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    Also known as: Dabigatran etexilate mesylate, 872728-81-9, Pradaxa, Ethyl 3-[[2-[[4-[(z)-n'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic acid, Dtxsid20236248, Ex-a1966
    Molecular Formula
    C35H45N7O8S
    Molecular Weight
    723.8  g/mol
    InChI Key
    XETBXHPXHHOLOE-UHFFFAOYSA-N
    Dabigatran Etexilate Mesylate
    A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.
    1 2D Structure

    Dabigatran Etexilate Mesylate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    ethyl 3-[[2-[[4-[(Z)-N'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic acid
    2.1.2 InChI
    InChI=1S/C34H41N7O5.CH4O3S/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43)41(20-18-31(42)45-5-2)29-11-8-9-19-36-29;1-5(2,3)4/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44);1H3,(H,2,3,4)
    2.1.3 InChI Key
    XETBXHPXHHOLOE-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCCCCCOC(=O)N=C(C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)N.CS(=O)(=O)O
    2.1.5 Isomeric SMILES
    CCCCCCOC(=O)/N=C(/C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)\N.CS(=O)(=O)O
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Bibr 1048

    2. Dabigatran

    3. Dabigatran Etexilate

    4. Dabigatran Etexilate Mesylate

    5. Etexilate Mesylate, Dabigatran

    6. Etexilate, Dabigatran

    7. Mesylate, Dabigatran Etexilate

    8. N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1h-benzimidazol-5-yl)carbonyl)-n-2-pyridinyl-beta-alanine

    9. Pradaxa

    2.2.2 Depositor-Supplied Synonyms

    1. Dabigatran Etexilate Mesylate

    2. 872728-81-9

    3. Pradaxa

    4. Ethyl 3-[[2-[[4-[(z)-n'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic Acid

    5. Dtxsid20236248

    6. Ex-a1966

    7. Mfcd25424070

    8. S5960

    9. Ccg-213236

    10. Cs-w004358

    11. (z)-ethyl 3-(2-(((4-(n'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-n-(pyridin-2-yl)-1h-benzo[d]imidazole-5-carboxamido)propanoate Methanesulfonate

    12. 728p819

    2.3 Create Date
    2006-10-26
    3 Chemical and Physical Properties
    Molecular Weight 723.8 g/mol
    Molecular Formula C35H45N7O8S
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count11
    Rotatable Bond Count17
    Exact Mass723.30503259 g/mol
    Monoisotopic Mass723.30503259 g/mol
    Topological Polar Surface Area217 Ų
    Heavy Atom Count51
    Formal Charge0
    Complexity1100
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NamePradaxa
    PubMed HealthDabigatran (By mouth)
    Drug ClassesAnticoagulant
    Drug LabelThe chemical name for dabigatran etexilate mesylate, a direct thrombin inhibitor, is -Alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-,ethyl ester, methanesulfo...
    Active IngredientDabigatran etexilate mesylate
    Dosage FormCapsule
    RouteOral
    Strengtheq 150mg base; eq 75mg base
    Market StatusPrescription
    CompanyBoehringer Ingelheim

    2 of 2  
    Drug NamePradaxa
    PubMed HealthDabigatran (By mouth)
    Drug ClassesAnticoagulant
    Drug LabelThe chemical name for dabigatran etexilate mesylate, a direct thrombin inhibitor, is -Alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-,ethyl ester, methanesulfo...
    Active IngredientDabigatran etexilate mesylate
    Dosage FormCapsule
    RouteOral
    Strengtheq 150mg base; eq 75mg base
    Market StatusPrescription
    CompanyBoehringer Ingelheim

    4.2 Drug Indication

    Pradaxa 75 mg

    - Primary prevention of venous thromboembolic events in adult patients who have undergone elective total hip replacement surgery or total knee replacement surgery.

    Pradaxa 110 mg

    - Primary prevention of venous thromboembolic events in adult patients who have undergone elective total hip replacement surgery or total knee replacement surgery.

    - Prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF), with one or more risk factors, such as prior stroke or transient ischemic attack (TIA); age 75 years; heart failure (NYHA Class II); diabetes mellitus; hypertension.

    - Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT and PE in adults.

    Pradaxa 150 mg

    - Prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF), with one or more risk factors, such as prior stroke or transient ischemic attack (TIA); age 75 years; heart failure (NYHA Class II); diabetes mellitus; hypertension.

    - Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT and PE in adults.

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Antithrombins

    Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins. (See all compounds classified as Antithrombins.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Thrombin Inhibitors [MoA]; Direct Thrombin Inhibitor [EPC]
    5.3 ATC Code

    B01AE07

    API Reference Price

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DOMODEDOVO","customer":"M\/S....","customerCountry":"RUSSIA","quantity":"181.65","actualQuantity":"181.65","unit":"KGS","unitRateFc":"34900","totalValueFC":"74339.5","currency":"INR","unitRateINR":34387.530580787228,"date":"25-Oct-2024","totalValueINR":"6246494.93","totalValueInUsd":"74339.5","indian_port":"Bangalore Air","hs_no":"29420090","bill_no":"5140454","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pellets","supplierPort":"Bangalore Air","supplierAddress":"20TH K M, HOSUR ROAD,,ELECTRONIC C, BANGALORE,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732991400,"product":"DABIGATRAN ETEXILATE MESYLATE","address":"SYNO.257 258\/1, DNO.11-6\/56,","city":"VILLAGE BALANGAR POST HYDERABAD","supplier":"LEE PHARMA","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"NATIONAL HEALTHCARE PVT ","customerCountry":"NEPAL","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"46000","totalValueFC":"2165.5","currency":"INR","unitRateINR":46000,"date":"01-Dec-2024","totalValueINR":"184000","totalValueInUsd":"2165.5","indian_port":"Raxaul","hs_no":"29333200","bill_no":"6081177","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"Raxaul","supplierAddress":"SYNO.257 258\/1, DNO.11-6\/56,, VILLAGE BALANGAR POST HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734633000,"product":"DABIGATRAN PELLETS TECHNICAL GRADE (BATCH NO-BS24006957\/BF24005995)","address":"20TH K M, HOSUR ROAD,,ELECTRONIC C","city":"BANGALORE,KARNATAKA","supplier":"BIOCON","supplierCountry":"INDIA","foreign_port":"MOSCOW DOMODEDOVO","customer":"M\/S....","customerCountry":"RUSSIA","quantity":"180.00","actualQuantity":"180","unit":"KGS","unitRateFc":"407.7","totalValueFC":"72764.2","currency":"USD","unitRateINR":34348.346666666672,"date":"20-Dec-2024","totalValueINR":"6182702.4","totalValueInUsd":"72764.2","indian_port":"Bangalore Air","hs_no":"29420090","bill_no":"6635928","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pellets","supplierPort":"Bangalore Air","supplierAddress":"20TH K M, HOSUR ROAD,,ELECTRONIC C, BANGALORE,KARNATAKA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"DABIGATRAN ETEXILATE MESYLATE","year":"2021","qtr":"Q1","strtotime":1611513000,"product":"IMPURITIES-DABIGATRAN ETEXILATE MESYLATE PART NO : AFLH005254(QTY10 GRAMS)( DEBIT SR.NO.3)","address":"1-1-151\/1, SAIRAM TOWERS, 4TH FLOORALEXANDER ROAD","city":"SECUNDERABAD, ANDHRA PRADESH","supplier":"VIATRIS","supplierCountry":"INDIA","foreign_port":"PITTSBURGH","customer":"VIATRIS","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"0.01","unit":"KGS","unitRateFc":"1000","totalValueFC":"10.1","currency":"USD","unitRateINR":"73871","date":"25-Jan-2021","totalValueINR":"738.71","totalValueInUsd":"10.1","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"2490855","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"PITTSBURGH","supplierAddress":"","customerAddress":"1-1-151\/1, SAIRAM TOWERS, 4TH FLOORALEXANDER ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1633717800,"product":"PLACEBO OF DABIGATRAN PELLETS 36.144%","address":"PLOT NO 2A & 2B, BIOTECH PARK,,PHA SE II, LALGADI