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Chemistry

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Also known as: Cyclam, 295-37-4, 1,4,8,11-tetrazacyclotetradecane, Mfcd00005105, [14]anen4, Ep5az544vp
Molecular Formula
C10H24N4
Molecular Weight
200.32  g/mol
InChI Key
MDAXKAUIABOHTD-UHFFFAOYSA-N
FDA UNII
EP5AZ544VP

Cyclam
1 2D Structure

Cyclam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1,4,8,11-tetrazacyclotetradecane
2.1.2 InChI
InChI=1S/C10H24N4/c1-3-11-7-9-13-5-2-6-14-10-8-12-4-1/h11-14H,1-10H2
2.1.3 InChI Key
MDAXKAUIABOHTD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CNCCNCCCNCCNC1
2.2 Other Identifiers
2.2.1 UNII
EP5AZ544VP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cyclam

2. Cyclam Dihydroiodide

3. Cyclam Diperchlorate

4. Cyclam Monohydrobromide

5. Jm1498

2.3.2 Depositor-Supplied Synonyms

1. Cyclam

2. 295-37-4

3. 1,4,8,11-tetrazacyclotetradecane

4. Mfcd00005105

5. [14]anen4

6. Ep5az544vp

7. Chebi:37401

8. 1,4,8,11-tetraazacyclo-tetradecane

9. Nsc-180811

10. Ips2

11. Einecs 206-039-1

12. Nsc 180811

13. Jm 1498

14. Brn 0111811

15. 14-crown-4n4

16. Cyclam(1,4,8,11-tetraazacyclotetradecane)

17. Unii-ep5az544vp

18. Schembl33477

19. Cbdive_013909

20. 5-26-11-00027 (beilstein Handbook Reference)

21. Mls000069469

22. Chembl125150

23. 1,8,11-tetraazacyclotetradecane

24. Dtxsid30183698

25. Bcp05842

26. 1,4,8,11tetraaza-cyclotetradecane

27. Jm1498

28. Nsc180811

29. Stl333618

30. Zinc19942876

31. 1,4,8,11-tetraaza-cyclotetradecane

32. 1,4,8,11-tetra-aza Cyclotetradecane

33. Akos015854525

34. Am84902

35. Cs-w019774

36. Jm-1498

37. Ncgc00018136-01

38. Ncgc00018136-02

39. Ncgc00018136-03

40. As-19218

41. Smr000059059

42. Sy010380

43. Db-047596

44. Ft-0624146

45. T1597

46. 1,4,8,11-tetraazacyclotetradecane, 98% (gc)

