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ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 148465-45-6, Cid 17397714, Zinc9497828, Akos016487279, Z164754034, 923916-82-9
Molecular Formula
C18H16N2O3
Molecular Weight
308.3  g/mol
InChI Key
JDNAIBCYTQGWFC-UHFFFAOYSA-N

Crofelemer
1 2D Structure

Crofelemer

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[(2-methoxyphenyl)methyl]-5-phenyl-1,2-oxazole-3-carboxamide
2.1.2 InChI
InChI=1S/C18H16N2O3/c1-22-16-10-6-5-9-14(16)12-19-18(21)15-11-17(23-20-15)13-7-3-2-4-8-13/h2-11H,12H2,1H3,(H,19,21)
2.1.3 InChI Key
JDNAIBCYTQGWFC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=CC=CC=C1CNC(=O)C2=NOC(=C2)C3=CC=CC=C3
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. 148465-45-6

2. Cid 17397714

3. Zinc9497828

4. Akos016487279

5. Z164754034

6. 923916-82-9

2.3 Create Date
2007-11-13
3 Chemical and Physical Properties
Molecular Weight 308.3 g/mol
Molecular Formula C18H16N2O3
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass308.11609238 g/mol
Monoisotopic Mass308.11609238 g/mol
Topological Polar Surface Area64.4 Ų
Heavy Atom Count23
Formal Charge0
Complexity385
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 1  
Drug NameMYTESI
Active IngredientCROFELEMER
CompanyNAPO PHARMS INC (Application Number: N202292. Patents: 7323195, 7341744, 8574634, 8962680, 9585868)

API Reference Price

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[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1634841000,"product":"CROFELEMER - BULK DRUG","address":"PLOT 170-172, CHANDRAMOULI,INDUSTR IAL ESTATE, MOHOL BAZARPETH","city":"SOLAPUR,MAHARASHTRA","supplier":"GLENMARK PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MEMPHIS, TN","customer":"THERMO FISHER SCIENTIFIC","customerCountry":"UNITED STATES","quantity":"38.60","actualQuantity":"38.602","unit":"KGS","unitRateFc":"7926","totalValueFC":"302434.9","currency":"USD","unitRateINR":586912.59520232119,"date":"22-Oct-2021","totalValueINR":"22656000","totalValueInUsd":"302434.9","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"5480870","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"PLOT 170-172, CHANDRAMOULI,INDUSTR IAL ESTATE, MOHOL BAZARPETH, SOLAPUR,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1642444200,"product":"CROFELEMER - BULK DRUG","address":"Plot 170-172, Chandramouli Industrial Estate, Mohol Bazarpeth","city":"Solapur","supplier":"GLENMARK PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MEMPHIS, TN","customer":"SHARP","customerCountry":"UNITED STATES","quantity":"83.11","actualQuantity":"83.108","unit":"KGS","unitRateFc":"7926","totalValueFC":"651251.9","currency":"USD","unitRateINR":583746.45040188672,"date":"18-Jan-2022","totalValueINR":"48514000","totalValueInUsd":"651251.9","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"7546077","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"Plot 170-172, Chandramouli Industrial Estate, Mohol Bazarpeth, Solapur","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1657132200,"product":"CROFELEMER","address":"Plot 170-172, Chandramouli Industrial Estate, Mohol Bazarpeth","city":"Solapur","supplier":"GLENMARK PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MEMPHIS, TN","customer":"TO THE ORDER","customerCountry":"UNITED STATES","quantity":"68.44","actualQuantity":"68.436","unit":"KGS","unitRateFc":"7926","totalValueFC":"526959.6","currency":"USD","unitRateINR":612280.08650417905,"date":"07-Jul-2022","totalValueINR":"41902000","totalValueInUsd":"526959.6","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"2666016","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"Plot 170-172, Chandramouli Industrial Estate, Mohol Bazarpeth, Solapur","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703615400,"product":"ACTIVE PHARMACEUTICALS INGREDIENTS (API)EXPORT INVOICE NUMBER:F32418001214 DT.29.06.2023 CROFELEMER","address":"PLOT 170-172, CHANDRAMOULI,INDUSTR","city":"SOLAPUR,MAHARASHTRA","supplier":"GLENMARK PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MEMPHIS, TN","customer":"TO THE ORDER","customerCountry":"UNITED STATES","quantity":"11.88","actualQuantity":"11.876","unit":"KGS","unitRateFc":"7926","totalValueFC":"93509.2","currency":"USD","unitRateINR":655439.54193331092,"date":"27-Dec-2023","totalValueINR":"7784000","totalValueInUsd":"93509.2","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"6326080","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"PLOT 170-172, CHANDRAMOULI,INDUSTR, SOLAPUR,MAHARASHTRA","customerAddress":""}]
22-Oct-2021
27-Dec-2023
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Quantity (KGS) & Unit rate (USD/KGS) over time

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