Find Comelian manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Dilazep hydrochloride, Cormelian, Dilazep hcl, Asta c 4898, Labitan, Lv48lw10eo
Molecular Formula
C31H46Cl2N2O10
Molecular Weight
677.6  g/mol
InChI Key
VILIWRRWAWKXRW-UHFFFAOYSA-N

Comelian
Coronary vasodilator with some antiarrhythmic activity.
1 2D Structure

Comelian

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepane-1,4-diium-1-yl]propyl 3,4,5-trimethoxybenzoate;dichloride
2.1.2 InChI
InChI=1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H
2.1.3 InChI Key
VILIWRRWAWKXRW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=CC(=CC(=C1OC)OC)C(=O)OCCC[NH+]2CCC[NH+](CC2)CCCOC(=O)C3=CC(=C(C(=C3)OC)OC)OC.[Cl-].[Cl-]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Asta C 4898

2. Biopropazepan Trimethoxybenzoate

3. C 4898, Asta

4. Cormelian

5. Dilazep

6. Trimethoxybenzoate, Biopropazepan

2.2.2 Depositor-Supplied Synonyms

1. Dilazep Hydrochloride

2. Cormelian

3. Dilazep Hcl

4. Asta C 4898

5. Labitan

6. Lv48lw10eo

7. 20153-98-4

8. Asta C

9. (tetrahydro-1h-1,4-diazepine-1,4(5h)-diyl)di(propane-1,3-diyl) Bis(3,4,5-trimethoxybenzoate) Dihydrochloride

10. Ccris 3782

11. Einecs 243-548-8

12. K-285

13. Unii-lv48lw10eo

14. Dilazep Dihydrochloride [jan]

15. As 05

16. Dtxsid201017379

17. Hms3261i19

18. Tox21_500369

19. N,n'-bis(3-(3,4,5-trimethoxybenzoyloxy)propyl)homopiperazine Dihydrochloride

20. Ccg-221673

21. Lp00369

22. Nsc 760096

23. 1,4-bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)perhydro-1,4-diazepine Dihydrochloride

24. N,n'-(bis-omega-hydroxypropyl)homopiperazine 3,4,5-trimethoxybenzoate Dihydrochloride

25. Tetrahydro-1h-1,4-diazepine-1,4(5h)-dipropanol Bis(3,4,5-trimethoxybenzoate) Dihydrochloride

26. Ncgc00093803-01

27. Ncgc00261054-01

28. Benzoic Acid, 3,4,5-trimethoxy-, Diester With Tetrahydro-1h-1,4-diazepine-1,4(5h)dipropanol, Dihydrochloride

29. Eu-0100369

30. D 5294

2.3 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 677.6 g/mol
Molecular Formula C31H46Cl2N2O10
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count12
Rotatable Bond Count18
Exact Mass676.2529511 g/mol
Monoisotopic Mass676.2529511 g/mol
Topological Polar Surface Area117 Ų
Heavy Atom Count45
Formal Charge0
Complexity727
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


ABOUT THIS PAGE

Looking for 20153-98-4 / Comelian API manufacturers, exporters & distributors?

Comelian manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Comelian API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Comelian manufacturer or Comelian supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Comelian manufacturer or Comelian supplier.

PharmaCompass also assists you with knowing the Comelian API Price utilized in the formulation of products. Comelian API Price is not always fixed or binding as the Comelian Price is obtained through a variety of data sources. The Comelian Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Comelian

Synonyms

Dilazep hydrochloride, Cormelian, Dilazep hcl, Asta c 4898, Labitan, Lv48lw10eo

Cas Number

20153-98-4

About Comelian

Coronary vasodilator with some antiarrhythmic activity.

Comelian Manufacturers

A Comelian manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Comelian, including repackagers and relabelers. The FDA regulates Comelian manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Comelian API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Comelian Suppliers

A Comelian supplier is an individual or a company that provides Comelian active pharmaceutical ingredient (API) or Comelian finished formulations upon request. The Comelian suppliers may include Comelian API manufacturers, exporters, distributors and traders.

Comelian GMP

Comelian Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Comelian GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Comelian GMP manufacturer or Comelian GMP API supplier for your needs.

Comelian CoA

A Comelian CoA (Certificate of Analysis) is a formal document that attests to Comelian's compliance with Comelian specifications and serves as a tool for batch-level quality control.

Comelian CoA mostly includes findings from lab analyses of a specific batch. For each Comelian CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Comelian may be tested according to a variety of international standards, such as European Pharmacopoeia (Comelian EP), Comelian JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Comelian USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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