47. A819951

48. Q-200078

49. Q1970333

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 200.32 g/mol
Molecular Formula C10H24N4
XLogP3-1.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass200.20009678 g/mol
Monoisotopic Mass200.20009678 g/mol
Topological Polar Surface Area48.1 Ų
Heavy Atom Count14
Formal Charge0
Complexity92.7
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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","customerCountry":"INDIA","quantity":"1140.00","actualQuantity":"1140","unit":"KGS","unitRateFc":"17.5","totalValueFC":"20116.6","currency":"USD","unitRateINR":"1475.1","date":"12-Jul-2024","totalValueINR":"1681569.23","totalValueInUsd":"20116.6","indian_port":"Bangalore Air","hs_no":"29122990","bill_no":"4465735","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"CIUDAD DEL CARMEN","supplierAddress":"CHEMIN DE LA PARFUMERIE5 CH-1214 VERNIER, SWITZERLAND","customerAddress":"PLOT NO.26,2ND CROSS,JIGANI"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721413800,"product":"CYCLAMAL TOCO(AROMATIC CHEMICAL)(FOR MFG OF FRAGRANCES COMPOUND)","address":"1-5 SEVEN WELLS STREET","city":"CHENNAI ,TAMILNADU","supplier":"I.F.F. NEDERLAND B.V","supplierCountry":"INDIA","foreign_port":"AMSTERDAM, SCHIPHOL","customer":"INTERNATIONAL FLAVORS AND FRAGRANCES","customerCountry":"INDIA","quantity":"760.00","actualQuantity":"760","unit":"KGS","unitRateFc":"21.8","totalValueFC":"18323.1","currency":"USD","unitRateINR":"2015.3","date":"20-Jul-2024","totalValueINR":"1531646.66","totalValueInUsd":"18323.1","indian_port":"Madras Air","hs_no":"29122990","bill_no":"4613377","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"AMSTERDAM, SCHIPHOL","supplierAddress":"ZEVENHEUVELENWEG 60 5048 AN TILBURGSDNFSDNF NL","customerAddress":"1-5 SEVEN WELLS STREET"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724265000,"product":"CYCLAMEN ALDEHYDE EXTRA","address":"PLOT NO.71, ABHINAV NAGAR CHS,BORI","city":"MUMBAI,MAHARASHTRA","supplier":"GIVAUDAN INTERNATIONAL SA","supplierCountry":"SINGAPORE","foreign_port":"ANTWERPEN","customer":"FRAGOMATRIX PERFUMES LLP","customerCountry":"INDIA","quantity":"3040.00","actualQuantity":"3040","unit":"KGS","unitRateFc":"16.1","totalValueFC":"49572.4","currency":"USD","unitRateINR":"1367.8","date":"22-Aug-2024","totalValueINR":"4158057.28","totalValueInUsd":"49572.4","indian_port":"Surat-EPZ\/SEZ","hs_no":"29122990","bill_no":"5183292","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SINGAPORE","selfForZScoreResived":"Pharma Grade","supplierPort":"ANTWERPEN","supplierAddress":"H, ESSERS LOMMEL KRISTALPARK F&B MARIE POPELINSTRAAT 50 LOMEL SDNF Belgium","customerAddress":"PLOT NO.71, ABHINAV NAGAR CHS,BORI"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727980200,"product":"SODIUM CYCLAMATE 626","address":"ADCOCK INGRAM PHARMA PRIVATE LIMITED","city":"BANGALORE","supplier":"ADCOCK INGRAM","supplierCountry":"SOUTH AFRICA","foreign_port":"DURBAN","customer":"ADCOCK INGRAM","customerCountry":"INDIA","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"122.7","totalValueFC":"365.1","currency":"ZAR","unitRateINR":"613.6","date":"04-Oct-2024","totalValueINR":"30680","totalValueInUsd":"365.1","indian_port":"Bangalore Air","hs_no":"29339990","bill_no":"5943053","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SOUTH AFRICA","selfForZScoreResived":"Pharma Grade","supplierPort":"DURBAN","supplierAddress":"1 NEW ROAD MIDRAND, 1685 SDNF SOUTH AFRICA","customerAddress":"ADCOCK INGRAM PHARMA PRIVATE LIMITED"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1729881000,"product":"CYCLAMEN ALDEHYDE EXTRA","address":"PLOT NO.26,2ND CROSS,JIGANI","city":"BANGALORE","supplier":"GIVAUDAN INTERNATIONAL SA","supplierCountry":"MEXICO","foreign_port":"MEXICO CITY","customer":"GIVAUDAN INDIA PRIVATE ","customerCountry":"INDIA","quantity":"760.00","actualQuantity":"760","unit":"KGS","unitRateFc":"17.5","totalValueFC":"13420.6","currency":"USD","unitRateINR":"1483.8","date":"26-Oct-2024","totalValueINR":"1127683.13","totalValueInUsd":"13420.6","indian_port":"Bangalore Air","hs_no":"29122990","bill_no":"6350267","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"MEXICO CITY","supplierAddress":"CHEMIN DE LA PARFUMERIE 5 CH-1214 VERNIER , SWITZERLAND","customerAddress":"PLOT NO.26,2ND CROSS,JIGANI"}]
05-Jan-2021
30-Nov-2024
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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ABOUT THIS PAGE

Cyclam Manufacturers

A Cyclam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cyclam, including repackagers and relabelers. The FDA regulates Cyclam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cyclam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Cyclam Suppliers

A Cyclam supplier is an individual or a company that provides Cyclam active pharmaceutical ingredient (API) or Cyclam finished formulations upon request. The Cyclam suppliers may include Cyclam API manufacturers, exporters, distributors and traders.

click here to find a list of Cyclam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cyclam USDMF

A Cyclam DMF (Drug Master File) is a document detailing the whole manufacturing process of Cyclam active pharmaceutical ingredient (API) in detail. Different forms of Cyclam DMFs exist exist since differing nations have different regulations, such as Cyclam USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Cyclam DMF submitted to regulatory agencies in the US is known as a USDMF. Cyclam USDMF includes data on Cyclam's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Cyclam USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Cyclam suppliers with USDMF on PharmaCompass.

Cyclam GMP

Cyclam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cyclam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cyclam GMP manufacturer or Cyclam GMP API supplier for your needs.

Cyclam CoA

A Cyclam CoA (Certificate of Analysis) is a formal document that attests to Cyclam's compliance with Cyclam specifications and serves as a tool for batch-level quality control.

Cyclam CoA mostly includes findings from lab analyses of a specific batch. For each Cyclam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cyclam may be tested according to a variety of international standards, such as European Pharmacopoeia (Cyclam EP), Cyclam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cyclam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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