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    Chemistry

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    Also known as:
    Molecular Formula
    C18H24NO7P
    Molecular Weight
    397.4  g/mol
    InChI Key
    WUXLCJZUUHIXFY-UHFFFAOYSA-N
    Codeine Phosphate
    1 2D Structure

    Codeine Phosphate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol;phosphoric acid
    2.1.2 InChI
    InChI=1S/C18H21NO3.H3O4P/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-5(2,3)4/h3-6,11-13,17,20H,7-9H2,1-2H3;(H3,1,2,3,4)
    2.1.3 InChI Key
    WUXLCJZUUHIXFY-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(C=C4)O.OP(=O)(O)O
    2.2 Create Date
    2007-02-07
    3 Chemical and Physical Properties
    Molecular Weight 397.4 g/mol
    Molecular Formula C18H24NO7P
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count1
    Exact Mass397.12903910 g/mol
    Monoisotopic Mass397.12903910 g/mol
    Topological Polar Surface Area120 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity558
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count5
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

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    API Reference Price

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CHARLES DE G","customer":"SANOFI","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"450","totalValueFC":"1017049.6","currency":"EUR","unitRateINR":"42615","date":"20-Sep-2024","totalValueINR":"85230000","totalValueInUsd":"1017049.6","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"5696348","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"PARIS - CHARLES DE G","supplierAddress":"15, RUE TRAVERSIERE, 75012 PARIS Pa ris, , France SDNF France","customerAddress":"54-A, SIR MATHURADAS VASANJI ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727116200,"product":"CODEINE PHOSPHATE HEMIHYDRATE (CBN CERT NO.N-IMP-77\/2024 DT14.06.2024)","address":"54-A, SIR MATHURADAS VASANJI ROAD","city":"MUMBAI, MAHARASHTRA","supplier":"FRANCOPIA","supplierCountry":"FRANCE","foreign_port":"PARIS - CHARLES DE G","customer":"SANOFI","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"450","totalValueFC":"1017049.6","currency":"EUR","unitRateINR":"42615","date":"24-Sep-2024","totalValueINR":"85230000","totalValueInUsd":"1017049.6","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"5768937","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"PARIS - CHARLES DE G","supplierAddress":"15, RUE TRAVERSIERE, 75012 PARIS Pa ris, , France SDNF France","customerAddress":"54-A, SIR MATHURADAS VASANJI ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727289000,"product":"CODEINE PHOSPHATE HEMIHYDRATE (CBN CERT NO.N-IMP-79\/2024 DT14.06.2024)","address":"54-A, SIR MATHURADAS VASANJI ROAD","city":"MUMBAI, MAHARASHTRA","supplier":"FRANCOPIA","supplierCountry":"FRANCE","foreign_port":"PARIS - CHARLES DE G","customer":"SANOFI","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"450","totalValueFC":"1017049.6","currency":"EUR","unitRateINR":"42615","date":"26-Sep-2024","totalValueINR":"85230000","totalValueInUsd":"1017049.6","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"5812587","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"PARIS - CHARLES DE G","supplierAddress":"15, RUE TRAVERSIERE, 75012 PARIS Pa ris, , France SDNF France","customerAddress":"54-A, SIR MATHURADAS VASANJI ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728066600,"product":"CODEINE PHOSPHATE (CODEINE PHOSPHATE HEMIHYDRATE)","address":"WOCKHARDT TOWERS, BANDRA KURLA","city":"MUMBAI, MAHARASHTRA.","supplier":"ALCALIBER","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"WOCKHARDT","customerCountry":"INDIA","quantity":"40.00","actualQuantity":"40","unit":"KGS","unitRateFc":"300","totalValueFC":"13460","currency":"EUR","unitRateINR":"28275","date":"05-Oct-2024","totalValueINR":"1131000","totalValueInUsd":"13460","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"5966335","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRID","supplierAddress":"PASEO RECOLETOS,16 PLANTA 2 28001, MADRID (ES) SDNF Spain","customerAddress":"WOCKHARDT TOWERS, BANDRA KURLA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728066600,"product":"CODEINE PHOSPHATE (CODEINE PHOSPHATE HEMIHYDRATE)","address":"WOCKHARDT TOWERS, BANDRA KURLA","city":"MUMBAI, MAHARASHTRA.","supplier":"ALCALIBER","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"WOCKHARDT","customerCountry":"INDIA","quantity":"1860.00","actualQuantity":"1860","unit":"KGS","unitRateFc":"300","totalValueFC":"625891.4","currency":"EUR","unitRateINR":"28275","date":"05-Oct-2024","totalValueINR":"52591500","totalValueInUsd":"625891.4","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"5966335","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRID","supplierAddress":"PASEO RECOLETOS,16 PLANTA 2 28001, MADRID (ES) SDNF Spain","customerAddress":"WOCKHARDT TOWERS, BANDRA KURLA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728498600,"product":"CODEINE PHOSPHATE HEMIHYDRATE, CBN NO. N-IMP-72\/2024, DT:12.06.2024, QUOTA ALLOCATION NO: ND-110\/2024, DT: 07.03.2024","address":"PLOT NO.58-D,GOVT. INDL.ESTATE,","city":"MUMBAI ,MAHARASHTRA","supplier":"FRANCOPIA","supplierCountry":"FRANCE","foreign_port":"PARIS","customer":"RUSAN PHARMA","customerCountry":"INDIA","quantity":"2.50","actualQuantity":"2.5","unit":"KGS","unitRateFc":"450","totalValueFC":"1261.9","currency":"EUR","unitRateINR":"42412.5","date":"10-Oct-2024","totalValueINR":"106031.25","totalValueInUsd":"1261.9","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"6055631","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"PARIS","supplierAddress":"15 RUE TRAVERSIRE 75012 PARIS FRANCE FRANCE","customerAddress":"PLOT NO.58-D,GOVT. INDL.ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728498600,"product":"CODEINE PHOSPHATE HEMIHYDRATE, CBN NO. N-IMP-72\/2024, DT:12.06.2024, QUOTA ALLOCATION NO: ND-110\/2024, DT: 07.03.2024","address":"PLOT NO.58-D,GOVT. INDL.ESTATE,","city":"MUMBAI ,MAHARASHTRA","supplier":"FRANCOPIA","supplierCountry":"FRANCE","foreign_port":"PARIS","customer":"RUSAN PHARMA","customerCountry":"INDIA","quantity":"80.20","actualQuantity":"80.2","unit":"KGS","unitRateFc":"450","totalValueFC":"40481","currency":"EUR","unitRateINR":"42412.5","date":"10-Oct-2024","totalValueINR":"3401482.5","totalValueInUsd":"40481","indian_port":"Bombay Air","hs_no":"29391100","bill_no":"6055631","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"PARIS","supplierAddress":"15 RUE TRAVERSIRE 75012 PARIS FRANCE FRANCE","customerAddress":"PLOT NO.58-D,GOVT. INDL.ESTATE,"}]
    07-May-2021
    10-Oct-2024
    KGS
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    Average Price (USD/KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

