Find Danicopan manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

Health Canada Patents

DIGITAL CONTENT

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Schembl18578260, Bdbm386574, Us10287301, compound 518, (2r,4s)-1-(2-(3- acetyl-5-(2- methylpyrimidin- 5-yl)-1h-indazol- 1-yl)acetyl)-n-(6- bromopyridin-2- yl)-4- fluoropyrrolidine- 2-carboxamide
Molecular Formula
C26H23BrFN7O3
Molecular Weight
580.4  g/mol
InChI Key
PIBARDGJJAGJAJ-GHTZIAJQSA-N

Danicopan
1 2D Structure

Danicopan

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,4S)-1-[2-[3-acetyl-5-(2-methylpyrimidin-5-yl)indazol-1-yl]acetyl]-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide
2.1.2 InChI
InChI=1S/C26H23BrFN7O3/c1-14(36)25-19-8-16(17-10-29-15(2)30-11-17)6-7-20(19)35(33-25)13-24(37)34-12-18(28)9-21(34)26(38)32-23-5-3-4-22(27)31-23/h3-8,10-11,18,21H,9,12-13H2,1-2H3,(H,31,32,38)/t18-,21+/m0/s1
2.1.3 InChI Key
PIBARDGJJAGJAJ-GHTZIAJQSA-N
2.1.4 Canonical SMILES
CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4CC(CC4C(=O)NC5=NC(=CC=C5)Br)F
2.1.5 Isomeric SMILES
CC1=NC=C(C=N1)C2=CC3=C(C=C2)N(N=C3C(=O)C)CC(=O)N4C[C@H](C[C@@H]4C(=O)NC5=NC(=CC=C5)Br)F
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Schembl18578260

2. Bdbm386574

3. Us10287301, Compound 518

4. (2r,4s)-1-(2-(3- Acetyl-5-(2- Methylpyrimidin- 5-yl)-1h-indazol- 1-yl)acetyl)-n-(6- Bromopyridin-2- Yl)-4- Fluoropyrrolidine- 2-carboxamide

2.3 Create Date
2017-04-22
3 Chemical and Physical Properties
Molecular Weight 580.4 g/mol
Molecular Formula C26H23BrFN7O3
XLogP33.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass579.10298 g/mol
Monoisotopic Mass579.10298 g/mol
Topological Polar Surface Area123 Ų
Heavy Atom Count38
Formal Charge0
Complexity891
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

Digital Content read-more

Create Content with PharmaCompass, ask us

DATA COMPILATION #PharmaFlow

read-more
read-more

NEWS #PharmaBuzz

read-more
read-more

Patents & EXCLUSIVITIES

Check the patents & exclusivity for this product

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty