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1. Y 6047
2. Y-6047
3. Y6047
1. Rize
2. Trecalmo
3. Rizen
4. Tienor
5. Rise
6. 33671-46-4
7. Clotiazepamum [inn-latin]
8. Y 6047
9. 5-(2-chlorophenyl)-7-ethyl-1-methyl-3h-thieno[2,3-e][1,4]diazepin-2-one
10. 5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2h-thieno(2,3-e)-1,4-diazepin-2-one
11. 5-(2-chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2h-thieno(2,3-e)(1,4)diazepin-2-one
12. Zcn055599v
13. 2h-thieno(2,3e)(1,4)-diazepin-2-one, 5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
14. 5-(2-chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2h-thieno[2,3-e][1,4]diazepin-2-one
15. Clotiazepamum
16. Distensan
17. Veratran
18. Clozan
19. Clotiazepam [inn:jan]
20. 2h-thieno(2,3-e)(1,4)diazepin-2-one, 1,3-dihydro-5-(o-chlorophenyl)-7-ethyl-1-methyl-
21. 2h-thieno[2,3-e]-1,4-diazepin-2-one, 5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
22. Rize (tn)
23. Einecs 251-627-3
24. Brn 0623332
25. Unii-zcn055599v
26. Dea No. 2752
27. Y-6047
28. Clotiazepam [mi]
29. Clotiazepam [inn]
30. Clotiazepam [jan]
31. Clotiazepam (jp17/inn)
32. Clotiazepam [mart.]
33. Schembl44592
34. Clotiazepam [who-dd]
35. Zinc1207
36. Chembl1697737
37. Dtxsid0022852
38. Chebi:31425
39. Hy-u00317
40. Akos005065735
41. Cs-7319
42. Db01559
43. D01328
44. Q2263999
45. 2h-thieno[2,3-e]-1,4-diazepine-2-one, 5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
46. 5-(2-chlorophenyl)-7-ethyl-1-methyl-1h,2h,3h-thieno[2,3-e][1,4]diazepin-2-one
| Molecular Weight | 318.8 g/mol |
|---|---|
| Molecular Formula | C16H15ClN2OS |
| XLogP3 | 3.5 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 318.0593620 g/mol |
| Monoisotopic Mass | 318.0593620 g/mol |
| Topological Polar Surface Area | 60.9 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 442 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For the treatment of anxiety disorders.
Clotiazepam is a thienodiazepine possessing anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It increases the stage 2 non-rapid eye movement sleep.
N05BA21
S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355
N - Nervous system
N05 - Psycholeptics
N05B - Anxiolytics
N05BA - Benzodiazepine derivatives
N05BA21 - Clotiazepam
Hepatic.
Clotiazepam has known human metabolites that include Hydroxy-clotiazepam and desmethyl-clotiazepam.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
4 hours
Clotiazepam acts at the benzodiazepine receptors (BZD). This agonizes the action of GABA, increasing the frequency of opening of the channel chlorinates and penetration of the ions chlorinates through the ionophore. Increase in membrane polarization decreases the probability of discharge of neurons.
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A Clotiazepam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Clotiazepam, including repackagers and relabelers. The FDA regulates Clotiazepam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Clotiazepam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Clotiazepam manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Clotiazepam supplier is an individual or a company that provides Clotiazepam active pharmaceutical ingredient (API) or Clotiazepam finished formulations upon request. The Clotiazepam suppliers may include Clotiazepam API manufacturers, exporters, distributors and traders.
click here to find a list of Clotiazepam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Clotiazepam written confirmation (Clotiazepam WC) is an official document issued by a regulatory agency to a Clotiazepam manufacturer, verifying that the manufacturing facility of a Clotiazepam active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Clotiazepam APIs or Clotiazepam finished pharmaceutical products to another nation, regulatory agencies frequently require a Clotiazepam WC (written confirmation) as part of the regulatory process.
click here to find a list of Clotiazepam suppliers with Written Confirmation (WC) on PharmaCompass.
Clotiazepam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Clotiazepam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Clotiazepam GMP manufacturer or Clotiazepam GMP API supplier for your needs.
A Clotiazepam CoA (Certificate of Analysis) is a formal document that attests to Clotiazepam's compliance with Clotiazepam specifications and serves as a tool for batch-level quality control.
Clotiazepam CoA mostly includes findings from lab analyses of a specific batch. For each Clotiazepam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Clotiazepam may be tested according to a variety of international standards, such as European Pharmacopoeia (Clotiazepam EP), Clotiazepam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Clotiazepam USP).
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