DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

4 API Suppliers, 1 USDMF, 1 NDC API, 1 VMF, 3 Listed Suppliers

4 API Suppliers
1 USDMF
1 NDC API
1 VMF
3 Listed Suppliers

INTERMEDIATES

4 Intermediates Suppliers

4 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

1 FDF Dossiers, 1 Canada

1 FDF Dossiers
1 Canada

RELATED EXCIPIENT COMPANIES

1 Faran Shimi Pharmaceutical, 2 Boai NKY Pharmaceuticals Ltd, 2 Gangwal Healthcare, 1 Actylis, 10 BASF, 1 Gangwal Chemicals, 1 Microlex e.U, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 1 Pluviaendo, 1 Shanghai Welltone Material Technology Co., Ltd

relatedExcipients
1 Faran Shimi Pharmaceutical
2 Boai NKY Pharmaceuticals Ltd
2 Gangwal Healthcare
1 Actylis
10 BASF
1 Gangwal Chemicals
1 Microlex e.U
1 Novo Excipients
1 Pharmatrans-Sanaq
1 Pluviaendo
1 Shanghai Welltone Material Technology Co., Ltd

EXCIPIENTS BY APPLICATIONS

8 Fillers, Diluents & Binders, 8 Solubilizers, 5 Direct Compression, 5 Parenteral, 5 Granulation, 4 Controlled & Modified Release, 2 Co-Processed Excipients, 2 Thickeners and Stabilizers, 1 Coating Systems & Additives, 1 Disintegrants & Superdisintegrants, 1 Topical, 1 Film Formers & Plasticizers

excipientsByApplications
8 Fillers, Diluents & Binders
8 Solubilizers
5 Direct Compression
5 Parenteral
5 Granulation
4 Controlled & Modified Release
2 Co-Processed Excipients
2 Thickeners and Stabilizers
1 Coating Systems & Additives
1 Disintegrants & Superdisintegrants
1 Topical
1 Film Formers & Plasticizers

MARKET PLACE

4 APIs

marketPlace
4 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

4INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

22 RELATED EXCIPIENT COMPANIES

43EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 119478-55-6, Danofloxacin mesilate, Danofloxacin methanesulfonate, Advocid, Danofloxacin (mesylate), Danofloxacin mesylate [usan]

Molecular Formula

C₂₀H₂₄FN₃O₆S

Molecular Weight

453.5 g/mol

InChI Key

APFDJSVKQNSTKF-FXMYHANSSA-N

FDA UNII

94F3SX3LEM

1 2D Structure

Danofloxacin Mesylate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid

2.1.2 InChI

InChI=1S/C19H20FN3O3.CH4O3S/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10;1-5(2,3)4/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26);1H3,(H,2,3,4)/t11-,12-;/m0./s1

2.1.3 InChI Key

APFDJSVKQNSTKF-FXMYHANSSA-N

2.1.4 Canonical SMILES

CN1CC2CC1CN2C3=C(C=C4C(=C3)N(C=C(C4=O)C(=O)O)C5CC5)F.CS(=O)(=O)O

2.1.5 Isomeric SMILES

CN1C[C@@H]2C[C@H]1CN2C3=C(C=C4C(=C3)N(C=C(C4=O)C(=O)O)C5CC5)F.CS(=O)(=O)O

2.2 Other Identifiers

2.2.1 UNII

94F3SX3LEM

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Advocid

2. Advocin

3. Danofloxacin

2.3.2 Depositor-Supplied Synonyms

1. 119478-55-6

2. Danofloxacin Mesilate

3. Danofloxacin Methanesulfonate

4. Advocid

5. Danofloxacin (mesylate)

6. Danofloxacin Mesylate [usan]

7. Advocin

8. Cp-76136-27

9. 94f3sx3lem

10. 1-cyclopropyl-6-fluoro-1,4-dihydro-7-((1s,4s)-5-methyl-2,5-diazabicyclo(2.2.1)hept-2-yl)-4-oxo-3-quinolinecarboxylic Acid, Monomethanesulfonate

11. Cp-76,136-27

12. 119478-55-6 (mesylate)

13. Danofloxacin Mesylate (usan)

14. Danofloxacin Mesylate 100 Microg/ml In Acetonitrile

15. 1-cyclopropyl-6-fluoro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxoquinoline-3-carboxylic Acid;methanesulfonic Acid

16. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(5-methyl-2,5-diazabicyclo(2.2.1)hept-2-yl)-4-oxo-, (1s)-, Monomethanesulfonate

17. Danofloxacin Mesilate Hydrate [jan]

18. Unii-94f3sx3lem

19. Advocid (tn)

20. Cp 76,136-27

21. Danofloxacin Mesilate Hydrate

22. Schembl418388

23. Danofloxacin Monomethanesulfonate

24. Chembl2106153

25. Dtxsid30922988

26. Chebi:181474

27. 1-cyclopropyl-6-fluoro-7-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Compound With Methanesulfonic Acid (1:1)

28. Hy-b0501

29. Mfcd00673687

30. S3058

31. Danofloxacin Mesilate [mart.]

32. Akos015895387

33. 2,4-dimethylpyrrole-3-carboxylicacid?

34. Ccg-269267

35. 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-3-quinolinecarboxylic Acid Mesylate

36. As-75249

37. Danofloxacin Methanesulfonate [mi]

38. Danofloxacin Mesylate 100 Microg/ml In Water

39. C71643

40. D-0245

41. D03646

42. Danofloxacin Mesylate 100 Microg/ml In Methanol

43. 478d556

44. Q27271680

45. Danofloxacin Mesylate, Antibiotic For Culture Media Use Only

46. 1-cyclopropyl-6-fluoro-7-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Methanesulfonic Acid Salt

47. 1-cyclopropyl-6-fluoro-7-(5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid--methanesulfonic Acid (1/1)

48. 1-cyclopropyl-6-fluoro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; Methanesulfonic Acid

49. 1-cyclopropyl-6-luoro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-4-oxoquinoline-3-carboxylic Acid;methanesulonic Acid

50. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-, Methanesulfonate (1:1)

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₄FN₃O₆S
Molecular Weight	453.5 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Exact Mass	453.13698483 g/mol
Monoisotopic Mass	453.13698483 g/mol
Topological Polar Surface Area	127 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	772
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)

API SUPPLIERS