MALAKPET,","city":"HYDERABAD,TELANGANA","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"NA","customer":"CHEMO","customerCountry":"INDIA","quantity":"0.30","actualQuantity":"0.3","unit":"KGS","unitRateFc":"33.3","totalValueFC":"10.1","currency":"USD","unitRateINR":"2523.3","date":"09-Oct-2021","totalValueINR":"757","totalValueInUsd":"10.1","indian_port":"HYDERABAD AIR","hs_no":"29420090","bill_no":"5771638","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pellets","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO 2A & 2B, BIOTECH PARK,,PHA SE II, LALGADI MALAKPET,"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637001000,"product":"DABIGATRAN ETEXILATE MESYLATE","address":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA","city":"MUMBAI,MAHARASHTRA","supplier":"MEDICHEM S.A","supplierCountry":"MALTA","foreign_port":"NA","customer":"ALKEM LABORATORIES","customerCountry":"INDIA","quantity":"82.00","actualQuantity":"82","unit":"KGS","unitRateFc":"2300","totalValueFC":"223115.1","currency":"EUR","unitRateINR":"202630","date":"16-Nov-2021","totalValueINR":"16615660","totalValueInUsd":"223115.1","indian_port":"BOMBAY AIR","hs_no":"29335990","bill_no":"6267308","productDescription":"API","marketType":"REGULATED MARKET","country":"MALTA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1648578600,"product":"DABIGATRAN ETEXILATE MESYLATE","address":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA","city":"MUMBAI,MAHARASHTRA","supplier":"MEDICHEM S.A","supplierCountry":"MALTA","foreign_port":"NA","customer":"ALKEM LABORATORIES","customerCountry":"INDIA","quantity":"45.00","actualQuantity":"45","unit":"KGS","unitRateFc":"2300","totalValueFC":"116034.3","currency":"EUR","unitRateINR":"196535","date":"30-Mar-2022","totalValueINR":"8844075","totalValueInUsd":"116034.3","indian_port":"BOMBAY AIR","hs_no":"29335990","bill_no":"8068488","productDescription":"API","marketType":"REGULATED MARKET","country":"MALTA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1652725800,"product":"DABIGATRAN ETEXILATE MESYLATE","address":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA","city":"MUMBAI,MAHARASHTRA","supplier":"MEDICHEM S.A","supplierCountry":"MALTA","foreign_port":"NA","customer":"ALKEM LABORATORIES","customerCountry":"INDIA","quantity":"75.40","actualQuantity":"75.4","unit":"KGS","unitRateFc":"2300","totalValueFC":"185008","currency":"EUR","unitRateINR":"189635","date":"17-May-2022","totalValueINR":"14298479","totalValueInUsd":"185008","indian_port":"BOMBAY AIR","hs_no":"29335990","bill_no":"8716426","productDescription":"API","marketType":"REGULATED MARKET","country":"MALTA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1673807400,"product":"DABIGATRAN ETEXILATE MESYLATE","address":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA","city":"MUMBAI,MAHARASHTRA","supplier":"MEDICHEM S.A","supplierCountry":"MALTA","foreign_port":"NA","customer":"ALKEM LABORATORIES","customerCountry":"INDIA","quantity":"28.46","actualQuantity":"28.46","unit":"KGS","unitRateFc":"2300","totalValueFC":"71655.2","currency":"EUR","unitRateINR":"205850","date":"16-Jan-2023","totalValueINR":"5858491","totalValueInUsd":"71655.2","indian_port":"BOMBAY AIR","hs_no":"29335990","bill_no":"4206230","productDescription":"API","marketType":"REGULATED MARKET","country":"MALTA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ALKEM HOUSE, DEVASHISH ADJACENT T O,MATULYA CENTRE, SENAPATI BAPAT MA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675017000,"product":"412145,DABIGATRAN ETEXILATE MESYLATE BATCH# TN0175 (PHARMACEUTICAL PRODUCTS)","address":"SITE NO.1,BOMMASANDRA INDL.AREA,IV ,PHASE,JIGANI LINK ROAD ANEKAL TALU","city":"BANGALORE,KARNATAKA","supplier":"APOTEX INC","supplierCountry":"CANADA","foreign_port":"NA","customer":"APOTEX INC","customerCountry":"INDIA","quantity":"18.69","actualQuantity":"18.69","unit":"KGS","unitRateFc":"2177","totalValueFC":"30506.3","currency":"CAD","unitRateINR":"133450.1","date":"30-Jan-2023","totalValueINR":"2494182.37","totalValueInUsd":"30506.3","indian_port":"BANGALORE AIR","hs_no":"29339990","bill_no":"4404124","productDescription":"API","marketType":"REGULATED