Find Cyclofenil manufacturers, exporters & distributors on PharmaCompass

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Synopsis

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Chemistry

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Also known as: 2624-43-3, Ondogyne, Sexovid, Cyclofenyl, Cyclopenil, Cyclophenyl
Molecular Formula
C23H24O4
Molecular Weight
364.4  g/mol
InChI Key
GVOUFPWUYJWQSK-UHFFFAOYSA-N
FDA UNII
J468V64WZ1

Cyclofenil
A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE.
1 2D Structure

Cyclofenil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[4-[(4-acetyloxyphenyl)-cyclohexylidenemethyl]phenyl] acetate
2.1.2 InChI
InChI=1S/C23H24O4/c1-16(24)26-21-12-8-19(9-13-21)23(18-6-4-3-5-7-18)20-10-14-22(15-11-20)27-17(2)25/h8-15H,3-7H2,1-2H3
2.1.3 InChI Key
GVOUFPWUYJWQSK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=O)OC1=CC=C(C=C1)C(=C2CCCCC2)C3=CC=C(C=C3)OC(=O)C
2.2 Other Identifiers
2.2.1 UNII
J468V64WZ1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-((4-(acetyloxy)phenyl)cyclohexylidenemethyl)phenol Acetate

2. Cyclophenil

3. F 6066

4. F-6066

5. F6066

6. Ondogyne

2.3.2 Depositor-Supplied Synonyms

1. 2624-43-3

2. Ondogyne

3. Sexovid

4. Cyclofenyl

5. Cyclopenil

6. Cyclophenyl

7. Fertodur

8. Ondonid

9. Rehibin

10. Sanocrisin

11. Sexadieno

12. Sexovar

13. Oginex

14. Neoclym

15. Ici 48213

16. (cyclohexylidenemethylene)bis(4,1-phenylene) Diacetate

17. F 6066

18. 4,4'-(cyclohexylidenemethylene)diphenol Diacetate Ester

19. (cyclohexylidenemethylene)-bis(4,1-phenylene) Diacetate

20. H 3452

21. Cyclophenil

22. F-6066

23. Ici-48213

24. Nsc-86464

25. Bis(p-hydroxyphenyl)cyclohexyldienemethane Diacetate

26. [4-[(4-acetyloxyphenyl)-cyclohexylidenemethyl]phenyl] Acetate

27. J468v64wz1

28. Cfn

29. 4,4'-(cyclohexylidenemethylene)bisphenol 1,1'-diacetate

30. Ncgc00165767-02

31. Dsstox_cid_2866

32. Dsstox_rid_76764

33. Dsstox_gsid_22866

34. (cyclohexylidenemethylene)bis(4,1-phenylene)diacetate

35. Ciclofenilo

36. Cyclofenilum

37. Cyclofenilum [inn-latin]

38. Ciclofenilo [inn-spanish]

39. Nsc 86464

40. Cas-2624-43-3

41. Cyclofenil [inn:ban:dcf:jan]

42. Einecs 220-089-1

43. Brn 2014687

44. Unii-j468v64wz1

45. Ai3-52271

46. Phenol, 4-((4-(acetyloxy)phenyl)cyclohexylidenemethyl)-, Acetate

47. Sexovid (tn)

48. P-cresol, Diacetate

49. Bis-(p-hydroxyphenyl)-cyclohexylidenemethane Diacetate

50. Bis(p-acetoxyphenyl)cyclohexylidenemethane

51. Cyclofenil [mi]

52. Cyclofenil (jan/inn)

53. Cyclofenil [inn]

54. Cyclofenil [jan]

55. F6066

56. 4,4'-(cyclohexylidenmethylen)diphenyl Diacetat

57. Cyclofenil [mart.]

58. Cyclofenil [who-dd]

59. Nciopen2_009345

60. Schembl132246

61. Chembl141305

62. (cyclohexylidenemethanediyl)dibenzene-4,1-diyl Diacetate

63. Dtxsid4022866

64. Chebi:31446

65. Zinc608288

66. Bcp29796

67. Nsc86464

68. Tox21_112259

69. Bdbm50523931

70. S5393

71. Akos015900207

72. P-cresol, Alpha-cyclohexylidene-alpha-(p-hydroxyphenyl)-, Diacetate

73. Tox21_112259_1

74. Ccg-268218

75. Cs-w011816

76. Db13472

77. Hy-w011100

78. Ncgc00165767-01

79. Ncgc00165767-03

80. Ncgc00165767-04

81. Ac-22576

82. As-69834

83. Cyclofenil, >=98% (hplc), White Solid

84. Bis-(p-acetoxyphenyl)-cyclohexylidenemethane

85. Db-046909

86. B7564

87. C74360

88. D01281

89. 624c433

90. A877295

91. Cyclophenil; F 6066; F6066;f-6066;ondogyne

92. Q513583

93. Sr-01000944933

94. J-016345

95. Sr-01000944933-1

96. Brd-k68996996-001-01-7

97. 4-{[4-(acetyloxy)phenyl](cyclohexylidene)methyl}phenyl Acetate

98. Cyclofenil,4,4\'-(cyclohexylidenemethylene)bisphenol1,1\'-diacetate

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 364.4 g/mol
Molecular Formula C23H24O4
XLogP35.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass364.16745924 g/mol
Monoisotopic Mass364.16745924 g/mol
Topological Polar Surface Area52.6 Ų
Heavy Atom Count27
Formal Charge0
Complexity503
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Fertility Agents, Female

Compounds which increase the capacity to conceive in females. (See all compounds classified as Fertility Agents, Female.)


4.2 ATC Code

G - Genito urinary system and sex hormones

G03 - Sex hormones and modulators of the genital system

G03G - Gonadotropins and other ovulation stimulants

G03GB - Ovulation stimulants, synthetic

G03GB01 - Cyclofenil


ABOUT THIS PAGE

Cyclofenil Manufacturers

A Cyclofenil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cyclofenil, including repackagers and relabelers. The FDA regulates Cyclofenil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cyclofenil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cyclofenil manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cyclofenil Suppliers

A Cyclofenil supplier is an individual or a company that provides Cyclofenil active pharmaceutical ingredient (API) or Cyclofenil finished formulations upon request. The Cyclofenil suppliers may include Cyclofenil API manufacturers, exporters, distributors and traders.

click here to find a list of Cyclofenil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cyclofenil JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Cyclofenil Drug Master File in Japan (Cyclofenil JDMF) empowers Cyclofenil API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Cyclofenil JDMF during the approval evaluation for pharmaceutical products. At the time of Cyclofenil JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Cyclofenil suppliers with JDMF on PharmaCompass.

Cyclofenil GMP

Cyclofenil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cyclofenil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cyclofenil GMP manufacturer or Cyclofenil GMP API supplier for your needs.

Cyclofenil CoA

A Cyclofenil CoA (Certificate of Analysis) is a formal document that attests to Cyclofenil's compliance with Cyclofenil specifications and serves as a tool for batch-level quality control.

Cyclofenil CoA mostly includes findings from lab analyses of a specific batch. For each Cyclofenil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cyclofenil may be tested according to a variety of international standards, such as European Pharmacopoeia (Cyclofenil EP), Cyclofenil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cyclofenil USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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