypyridine

25. Clopidol 100 Microg/ml In Acetonitrile/methanol

26. Dsstox_cid_21793

27. Dsstox_rid_79844

28. Dsstox_gsid_41793

29. Clopidolo [dcit]

30. Clopidolum

31. Farmcoccid

32. Pharmcoccid

33. Pharmcoccide

34. Clopidolo

35. Caswell No. 306aa

36. Clopidolum [inn-latin]

37. Clopidol [usan:inn:ban]

38. Cas-2971-90-6

39. Einecs 221-008-2

40. Epa Pesticide Chemical Code 306200

41. Unii-8j763hff5n

42. Hsdb 7907

43. 3,6-dimethylpyridine

44. Clopidol [usan]

45. Clopidol (usan/inn)

46. Clopidol [inn]

47. Clopidol [mi]

48. Spectrum2_000018

49. Spectrum3_001952

50. Clopidol [mart.]

51. 3,6-dimethyl-4-pyridinol

52. Bspbio_003552

53. Clopidol [green Book]

54. Schembl661598

55. Spectrum1505319

56. Spbio_000055

57. Chembl446918

58. Dtxsid8041793

59. Schembl11480048

60. Kbio3_002866

61. Chebi:183853

62. Hms1922d10

63. Hms2090o19

64. Hms2093b15

65. Pharmakon1600-01505319

66. Hy-b1088

67. Zinc8830661

68. Tox21_111465

69. 3,5-dichloro-2,6-dimethylpyridinol

70. Bbl011029

71. Ccg-40048

72. Clopidol 100 Microg/ml In Methanol

73. Mfcd00867211

74. Nsc253479

75. Nsc758964

76. S4142

77. Stk802181

78. Stl032651

79. Akos005622703

80. Akos005642292

81. Tox21_111465_1

82. Cs-4655

83. Ks-1254

84. Nsc-758964

85. 4-pyridinol,5-dichloro-2,6-dimethyl-

86. Clopidol 100 Microg/ml In Acetonitrile

87. Ncgc00095166-02

88. Ncgc00095166-03

89. Ncgc00095166-04

90. Ac-24199

91. Wr-61112

92. 3,5-dichloro-2,6-dimethyl-pyridin-4-ol

93. Sbi-0206752.p001

94. Db-047634

95. Ft-0603199

96. Clopidol, Vetranal(tm), Analytical Standard

97. A16464

98. D03559

99. Ab01563058_01

100. 971c906

101. 971d906

102. A820023

103. Sr-05000002003

104. J-017612

105. Q5135111

106. Sr-05000002003-1

107. Brd-k80036624-001-03-2

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 192.04 g/mol
Molecular Formula C7H7Cl2NO
XLogP32.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass190.9904692 g/mol
Monoisotopic Mass190.9904692 g/mol
Topological Polar Surface Area29.1 Ų
Heavy Atom Count11
Formal Charge0
Complexity252
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Therapeutic Uses

THERAPEUTIC CATEGORY (VETERINARY): Coccidiostat

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 403


Used as an anticoccidiostat in poultry.

American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-4148 2010.


Clopidol is mainly coccidiostatic and is active only against the sporozoite stage of Eimeria.

Sams R; Ullmann's Encyclopedia of Industrial Chemistry 7th ed. (2010). NY, NY: John Wiley & Sons; Veterinary Drugs. Online Posting Date: June 15, 2000


MEDICATION (VET): Turkeys grown for meat purposes only: As an aid in the prevention of leucocytozoonosis caused by Leucocytozoon smithi.

US Natl Inst Health; DailyMed. Current Medication Information for COYDEN (clopidol) powder (March 2010). Available from, as of March 8, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=16475&CFID=55487510&CFTOKEN=245e1f8f4d81dce0-5FF4B3EE-CC3A-992F-5E755E9D27611217&jsessionid=ca3047782f012955657f


MEDICATION (VET): Broiler and replacement chickens: As an aid in the prevention of coccidiosis in broilers and replacements for caged layers caused by E. tenella, Eimeria necatrix, Eimeria Acervulina, Eimeria maxima, Eimeria brunetti, Eimeria mivati.

US Natl Inst Health; DailyMed. Current Medication Information for COYDEN (clopidol) powder (March 2010). Available from, as of March 8, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=16475&CFID=55487510&CFTOKEN=245e1f8f4d81dce0-5FF4B3EE-CC3A-992F-5E755E9D27611217&jsessionid=ca3047782f012955657f


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Coccidiostats

Agents useful in the treatment or prevention of COCCIDIOSIS in man or animals. (See all compounds classified as Coccidiostats.)


API Reference Price

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21-Jan-2021
26-Nov-2024
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INTERMEDIATES SUPPLIERS

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01

Inabata

France
Pharma, Lab & Chemical Expo
Not Confirmed
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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothIKF/Pharmasynthese have been with fine chemicals market and APIs performance for more than 40 years.

CAS Number : 108-48-5

End Use API : Clopidol

About The Company : Established in 1990, Inabata France, a part of the Inabata Group, used to export chemical and pharmaceutical products to Japan. In 2006, it acquired Pharmasynth...

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ABOUT THIS PAGE

Clopidol Manufacturers

A Clopidol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Clopidol, including repackagers and relabelers. The FDA regulates Clopidol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Clopidol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Clopidol Suppliers

A Clopidol supplier is an individual or a company that provides Clopidol active pharmaceutical ingredient (API) or Clopidol finished formulations upon request. The Clopidol suppliers may include Clopidol API manufacturers, exporters, distributors and traders.

Clopidol NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Clopidol as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Clopidol API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Clopidol as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Clopidol and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Clopidol NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Clopidol suppliers with NDC on PharmaCompass.

Clopidol GMP

Clopidol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Clopidol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Clopidol GMP manufacturer or Clopidol GMP API supplier for your needs.

Clopidol CoA

A Clopidol CoA (Certificate of Analysis) is a formal document that attests to Clopidol's compliance with Clopidol specifications and serves as a tool for batch-level quality control.

Clopidol CoA mostly includes findings from lab analyses of a specific batch. For each Clopidol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Clopidol may be tested according to a variety of international standards, such as European Pharmacopoeia (Clopidol EP), Clopidol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Clopidol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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