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    (USD/KGS)    		 Number of Transactions

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    Drugs in Development

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    Elite Pharma Launches Acetaminophen and Codeine Tablets for Mild Pain Management

    Details:

    Acetaminophen & codeine phosphate is a pain relief medicine. It is approved for use in adults for relief of mild to moderate pain & the management of moderate to severe pain.


    Lead Product(s): Paracetamol,Codeine Phosphate

    Therapeutic Area: Neurology Brand Name: Tylenol-Generic

    Study Phase: ApprovedProduct Type: Small molecule

    Sponsor: Not Applicable

    Deal Size: Not Applicable Upfront Cash: Not Applicable

    Deal Type: Not Applicable October 09, 2024

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    01

    Elite Pharmaceuticals

    U.S.A
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    Lead Product(s) : Paracetamol,Codeine Phosphate

    Therapeutic Area : Neurology

    Highest Development Status : Approved

    Partner/Sponsor/Collaborator : Not Applicable

    Deal Size : Not Applicable

    Deal Type : Not Applicable

    DEALS_DEV arrow-down

    Elite Pharma Launches Acetaminophen and Codeine Tablets for Mild Pain Management

    Details : Acetaminophen & codeine phosphate is a pain relief medicine. It is approved for use in adults for relief of mild to moderate pain & the management of moderate to severe pain.

