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    Chemistry

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    Also known as:
    Molecular Formula
    C15H26K2N3O7P
    Molecular Weight
    469.55  g/mol
    InChI Key
    DTEQBACKLXLPHP-UHFFFAOYSA-L
    Collagenase Inhibitor
    1 2D Structure

    Collagenase Inhibitor

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    dipotassium;2-[[1-[2-[[3-methylbutoxy(oxido)phosphoryl]amino]acetyl]pyrrolidine-2-carbonyl]amino]propanoate
    2.1.2 InChI
    InChI=1S/C15H28N3O7P.2K/c1-10(2)6-8-25-26(23,24)16-9-13(19)18-7-4-5-12(18)14(20)17-11(3)15(21)22;;/h10-12H,4-9H2,1-3H3,(H,17,20)(H,21,22)(H2,16,23,24);;/q;2*+1/p-2
    2.1.3 InChI Key
    DTEQBACKLXLPHP-UHFFFAOYSA-L
    2.1.4 Canonical SMILES
    CC(C)CCOP(=O)(NCC(=O)N1CCCC1C(=O)NC(C)C(=O)[O-])[O-].[K+].[K+]
    2.2 Create Date
    2009-08-08
    3 Chemical and Physical Properties
    Molecular Weight 469.55 g/mol
    Molecular Formula C15H26K2N3O7P
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count9
    Exact Mass469.0782501 g/mol
    Monoisotopic Mass469.0782501 g/mol
    Topological Polar Surface Area151 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity556
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3

    API SUPPLIERS

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    Nordmark Arzneimittel GmbH & Co. K...

    Germany

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Medlab Asia & Asia Health
    Not Confirmed
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    Nordmark Arzneimittel GmbH & Co. K...

    Germany

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Medlab Asia & Asia Health
    Not Confirmed
    USDMF arrow-down Click Us! arrow-down
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 22761

    Submission : 2009-05-04

    Status : Active

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : R1-CEP 2002-003 - Rev 01

    Issue Date : 2021-11-16

    Type : TSE

    Substance Number :

    Status : Valid

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    Nordmark Arzneimittel GmbH & Co. K...

    Germany

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Medlab Asia & Asia Health
    Not Confirmed
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    Nordmark Arzneimittel GmbH & Co. K...

    Germany

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    Medlab Asia & Asia Health
    Not Confirmed
    USDMF arrow-down
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 29146

    Submission : 2015-05-07

    Status : Active

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    03

    SEWON CELLONTECH CO LTD

    South Korea

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Medlab Asia & Asia Health
    Not Confirmed
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    SEWON CELLONTECH CO LTD

    South Korea

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Medlab Asia & Asia Health
    Not Confirmed
    USDMF arrow-down
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 21463

    Submission : 2008-03-03

    Status : Active

    Type : II

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    SIGMA TAU

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    Medlab Asia & Asia Health
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    SIGMA TAU

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    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Medlab Asia & Asia Health
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 10658

    Submission : 1994-01-06

    Status : Inactive

    Type : II

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    Country

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Medlab Asia & Asia Health
    Not Confirmed
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    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Medlab Asia & Asia Health
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 18631

    Submission : 1978-10-09

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    Medlab Asia & Asia Health
    Not Confirmed
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    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Medlab Asia & Asia Health
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 18639

    Submission : 1995-04-11

    Status : Inactive

    Type : II

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    01

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    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 22761

    Submission : 2009-05-04

    Status : Active

    Type : II

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    Nordmark Pharma Gmbh

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    Nordmark Pharma Gmbh

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    Medlab Asia & Asia Health
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    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 29146

    Submission : 2015-05-07

    Status : Active

    Type : II

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    Sewon Cellontech Co Ltd

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    Not Confirmed

    03

    Sewon Cellontech Co Ltd

    South Korea
    arrow
    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 21463

    Submission : 2008-03-03

    Status : Active

    Type : II

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    Sigma F And D Div Ltd

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    Sigma F And D Div Ltd

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    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 10658

    Submission : 1994-01-06

    Status : Inactive

    Type : II

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    Advance Biofactures Corp

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    Advance Biofactures Corp

    Country
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    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 18639

    Submission : 1995-04-11

    Status : Inactive

    Type : II

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    Advance Biofactures Corp

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    Not Confirmed

    06

    Advance Biofactures Corp

    Country
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    Medlab Asia & Asia Health
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 18631

    Submission : 1978-10-09

    Status : Inactive

    Type : II

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    Cristalia Produtos Quimicos Farma. ...

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    Regulatory Info : Generic

    Registration Country : Brazil

    Collagenase Inhibitor

    Brand Name : KOLLAGENASE

    Dosage Form : OINTMENT

    Dosage Strength : 0.6MCG/G

    Packaging : TUBE X3OG

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    Collagenase Inhibitor

    Brand Name : KOLLAGENASE

    Dosage Form : OINTMENT

    Dosage Strength : 0.6MCG/G

    Packaging : TUBE X 5O G + SPATULA

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    Cristalia Produtos Quimicos Farma. ...

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    Regulatory Info : Generic

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    Collagenase Inhibitor

    Brand Name : KOLLAGENASE

    Dosage Form : OINTMENT

    Dosage Strength : 0.6MCG/G

    Packaging : 10 TUBES X 300 +SPATULA

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    Regulatory Info : Generic

    Registration Country : Brazil

    Collagenase Inhibitor; Chloramphenicol

    Brand Name : KOLLAGENASE C/CLORANF.

    Dosage Form : OINTMENT

    Dosage Strength :

    Packaging : 10 TUBES X 300

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    Cristalia Produtos Quimicos Farma. ...

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    Regulatory Info : Generic

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    Collagenase Inhibitor; Chloramphenicol

    Brand Name : KOLLAGENASE C/CLORANF.

    Dosage Form : OINTMENT

    Dosage Strength :

    Packaging : TUBE X 15 G + SPATULA

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    Cristalia Produtos Quimicos Farma. ...

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    Regulatory Info : Generic

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    Collagenase Inhibitor; Chloramphenicol

    Brand Name : KOLLAGENASE C/CLORANF.

    Dosage Form : OINTMENT

    Dosage Strength :

    Packaging : TUBE X3OG

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    Cristalia Produtos Quimicos Farma. ...

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    Collagenase Inhibitor; Chloramphenicol

    Brand Name : KOLLAGENASE C/CLORANF.

    Dosage Form : OINTMENT

    Dosage Strength :

    Packaging : TUBE X 5O G + SPATULA

    Approval Date :

    Application Number :

    Regulatory Info : Generic

    Registration Country : Brazil

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    SMITH & NEPHEW INC

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    Regulatory Info :

    Registration Country : USA

    COLLAGENASE

    Brand Name : SANTYL

    Dosage Form : OINTMENT;TOPICAL

    Dosage Strength : 250U/GRAM

    Packaging :

    Approval Date :

    Application Number : 101995

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    Regulatory Info :

    Registration Country : Italy

    Collagenase Inhibitor

    Brand Name : Noruxol

    Dosage Form :

    Dosage Strength : Pom Derm 30 G  

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    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Italy

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    Regulatory Info :

    Registration Country : Italy

    Collagenase Inhibitor

    Brand Name : Noruxol

    Dosage Form :

    Dosage Strength : Pom Derm 10 G  

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    Approval Date :

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    RLD :

    TE Code :

    COLLAGENASE

    Brand Name : SANTYL

    Dosage Form : OINTMENT;TOPICAL

    Dosage Strength : 250U/GRAM

    Approval Date :

    Application Number : 101995

    RX/OTC/DISCN :

    RLD :

    TE Code :

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