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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

19 API Suppliers, 10 USDMF, 6 JDMF, 1 EU WC, 7 Listed Suppliers, $ API Reference Price

19 API Suppliers
10 USDMF
6 JDMF
1 EU WC
7 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

131 FDF Dossiers, 15 FDA Orange Book, 77 Europe, 21 Canada, 11 South Africa, 7 Listed Dossiers

131 FDF Dossiers
15 FDA Orange Book
77 Europe
21 Canada
11 South Africa
7 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

INJECTABLE;SUBCUTANEOUS - 10,000IU/ML (10,000IU/ML), INJECTABLE;SUBCUTANEOUS - 10,000IU/4ML (2,500IU/ML), INJECTABLE;SUBCUTANEOUS - 12,500IU/0.5ML (25,000IU/ML), INJECTABLE;SUBCUTANEOUS - 15,000IU/0.6ML (25,000IU/ML), INJECTABLE;SUBCUTANEOUS - 18,000IU/0.72ML (25,000IU/ML), INJECTABLE;SUBCUTANEOUS - 2,500IU/0.2ML (12,500IU/ML), INJECTABLE;SUBCUTANEOUS - 5,000IU/0.2ML (25,000IU/ML), INJECTABLE;SUBCUTANEOUS - 7,500IU/0.3ML (25,000IU/ML), INJECTABLE;SUBCUTANEOUS - 95,000IU/3.8ML (25,000IU/ML)

drugProductComposition
INJECTABLE;SUBCUTANEOUS - 10,000IU/ML (10,000IU/ML)
INJECTABLE;SUBCUTANEOUS - 10,000IU/4ML (2,500IU/ML)
INJECTABLE;SUBCUTANEOUS - 12,500IU/0.5ML (25,000IU/ML)
INJECTABLE;SUBCUTANEOUS - 15,000IU/0.6ML (25,000IU/ML)
INJECTABLE;SUBCUTANEOUS - 18,000IU/0.72ML (25,000IU/ML)
INJECTABLE;SUBCUTANEOUS - 2,500IU/0.2ML (12,500IU/ML)
INJECTABLE;SUBCUTANEOUS - 5,000IU/0.2ML (25,000IU/ML)
INJECTABLE;SUBCUTANEOUS - 7,500IU/0.3ML (25,000IU/ML)
INJECTABLE;SUBCUTANEOUS - 95,000IU/3.8ML (25,000IU/ML)

RELATED EXCIPIENT COMPANIES

1 Nanjing Well Pharmaceutical, 3 Actylis, 1 Finar

relatedExcipients
1 Nanjing Well Pharmaceutical
3 Actylis
1 Finar

EXCIPIENTS BY APPLICATIONS

3 Parenteral, 2 Topical, 1 Solubilizers

excipientsByApplications
3 Parenteral
2 Topical
1 Solubilizers

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 3 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
3 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 46 Finished Drug Prices, 5 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
46 Finished Drug Prices
5 Annual Reports

MARKET PLACE

16 APIs, 43 FDF Dossiers

marketPlace
16 APIs
43 FDF Dossiers

REF. STANDARDS & IMPURITIES

2 EDQM , 1 USP , 1 Others

otherSolutions
2 EDQM
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 29,094

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

131

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

1,939,380

Annual Reports (USD Million)

1,317

Finished Drug Prices

5 RELATED EXCIPIENT COMPANIES

6EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:

Molecular Formula

C₁₂H₁₇NO₂₀S₃-₄

Molecular Weight

591.5 g/mol

InChI Key

OHJKXVLJWUPWQG-IUYNYSEKSA-J

1 2D Structure

Dalteparin sodium

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4S,6R)-6-[(2R,4R)-4,6-dihydroxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfonatooxyoxane-2-carboxylate

2.1.2 InChI

InChI=1S/C12H21NO20S3/c14-4-3(13-34(20,21)22)11(19)30-2(1-29-35(23,24)25)7(4)31-12-9(33-36(26,27)28)6(16)5(15)8(32-12)10(17)18/h2-9,11-16,19H,1H2,(H,17,18)(H,20,21,22)(H,23,24,25)(H,26,27,28)/p-4/t2-,3?,4-,5?,6+,7?,8?,9?,11?,12-/m1/s1

2.1.3 InChI Key

OHJKXVLJWUPWQG-IUYNYSEKSA-J

2.1.4 Canonical SMILES

C(C1C(C(C(C(O1)O)NS(=O)(=O)[O-])O)OC2C(C(C(C(O2)C(=O)[O-])O)O)OS(=O)(=O)[O-])OS(=O)(=O)[O-]

2.1.5 Isomeric SMILES

C([C@@H]1C([C@@H](C(C(O1)O)NS(=O)(=O)[O-])O)O[C@H]2C([C@H](C(C(O2)C(=O)[O-])O)O)OS(=O)(=O)[O-])OS(=O)(=O)[O-]