    Brand Name : Tylenol-Generic

    Molecule Type : Small molecule

    Upfront Cash : Not Applicable

    October 09, 2024

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    Temad Co

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    Regulatory Info :

    Registration Country : Iran

    Guaifenesin; Pseudoephedrine Hydrochloride; Codeine Phosphate

    Brand Name : Expectorant Codeine

    Dosage Form : Syrup

    Dosage Strength : 100MG; 30MG; 10MG

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    Registration Country : Iran

    Temad

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    Temad Co

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    Guaifenesin; Codeine Phosphate

    Brand Name : Guaicodin

    Dosage Form : Syrup

    Dosage Strength : 100MG; 10MG

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    Registration Country : Iran

    Temad

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    Faran Shimi Pharmaceutical

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    Virtual BoothFaran Shimi: Leading producer of high-quality APIs & alkaloid opiates, serving major pharmaceutical companies across the Middle East.

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    Acetaminophen; Codeine Phosphate

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    Dosage Form : Tablet

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    Faran Shimi Pharmaceutical

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    Regulatory Info : Narcotic (CDSA I)

    Registration Country : Canada

    CODEINE PHOSPHATE

    Brand Name : MERSYNDOL WITH CODEINE

    Dosage Form : TABLET

    Dosage Strength : 8MG

    Packaging : 24/100

    Approval Date :

    Application Number : 2047667

    Regulatory Info : Narcotic (CDSA I)

    Registration Country : Canada

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    Allergan Aesthetics

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    Regulatory Info : DISCN

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    ASPIRIN; BUTALBITAL; CAFFEINE; CODEINE PHOSPHATE

    Brand Name : FIORINAL W/CODEINE

    Dosage Form : CAPSULE;ORAL

    Dosage Strength : 325MG;50MG;40MG;30MG

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    Approval Date : 1990-10-26

    Application Number : 19429

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    LGM Pharma

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    Virtual BoothLGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

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    ASPIRIN; BUTALBITAL; CAFFEINE; CODEINE PHOSPHATE

    Brand Name : BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE

    Dosage Form : CAPSULE;ORAL

    Dosage Strength : 325MG;50MG;40MG;30MG

    Packaging :

    Approval Date : 2001-11-30

    Application Number : 75231

    Regulatory Info : RX

    Registration Country : USA

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    LGM Pharma

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    Regulatory Info : RX

    Registration Country : USA

    ACETAMINOPHEN; BUTALBITAL; CAFFEINE; CODEINE PHOSPHATE

    Brand Name : BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE

    Dosage Form : CAPSULE;ORAL

    Dosage Strength : 325MG;50MG;40MG;30MG

    Packaging :

    Approval Date : 2004-06-10

    Application Number : 76560

    Regulatory Info : RX

    Registration Country : USA

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    LGM Pharma

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    ACETAMINOPHEN; BUTALBITAL; CAFFEINE; CODEINE PHOSPHATE

    Brand Name : BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE

    Dosage Form : CAPSULE;ORAL

    Dosage Strength : 300MG;50MG;40MG;30MG

    Packaging :

    Approval Date : 2012-07-19

    Application Number : 76560

    Regulatory Info : RX

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    Aspen Pharmacare Holdings

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    Regulatory Info : Generic

    Registration Country : South Africa

    Codeine Phosphate

    Brand Name : Coughcod Senior

    Dosage Form : SYR

    Dosage Strength : 10mg/5ml

    Packaging : 200X1mg/5ml

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : South Africa

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    Aspen Pharmacare Holdings

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    Regulatory Info : Generic

    Registration Country : South Africa

    Codeine Phosphate

    Brand Name : Dolorol Forte

    Dosage Form : TAB

    Dosage Strength : 8mg

    Packaging : 50X1mg

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : South Africa

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - CAPSULE;ORAL - 325MG;50MG;40MG;30MG

    USFDA APPLICATION NUMBER - 19429

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    DOSAGE - CAPSULE;ORAL - 325MG;50MG;40MG;30MG

    USFDA APPLICATION NUMBER - 20232

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    DOSAGE - TABLET;ORAL - 300MG;15MG

    USFDA APPLICATION NUMBER - 85055

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    DOSAGE - TABLET;ORAL - 300MG;30MG

    USFDA APPLICATION NUMBER - 85055

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    DOSAGE - TABLET;ORAL - 300MG;60MG

