Find Decitabine manufacturers, exporters & distributors on PharmaCompass

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Virtual Booth

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

32 API Suppliers, 20 USDMF, 10 EU WC, 5 KDMF, 13 NDC API, 16 Listed Suppliers, $ API Reference Price

32 API Suppliers
20 USDMF
10 EU WC
5 KDMF
13 NDC API
16 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

28 Drugs in Development

28 Drugs in Development

INTERMEDIATES

5 Intermediates Suppliers

5 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

41 FDF Dossiers, 22 FDA Orange Book, 6 Europe, 2 Canada, 2 South Africa, 9 Listed Dossiers

41 FDF Dossiers
22 FDA Orange Book
6 Europe
2 Canada
2 South Africa
9 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Actylis, 1 Finar

relatedExcipients
1 Actylis
1 Finar

EXCIPIENTS BY APPLICATIONS

1 Parenteral, 1 Topical

excipientsByApplications
1 Parenteral
1 Topical

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 39 NEWS #PharmaBuzz

media
3 DATA COMPILATION #PharmaFlow
39 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 5 Finished Drug Prices, 3 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
5 Finished Drug Prices
3 Annual Reports

MARKET PLACE

1 APIs

marketPlace
1 APIs

PATENTS & EXCLUSIVITIES

8 US Patents, 2 US Exclusivities

patents
8 US Patents
2 US Exclusivities

REF. STANDARDS & IMPURITIES

3 Others

otherSolutions
3 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

845,696

Annual Reports (USD Million)

216

Finished Drug Prices

2EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 5-aza-2'-deoxycytidine, 2353-33-5, Dacogen, 2'-deoxy-5-azacytidine, 5-azadeoxycytidine, Azadc

Molecular Formula

C₈H₁₂N₄O₄

Molecular Weight

228.21 g/mol

InChI Key

XAUDJQYHKZQPEU-KVQBGUIXSA-N

FDA UNII

776B62CQ27

An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

Decitabine is a Nucleoside Metabolic Inhibitor. The mechanism of action of decitabine is as a Nucleic Acid Synthesis Inhibitor.

1 2D Structure

Decitabine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one

2.1.2 InChI

InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1

2.1.3 InChI Key

XAUDJQYHKZQPEU-KVQBGUIXSA-N

2.1.4 Canonical SMILES

C1C(C(OC1N2C=NC(=NC2=O)N)CO)O

2.1.5 Isomeric SMILES

C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O

2.2 Other Identifiers

2.2.1 UNII

776B62CQ27

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2' Deoxy 5 Azacytidine

2. 2'-deoxy-5-azacytidine

3. 5 Aza 2' Deoxycytidine

4. 5 Azadeoxycytidine

5. 5 Deoxyazacytidine

6. 5-aza-2'-deoxycytidine

7. 5-azadc

8. 5-azadeoxycytidine

9. 5-deoxyazacytidine

10. 5azadc

11. Azadc Compound

12. Compound, Azadc

13. Dacogen

14. Decitabine Mesylate

15. Mesylate, Decitabine

16. Nsc 127716

17. Nsc-127716

18. Nsc127716

2.3.2 Depositor-Supplied Synonyms

1. 5-aza-2'-deoxycytidine

2. 2353-33-5

3. Dacogen

4. 2'-deoxy-5-azacytidine

5. 5-azadeoxycytidine

6. Azadc

7. 5-aza-cdr

8. 5-aza-dc

9. Dezocitidine

10. Nsc 127716

11. Dac

12. 5-aza-deoxycytidine

13. Alpha-decitibine

14. 4-amino-1-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1h)-one

15. Nsc-127716

16. 4-amino-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one

17. 5a2dc

18. 5-aza-2-deoxycytidine

19. 4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one

20. 4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-1,3,5-triazin-2(1h)-one

