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    Crotamiton

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

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    $ API Ref.Price (USD/KG) : 46Xls

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    2D Structure
    Also known as: 483-63-6, N-ethyl-o-crotonotoluidide, Trans-crotamiton, Crotamitone, Eurax, Crotalgin
    Molecular Formula
    C13H17NO
    Molecular Weight
    203.28  g/mol
    InChI Key
    DNTGGZPQPQTDQF-XBXARRHUSA-N
    FDA UNII
    2EEH27851Y
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (E)-N-ethyl-N-(2-methylphenyl)but-2-enamide
    2.1.2 InChI
    InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+
    2.1.3 InChI Key
    DNTGGZPQPQTDQF-XBXARRHUSA-N
    2.1.4 Canonical SMILES
    CCN(C1=CC=CC=C1C)C(=O)C=CC
    2.1.5 Isomeric SMILES
    CCN(C1=CC=CC=C1C)C(=O)/C=C/C
    2.2 Other Identifiers
    2.2.1 UNII
    2EEH27851Y
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Eurax

    2.3.2 Depositor-Supplied Synonyms

    1. 483-63-6

    2. N-ethyl-o-crotonotoluidide

    3. Trans-crotamiton

    4. Crotamitone

    5. Eurax

    6. Crotalgin

    7. 124236-29-9

    8. Veteusan

    9. Crotamitex

    10. Eurasil

    11. Euraxil

    12. Crotamitonum

    13. Crotonyl-n-ethyl-o-toluidine

    14. Crotamiton, (e)-

    15. 2-butenamide, N-ethyl-n-(2-methylphenyl)-

    16. (e)-n-ethyl-n-(2-methylphenyl)but-2-enamide

    17. (e)-n-ethyl-n-(o-tolyl)but-2-enamide

    18. O-crotonotoluidide, N-ethyl-

    19. (2e)-n-ethyl-n-(2-methylphenyl)but-2-enamide

    20. 2eeh27851y

    21. 2-butenamide, N-ethyl-n-(2-methylphenyl)-, (e)-

    22. Mfcd00026989

    23. 2-butenamide, N-ethyl-n-(2-methylphenyl)-, (2e)-

    24. Nsc-758951

    25. Crotan

    26. Caswell No. 431b

    27. Bestloid

    28. Crotamitonum [inn-latin]

    29. Smr000059145

    30. N-ethyl-n-(2-methylphenyl)but-2-enamide

    31. Sr-01000759366

    32. Einecs 207-596-3

    33. Unii-d6s4o4xd0h

    34. Epa Pesticide Chemical Code 055701

    35. Chebi:31439

    36. Brn 3275497

    37. N-ethyl-n-(2-methylphenyl)-2-butenamide

    38. Unii-2eeh27851y

    39. Ai3-17732

    40. N-crotonyl-n-ethyl-o-toluidine

    41. (e)-crotamiton

    42. Crotamiton [usp:inn:ban:jan]

    43. Eurax (tn)

    44. Prestwick2_000951

    45. Prestwick3_000951

    46. N-ethylcrotono-o-toluidide

    47. N-ethyl-o-crotonotoluidine

    48. G 7857

    49. N-ethyl- O-crotonotoluidide

    50. D6s4o4xd0h

    51. Schembl32934

    52. Bspbio_000942

    53. Bspbio_002722

    54. Crotamiton (jan/usp/inn)

    55. 3-12-00-01856 (beilstein Handbook Reference)

