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1. Cyclohexanols
1. 108-93-0
2. Cyclohexyl Alcohol
3. Hexahydrophenol
4. 1-cyclohexanol
5. Hydrophenol
6. Hydroxycyclohexane
7. Hexalin
8. Hydralin
9. Adronal
10. Naxol
11. Adronol
12. Anol
13. Cykloheksanol
14. Cicloesanolo
15. Phenol, Hexahydro-
16. Cicloesanolo [italian]
17. Cykloheksanol [polish]
18. Cyclohexanone Cyclohexanol Mixture
19. Cyclohexan-1-ol
20. Nsc 403656
21. Mfcd00003855
22. Chebi:18099
23. 8e7s519m3p
24. Nsc-403656
25. Cxl
26. Cyclohexanols
27. Dsstox_cid_1894
28. Dsstox_rid_76390
29. Dsstox_gsid_21894
30. Hydroxycyclohexane; Nsc 403656; Nsc 54711; Naxol; Phenol, Hexahydro-
31. Cas-108-93-0
32. Hsdb 61
33. Ccris 5896
34. Einecs 203-630-6
35. Brn 0906744
36. Cylcohexanol
37. Unii-8e7s519m3p
38. Ai3-00040
39. Cyclohexyl-alcohol
40. Cyclohexane, Hydroxy-
41. Bdbm5
42. Cyanomethylthioacetic Acid
43. Cyclohexanol [mi]
44. Bmse000431
45. Wln: L6tj Aq
46. Cyclohexanol [hsdb]
47. Ec 203-630-6
48. Schembl5545
49. 4-06-00-00020 (beilstein Handbook Reference)
50. Mls001055343
51. Bidd:er0291
52. Chembl32010
53. Cyclohexanol, P.a., 99.0%
54. Dtxsid4021894
55. Cyclohexanol, Analytical Standard
56. Hms3039k08
57. Zinc1532765
58. Tox21_201481
59. Tox21_302803
60. Bbl013186
61. Cyclohexanol, Reagentplus(r), 99%
62. Nsc403656
63. Stl163965
64. Akos000119038
65. Zinc100502981
66. Db03703
67. Rp10050
68. Ncgc00090982-01
69. Ncgc00090982-02
70. Ncgc00256434-01
71. Ncgc00259032-01
72. Smr000677941
73. Cyclohexanol, Puriss., >=99.0% (gc)
74. Cyclohexanol, Saj First Grade, >=95.0%
75. Db-040851
76. Cs-0017198
77. Cyclohexanol, Jis Special Grade, >=98.0%
78. Ft-0624192
79. Ft-0641073
80. Cyclohexanol, Vetec(tm) Reagent Grade, 98%
81. C00854
82. Q423282
83. Q-200903
84. F0001-0184
| Molecular Weight | 100.16 g/mol |
|---|---|
| Molecular Formula | C6H12O |
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 100.088815002 g/mol |
| Monoisotopic Mass | 100.088815002 g/mol |
| Topological Polar Surface Area | 20.2 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 46.1 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
The substance can be absorbed into the body by inhalation and by ingestion.
International Program on Chemical Safety/Commission of the European Communities; International Chemical Safety Card on Cyclohexanol (November 1998). Available from, as of May 20, 2010: https://www.inchem.org/pages/icsc.html
Animal expt ... In large doses ... /cyclohexanol/ is readily absorbed from the skin ... .
Browning, E. Toxicity and Metabolism of Industrial Solvents. New York: American Elsevier, 1965., p. 386
Following oral admin ... to rabbits, cmpd is excreted in urine in conjugation with sulfuric & glucuronic acids. Similar results were obtained when animals were subjected to repeated inhalation of cmpd.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4648
... Rabbits exposed to lowest concn ... 145 ppm cyclohexanol in air, showed no incr in conjugation of urinary sulfates but excreted 5 times normal amt glucuronic acid.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4648
... Incr in glucuronic acid in urine was paralleled by a decr in percentage of inorg sulfates. ... That the urinary sulfate ratio became normal when exposure ceased ... led ... to ... /conclusion/ that there was no prolonged retention in organism.
Browning, E. Toxicity and Metabolism of Industrial Solvents. New York: American Elsevier, 1965., p. 386
Cyclohexane was hydroxylated to cyclohexanol by rat liver microsomes in presence of NADPH & oxygen. Pretreatment with phenobarbital at 80 mg/kg/day ip stimulated activity 6-fold, while benzopyrene pretreatment at 20 mg/kg ip lowered cyclohexane hydroxylation.
PMID:4388853 ULLRICH V; HOPPE-SEYLER'S Z PHYSIOL CHEM 350 (3): 357 (1969)
Cyclohexanol was identified as the urinary metabolite after admin of cyclohexylamine hydrochloride to rats, rabbits, & guinea pigs (50-500 mg/kg, orally or ip) and humans (25 or 200 mg, orally).
PMID:4655821 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174231 RENWICK AG, RT WILLIAMS; BIOCHEM J 129 (4): 857 (1972)
Fed to rabbits, /cyclohexanol/ ... Is mostly excreted as the glucuronide conjugate (60% of the dose), but a small amt is oxidized further into trans-cyclohexane-1,2-diol (6%).
Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 222
Hepatic NAD-dependent alcohol dehydrogenase ... is responsible for metabolism of ... cyclohexanol ...
Testa, B. and P. Jenner. Drug Metabolism: Chemical & Biochemical Aspects. New York: Marcel Dekker, Inc., 1976., p. 310
For more Metabolism/Metabolites (Complete) data for Cyclohexanol (8 total), please visit the HSDB record page.
No reports found; [TDR, p. 430]
TDR - Ryan RP, Terry CE, Leffingwell SS (eds). Toxicology Desk Reference: The Toxic Exposure and Medical Monitoring Index, 5th Ed. Washington DC: Taylor & Francis, 1999., p. 430
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ABOUT THIS PAGE
A Cyclohexanol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cyclohexanol, including repackagers and relabelers. The FDA regulates Cyclohexanol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cyclohexanol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Cyclohexanol supplier is an individual or a company that provides Cyclohexanol active pharmaceutical ingredient (API) or Cyclohexanol finished formulations upon request. The Cyclohexanol suppliers may include Cyclohexanol API manufacturers, exporters, distributors and traders.
click here to find a list of Cyclohexanol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Cyclohexanol DMF (Drug Master File) is a document detailing the whole manufacturing process of Cyclohexanol active pharmaceutical ingredient (API) in detail. Different forms of Cyclohexanol DMFs exist exist since differing nations have different regulations, such as Cyclohexanol USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Cyclohexanol DMF submitted to regulatory agencies in the US is known as a USDMF. Cyclohexanol USDMF includes data on Cyclohexanol's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Cyclohexanol USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Cyclohexanol suppliers with USDMF on PharmaCompass.
Cyclohexanol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Cyclohexanol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cyclohexanol GMP manufacturer or Cyclohexanol GMP API supplier for your needs.
A Cyclohexanol CoA (Certificate of Analysis) is a formal document that attests to Cyclohexanol's compliance with Cyclohexanol specifications and serves as a tool for batch-level quality control.
Cyclohexanol CoA mostly includes findings from lab analyses of a specific batch. For each Cyclohexanol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Cyclohexanol may be tested according to a variety of international standards, such as European Pharmacopoeia (Cyclohexanol EP), Cyclohexanol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cyclohexanol USP).
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