21. Mls001332587

22. Chebi:50131

23. 776b62cq27

24. Smr000857076

25. 4-amino-1-[(2s,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one

26. Dsstox_cid_10432

27. Dsstox_rid_78849

28. Dsstox_gsid_30432

29. 4-amino-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one

30. 5-azadc

31. Nsc127716

32. 2-deoxyazacytidine

33. 4-amino-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2-one

34. Dacogen (tn)

35. Cas-2353-33-5

36. 2-desoxy-5-azacytidine

37. Ncgc_5adoc

38. Decitabine (usan/inn)

39. Decitabine [usan:inn:ban]

40. Ccris 8227

41. Unii-776b62cq27

42. Ncgc00166088-01

43. 22432-95-7

44. Decitabine- Bio-x

45. Deoxy-5-azacytidine

46. Einecs 219-089-4

47. Mfcd00043011

48. Brn 0617982

49. Decitabine, Free Base

50. Jnj 30979754

51. Jnj-30979754

52. Decitabine [mi]

53. Decitabine [inn]

54. Decitabine [usan]

55. 4-amino-1-(2-deoxy-beta-d-ribofuranosyl)-1,3,5-triazin-2(1h)-one

56. Decitabine [vandf]

57. Molmap_000063

58. E-7373

59. Decitabine [mart.]

60. Schembl4006

61. Decitabine [who-dd]

62. Mls001332588

63. Mls006010136

64. Astx-727

65. Cid_451668

66. Gtpl6805

67. Chembl1201129

68. Decitabine [orange Book]

69. Dtxsid7030432

70. Bdbm96274

71. Ex-a961

72. Inqovi Component Decitabine

73. Hms2235o03

74. Hms3413l07

75. Hms3677l07

76. 105597-46-4

77. 4-amino-1-((2s,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1h)-one

78. Act00147

79. Amy33354

80. Bcp02870

81. Hy-a0004

82. 5-aza-2'-deoxycytidine, >=97%

83. Tox21_112311

84. Astx727 Component Decitabine

85. S1200

86. Zinc16929327

87. Decitabine Component Of Inqovi

88. 4-amino-1-(2-deoxy-?-d-erythro-pentofuranosyl)-1,3,5-triazin-2(1h)-one

89. Akos015895047

90. Astx-727 Component Decitabine

91. Inqovi (decitabine + Cedazuridine)

92. Tox21_112311_1

93. Ac-1135

94. Bcp9000593

95. Ccg-208143

96. Cs-0372

97. Db01262

98. 1,3,5-triazin-2(1h)-one, 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-

99. Astx727 (decitabine + Cedazuridine)

100. Decitabine (nsc127716, 5aza-cdr)

101. Decitabine (nsc127716; 5aza-cdr)

102. Ncgc00166088-02

103. Ncgc00166088-05

104. As-17558

105. Ba164359

106. Bcp0726000271

107. Db-029060

108. Sw218076-2

109. D03665

110. Ab00918337-07

111. Ab00918337_08

112. 353a335

113. Sr-01000838879

114. J-700084

115. Q1181878

116. Sr-01000838879-4

117. Decitabine (2 Inverted Exclamation Marka-deoxy-5-azacytidine).cd

118. S-triazin-2(1h)-one, 4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-

119. 1,3, 5-triazin-2(1h)-one, 4-amino-1-(2-deoxy--d-erythro-pentofuranosyl)-

120. 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one

2.4 Create Date

2005-08-01

3 Chemical and Physical Properties

Molecular Formula	C₈H₁₂N₄O₄
Molecular Weight	228.21 g/mol
XLogP3	-1.2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	228.08585488 g/mol
Monoisotopic Mass	228.08585488 g/mol
Topological Polar Surface Area	121 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	356
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Dacogen
PubMed Health	Decitabine (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Dacogen (decitabine) for Injection contains decitabine (5-aza-2-deoxycitidine), an analogue of the natural nucleoside 2-deoxycytidine. Decitabine is a fine, white to almost white powder with the molecular formula of C8H12N4O4 and a mo...
Active Ingredient	Decitabine
Dosage Form	Injectable
Route	Intravenous
Strength	50mg/vial
Market Status	Prescription
Company	Eisai

