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Clorgyline

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ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF

1 API Suppliers
1 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

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GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Clorgyline, 17780-72-2, Chlorgyline, Clorgilinum, Clorgilina, M and b 9302

Molecular Formula

C₁₃H₁₅Cl₂NO

Molecular Weight

272.17 g/mol

InChI Key

BTFHLQRNAMSNLC-UHFFFAOYSA-N

FDA UNII

LYJ16FZU9Q

An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.

1 2D Structure

Clorgyline

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine

2.1.2 InChI

InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3

2.1.3 InChI Key

BTFHLQRNAMSNLC-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C

2.2 Other Identifiers

2.2.1 UNII

LYJ16FZU9Q

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Chlorgyline

2. Clorgilin

3. Clorgyline

2.3.2 Depositor-Supplied Synonyms

1. Clorgyline

2. 17780-72-2

3. Chlorgyline

4. Clorgilinum

5. Clorgilina

6. M And B 9302

7. Clorgiline [inn]

8. M & B 9302

9. N-methyl-n-propargyl-3-(2,4-dichlorophenoxy)propylamine

10. N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-2-propynylamine

11. M&b 9302

12. Clorgiline (inn)

13. Lyj16fzu9q

14. N-(3-(2,4-dichlorophenoxy)propyl)-n-methylprop-2-yn-1-amine

15. Chembl8706

16. Chebi:3763

17. N-[3-(2,4-dichlorophenoxy)propyl]-n-methylprop-2-yn-1-amine

18. 2-propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-

19. 2-propynylamine, N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-

20. Clorgilinum [inn-latin]

21. Clorgilina [inn-spanish]

22. 2-propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-n-methyl- (9ci)

23. Unii-lyj16fzu9q

24. Cas-17780-75-5

25. Brn 1976758

26. 2-propyn-1-amine, N-[3-(2,4-dichlorophenoxy)propyl]-n-methyl-, Hydrochloride

27. 3-(2,4-dichlorophenoxy)-n-methyl-n-prop-2-ynylpropan-1-amine

28. Clorgiline [inn:ban]

29. Prestwick0_000344

30. Prestwick1_000344

31. Prestwick2_000344

32. Prestwick3_000344

33. Lopac-m-3778

34. Lopac0_000746

35. Schembl61914

36. Bspbio_000407

37. Us8633208, Clorgyline

38. Spbio_002328

39. Bpbio1_000449

40. Gtpl6636

41. Dtxsid3048445

42. Bdbm15581

43. Zinc22200090

44. Ccg-204831

45. Db04017

46. Sdccgsbi-0050724.p003

47. Ncgc00015669-01

48. Ncgc00015669-02

49. Ncgc00015669-03

50. Ncgc00015669-04

51. Ncgc00015669-11

52. Ncgc00162235-01

53. M&b-9302

54. Sbi-0050724.p002

55. A20772

56. D03248

57. L001342

58. Q2889652

59. Brd-k73251053-003-03-2

60. Brd-k73251053-003-13-1

61. [3-(2,4-dichloro-phenoxy)-propyl]-methyl-prop-2-ynyl-amine

62. [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine

63. N-[3-(2,4-dichlorophenoxy)propyl]-n-methyl-prop-2-yn-1-amine

64. 3-(2,4-dichlorophenoxy)-n-methyl-n-prop-2-ynyl-propan-1-amine

65. N-[(2,6-dichloro-4-methyl-3-pyridyl)carbonyl]-n-(3,4-dichlorophenyl)urea

66. Clg

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₃H₁₅Cl₂NO
Molecular Weight	272.17 g/mol
XLogP3	4.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	271.0530695 g/mol
Monoisotopic Mass	271.0530695 g/mol
Topological Polar Surface Area	12.5 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	263
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antidepressive Agents

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

Monoamine Oxidase Inhibitors

A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)

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ABOUT THIS PAGE

Clorgyline Manufacturers

A Clorgyline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Clorgyline, including repackagers and relabelers. The FDA regulates Clorgyline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Clorgyline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Clorgyline Suppliers

A Clorgyline supplier is an individual or a company that provides Clorgyline active pharmaceutical ingredient (API) or Clorgyline finished formulations upon request. The Clorgyline suppliers may include Clorgyline API manufacturers, exporters, distributors and traders.

click here to find a list of Clorgyline suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Clorgyline USDMF

A Clorgyline DMF (Drug Master File) is a document detailing the whole manufacturing process of Clorgyline active pharmaceutical ingredient (API) in detail. Different forms of Clorgyline DMFs exist exist since differing nations have different regulations, such as Clorgyline USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Clorgyline DMF submitted to regulatory agencies in the US is known as a USDMF. Clorgyline USDMF includes data on Clorgyline's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Clorgyline USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Clorgyline suppliers with USDMF on PharmaCompass.

Clorgyline GMP

Clorgyline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Clorgyline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Clorgyline GMP manufacturer or Clorgyline GMP API supplier for your needs.

Clorgyline CoA

A Clorgyline CoA (Certificate of Analysis) is a formal document that attests to Clorgyline's compliance with Clorgyline specifications and serves as a tool for batch-level quality control.

Clorgyline CoA mostly includes findings from lab analyses of a specific batch. For each Clorgyline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Clorgyline may be tested according to a variety of international standards, such as European Pharmacopoeia (Clorgyline EP), Clorgyline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Clorgyline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.