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Chemistry

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Also known as: 1970972-74-7, Danicamtiv [inn], Danicamtiv [usan], Myk-491, Sar440181, 7b2cs922hi
Molecular Formula
C16H20F3N5O4S
Molecular Weight
435.4  g/mol
InChI Key
NREKKBAMVWQRES-MRXNPFEDSA-N
FDA UNII
7B2CS922HI

Danicamtiv
1 2D Structure

Danicamtiv

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[(1R)-1-[3-(difluoromethyl)-1-methylpyrazol-4-yl]sulfonyl-1-fluoroethyl]-N-(1,2-oxazol-3-yl)piperidine-1-carboxamide
2.1.2 InChI
InChI=1S/C16H20F3N5O4S/c1-16(19,29(26,27)11-9-23(2)21-13(11)14(17)18)10-3-6-24(7-4-10)15(25)20-12-5-8-28-22-12/h5,8-10,14H,3-4,6-7H2,1-2H3,(H,20,22,25)/t16-/m1/s1
2.1.3 InChI Key
NREKKBAMVWQRES-MRXNPFEDSA-N
2.1.4 Canonical SMILES
CC(C1CCN(CC1)C(=O)NC2=NOC=C2)(F)S(=O)(=O)C3=CN(N=C3C(F)F)C
2.1.5 Isomeric SMILES
C[C@@](C1CCN(CC1)C(=O)NC2=NOC=C2)(F)S(=O)(=O)C3=CN(N=C3C(F)F)C
2.2 Other Identifiers
2.2.1 UNII
7B2CS922HI
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 1970972-74-7

2. Danicamtiv [inn]

3. Danicamtiv [usan]

4. Myk-491

5. Sar440181

6. 7b2cs922hi

7. Myk491

8. Sar-440181

9. 1-piperidinecarboxamide, 4-((1r)-1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-3-isoxazolyl-

10. 4-[(1r)-1-[3-(difluoromethyl)-1-methylpyrazol-4-yl]sulfonyl-1-fluoroethyl]-n-(1,2-oxazol-3-yl)piperidine-1-carboxamide

11. Danicamtiv (usan/inn)

12. Danicamtiv (myk-491)

13. Unii-7b2cs922hi

14. Chembl4594304

15. Schembl17942536

16. Ex-a5015

17. S9948

18. Who 10942

19. Sar 440181;myk-491

20. Hy-109128

21. Cs-0086762

22. D11824

23. (r)-4-(1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-(isoxazol-3-yl)piperidine-1-carboxamide

24. 4-((1r)-1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-(1,2-oxazol-3-yl)piperidine-1-carboxamide

2.4 Create Date
2016-12-08
3 Chemical and Physical Properties
Molecular Weight 435.4 g/mol
Molecular Formula C16H20F3N5O4S
XLogP31.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass435.11880980 g/mol
Monoisotopic Mass435.11880980 g/mol
Topological Polar Surface Area119 Ų
Heavy Atom Count29
Formal Charge0
Complexity701
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Danicamtiv Manufacturers

A Danicamtiv manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Danicamtiv, including repackagers and relabelers. The FDA regulates Danicamtiv manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Danicamtiv API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Danicamtiv Suppliers

A Danicamtiv supplier is an individual or a company that provides Danicamtiv active pharmaceutical ingredient (API) or Danicamtiv finished formulations upon request. The Danicamtiv suppliers may include Danicamtiv API manufacturers, exporters, distributors and traders.

Danicamtiv GMP

Danicamtiv Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Danicamtiv GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Danicamtiv GMP manufacturer or Danicamtiv GMP API supplier for your needs.

Danicamtiv CoA

A Danicamtiv CoA (Certificate of Analysis) is a formal document that attests to Danicamtiv's compliance with Danicamtiv specifications and serves as a tool for batch-level quality control.

Danicamtiv CoA mostly includes findings from lab analyses of a specific batch. For each Danicamtiv CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Danicamtiv may be tested according to a variety of international standards, such as European Pharmacopoeia (Danicamtiv EP), Danicamtiv JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Danicamtiv USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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