2 of 4
Drug Name	Decitabine
PubMed Health	Decitabine (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Decitabine for Injection contains decitabine (5-aza-2deoxycitidine), an analogue of the natural nucleoside 2-deoxycytidine. Decitabine is a fine, white to almost white powder with the molecular formula of C8H12N4O4 and a molecular weight of 228...
Active Ingredient	Decitabine
Dosage Form	Injectable; Powder
Route	Intravenous
Strength	50mg/vial
Market Status	Prescription
Company	Dr Reddys Labs; Sandoz; Sun Pharma Global

3 of 4
Drug Name	Dacogen
PubMed Health	Decitabine (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Dacogen (decitabine) for Injection contains decitabine (5-aza-2-deoxycitidine), an analogue of the natural nucleoside 2-deoxycytidine. Decitabine is a fine, white to almost white powder with the molecular formula of C8H12N4O4 and a mo...
Active Ingredient	Decitabine
Dosage Form	Injectable
Route	Intravenous
Strength	50mg/vial
Market Status	Prescription
Company	Eisai

4 of 4
Drug Name	Decitabine
PubMed Health	Decitabine (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Decitabine for Injection contains decitabine (5-aza-2deoxycitidine), an analogue of the natural nucleoside 2-deoxycytidine. Decitabine is a fine, white to almost white powder with the molecular formula of C8H12N4O4 and a molecular weight of 228...
Active Ingredient	Decitabine
Dosage Form	Injectable; Powder
Route	Intravenous
Strength	50mg/vial
Market Status	Prescription
Company	Dr Reddys Labs; Sandoz; Sun Pharma Global

4.2 Drug Indication

Decitabine is indicated for the treatment of patients with myelodysplastic syndromes (MDS) including all French-American-British subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocytic leukemia), as well as for MDS scored as belonging to the intermediate-1, intermediate-2, or high-risk group in the International Prognostic Scoring System.

FDA Label

Treatment of adult patients with newly diagnosed de novo or secondary acute myeloid leukaemia (AML), according to the World Health Organization (WHO) classification, who are not candidates for standard induction chemotherapy.

5 Pharmacology and Biochemistry

5.1 Pharmacology

Decitabine is a prodrug analogue of the natural nucleotide 2-deoxycytidine, which, upon being phosphorylated intracellularly, is incorporated into DNA and exerts numerous effects on gene expression. The use of decitabine is associated with neutropenia and thrombocytopenia. In addition, decitabine can cause fetal harm in pregnant women; effective contraception and avoidance of pregnancy are recommended during treatment with decitabine.

5.2 MeSH Pharmacological Classification

Enzyme Inhibitors

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

Antimetabolites, Antineoplastic

Antimetabolites that are useful in cancer chemotherapy. (See all compounds classified as Antimetabolites, Antineoplastic.)

5.3 FDA Pharmacological Classification

5.3.1 Active Moiety

DECITABINE

5.3.2 FDA UNII

776B62CQ27

5.3.3 Pharmacological Classes

Nucleoside Metabolic Inhibitor [EPC]; Nucleic Acid Synthesis Inhibitors [MoA]

5.4 ATC Code

L01BC08

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

L - Antineoplastic and immunomodulating agents

L01 - Antineoplastic agents

L01B - Antimetabolites

L01BC - Pyrimidine analogues

L01BC08 - Decitabine

5.5 Absorption, Distribution and Excretion

Absorption

Decitabine administered intravenously at 15 mg/m² for three hours every eight hours over three days resulted in a C_max of 73.8 ng/mL (66% coefficient of variation, CV), an AUC_0- of 163 ng\*h/mL (62% CV), and a cumulative AUC of 1332 ng\*h/mL (95% CI of 1010-1730). Similarly, decitabine at 20 mg/m² for one hour once daily over five days resulted in a C_max of 147 ng/mL (49% CV), an AUC_0- of 115 ng\*h/mL (43% CV), and a cumulative AUC of 570 ng\*h/mL (95% CI of 470-700).

Route of Elimination

Less than 1% of administered decitabine is excreted in the urine.

Volume of Distribution

Decitabine as an apparent volume of distribution of 4.59 1.42 L/kg.

