Find D-Phenylalanine API manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 673-06-3, H-d-phe-oh, (2r)-2-amino-3-phenylpropanoic acid, Phenylalanine d-form, Sabiden, D-phe
Molecular Formula
C9H11NO2
Molecular Weight
165.19  g/mol
InChI Key
COLNVLDHVKWLRT-MRVPVSSYSA-N
FDA UNII
032K16VRCU

D-Phenylalanine API
D-Phenylalanine is the synthetic dextro isomer of phenylalanine, an essential amino acid with anti-depressant and analgesic activities. D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters. As a result this agent is associated with elevated levels of the neurotransmitters dopamine and norepinephrine in the brain, which may alleviate symptoms of depression. In addition, as an inhibitor of enkephalinase, which metabolizes endorphins, D-phenylalanine may be used to treat chronic pain through blocking the break down of endorphins (natural pain killers).
1 2D Structure

D-Phenylalanine API

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R)-2-amino-3-phenylpropanoic acid
2.1.2 InChI
InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
2.1.3 InChI Key
COLNVLDHVKWLRT-MRVPVSSYSA-N
2.1.4 Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)O)N
2.1.5 Isomeric SMILES
C1=CC=C(C=C1)C[C@H](C(=O)O)N
2.2 Other Identifiers
2.2.1 UNII
032K16VRCU
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 673-06-3

2. H-d-phe-oh

3. (2r)-2-amino-3-phenylpropanoic Acid

4. Phenylalanine D-form

5. Sabiden

6. D-phe

7. Alanine, Phenyl-, D-

8. (r)-2-amino-3-phenylpropanoic Acid

9. Nci-c60195

10. Phenylalanine,d-

11. D-alpha-amino-beta-phenylpropionic Acid

12. D-(+)-phenylalanine

13. (r)-2-amino-3-phenylpropionic Acid

14. 032k16vrcu

15. Chebi:16998

16. Mfcd00004270

17. D-.beta.-phenylalanine

18. Ccris 6267

19. Einecs 211-603-5

20. Nsc 25005

21. Unii-032k16vrcu

22. Nsc-25005

23. Dphe

24. L-3-phenylalanine

25. Hdpheoh

26. (d)-phenylalanine

27. Phenylalanine,(s)

28. Spectrum_001725

29. Spectrum2_001558

30. Spectrum4_000865

31. Spectrum5_001137

32. (r)-phenylalanine

33. Phenylalanine, D-

34. D-phenylalanine, >=99%

35. Schembl92744

36. Kbiogr_001529

37. Kbioss_002205

38. Divk1c_000453

39. Spectrum1503391

40. Spbio_001436

41. Chembl379630

42. Gtpl5797

43. Zinc1927

44. Dtxsid4025876

45. Bdbm36161

46. Hms501g15

47. Kbio1_000453

48. Kbio2_002205

49. Kbio2_004773

50. Kbio2_007341

51. D-phenylalanine [who-dd]

52. D-.beta.-phenyl-.alpha.-alanine

53. Ninds_000453

54. Phenylalanine D-form [mi]

55. Hms1922c08

56. Pharmakon1600-01503391

57. Act08578

58. Hy-y0079

59. D-phenylalanine, >=98% (hplc)

60. Ccg-39336

61. Nsc758460

62. S4153

63. Akos007930513

64. Ac-8664

65. Am83526

66. Cs-w020009

67. Db02556

68. Nsc-758460

69. Idi1_000453

70. Ncgc00163338-01

71. Ncgc00163338-03

72. Ac-11292

73. As-11997

74. Sbi-0051820.p002

75. P0135

76. En300-60166

77. 73p063

78. A20666

79. C02265

80. M02934

81. Ab00052351_02

82. Ab00052351_03

83. Sr-01000872765

84. D-phenylalanine, Vetec(tm) Reagent Grade, >=98%

85. J-300203

86. Q-101646

87. Sr-01000872765-1

88. Q26841253

89. Z1696844707

90. 4c53b247-2fe4-4464-92c0-9f3782a08966

91. D-alpha-amino-beta-phenylpropionic Acid;d-beta-phenyl-alpha-aminopropionic Acid

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 165.19 g/mol
Molecular Formula C9H11NO2
XLogP3-1.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass165.078978594 g/mol
Monoisotopic Mass165.078978594 g/mol
Topological Polar Surface Area63.3 Ų
Heavy Atom Count12
Formal Charge0
Complexity153
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

D-Phenylalanine API Manufacturers

A D-Phenylalanine API manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of D-Phenylalanine API, including repackagers and relabelers. The FDA regulates D-Phenylalanine API manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. D-Phenylalanine API API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of D-Phenylalanine API manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

D-Phenylalanine API Suppliers

A D-Phenylalanine API supplier is an individual or a company that provides D-Phenylalanine API active pharmaceutical ingredient (API) or D-Phenylalanine API finished formulations upon request. The D-Phenylalanine API suppliers may include D-Phenylalanine API API manufacturers, exporters, distributors and traders.

click here to find a list of D-Phenylalanine API suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

D-Phenylalanine API USDMF

A D-Phenylalanine API DMF (Drug Master File) is a document detailing the whole manufacturing process of D-Phenylalanine API active pharmaceutical ingredient (API) in detail. Different forms of D-Phenylalanine API DMFs exist exist since differing nations have different regulations, such as D-Phenylalanine API USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A D-Phenylalanine API DMF submitted to regulatory agencies in the US is known as a USDMF. D-Phenylalanine API USDMF includes data on D-Phenylalanine API's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The D-Phenylalanine API USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of D-Phenylalanine API suppliers with USDMF on PharmaCompass.

D-Phenylalanine API GMP

D-Phenylalanine API Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of D-Phenylalanine API GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right D-Phenylalanine API GMP manufacturer or D-Phenylalanine API GMP API supplier for your needs.

D-Phenylalanine API CoA

A D-Phenylalanine API CoA (Certificate of Analysis) is a formal document that attests to D-Phenylalanine API's compliance with D-Phenylalanine API specifications and serves as a tool for batch-level quality control.

D-Phenylalanine API CoA mostly includes findings from lab analyses of a specific batch. For each D-Phenylalanine API CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

D-Phenylalanine API may be tested according to a variety of international standards, such as European Pharmacopoeia (D-Phenylalanine API EP), D-Phenylalanine API JP (Japanese Pharmacopeia) and the US Pharmacopoeia (D-Phenylalanine API USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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