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ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 Listed Suppliers, $ API Reference Price

1 API Suppliers
1 Listed Suppliers
$ API Reference Price

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 139

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FDF

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Chemistry

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Also known as: 328-38-1, H-d-leu-oh, (2r)-2-amino-4-methylpentanoic acid, (r)-leucine, Leucine, d-, (r)-(-)-leucine

Molecular Formula

C₆H₁₃NO₂

Molecular Weight

131.17 g/mol

InChI Key

ROHFNLRQFUQHCH-RXMQYKEDSA-N

FDA UNII

965COD96YA

1 2D Structure

D-Leucine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R)-2-amino-4-methylpentanoic acid

2.1.2 InChI

InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1

2.1.3 InChI Key

ROHFNLRQFUQHCH-RXMQYKEDSA-N

2.1.4 Canonical SMILES

CC(C)CC(C(=O)O)N

2.1.5 Isomeric SMILES

CC(C)C[C@H](C(=O)O)N

2.2 Other Identifiers

2.2.1 UNII

965COD96YA

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 328-38-1

2. H-d-leu-oh

3. (2r)-2-amino-4-methylpentanoic Acid

4. (r)-leucine

5. Leucine, D-

6. (r)-(-)-leucine

7. (r)-2-amino-4-methylpentanoic Acid

8. D-homo-valine

9. D-2-amino-4-methylvaleric Acid

10. D-leu

11. D-leucin

12. D-leuzin

13. Chebi:28225

14. (2r)-2-azaniumyl-4-methylpentanoate

15. 965cod96ya

16. Ncgc00163335-01

17. Dsstox_cid_26347

18. Dsstox_rid_81551

19. Dsstox_gsid_46347

20. Dle

21. Leucine,d

22. Mfcd00063088

23. Cas-328-38-1

24. Unii-965cod96ya

25. Nsc-77687

26. D-2-amino-4-methylpentanoic Acid

27. (d)-leucine

28. Einecs 206-327-7

29. Nsc 77687

30. D-leu42

31. Ai3-52422

32. Schembl42012

33. D-leucineleucine, D-

34. Chembl1232258

35. Dtxsid6046347

36. Zinc388396

37. (r)-2-amino-4-methylvaleric Acid

38. Act04820

39. Bcp30475

40. Cs-d1369

41. D-leucine, Reagentplus(r), 99%

42. Hy-y0378

43. Tox21_112049

44. Bdbm50463213

45. (r)-2-amino-4-methyl-pentanoic Acid

46. Akos015841823

47. Tox21_112049_1

48. Ac-8658

49. Am81870

50. Db01746

51. (2r)-2-amino-4-methyl-pentanoic Acid

52. Ncgc00013565-03

53. Ncgc00163335-02

54. Ncgc00163335-03

55. As-12286

56. D-leucine, Vetec(tm) Reagent Grade, 97%

57. (r)-4-methyl-2-aminopentanoic Acid

58. L0027

59. C01570

60. Q16081973

61. F1905-7150

62. Z966690616

63. D-2-amino-4-methylpentanoic Acid;(r)-leucine;h-d-leu-oh

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₆H₁₃NO₂
Molecular Weight	131.17 g/mol
XLogP3	-1.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	131.094628657 g/mol
Monoisotopic Mass	131.094628657 g/mol
Topological Polar Surface Area	63.3 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	101
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

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Listed Suppliers

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API Reference Price

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PADRA, DIST. BARODA,GUJARAT","supplier":"HIGHPHARM MEDCHEM CO. ","supplierCountry":"CHINA","foreign_port":"CHENGDU","customer":"APOTHECON PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"650","totalValueFC":"1313.5","currency":"USD","unitRateINR":"48945","date":"15-Jul-2021","totalValueINR":"97890","totalValueInUsd":"1313.5","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"4684522","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"CHENGDU","supplierAddress":"","customerAddress":"PLOT NO. 1143\/B,AA44\/A&1144\/B,PADRA JAMBUSAR RD, AT VILLAGE DABHASA"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1633631400,"product":"N-ACETYL-D-LEUCINE [BATCH NO. H8011-210901]","address":"TheGalleriaDLFMayurviharUnit236237 MayurPlaceMayurViharP1Extn Contact","city":"NEW DELHI","supplier":"GILEAD SCIENCES","supplierCountry":"CHINA","foreign_port":"NA","customer":"SRF LIMITED","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"146.1","totalValueFC":"44297.1","currency":"USD","unitRateINR":"11061.3","date":"08-Oct-2021","totalValueINR":"3318385.2","totalValueInUsd":"44297.1","indian_port":"DELHI AIR","hs_no":"29241900","bill_no":"5761772","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"TheGalleriaDLFMayurviharUnit236237 MayurPlaceMayurViharP1Extn Contact"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1639420200,"product":"N-ACETYL-D-LEUCINE","address":"7-2-A2, HETERO CORPORATE, INDUSTRIAL ESTATE, SANATHNAGAR, Con","city":"HYDERABAD","supplier":"ANGENE INTERNATIONAL LTD,","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"HETERO DRUGS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"560","totalValueFC":"281.8","currency":"USD","unitRateINR":"42504","date":"14-Dec-2021","totalValueINR":"21252","totalValueInUsd":"281.8","indian_port":"MADRAS AIR","hs_no":"29339990","bill_no":"6670221","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"","customerAddress":"7-2-A2, HETERO CORPORATE, INDUSTRIAL ESTATE, SANATHNAGAR, Con"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1649961000,"product":"D-LEUCINE (NOT FOR MEDICINAL USE)","address":"NO.52, SIDCO INDUSTRIAL ESTATE, ALATHUR, THIRUPPORUR","city":"TAMILNADU","supplier":"NINGBO HI-TECH BIOCHEMICALS","supplierCountry":"CHINA","foreign_port":"NA","customer":"S.V.CHEM INTERMEDIATES PRIVATE LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"230","totalValueFC":"1170.6","currency":"USD","unitRateINR":"17664","date":"15-Apr-2022","totalValueINR":"88320","totalValueInUsd":"1170.6","indian_port":"MADRAS SEA","hs_no":"29224290","bill_no":"8285054","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Non Pharma","supplierPort":"NA","supplierAddress":"","customerAddress":"NO.52, SIDCO INDUSTRIAL ESTATE, ALATHUR, THIRUPPORUR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655749800,"product":"N-ACETYL-D-LEUCINE","address":"Part of Plot No.11 & 87, Sy No.119 Phase - 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PU DONG","customer":"SRF LIMITED","customerCountry":"INDIA","quantity":"3100.00","actualQuantity":"3100","unit":"KGS","unitRateFc":"116.5","totalValueFC":"365464.6","currency":"USD","unitRateINR":"9826.8","date":"28-May-2024","totalValueINR":"30463002.5","totalValueInUsd":"365464.6","indian_port":"Bombay Air","hs_no":"29241900","bill_no":"3704766","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"ROOM 501 BUILDING 9TH NO. 6 JINMAROAD MAQUN QIXIA NANJING JIANGSU210049 CHINA","customerAddress":"C-8 COMMERCIAL COMPLEX"}]

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API Import of D-Leucine obtained from Indian Customs Trade Statistics

D-Leucine

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ACTIVE PHARMA INGREDIENTS

1 API Suppliers

1 Listed Suppliers

$ API Reference Price

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 139

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

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