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Chemistry

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Also known as: D-cycloserine, 68-41-7, Seromycin, Orientomycin, Oxamycin, Cyclo-d-serine
Molecular Formula
C3H6N2O2
Molecular Weight
102.09  g/mol
InChI Key
DYDCUQKUCUHJBH-UWTATZPHSA-N
FDA UNII
95IK5KI84Z

Cycloserine
Antibiotic substance produced by Streptomyces garyphalus.
1 2D Structure

Cycloserine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4R)-4-amino-1,2-oxazolidin-3-one
2.1.2 InChI
InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
2.1.3 InChI Key
DYDCUQKUCUHJBH-UWTATZPHSA-N
2.1.4 Canonical SMILES
C1C(C(=O)NO1)N
2.1.5 Isomeric SMILES
C1[C@H](C(=O)NO1)N
2.2 Other Identifiers
2.2.1 UNII
95IK5KI84Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. R-4-amino-3-isoxazolidinone

2. Seromycin

2.3.2 Depositor-Supplied Synonyms

1. D-cycloserine

2. 68-41-7

3. Seromycin

4. Orientomycin

5. Oxamycin

6. Cyclo-d-serine

7. Cyclorin

8. D-4-amino-3-isoxazolidinone

9. Cicloserina

10. Farmiserina

11. Miroseryn

12. Tisomycin

13. Wasserina

14. Closina

15. Cycloserinum

16. (+)-4-amino-3-isoxazolidinone

17. D-4-amino-3-isoxazolidone

18. Alpha-cycloserine

19. (4r)-4-amino-1,2-oxazolidin-3-one

20. Miroserina

21. Tebemicina

22. Novoserin

23. (r)-4-aminoisoxazolidin-3-one

24. (+)-cycloserine

25. Oxamicina

26. D-(+)-cycloserine

27. (4r)-4-aminoisoxazolidin-3-one

28. Pa 94

29. Cycloserin

30. Micoserina

31. Pa-94

32. (r)-4-amino-isoxazolidin-3-one

33. D-oxamycin

34. Ro-1-9213

35. D-cs

36. 3-isoxazolidinone, 4-amino-, (r)-

37. E-733-a

38. 3-isoxazolidinone, 4-amino-, (4r)-

39. D-4-amino-3-isossazolidone

40. Hsdb 3218

41. D-oxamicina

42. 3-isoxazolidinone, 4-amino-, D-

43. K-300

44. I-1431

45. 3-isoxazolidinone, 4-amino-, (+)-

46. Nsc 154851

47. Chebi:40009

48. Ai3-50153

49. D-cycloserine, Synthetic

50. Dcs

51. Chembl771

52. Sc-49088

53. 95ik5ki84z

54. Nsc-76029

55. Nsc-154851

56. Cas-68-41-7

57. Ncgc00016306-01

58. Oxamicina [italian]

59. Cicloserina [italian]

60. Dsstox_cid_2870

61. Dsstox_rid_76766

62. Dsstox_gsid_22870

63. Cycloserinum [inn-latin]

64. Cicloserina [inn-spanish]

65. Cycloserine, D-

66. Closerin

67. .alpha.-cycloserine

68. Mfcd00005353

69. (r)-cycloserine

70. Seromycin (tn)

71. Smr000058313

72. D-4-amino-3-isossazolidone [italian]

73. (r)-4-amino-3-isoxazolidone

74. R-(+)-cycloserine

75. (r)-4-amino-3-isoxazolidinone

76. (4r)-4-amino-3-isoxazolidinone

77. Cycloserine (d)

78. Sr-01000075432

79. Drg-0195

80. (r)-(+)-cycloserine

81. Einecs 200-688-4

82. D-amino-3-isoxazolidinone

83. Brn 0080798

84. Unii-95ik5ki84z

85. Cycloserine-(d)

86. Serine, Cyclo-

87. 3-isoxazolidinone, 4-amino-, D

88. R(+)-4-amino-3-isoxazolidinone

89. Cycloserine [usp:inn:ban:jan]

90. 4ax

91. 3-isoxazolidinone, 4-amino-, (r)