    USFDA APPLICATION NUMBER - 85055

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    DOSAGE - TABLET;ORAL - 300MG;60MG

    USFDA APPLICATION NUMBER - 88629

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    DOSAGE - SYRUP;ORAL - 10MG/5ML;6.25MG/5ML

    USFDA APPLICATION NUMBER - 88763

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    Various finished formulations needed in Botswana [ENA06218] [Part 1/2]
    A consulting company based out of Portugal is looking for Europen/FDA/WHO GMP suppliers of various finished formulations. 1. Diazepam 10mg/2ml injection- 80,000 Ampoules 2. Hydrocortisone 100mg injection- 15000 vials 3. Hydralazine 25mg injection- 5000 vials 4. Adrenaline injection (1:1000)- 5000 Ampoules 5. Rabies Vaccine 0.5ml- 75000 Ampoules 6. Salbutamol solution (20 ml)- 8000 7. Enoxaparin 40iu Injection- 28800 8. Heparin 5000iu Injection- 70,000 vials 9. Fentanyl injection- 150,000 Ampoules 10. Codeine phosphate Tablets 30mg- 12,000 Units 11. Tramadol IV- 10,000 Ampoules 12. Paracetamol IV- 45,000 vials 13. Dexamethasone Injection 4mg- 75,000 Ampoule 14. Frusemide 20mg/ml- 100,000 Ampoules 15. Tranexamic acid injection 500mg - 43,000 Ampoules 16. Benzyl penicillin 5mu injections- 800,000 vials 17. Gentamycin 80mg/2ml injections- 250,000 Ampoules 18. Metronidazole 500mg injections- 150,000 vials 19. Amoxycillin 250mg capsules- 60,000 units 20. Cloxacillin 250mg capsules- 10,000 units 21. Flucloxacillin suspension 100ml- 8,000 units 22. Metformin 500mg tablets- 30,000 23. Glibenclamide 5mg tablets- 10,000 24. Biphasic 70/30iu (actraphane)- 120,000 vials 25. Atenolol 50mg tablets- 90,000 units 26. Nifedipine 20mg SR tablets- 90,000 units 27. Methyldopa 250mg tablets- 8,000 units 28. Hydrocholothiazide 25mg- 300,000 units 29. Enalapril 10mg- 100,000 units 30. Losartan 50mg- 327,000 units 31. Amlodipine 10mg- 50,000 units 32. Amlodipine 5mg- 50,000 units 33. Atracurium Besylate 10mg/ml (2.5ml)- 12,000 Ampoule 34. Atropine Sulphate 600mcg/ml (1ml)- 40,000 Ampoules 35. Bupivacaine Heavy 20mg/4ml- 24,000 Ampoules 36. Dobutamine 250mg/20ml- 10,000 Ampoules 37. Dopamine HCL 40mg/ml- 56,000 Ampoules 38. Ephedrine HCL 50mg/ml- 7,000 Ampoules
    06 Jan 2020

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    06 Jan 2020

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    06 Jan 2020

    Market Place
    Enquiry// Antibiotics & Other Products needed in the Czech Republic [ENA00040]
    A well established Business Development Consultant in the Czech Republic has received a request for the following products - Codeine 15 Mg x 10 tabs 45,000 boxes and 30 Mg x 10 tabs 100 000 boxes for Czech and Slovakia; Ampicillin/ Sulbactam 1.5 G dry injection Y1- 80,000, Y2- 1,36 000, Y3- 1,70 000 boxes, ; Amoxicillin/Clavulanic Acid 600 mg x 1 Amp Y1- 21,000, Y2- 35,000, Y3- 44,000 boxes and 1.2 G x 1 Amp Y1- 4,46 000, Y2- 7,58 000, Y3- 9,50 000 boxes and Diosmectite 3 G x 10 Sachets 65,000 boxes.
    20 Jul 2016

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    20 Jul 2016

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    20 Jul 2016

    Market Place
    In-licensing Request//Codeine Phosphate 15mg and 30mg EU CTD Dossier needed for Central Europe [EN00331]
    Searching to purchase a dossier of Codeine Phosphate 15mg and 30mg without supply or with a limited supply agreement during the production transfer phase. Non EU Dossier with a good Module III would also be acceptable.
    19 Mar 2016

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    19 Mar 2016

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    19 Mar 2016

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