    56. Mls000759489

    57. Mls001424003

    58. Mls002222307

    59. Mls002695895

    60. N-ethyl-ortho-crotonotoluidide

    61. Spectrum1505271

    62. Bpbio1_001038

    63. Component Of Eurax (salt/mix)

    64. Chembl1200709

    65. Gtpl11165

    66. Zinc56427

    67. N-ethyl-o-crotonotoluidide, 97%

    68. Dtxsid101256463

    69. Hms1570p04

    70. Hms1922p21

    71. Hms2051e10

    72. Hms2090a10

    73. Hms2093o12

    74. Hms2097p04

    75. Hms2234e16

    76. Hms3714p04

    77. Pharmakon1600-01505271

    78. Bcp13315

    79. Hy-b1177

    80. N-ethyl-n-(o-tolyl)but-2-enamide

    81. Nsc78382

    82. Ccg-39402

    83. Nsc-78382

    84. Nsc758951

    85. S1711

    86. (e)-n-ethyl-n-o-tolylbut-2-enamide

    87. Akos015892746

    88. Cs-4730

    89. Nc00107

    90. Nsc 758951

    91. Ncgc00094571-01

    92. Ncgc00094571-02

    93. Ncgc00094571-03

    94. Ncgc00094571-04

    95. Ncgc00094571-05

    96. As-11641

    97. Trans-n-ethyl-n-(o-tolyl)-2-butenamide

    98. Sbi-0206763.p001

    99. Ab00513973

    100. E0814

    101. N-ethyl-n-(2-methylphenyl)-2-butenamide #

    102. D01381

    103. D70888

    104. (2e)-n-ethyl-n-(2-methylphenyl)-2-butenamide

    105. Ab00513973-09

    106. Ab00513973_10

    107. 483c636

    108. A827519

    109. Q-200893

    110. Q2439845

    111. Sr-01000759366-4

    112. Sr-01000759366-6

    113. Brd-k13240564-001-01-8

    114. Brd-k57179821-001-05-5

    115. Brd-k57179821-001-08-9

    116. Crotamiton, British Pharmacopoeia (bp) Reference Standard

    117. Crotamiton, European Pharmacopoeia (ep) Reference Standard

    118. Crotamiton, United States Pharmacopeia (usp) Reference Standard

    119. N-ethyl-o-crotonotoluidide; Crotamitone; Crotalgin; Eurasil; Euraxil

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 203.28 g/mol
    Molecular Formula C13H17NO
    XLogP32.8
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count3
    Exact Mass203.131014166 g/mol
    Monoisotopic Mass203.131014166 g/mol
    Topological Polar Surface Area20.3 Ų
    Heavy Atom Count15
    Formal Charge0
    Complexity235
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameCrotan
    PubMed HealthCrotamiton (On the skin)
    Drug ClassesScabicide
    Drug LabelEurax (crotamiton USP) is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. Eurax provides 10% (w/w) of the synthetic, crotamiton USP, in a vanishing-cream or emollient-lotion base containing: carbomer-934, cety...
    Active IngredientCrotamiton
    Dosage FormLotion
    RouteTopical
    Strength10%
    Market StatusPrescription
    CompanySummers

    2 of 4  
    Drug NameEurax
    Active IngredientCrotamiton
    Dosage FormLotion; Cream
    RouteTopical
    Strength10%
    Market StatusPrescription
    CompanyRanbaxy

    3 of 4  
    Drug NameCrotan
    PubMed HealthCrotamiton (On the skin)
    Drug ClassesScabicide
    Drug LabelEurax (crotamiton USP) is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. Eurax provides 10% (w/w) of the synthetic, crotamiton USP, in a vanishing-cream or emollient-lotion base containing: carbomer-934, cety...
    Active IngredientCrotamiton
    Dosage FormLotion
    RouteTopical
    Strength10%
    Market StatusPrescription
    CompanySummers

    4 of 4  
    Drug NameEurax
    Active IngredientCrotamiton
    Dosage FormLotion; Cream
    RouteTopical
    Strength10%
    Market StatusPrescription
    CompanyRanbaxy

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Pesticides

    Chemicals used to destroy pests of any sort. The concept includes fungicides (FUNGICIDES, INDUSTRIAL); INSECTICIDES; RODENTICIDES; etc. (See all compounds classified as Pesticides.)