92. (r)-(+)-4-amino-3-isoxazolidinone

93. Cycloserine, D(+)

94. D-cycloserine, Powder

95. Spectrum_000860

96. 1pb9

97. Cycloserine [mi]

98. Prestwick0_001089

99. Prestwick1_001089

100. Prestwick2_001089

101. Prestwick3_001089

102. Spectrum2_000084

103. Spectrum3_000371

104. Spectrum4_000305

105. Spectrum5_000797

106. Cycloserine [inn]

107. Cycloserine [jan]

108. Lopac-c-1159

109. Lopac-c-3909

110. Lopac-c-7005

111. Cycloserine [hsdb]

112. 3-isoxazolidinone, 4-amino-, (4r)- (9ci)

113. C 3909

114. C-9390

115. C-9400

116. Cycloserine [vandf]

117. Cycloserine [mart.]

118. Lopac0_000252

119. Schembl34322

120. Bspbio_001138

121. Bspbio_002121

122. Cycloserine [who-dd]

123. Cycloserine [who-ip]

124. Kbiogr_000890

125. Kbioss_001340

126. 4-27-00-05549 (beilstein Handbook Reference)

127. Mls000758215

128. Mls001423962

129. Mls002548887

130. Bidd:gt0707

131. D-cycloserine Synth. Bp 88

132. Divk1c_000098

133. Spectrum1500215

134. Spbio_000008

135. Spbio_003029

136. Bpbio1_001252

137. Fa6c7f8b-d080-4ea3-978f-1ecfb5a29d09

138. Gtpl9489

139. Cycloserine (jp17/usp/inn)

140. 4-amino-3-isoxazolidinone, D-

141. Dtxsid8022870

142. Hms500e20

143. Kbio1_000098

144. Kbio2_001340

145. Kbio2_003908

146. Kbio2_006476

147. Kbio3_001341

148. Cycloserine [orange Book]

149. Ninds_000098

150. Cycloserine [usp Impurity]

151. Hms1571i20

152. Hms1920c06

153. Hms2051c15

154. Hms2091i14

155. Hms2098i20

156. Hms2232f03

157. Hms3259l19

158. Hms3260d06

159. Hms3715i14

160. Nj-21

161. Pharmakon1600-01500215

162. Cycloserine [usp Monograph]

163. (r)-3-isoxazolidinone, 4-amino-

164. 4-amino-3-isoxazolidinone, (r)-

165. Act04767

166. Cycloserinum [who-ip Latin]

167. Hy-b0030

168. Tox21_110361

169. Tox21_500252

170. Bdbm50038178

171. Bdbm50103516

172. Ccg-39705

173. D-cycloserine, >=96.0% (nt)

174. Lmpk14000007

175. Nsc756712

176. S1998

177. Zinc34676245

178. 4-isoxazolidinamine, 3-oxo-, (d)-

179. Akos015994626

180. Tox21_110361_1

181. Ac-4721

182. Db00260

183. Hs-0079

184. Lp00252

185. Nc00050

186. Nc00676

187. Nsc-756712

188. Sdccgsbi-0050240.p005

189. Idi1_000098

190. Smp1_000167

191. Ncgc00015213-01

192. Ncgc00015213-02

193. Ncgc00015213-03

194. Ncgc00016306-02

195. Ncgc00016306-03

196. Ncgc00016306-04

197. Ncgc00016306-05

198. Ncgc00016306-07

199. Ncgc00016306-08

200. Ncgc00016306-17

201. Ncgc00093713-01

202. Ncgc00093713-02

203. Ncgc00260937-01

204. Cas-339-72-0

205. Sbi-0050240.p004

206. Ab00443920

207. Eu-0100252

208. 3-isoxazolidinone, 4-amino-, (+)- (8ci)

