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1. Cumene Hydroperoxide, Sodium Salt
2. Cumyl Hydroperoxide
3. Cumylhydroperoxide
4. Isopropyl Benzene Hydroperoxide
1. Cumyl Hydroperoxide
2. 80-15-9
3. Hydroperoxide, 1-methyl-1-phenylethyl
4. Cumenyl Hydroperoxide
5. Alpha,alpha-dimethylbenzyl Hydroperoxide
6. Cumolhydroperoxid
7. 7-cumyl Hydroperoxide
8. Cument Hydroperoxide
9. Hydroperoxyde De Cumene
10. Hydroperoxyde De Cumyle
11. Isopropylbenzene Hydroperoxide
12. Cumeenhydroperoxyde
13. Kumenylhydroperoxid
14. 2-hydroperoxypropan-2-ylbenzene
15. 7-hydroperoxykumen
16. Rcra Waste Number U096
17. 1-methyl-1-phenylethyl Hydroperoxide
18. Idroperossido Di Cumene
19. Idroperossido Di Cumolo
20. Percumyl H
21. Pg7jd54x4i
22. Dtxsid3024869
23. Chebi:78673
24. Cumolhydroperoxide
25. .alpha.,.alpha.-dimethylbenzyl Hydroperoxide
26. Hydroperoxide, .alpha.,.alpha.-dimethylbenzyl
27. Cumene Hydroperoxide (80per Cent, Technical Grade)
28. Hydroperoxide De Cumene
29. Cumolhydroperoxid [german]
30. Cumeenhydroperoxyde [dutch]
31. Kumenylhydroperoxid [czech]
32. 7-hydroperoxykumen [czech]
33. Ccris 3801
34. Hsdb 254
35. Hydroperoxyde De Cumene [french]
36. Hydroperoxyde De Cumyle [french]
37. Idroperossido Di Cumene [italian]
38. Idroperossido Di Cumolo [italian]
39. Einecs 201-254-7
40. Rcra Waste No. U096
41. Alpha,alpha-dimethylbenzylhydroperoxide
42. Unii-pg7jd54x4i
43. Brn 1908117
44. Hydroperoxide, 1-methyl-1-phenylethyl-
45. Hyperiz
46. Hydroperoxide, Alpha,alpha-dimethylbenzyl-
47. Cumyl-hydroperoxide
48. Ph 80
49. Trigonox K 80
50. Trigonox K-95
51. Trigonox R 239a
52. Hydroperoxide, Alpha,alpha-dimethylbenzyl
53. Alpha-cumyl Hydroperoxide
54. Alpha-cumene Hydroperoxide
55. Dsstox_cid_4869
56. Luperox Cu 80
57. Trigonox K 90
58. Ec 201-254-7
59. .alpha.-cumyl Hydroperoxide
60. Chp-5
61. Dsstox_rid_77559
62. .alpha.-cumene Hydroperoxide
63. Dsstox_gsid_24869
64. Schembl15251
65. 4-06-00-03221 (beilstein Handbook Reference)
66. Chembl1518369
67. Schembl11210695
68. Chp-158
69. 2-phenylpropan-2-yl Hydroperoxide
70. Cumene Hydroperoxide [hsdb]
71. Zinc8585911
72. Tox21_300283
73. Mfcd00002129
74. Stl453641
75. Akos015841738
76. Ccg-207896
77. Un 2116
78. Cas-80-15-9
79. Ncgc00091748-01
80. Ncgc00091748-02
81. Ncgc00091748-03
82. Ncgc00254045-01
83. Cumene Hydroperoxide, Technical Grade, 80%
84. Cumene Hydroperoxide, Technical, ~80% In Cumene
85. Q414439
| Molecular Weight | 152.19 g/mol |
|---|---|
| Molecular Formula | C9H12O2 |
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 152.083729621 g/mol |
| Monoisotopic Mass | 152.083729621 g/mol |
| Topological Polar Surface Area | 29.5 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 115 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Oxidants
Electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION). (See all compounds classified as Oxidants.)
Liquid peroxides can be absorbed through the skin. /Organic peroxides/
Lefaux, R. Practical Toxicology of Plastics. Cleveland: CRC Press Inc., 1968., p. 166
Cumene hydroperoxide penetrates human red blood cells ... reduced by glutathione in the reaction catalyzed by glutathione peroxidase. Cumenol, water, and oxidized gluthathione were products.
PMID:4447610 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166284 Srivastava SK et al; Biochem J 139: 289-95 (1974)
Enzymatic reduction of cumene hydroperoxide leads to the formation of cumenol (2-phenylpropan-2-ol) in vitro.
PMID:4319399 Little CR et al; J Biol Chem 245 (14): 3632-6 (1970)
Cumene hydroperoxide has known human metabolites that include (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-(2-phenylpropan-2-ylperoxysulfanyl)propan-2-yl]amino]-5-oxopentanoic acid.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
The cumene hydroperoxide-hematin system reacts with 5,5-dimethyl-1-pyrroline-1-oxide to form the nitroxide 5,5-dimethyl-pyrrolidone-(2)-oxyl-(1) (DMPOX). DMPOX is formed via spin trapping of a cumene hydroperoxyl radical followed by an intramolecular carbanion displacement. Activation of carcinogen n-hydroxy-2-acetyl aminofluorene by cumene hydroperoxide-hematin system is most likely mediated by cumene hydroperoxyl radical.
PMID:6248759 Rosen GM, Rauckman EJ; Mol Pharmacol 17 (2): 233-8 (1980)
Cumene hydroperoxide oxidized cholesterol to the carcinogen 5,6-epoxide (5,6-alpha-epoxy-5-alpha-cholestan-3-beta-ol).
Smith LL, Kulig MJ; Cancer Biochem Biophys 1: 79-84 (1975)
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A Cumene hydroperoxide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cumene hydroperoxide, including repackagers and relabelers. The FDA regulates Cumene hydroperoxide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cumene hydroperoxide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Cumene hydroperoxide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Cumene hydroperoxide supplier is an individual or a company that provides Cumene hydroperoxide active pharmaceutical ingredient (API) or Cumene hydroperoxide finished formulations upon request. The Cumene hydroperoxide suppliers may include Cumene hydroperoxide API manufacturers, exporters, distributors and traders.
click here to find a list of Cumene hydroperoxide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Cumene hydroperoxide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Cumene hydroperoxide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cumene hydroperoxide GMP manufacturer or Cumene hydroperoxide GMP API supplier for your needs.
A Cumene hydroperoxide CoA (Certificate of Analysis) is a formal document that attests to Cumene hydroperoxide's compliance with Cumene hydroperoxide specifications and serves as a tool for batch-level quality control.
Cumene hydroperoxide CoA mostly includes findings from lab analyses of a specific batch. For each Cumene hydroperoxide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Cumene hydroperoxide may be tested according to a variety of international standards, such as European Pharmacopoeia (Cumene hydroperoxide EP), Cumene hydroperoxide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cumene hydroperoxide USP).
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