Clearance

Decitabine has a clearance of 125 L/hr/m² (53% CV) when administered intravenously at 15 mg/m² for three hours every eight hours over three days, and a clearance of 210 L/hr/m² (47% CV) at 20 mg/m² for one hour once daily over five days.

5.6 Metabolism/Metabolites

Decitabine is phosphorylated inside cells by the sequential action of deoxycytidine kinase, nucleotide monophosphate kinase, and nucleotide diphosphate kinase, prior to being incorporated into newly synthesized DNA by DNA polymerase. Decitabine not incorporated into cellular DNA undergoes deamination by cytidine deaminase followed by additional degradation prior to excretion.

5.7 Biological Half-Life

Decitabine has a half-life of 0.62 hours (49% CV) when administered intravenously at 15 mg/m² for three hours every eight hours over three days, and a half-life of 0.54 hours (43% CV) at 20 mg/m² for one hour once daily over five days.

5.8 Mechanism of Action

Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that manifest in peripheral cytopenias and may eventually progress to secondary acute myeloid leukemia (sAML). Included in the over 45 genes commonly mutated in MDS patients are those involved in DNA methylation and histone modification, and it is well-established that alteration of the epigenetic landscape is a feature of myeloid leukemias. Decitabine is considered a prodrug, as it requires transport into cells and subsequent phosphorylation by distinct kinases to generate the active molecule 5-aza-2'-deoxycytidine-triphosphate, which is incorporated by DNA polymerase during DNA replication. Once incorporated into DNA, decitabine is recognized as a substrate by DNA methyltransferase enzymes (DNMTs), specifically DNMT1, but due to the presence of an N5 rather than C5 atom, traps the DNMT through the irreversible formation of a covalent bond. At low concentrations, this mode of action depletes DNMTs and results in global DNA hypomethylation while at high concentrations, it additionally results in double-strand breaks and cell death. The general hypothesis regarding decitabine's therapeutic efficacy is that the global hypomethylation it induces results in the expression of previously silent tumour suppressor genes. However, there are other putative mechanisms also related to this change in DNA methylation, including indirect alteration of transcription through effects on transcription factors, indirectly altering histone modifications and chromatin structure, and activating pathways involved in DNA damage response. The overall effect of decitabine is a decrease in neoplastic cell proliferation and an increase in the expression of tumour suppressor genes.

API SUPPLIERS

01

Farmhispania

Spain

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Farmhispania Group, a leading European CDMO in HPAPI Technologies & High Potency Fermentation.

Contact Supplier

Spain

Virtual Booth

Digital Content

USDMF

Click Us!

CEP/COS JDMF EU-WC NDC

KDMF VMF EU

AUDIT

Corporate PDF

02

Biophore India Pharmaceuticals Pvt...

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

03

LGM Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

LGM Pharma accelerates & optimizes the new product pathway from early development through commercialization.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Veranova

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Veranova: A CDMO that manages complexity with confidence.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC NDC

KDMF VMF Others AUDIT

05

Dr. Reddy's Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF

CEP/COS JDMF EU-WC

NDC

KDMF

VMF Others AUDIT

06

Dr. Reddy's Laboratories

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC

NDC

KDMF

VMF Others AUDIT

10

Wuhan Calmland Pharmaceuticals

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Only 10 entries up to this point, click to access all

