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    Chemistry

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    Also known as: Oxocopper, Copper oxide (cuo), Copper monoxide, Banacobru ol, Chrome brown, Copper brown
    Molecular Formula
    CuO
    Molecular Weight
    79.55  g/mol
    InChI Key
    QPLDLSVMHZLSFG-UHFFFAOYSA-N
    Copper Oxide
    1 2D Structure

    Copper Oxide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    oxocopper
    2.1.2 InChI
    InChI=1S/Cu.O
    2.1.3 InChI Key
    QPLDLSVMHZLSFG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    O=[Cu]
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Copper Dioxide (cuo2)

    2. Copper Oxide (cuo)

    3. Cupric Oxide

    2.2.2 Depositor-Supplied Synonyms

    1. Oxocopper

    2. Copper Oxide (cuo)

    3. Copper Monoxide

    4. Banacobru Ol

    5. Chrome Brown

    6. Copper Brown

    7. Copper Monooxide

    8. Copper(2+) Oxide

    9. C.i. Pigment Black 15

    10. Copper (ii) Oxide

    11. Cu-o Linkage

    12. C.i. 77403

    13. Mfcd00010979

    14. Cuo

    15. Paramelaconite

    16. Copacaps

    17. Copporal

    18. Natural Tenorite

    19. Wolmanac Concentrate

    20. Boliden Salt K-33

    21. Caswell No. 265

    22. Ci Pigment Black 15

    23. Boliden-cca Wood Preservative

    24. Cca Type C Wood Preservative

    25. Hsdb 266

    26. Osmose K-33 Wood Preservative

    27. Osmose P-50 Wood Preservative

    28. Osmose K-33-a Wood Preservative

    29. Osmose K-33-c Wood Preservative

    30. Einecs 215-269-1

    31. Nsc 83537

    32. Epa Pesticide Chemical Code 042401

    33. Unii-v1xjq704r4

    34. Ci 77403

    35. Copper-oxygen

    36. Farboil Super Tropical Anti-fouling 1260

    37. Copper(ii)oxide

    38. Copper Ii Oxide

    39. Copper Oxide Ink

    40. Copper Oxide, Cuo

    41. Copper Oxide Powder

    42. Copper-(ii) Oxide

    43. Copper Oxide Dispersion

    44. Copper Oxide Nanopowder

    45. Cupric Oxide Nanopowder

    46. Copper Oxide Nano-chains

    47. Copper(ii) Oxide, Cp

    48. Copper Oxide Nanoparticles

    49. Copper(ii) Oxide, Powder

    50. Ec 215-269-1

    51. Copper(ii) Oxide, Puratronic?

    52. Copper Oxide Powder, 99+% Nano

    53. Nsc83537

    54. Copper(ii) Oxide, Lr, >=97%

    55. Copper Oxide Nanoparticles Dispersion

    56. Akos015950660

    57. Copper(ii) Oxide (99.995%-cu)

    58. Copper Oxide Nanoparticles / Nanopowder

    59. Copper(ii) Oxide, Acs Reagent, >=99.0%

    60. Copper(ii) Oxide, Powder, <10 Mum, 98%

    61. Cs-0016015

    62. Ft-0624050

    63. Chromium Silicide (crsi2) Sputtering Targets

    64. Copper(ii) Oxide, >=99.0% (rt), Granular

    65. Copper(ii) Oxide, 99.999% Trace Metals Basis

    66. Copper(ii) Oxide, P.a., Acs Reagent, 99.0%

    67. J-520121

    68. Q27458610

    69. Copper(ii) Oxide, Powder, 99.99% Trace Metals Basis

    70. Copper(ii) Oxide, Powder, 99.995% Trace Metals Basis

    71. Copper(ii) Oxide, Nanopowder, <50 Nm Particle Size (tem)

    72. Copper(ii) Oxide, Puriss. P.a., >=99.0% (rt), Powder

    73. Copper(ii) Oxide, Nanotubes, Diam. X L 10-12 Nm X 75-100 Nm

    74. Copper(ii) Oxide, Needles, Mixture Of Cuo And Cu2o, Acs Reagent

    75. Pedot Pss Poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate )

    76. Copper(ii) Oxide On Alumina, 14-20 Mesh, Extent Of Labeling: 13 Wt. % Loading

    2.3 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 79.55 g/mol
    Molecular Formula CuO
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass78.924512 g/mol
    Monoisotopic Mass78.924512 g/mol
    Topological Polar Surface Area17.1 Ų
    Heavy Atom Count2
    Formal Charge0
    Complexity2
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Trace Elements

    A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) (See all compounds classified as Trace Elements.)