209. C08057

210. D00877

211. Ab00443920_09

212. Ab00443920_10

213. 005c353

214. A836140

215. Q418508

216. Sr-01000759389

217. Sr-01000075432-1

218. Sr-01000075432-2

219. Sr-01000075432-5

220. Sr-01000075432-9

221. Sr-01000759389-4

222. Sr-01000075432-10

223. F2173-1228

224. Z1522567171

225. Cycloserine, United States Pharmacopeia (usp) Reference Standard

226. Cycloserine, Pharmaceutical Secondary Standard; Certified Reference Material

227. (4r)-4-azaniumyl-4,5-dihydroisoxazol-3-olate;(r)-4-aminoisoxazolidin-3-one

2.4 Create Date
2005-06-01
3 Chemical and Physical Properties
Molecular Weight 102.09 g/mol
Molecular Formula C3H6N2O2
XLogP3-1.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass102.042927438 g/mol
Monoisotopic Mass102.042927438 g/mol
Topological Polar Surface Area64.4 Ų
Heavy Atom Count7
Formal Charge0
Complexity92.9
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameSeromycin
PubMed HealthCycloserine (By mouth)
Drug ClassesAntitubercular
Drug LabelSeromycin(Cycloserine Capsules, USP), 3-isoxazolidinone, 4-amino, (R)is a broadspectrum antibiotic that is produced by a strain of Streptomyces orchidaceus and has also been synthesized. Cycloserine is a white to offwhite powder that is soluble in wa...
Active IngredientCycloserine
Dosage FormCapsule
RouteOral
Strength250mg
Market StatusPrescription
CompanyPurdue Gmp

2 of 2  
Drug NameSeromycin
PubMed HealthCycloserine (By mouth)
Drug ClassesAntitubercular
Drug LabelSeromycin(Cycloserine Capsules, USP), 3-isoxazolidinone, 4-amino, (R)is a broadspectrum antibiotic that is produced by a strain of Streptomyces orchidaceus and has also been synthesized. Cycloserine is a white to offwhite powder that is soluble in wa...
Active IngredientCycloserine
Dosage FormCapsule
RouteOral
Strength250mg
Market StatusPrescription
CompanyPurdue Gmp

4.2 Therapeutic Uses

Anti-Infective Agents, Urinary; Antibiotics, Antitubercular; Antimetabolites

National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)


INHIBITS WIDE VARIETY OF BOTH GRAM-POSITIVE & GRAM-NEGATIVE BACTERIA, INCL MYCOBACTERIA. ... IT HAS BEEN USED SUCCESSFULLY AGAINST STUBBORN URINARY TRACT INFECTIONS CAUSED BY STREPTOCOCCI, STAPHYLOCOCCI, E COLI & AEROBACTER AEROGENES.

Osol, A. and J.E. Hoover, et al. (eds.). Remington's Pharmaceutical Sciences. 15th ed. Easton, Pennsylvania: Mack Publishing Co., 1975., p. 1146


Cycloserine is indicated in combination with other antituberculars in the treatment of tuberculosis after failure of the primary medications (pyrazinamide, streptomycin, isoniazid, rifampin, and ethambutol). /Included in US product labeling/

USP Convention. USPDI - Drug Information for the Health Care Professional. 16th ed. Volume I. Rockville, MD: U.S. Pharmaceutical Convention, Inc. 1996 (Plus updates)., p. 1130


Cycloserine is used in the treatment of atypical mycobacterial infections, such as mycobacterium avium complex. /NOT included in US product labeling/

USP Convention. USPDI - Drug Information for the Health Care Professional. 16th ed. Volume I. Rockville, MD: U.S. Pharmaceutical Convention, Inc. 1996 (Plus updates)., p. 1130


For more Therapeutic Uses (Complete) data for CYCLOSERINE (6 total), please visit the HSDB record page.