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

KDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Export","activeIngredients":"DECITABINE","year":"2021","qtr":"Q1","strtotime":1614191400,"product":"DECITABINE WS (QTY: 700 MG)","address":"43-11-56, SUBBALAKSHMI NAGARRAILWAY NEW COLONY","city":"VISAKHAPATNAM, A.P.","supplier":"SIONC PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES BA","customer":"ATTN FABIAN CROCIANL\/CAROLINA ","customerCountry":"ARGENTINA","quantity":"0.00","actualQuantity":"0.7","unit":"GMS","unitRateFc":"75","totalValueFC":"51.9","currency":"USD","unitRateINR":5400.0142857142864,"date":"25-Feb-2021","totalValueINR":"3780.01","totalValueInUsd":"51.9","indian_port":"HYDERABAD AIR","hs_no":"29332990","bill_no":"8917391","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"43-11-56, SUBBALAKSHMI NAGARRAILWAY NEW COLONY, VISAKHAPATNAM, A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DECITABINE","year":"2021","qtr":"Q1","strtotime":1615141800,"product":"DECITABINE (ALPHAISOMER). BATCH NO:DE200 412 MFG.DATE.APR\/2020.RETEST PERIOD APR\/ 2022","address":"112,, MARINE CHAMBERS,11, NEW MARINE LINES,","city":"MUMBAI. MAHARASHTRA","supplier":"ALCON BIOSCIENCES","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"LABORATORIO LKM S.A.","customerCountry":"ARGENTINA","quantity":"0.11","actualQuantity":"110.02","unit":"GMS","unitRateFc":"228.9","totalValueFC":"24924.5","currency":"USD","unitRateINR":16492.790038174877,"date":"08-Mar-2021","totalValueINR":"1814536.76","totalValueInUsd":"24924.5","indian_port":"BOMBAY AIR","hs_no":"29349990","bill_no":"9190666","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"112,, MARINE CHAMBERS,11, NEW MARINE LINES,, MUMBAI. MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1648405800,"product":"DECITABINE","address":"12 6 214 A1, YERMARUS CAMP CROSS,H YDERABAD ROAD","city":"RAICHUR,KARNATAKA","supplier":"SHILPA MEDICARE","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"SAMYANG HOLDINGS CORPORATION","customerCountry":"KOREA, REPUBLIC OF","quantity":"0.50","actualQuantity":"0.502","unit":"KGS","unitRateFc":"150000","totalValueFC":"74141.1","currency":"USD","unitRateINR":11256972.111553784,"date":"28-Mar-2022","totalValueINR":"5651000","totalValueInUsd":"74141.1","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"9264622","productDescription":"API","marketType":"REGULATED MARKET","country":"KOREA,REPUBLIC OF","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"12 6 214 A1, YERMARUS CAMP CROSS,H YDERABAD ROAD, RAICHUR,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1688063400,"product":"BULK DRUG(DECITABINE)","address":"","city":"","supplier":"SHILPA PHARMA LIFESCIENCES LIMITED","supplierCountry":"INDIA","foreign_port":"PAAMIUT","customer":"UNITED STATES PHARMACOPEIAL","customerCountry":"UNITED STATES","quantity":"0.39","actualQuantity":"390","unit":"GMS","unitRateFc":"195","totalValueFC":"75271","currency":"USD","unitRateINR":15864.103500000001,"date":"30-Jun-2023","totalValueINR":"6187000.365","totalValueInUsd":"75271","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700073000,"product":"DECITABINE DBN3 (NB)","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"BASLE","customer":"AIRPHARM PRATTELN(BONEDED WAREHOUSE","customerCountry":"SWITZERLAND","quantity":"1.04","actualQuantity":"1.036","unit":"KGS","unitRateFc":"79200","totalValueFC":"80892.6","currency":"USD","unitRateINR":6501930.5019305013,"date":"16-Nov-2023","totalValueINR":"6736000","totalValueInUsd":"80892.6","indian_port":"Hyderabad Air","hs_no":"29329990","bill_no":"5364119","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710786600,"product":"DECITABINE","address":"112,, MARINE CHAMBERS,","city":"MUMBAI. MAHARASHTRA","supplier":"ALCON BIOSCIENCES","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"TO