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Chemistry

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Also known as: Cyamepromazine, 3546-03-0, Tercian, Cianatil, Cyamemazin, Kyamepromazine
Molecular Formula
C19H21N3S
Molecular Weight
323.5  g/mol
InChI Key
SLFGIOIONGJGRT-UHFFFAOYSA-N
FDA UNII
A2JGV5CNU4

Cyamemazine
Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).
1 2D Structure

Cyamemazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile
2.1.2 InChI
InChI=1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
2.1.3 InChI Key
SLFGIOIONGJGRT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)C#N)CN(C)C
2.2 Other Identifiers
2.2.1 UNII
A2JGV5CNU4
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 10-(3-dimethylamino-2-methylpropyl)phenothiazine-2-carbonitrile

2. Cyamamazine

3. Cyamemazine Monohydrochloride

4. Cyamepromazine

2.3.2 Depositor-Supplied Synonyms

1. Cyamepromazine

2. 3546-03-0

3. Tercian

4. Cianatil

5. Cyamemazin

6. Kyamepromazine

7. Cyamemazine [inn]

8. Th 2602

9. Rp-7204

10. Kyamepromazin

11. 7204 Rp

12. Rp 7204

13. F.i. 6229

14. A2jgv5cnu4

15. 10-(3-(dimethylamino)-2-methylpropyl)phenothiazine-2-carbonitrile

16. 10-(3-(dimethylamino)-2-methylpropyl)-10h-phenothiazine-2-carbonitrile

17. 10-[3-(dimethylamino)-2-methylpropyl]-10h-phenothiazine-2-carbonitrile

18. 7204 R.e.

19. 10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile

20. Cyamemazine (inn)

21. Fl-6229

22. Th-2602

23. Cyamepromezine

24. Ciamatil

25. Phenothiazine-2-carbonitrile, 10-(3-(dimethylamino)-2-methylpropyl)-

26. 10h-phenothiazine-2-carbonitrile, 10-(3-(dimethylamino)-2-methylpropyl)-

27. Ciamemazina

28. Cyamemazinum

29. 10h-phenothiazine-2-carbonitrile, 10-[3-(dimethylamino)-2-methylpropyl]-

30. Cyamemazinum [inn-latin]

31. Ciamemazina [inn-spanish]

32. Einecs 222-594-2

33. Unii-a2jgv5cnu4

34. Brn 0093261

35. Fi 6229

36. 10-(3-dimethylamino-2-methylpropyl)phenothiazine-2-carbonitrile

37. Cyamemazine [mi]

38. Gtpl84

39. Cyamemazine [mart.]

40. Cyamemazine [who-dd]

41. 4-27-00-04111 (beilstein Handbook Reference)

42. Schembl143041

43. Chembl2104153

44. Bdbm86057

45. Cyamemazine, >=98% (hplc)

46. Dtxsid80863190

47. Chebi:135379

48. Bcp07169

49. Cas_62865

50. Nsc_62865

51. Pdsp1_001282

52. Pdsp2_001266

53. Th2602

54. Akos030254703

55. Db09000

56. Hy-14264

57. Cs-0002964

58. Ft-0665239

59. Ft-0665240

60. D07307

61. L001155

62. Sr-01000945035

63. Q3008033

64. Sr-01000945035-1

65. 2-cyano-10-(3-[dimethylamino]-2-methyl-propyl)-phenothiazine

66. 10-[3-(dimethylamino)-2-methylpropyl]-10h-phenothiazine-2-carbonitrile #

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 323.5 g/mol
Molecular Formula C19H21N3S
XLogP34.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass323.14561886 g/mol
Monoisotopic Mass323.14561886 g/mol
Topological Polar Surface Area55.6 Ų
Heavy Atom Count23
Formal Charge0
Complexity443
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

N - Nervous system

N05 - Psycholeptics

N05A - Antipsychotics

N05AA - Phenothiazines with aliphatic side-chain

N05AA06 - Cyamemazine


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Looking for 3546-03-0 / Cyamemazine API manufacturers, exporters & distributors?

Cyamemazine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cyamemazine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cyamemazine manufacturer or Cyamemazine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cyamemazine manufacturer or Cyamemazine supplier.

PharmaCompass also assists you with knowing the Cyamemazine API Price utilized in the formulation of products. Cyamemazine API Price is not always fixed or binding as the Cyamemazine Price is obtained through a variety of data sources. The Cyamemazine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cyamemazine

Synonyms

Cyamepromazine, 3546-03-0, Tercian, Cianatil, Cyamemazin, Kyamepromazine

Cas Number

3546-03-0

Unique Ingredient Identifier (UNII)

A2JGV5CNU4

About Cyamemazine

Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).

Cyamemazine Manufacturers

A Cyamemazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cyamemazine, including repackagers and relabelers. The FDA regulates Cyamemazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cyamemazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cyamemazine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cyamemazine Suppliers

A Cyamemazine supplier is an individual or a company that provides Cyamemazine active pharmaceutical ingredient (API) or Cyamemazine finished formulations upon request. The Cyamemazine suppliers may include Cyamemazine API manufacturers, exporters, distributors and traders.

click here to find a list of Cyamemazine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cyamemazine GMP

Cyamemazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cyamemazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cyamemazine GMP manufacturer or Cyamemazine GMP API supplier for your needs.

Cyamemazine CoA

A Cyamemazine CoA (Certificate of Analysis) is a formal document that attests to Cyamemazine's compliance with Cyamemazine specifications and serves as a tool for batch-level quality control.

Cyamemazine CoA mostly includes findings from lab analyses of a specific batch. For each Cyamemazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cyamemazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Cyamemazine EP), Cyamemazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cyamemazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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