MARKET","country":"CANADA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SITE NO.1,BOMMASANDRA INDL.AREA,IV ,PHASE,JIGANI LINK ROAD ANEKAL TALU"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1681324200,"product":"DABIGATRAN ETEXILATE MESYLATE( RE-IMPORT FOR REPROCESS & REEXPORT VIDE SB NO.2295061 DT.22.06.2022)","address":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD","city":"HYDERABAD","supplier":"OMAN PHARM PRODUCTS","supplierCountry":"INDIA","foreign_port":"NA","customer":"MSN LABORATORIES","customerCountry":"INDIA","quantity":"149.42","actualQuantity":"149.42303","unit":"KGS","unitRateFc":"600","totalValueFC":"93780.3","currency":"USD","unitRateINR":"51435.5","date":"13-Apr-2023","totalValueINR":"7685651.78","totalValueInUsd":"93780.3","indian_port":"HYDERABAD AIR","hs_no":"29333919","bill_no":"5501463","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1686853800,"product":"P\/NO.: DABIGATRAN ETEXILATE MESYLATE 43% IR PELLETS","address":"SY NO.810, PLOT NO.19 B1 B2 B3,IDA PHASE II, PATANCHERU,","city":"HYDERABAD,TELANGANA","supplier":"JSC NOBEL ALMATINSKAYA FARMAZEVTICHESKAYA","supplierCountry":"INDIA","foreign_port":"NA","customer":"ANWITA DRUGS & CHEMICALS PVT LTD","customerCountry":"INDIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"685","totalValueFC":"17302.9","currency":"USD","unitRateINR":"56888.9","date":"16-Jun-2023","totalValueINR":"1422230.88","totalValueInUsd":"17302.9","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"0","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pellets","supplierPort":"NA","supplierAddress":"","customerAddress":"SY NO.810, PLOT NO.19 B1 B2 B3,IDA PHASE II, PATANCHERU,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1694457000,"product":"DABIGATRAN ETEXILATE MESYLATE (RE-IMP VIDE SB.NO:5135663 DT07.10.2021)","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"CHEMO","supplierCountry":"INDIA","foreign_port":"MADRID","customer":"MSN LABORATORIES","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"1000","totalValueFC":"103054","currency":"USD","unitRateINR":"85543.3","date":"12-Sep-2023","totalValueINR":"8554332.27","totalValueInUsd":"103054","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"7787428","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRID","supplierAddress":"MANUEL POMBO ANGULO,3RD FLOORMADRID-28050 SPAINSDNF ES","customerAddress":"MSN HOUSE, PLOT NO. C-24,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1694457000,"product":"DABIGATRAN ETEXILATE MESYLATE (RE-IMP VIDE SB.NO:5941445 DT12.11.2021)","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"CHEMO","supplierCountry":"INDIA","foreign_port":"MADRID","customer":"MSN LABORATORIES","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"1000","totalValueFC":"103054","currency":"USD","unitRateINR":"85543.3","date":"12-Sep-2023","totalValueINR":"8554332.27","totalValueInUsd":"103054","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"7787428","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRID","supplierAddress":"MANUEL POMBO ANGULO,3RD FLOORMADRID-28050 SPAINSDNF ES","customerAddress":"MSN HOUSE, PLOT NO. C-24,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732127400,"product":"DABIGATRAN ETEXILATE MESYLATE IH","address":"HETERO CORPORATE, NO. 7-2-A2,","city":"HYDERABAD","supplier":"HETERO DRUGS LTD UNIT IX","supplierCountry":"INDIA","foreign_port":"HIPL SEZ","customer":"HETERO DRUGS","customerCountry":"INDIA","quantity":"430.05","actualQuantity":"430.05","unit":"KGS","unitRateFc":"680","totalValueFC":"295573.4","currency":"USD","unitRateINR":"58000","date":"21-Nov-2024","totalValueINR":"24942900","totalValueInUsd":"295573.4","indian_port":"Vizag-HIPL SEZ","hs_no":"29333990","bill_no":"6796863","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"HIPL SEZ","supplierAddress":"PLOT NO 1 HETERO INFRASTRUCTURE SEZ N.NARASAPURAM (V), NAKKAPALLY SDNF India","customerAddress":"HETERO CORPORATE, NO. 7-2-A2,"}]
    12-Jan-2021
    20-Dec-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    Europe