    4.2 Absorption, Distribution and Excretion

    The pulmonary uptake of copper oxide /occurred/ in rats exposed to aerosols containing 50-80 mg/cu m. Animals were exposed for 15, 30, 45, or 60 minutes and killed immediately. Another group was exposed for 180 minutes and killed at 0, 3, 6, 12, 18, or 24 hours after exposure. Electron microscopic histologic examination showed that absorption of copper had occurred in animals exposed for 180 minutes. Copper oxide particles penetrated the epithelial cells of alveoli and were found in plasma 6 hours after exposure began. Copper oxide was also observed in the proximal convoluted tubules of the kidney. /Copper oxide/

    USEPA; Drinking Water Criteria Document for Copper (Final Draft) p.III-3 (1985) EPA-600/X-84-190-1

    VET: COPPER SOURCE. 80% COPPER CONTENT. LOW ABSORPTION RATE & HIGH FECAL EXCRETION RATE IN CATTLE & SWINE FEEDING TRIALS. IN GENERAL MONOGASTRIC ANIMALS UTILIZE /CUPRIC OXIDE/ BETTER THAN RUMINANTS. POULTRY UTILIZATION IS SOMEWHERE BETWEEN THE TWO.

    Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 135

    Cheviot ewes (mean live weight 50 kg) were given single doses of 0, 2.5, 5, 10, or 20 g cupric oxide particles in gelatin capsules while receiving a diet of marginal copper content based on pelleted oats. After 65 days, liver copper concentrations had increased curvilinearly in relation to dose and all ewes given 10 or 20 g cupric oxide particles showed increases of at least 13.4 mmol/kg dry matter (850 ppm). Liver copper concentrations had generally declined after 85 days but biochemical and histological evidence of copper toxicity was recorded in one ewe which had received 20 g cupric oxide particles. Despite marked variations between individual sheep, a dose of 0.1 g/kg liveweight (5 g) was considered to be safe and did not induce clinical copper toxicity in five sheep of the susceptible North Ronaldsay breed given the same basal diet.

    PMID:3589168 Suttle NF; Res Vet Sci 42 (2): 219-23 (1987)

    Crossbred steers, mean initial live weight 220 kg, were given a diet of barley and hay ad libitum. Each animal received a single oral does of 0, 5, 10, 20, or 40 g cupric oxide particles. A dose of 5 g cupric oxide particles increased liver copper stores for about 240 days and higher doses increased liver stores for longer but 40 g was no more effective than 20 g (85 mg/kg live weight). Variation among individuals was marked but the highest liver copper concentration recorded (7.59 mmol/kg dry matter) produced no biochemical evidence of copper toxicity. Cupric oxide particles were separated into three fractions, clumps, short rods and long; and 5 mg/kg live weight of each fraction given to steers of 173 kg mean live weight. The form of the particles did not affect either their retention in the alimentary tract or the accumulation of copper in the liver.

    PMID:3589169 Suttle NF; Res Vet Sci 42 (2): 224-7 (1987)

    For more Absorption, Distribution and Excretion (Complete) data for COPPER(II) OXIDE (6 total), please visit the HSDB record page.

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    ABOUT THIS PAGE

    Copper Oxide Manufacturers

    A Copper Oxide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Copper Oxide, including repackagers and relabelers. The FDA regulates Copper Oxide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Copper Oxide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Copper Oxide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Copper Oxide Suppliers

    A Copper Oxide supplier is an individual or a company that provides Copper Oxide active pharmaceutical ingredient (API) or Copper Oxide finished formulations upon request. The Copper Oxide suppliers may include Copper Oxide API manufacturers, exporters, distributors and traders.

    click here to find a list of Copper Oxide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Copper Oxide NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Copper Oxide as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Copper Oxide API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Copper Oxide as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Copper Oxide and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Copper Oxide NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Copper Oxide suppliers with NDC on PharmaCompass.

    Copper Oxide GMP

    Copper Oxide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Copper Oxide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Copper Oxide GMP manufacturer or Copper Oxide GMP API supplier for your needs.

    Copper Oxide CoA

    A Copper Oxide CoA (Certificate of Analysis) is a formal document that attests to Copper Oxide's compliance with Copper Oxide specifications and serves as a tool for batch-level quality control.

    Copper Oxide CoA mostly includes findings from lab analyses of a specific batch. For each Copper Oxide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Copper Oxide may be tested according to a variety of international standards, such as European Pharmacopoeia (Copper Oxide EP), Copper Oxide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Copper Oxide USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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