4.3 Drug Warning

PATIENTS WITH HISTORY OF MENTAL ILLNESS OFTEN TOLERATE CYCLOSERINE UNUSUALLY WELL, WHEREAS APPARENTLY STABLE INDIVIDUALS MAY DEVELOP PSYCHOTIC REACTION SOON AFTER INITIATION OF TREATMENT, SOMETIMES BEFORE THERAPEUTIC SERUM LEVELS ARE ACHIEVED.

American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 1641


Maternal Medication usually Compatible with Breast-Feeding: Cycloserine: Reported Sign or Symptom in Infant or Effect on Lactation: None. /from Table 6/

Report of the American Academy of Pediatrics Committee on Drugs in Pediatrics 93 (1): 140 (1994)


The drug may accumulate to toxic concentrations in patients with renal insufficiency; it may be removed from the circulation by dialysis.

Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1165


Because cycloserine is renally excreted, cycloserine may accumulate in patients with renal function impairment, leading to an increased risk of side effects; the medication should not be given to patients with renal function impairment (creatinine clearance of < 50 ml per minute (0.83 ml per second)).

USP Convention. USPDI - Drug Information for the Health Care Professional. 16th ed. Volume I. Rockville, MD: U.S. Pharmaceutical Convention, Inc. 1996 (Plus updates)., p. 1131


For more Drug Warnings (Complete) data for CYCLOSERINE (10 total), please visit the HSDB record page.


4.4 Drug Indication

Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).


5 Pharmacology and Biochemistry
5.1 Pharmacology

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria


5.2 MeSH Pharmacological Classification

Anti-Infective Agents, Urinary

Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. (See all compounds classified as Anti-Infective Agents, Urinary.)


Antimetabolites

Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033) (See all compounds classified as Antimetabolites.)


Antibiotics, Antitubercular

Substances obtained from various species of microorganisms that are, alone or in combination with other agents, of use in treating various forms of tuberculosis; most of these agents are merely bacteriostatic, induce resistance in the organisms, and may be toxic. (See all compounds classified as Antibiotics, Antitubercular.)


5.3 ATC Code

J - Antiinfectives for systemic use

J04 - Antimycobacterials

J04A - Drugs for treatment of tuberculosis

J04AB - Antibiotics

J04AB01 - Cycloserine


5.4 Absorption, Distribution and Excretion

Absorption

Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.


VALUE OF CYCLOSERINE IS ENHANCED BY FACT THAT IT DIFFUSES INTO CELLS & CROSSES BLOOD-BRAIN BARRIER, EVEN IN ABSENCE OF DISEASE.

American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 1641


When given orally, 70% to 90% of cycloserine is rapidly absorbed. Peak concentrations in plasma are reached 3 to 4 hours after a single dose and are in the range of 20 to 35 ug/ml in children who receive 20 mg/kg; only small quantities are present after 12 hours.

Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1165


Cycloserine is distributed throughout body fluids and tissues. There is no appreciable blood-brain barrier to the drug, and CSF concentrations in all patients are approximately the same as those in plasma. About 50% of a parenteral dose of cycloserine is excreted unchanged in the urine in the first 12 hours; a total of 65% is recoverable in the active form over a period of 72 hours.

Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1165


5.5 Metabolism/Metabolites

APPROX 35% OF ANTIBIOTIC IS METABOLIZED TO AS-YET-UNIDENTIFIED SUBSTANCE.

Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 1211


5.6 Biological Half-Life

Half-life in patients with normal renal function is 10 hours, and is prolonged in patients with impaired renal function.


Normal renal function - 10 hours. Impaired renal function - prolonged.

USP Convention. USPDI - Drug Information for the Health Care Professional. 16th ed. Volume I. Rockville, MD: U.S. Pharmaceutical Convention, Inc. 1996 (Plus updates)., p. 1131


5.7 Mechanism of Action

Cycloserine is an analog of the amino acid D-alanine. It interferes with an early step in bacterial cell wall synthesis in the cytoplasm by competitive inhibition of two enzymes, L-alanine racemase, which forms D-alanine from L-alanine, and D-alanylalanine synthetase, which incorporates D-alanine into the pentapeptide necessary for peptidoglycan formation and bacterial cell wall synthesis.