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    01

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    Registration Country : Sweden

    dabigatranetexilatmesilat

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    Dosage Strength : 150 MG

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    Registration Country : Sweden

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    Registration Country : Italy

    dabigatran

    Brand Name : Pradaxa

    Dosage Form : Dabigatran 150Mg 60 Units Oral Use

    Dosage Strength : 60x1 cps 150 mg

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    Registration Country : Italy

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    Registration Country : Norway

    DABIGATRAN ETEXILATE MESYLATE

    Brand Name : Pradaxa

    Dosage Form : Capsule, hard

    Dosage Strength : 110 mg

    Packaging : Blister, endose

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    DABIGATRAN ETEXILATE MESYLATE

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    Dosage Form : Capsule, hard

    Dosage Strength : 150 mg

    Packaging : Blister, endose

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    Registration Country : Norway

    DABIGATRAN ETEXILATE MESYLATE

    Brand Name : Pradaxa

    Dosage Form : Capsule, hard

    Dosage Strength : 75 mg

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    Dabigatran

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    Dosage Form : Hard Capsule

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    Packaging : 60 UNITS 150 MG - ORAL USE

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    Dabigatranum etexilatum

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    Dabigatran

    Brand Name : DABIGATRAN ETEXYLATED DOC

    Dosage Form : Hard Capsules

    Dosage Strength : 110 mg

    Packaging : 30 UNITS 110 MG - ORAL USE

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    Registration Country : Italy

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    Regulatory Info :

    Registration Country : Italy

    Dabigatran

    Brand Name : DABIGATRAN ETEXYLATED EG STADA

    Dosage Form : Hard Capsules

    Dosage Strength : 150 mg

    Packaging : 60 UNITS 150 MG - ORAL USE

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    Regulatory Info :

    Registration Country : Norway

    Dabigatraneteksilatmesilat

    Brand Name : Dabigatran etexilate Sandoz

    Dosage Form : Kapsel, hard

    Dosage Strength : 150 mg

    Packaging : Boks 60item

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    Registration Country : Norway

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - CAPSULE;ORAL - EQ 110MG BASE

    USFDA APPLICATION NUMBER - 22512

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    DOSAGE - CAPSULE;ORAL - EQ 150MG BASE

    USFDA APPLICATION NUMBER - 22512

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    DOSAGE - CAPSULE;ORAL - EQ 75MG BASE

    USFDA APPLICATION NUMBER - 22512

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    ABOUT THIS PAGE

    Looking for 872728-81-9 / Dabigatran Etexilate Mesylate API manufacturers, exporters & distributors?

    Dabigatran Etexilate Mesylate manufacturers, exporters & distributors 1

    41

    PharmaCompass offers a list of Dabigatran Etexilate Mesylate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Dabigatran Etexilate Mesylate manufacturer or Dabigatran Etexilate Mesylate supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Dabigatran Etexilate Mesylate manufacturer or Dabigatran Etexilate Mesylate supplier.

    PharmaCompass also assists you with knowing the Dabigatran Etexilate Mesylate API Price utilized in the formulation of products. Dabigatran Etexilate Mesylate API Price is not always fixed or binding as the Dabigatran Etexilate Mesylate Price is obtained through a variety of data sources. The Dabigatran Etexilate Mesylate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Dabigatran Etexilate Mesylate

    Synonyms

    872728-81-9, Pradaxa, Ethyl 3-[[2-[[4-[(z)-n'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic acid, Dtxsid20236248, Ex-a1966, Mfcd25424070

    Cas Number

    872728-81-9

    About Dabigatran Etexilate Mesylate

    A THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.