2.2 Create Date

2009-05-14

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₇NO₂₀S₃-₄
Molecular Weight	591.5 g/mol
XLogP3	-5.6
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	21
Rotatable Bond Count	6
Exact Mass	590.95060545 g/mol
Monoisotopic Mass	590.95060545 g/mol
Topological Polar Surface Area	376 Å²
Heavy Atom Count	36
Formal Charge	-4
Complexity	1040
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	6
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Heparin sodium in plastic container
Active Ingredient	Heparin sodium
Dosage Form	Injectable
Route	Injection
Strength	10,000 units/ml; 5,000 units/ml; 20,000 units/ml; 1,000 units/ml
Market Status	Prescription
Company	Fresenius Kabi Usa

2 of 4
Drug Name	Heparin sodium preservative free
Active Ingredient	Heparin sodium
Dosage Form	Injectable
Route	Injection
Strength	10,000 units/ml; 1,000 units/ml
Market Status	Prescription
Company	Hospira; Shenzhen Techdow; Pfizer; Fresenius Kabi Usa; Sagent Pharms

3 of 4
Drug Name	Heparin sodium in plastic container
Active Ingredient	Heparin sodium
Dosage Form	Injectable
Route	Injection
Strength	10,000 units/ml; 5,000 units/ml; 20,000 units/ml; 1,000 units/ml
Market Status	Prescription
Company	Fresenius Kabi Usa

4 of 4
Drug Name	Heparin sodium preservative free
Active Ingredient	Heparin sodium
Dosage Form	Injectable
Route	Injection
Strength	10,000 units/ml; 1,000 units/ml
Market Status	Prescription
Company	Hospira; Shenzhen Techdow; Pfizer; Fresenius Kabi Usa; Sagent Pharms

API SUPPLIERS

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USDMF

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JDMF

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EU WC

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Listed Suppliers

01

Biological E

India

Cosmoprof India

Not Confirmed

02

Dongying Tiandong Pharmaceutical Co...

China

Cosmoprof India

Not Confirmed

Dongying Tiandong Pharmaceutical Co...

China

Cosmoprof India

Not Confirmed

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China

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Digital Content

Dalteparin sodium

About the Company : Dongying Tiandong Pharmaceutical Co.,ltd founded in 1992, subordinated to Shandong Haike Chemical Group, is located in Dongying city, the center area of Yellow River Delta High-eff...

Dongying Tiandong Pharmaceutical Co.,ltd founded in 1992, subordinated to Shandong Haike Chemical Group, is located in Dongying city, the center area of Yellow River Delta High-efficiency Ecological Economic Zone and Shandong Peninsula Blue Economic Zone, specially engaging in development, production and sales of polysaccharide products. The company is entitled as High and New Tech Enterprise in ShandongProvince. The company focuses on low-molecular weight heparins, heparin sodium and heparin calcium and so on, as the biggest low-molecular weight heparin API manufacturer in China. The injection workshop has been built with annual capacity of 21 million units of aqueous solution injections, which makes the company to have the complete industry chain from API to injection product and updates the heparin industry chain. Tiandong company is the only one to pass EDQM inspection, granted COS for enoxapairn sodium in China. Moreover, its enoxaparin sodium has been granted with Brazil GMP certificate, Swedish GMP certificate and French GMP certificate successively, and completed the registrations in many other countries and regions, and has been exported to more than forty countries in the world. The company keeps long-term close partnership with School of Pharmaceutical Sciences, ShandongUniversity, which strengthens our innovative ability of R & D. The company has applied 15 invention patents or utility model patents associated with heparin products. In 2009, the company has undertaken the national Major Creation of new drugs project on Quality Standards Study and Establishment of Five Low Molecular Weight Heparins. Over 20 years, the company has always made efforts to provide better pharmaceutical products and services for people, and established impeccable production service management system and quality management system by years of practices and innovation to assure product quality and the interests of clients.

Portfolio PDF

Product Web Link

Virtual Booth

Digital Content

Website

Corporate PDF

03

GLAND PHARMA LIMITED

India

Cosmoprof India

Not Confirmed

04

Hanways Chempharm

China

Cosmoprof India

Not Confirmed

05

HEBEI CHANGSHAN BIOCHEMICAL PHARMAC...

China

Cosmoprof India

Not Confirmed

06

Prajna Generics

India

Cosmoprof India

Not Confirmed

07

Tecoland Corporation

U.S.A

Cosmoprof India

Not Confirmed

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FDF Dossiers

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FDA Orange Book

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Europe

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Canada

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South Africa

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Listed Dossiers

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;SUBCUTANEOUS - 10,000IU/M...DOSAGE - INJECTABLE;SUBCUTANEOUS - 10,000IU/ML (10,000IU/ML)