EXCRETION OF B-ALANINE & D-BETA-AMINOISOBUTYRIC ACID WAS INCR IN PT WITH TUBERCULOSIS RECEIVING CLINICAL DOSES OF D-CYCLOSERINE.

YASUMITSU T ET AL; BIOCHEM PHARMACOL 25(3) 253-8 (1976)


Cycloserine is inhibitory for Mycobacterium tuberculosis in concentrations of 5 to 20 ug/ml in vitro. There is no cross-resistance between cycloserine and other tuberculostatic agents. While the antibiotic is effective in experimental infections caused by other microorganisms, studies in vitro reveal no suppression of growth in cultures made in conventional media, which contain D-alanine; this amino acid blocks the antibacterial activity of cycloserine. ... Cycloserine inhibits reactions in which D-alanine is involved in bacterial cell-wall synthesis. The use of media free of D-alanine reveals that the antibiotic inhibits the growth in vitro of enterococci, E. coli, Staph. aureus, Nocardia species, and Chlamydia.

Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1165


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08-Jan-2021
22-Oct-2024
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Cycloserine Manufacturers

A Cycloserine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cycloserine, including repackagers and relabelers. The FDA regulates Cycloserine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cycloserine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cycloserine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cycloserine Suppliers

A Cycloserine supplier is an individual or a company that provides Cycloserine active pharmaceutical ingredient (API) or Cycloserine finished formulations upon request. The Cycloserine suppliers may include Cycloserine API manufacturers, exporters, distributors and traders.

click here to find a list of Cycloserine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cycloserine USDMF

A Cycloserine DMF (Drug Master File) is a document detailing the whole manufacturing process of Cycloserine active pharmaceutical ingredient (API) in detail. Different forms of Cycloserine DMFs exist exist since differing nations have different regulations, such as Cycloserine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Cycloserine DMF submitted to regulatory agencies in the US is known as a USDMF. Cycloserine USDMF includes data on Cycloserine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Cycloserine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Cycloserine suppliers with USDMF on PharmaCompass.

Cycloserine KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Cycloserine Drug Master File in Korea (Cycloserine KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Cycloserine. The MFDS reviews the Cycloserine KDMF as part of the drug registration process and uses the information provided in the Cycloserine KDMF to evaluate the safety and efficacy of the drug.

After submitting a Cycloserine KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Cycloserine API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Cycloserine suppliers with KDMF on PharmaCompass.

Cycloserine WC

A Cycloserine written confirmation (Cycloserine WC) is an official document issued by a regulatory agency to a Cycloserine manufacturer, verifying that the manufacturing facility of a Cycloserine active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Cycloserine APIs or Cycloserine finished pharmaceutical products to another nation, regulatory agencies frequently require a Cycloserine WC (written confirmation) as part of the regulatory process.

click here to find a list of Cycloserine suppliers with Written Confirmation (WC) on PharmaCompass.

Cycloserine NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Cycloserine as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Cycloserine API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Cycloserine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Cycloserine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Cycloserine NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Cycloserine suppliers with NDC on PharmaCompass.

Cycloserine GMP

Cycloserine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cycloserine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cycloserine GMP manufacturer or Cycloserine GMP API supplier for your needs.

Cycloserine CoA

A Cycloserine CoA (Certificate of Analysis) is a formal document that attests to Cycloserine's compliance with Cycloserine specifications and serves as a tool for batch-level quality control.

Cycloserine CoA mostly includes findings from lab analyses of a specific batch. For each Cycloserine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cycloserine may be tested according to a variety of international standards, such as European Pharmacopoeia (Cycloserine EP), Cycloserine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cycloserine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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