    Dabigatran Etexilate Manufacturers

    A Dabigatran Etexilate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dabigatran Etexilate, including repackagers and relabelers. The FDA regulates Dabigatran Etexilate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dabigatran Etexilate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Dabigatran Etexilate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Dabigatran Etexilate Suppliers

    A Dabigatran Etexilate supplier is an individual or a company that provides Dabigatran Etexilate active pharmaceutical ingredient (API) or Dabigatran Etexilate finished formulations upon request. The Dabigatran Etexilate suppliers may include Dabigatran Etexilate API manufacturers, exporters, distributors and traders.

    click here to find a list of Dabigatran Etexilate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Dabigatran Etexilate USDMF

    A Dabigatran Etexilate DMF (Drug Master File) is a document detailing the whole manufacturing process of Dabigatran Etexilate active pharmaceutical ingredient (API) in detail. Different forms of Dabigatran Etexilate DMFs exist exist since differing nations have different regulations, such as Dabigatran Etexilate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Dabigatran Etexilate DMF submitted to regulatory agencies in the US is known as a USDMF. Dabigatran Etexilate USDMF includes data on Dabigatran Etexilate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Dabigatran Etexilate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Dabigatran Etexilate suppliers with USDMF on PharmaCompass.

    Dabigatran Etexilate KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Dabigatran Etexilate Drug Master File in Korea (Dabigatran Etexilate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Dabigatran Etexilate. The MFDS reviews the Dabigatran Etexilate KDMF as part of the drug registration process and uses the information provided in the Dabigatran Etexilate KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Dabigatran Etexilate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Dabigatran Etexilate API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Dabigatran Etexilate suppliers with KDMF on PharmaCompass.

    Dabigatran Etexilate CEP

    A Dabigatran Etexilate CEP of the European Pharmacopoeia monograph is often referred to as a Dabigatran Etexilate Certificate of Suitability (COS). The purpose of a Dabigatran Etexilate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Dabigatran Etexilate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Dabigatran Etexilate to their clients by showing that a Dabigatran Etexilate CEP has been issued for it. The manufacturer submits a Dabigatran Etexilate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Dabigatran Etexilate CEP holder for the record. Additionally, the data presented in the Dabigatran Etexilate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Dabigatran Etexilate DMF.

    A Dabigatran Etexilate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Dabigatran Etexilate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Dabigatran Etexilate suppliers with CEP (COS) on PharmaCompass.

    Dabigatran Etexilate WC

    A Dabigatran Etexilate written confirmation (Dabigatran Etexilate WC) is an official document issued by a regulatory agency to a Dabigatran Etexilate manufacturer, verifying that the manufacturing facility of a Dabigatran Etexilate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Dabigatran Etexilate APIs or Dabigatran Etexilate finished pharmaceutical products to another nation, regulatory agencies frequently require a Dabigatran Etexilate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Dabigatran Etexilate suppliers with Written Confirmation (WC) on PharmaCompass.

    Dabigatran Etexilate NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Dabigatran Etexilate as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Dabigatran Etexilate API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Dabigatran Etexilate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Dabigatran Etexilate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Dabigatran Etexilate NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Dabigatran Etexilate suppliers with NDC on PharmaCompass.

    Dabigatran Etexilate GMP

    Dabigatran Etexilate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Dabigatran Etexilate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dabigatran Etexilate GMP manufacturer or Dabigatran Etexilate GMP API supplier for your needs.

    Dabigatran Etexilate CoA

    A Dabigatran Etexilate CoA (Certificate of Analysis) is a formal document that attests to Dabigatran Etexilate's compliance with Dabigatran Etexilate specifications and serves as a tool for batch-level quality control.

    Dabigatran Etexilate CoA mostly includes findings from lab analyses of a specific batch. For each Dabigatran Etexilate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Dabigatran Etexilate may be tested according to a variety of international standards, such as European Pharmacopoeia (Dabigatran Etexilate EP), Dabigatran Etexilate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dabigatran Etexilate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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