ORDER","customerCountry":"ARGENTINA","quantity":"0.05","actualQuantity":"50","unit":"GMS","unitRateFc":"225","totalValueFC":"10732.8","currency":"USD","unitRateINR":17824.126799999998,"date":"19-Mar-2024","totalValueINR":"891206.34","totalValueInUsd":"10732.8","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"8450866","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"112,, MARINE CHAMBERS,, MUMBAI. MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1711391400,"product":"DECITABINE","address":"12 6 214 A1 SHILPA HOUSE HYDERABAD ROAD","city":"RAICHUR","supplier":"SHILPA PHARMA LIFESCIENCES LIMITED","supplierCountry":"INDIA","foreign_port":"CHENGDU","customer":"KINDOS PHARMACEUTICALS","customerCountry":"CHINA","quantity":"0.70","actualQuantity":"700","unit":"GMS","unitRateFc":"95","totalValueFC":"64679.8","currency":"USD","unitRateINR":7672.4785714285717,"date":"26-Mar-2024","totalValueINR":"5370735","totalValueInUsd":"64679.8","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"8620697","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"12 6 214 A1 SHILPA HOUSE HYDERABAD ROAD, RAICHUR","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1721068200,"product":"PHARMA INGREDIENTS - DECITABINE IN HOUSE","address":"30, AROHI VILLA, S.P. RING ROAD, BOPAL,","city":"AHMEDABAD","supplier":"GREENCROSS EXPORT PRIVATE ","supplierCountry":"INDIA","foreign_port":"MOSCOW DOMODEDOVO","customer":"TO THE ORDER","customerCountry":"RUSSIA","quantity":"0.28","actualQuantity":"0.28","unit":"KGS","unitRateFc":"200000","totalValueFC":"54982.6","currency":"USD","unitRateINR":16414473.214285713,"date":"16-Jul-2024","totalValueINR":"4596052.5","totalValueInUsd":"54982.6","indian_port":"Ahmedabad Air","hs_no":"29329990","bill_no":"2458645","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad Air","supplierAddress":"30, AROHI VILLA, S.P. RING ROAD, BOPAL,, AHMEDABAD","customerAddress":""},{"dataSource":"API Import","activeIngredients":"DECITABINE","year":"2021","qtr":"Q1","strtotime":1616351400,"product":"DECITABINE","address":"210, MY HOME TYCOON, 6-3-1192,KUNDANBAGH, BEGUMPET","city":"HYDERABAD","supplier":"COMBI BLOCKS INC.","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"ARAGEN LIFE SCIENCES","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"1","unit":"GMS","unitRateFc":"120","totalValueFC":"146.4","currency":"USD","unitRateINR":"10661.4","date":"22-Mar-2021","totalValueINR":"10661.42","totalValueInUsd":"146.4","indian_port":"BANGALORE AIR","hs_no":"29339990","bill_no":"3241593","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"","customerAddress":"210, MY HOME TYCOON, 6-3-1192,KUNDANBAGH, BEGUMPET"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q2","strtotime":1623349800,"product":"DECITABINE","address":"SY.NO. 342, PLOT NOS. 118,119 & 120 ALEAP INDL. ESTATE, ROAD NO. 6","city":"PRAGATHI NAGAR, HYDERABAD (AP)","supplier":"HANWEISHI PHARMCHEM","supplierCountry":"HONG KONG","foreign_port":"HONG KONG","customer":"THERDOSE PHARMA","customerCountry":"INDIA","quantity":"0.04","actualQuantity":"40","unit":"GMS","unitRateFc":"62","totalValueFC":"2493.6","currency":"USD","unitRateINR":"4584.9","date":"11-Jun-2021","totalValueINR":"183396","totalValueInUsd":"2493.6","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"4280968","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"","customerAddress":"SY.NO. 342, PLOT NOS. 118,119 & 120 ALEAP INDL. ESTATE, ROAD NO. 6"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1639074600,"product":"(N.C.V) JNJ-30979754-AAA ,R600352 DECITABINE (REF.STD)1,3,5-TRIAZIN-2(1H)-ONE,4-AMINO-1-(2-DEOXY-B-D-ERYTHRO-PENTOFURANO","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JOHNSON & JOHNSON","supplierCountry":"UNITED STATES","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.02","actualQuantity":"20","unit":"GMS","unitRateFc":"286","totalValueFC":"6567.4","currency":"EUR","unitRateINR":"24767.6","date":"10-Dec-2021","totalValueINR":"495352","totalValueInUsd":"6567.4","indian_port":"BOMBAY AIR","hs_no":"29349990","bill_no":"6622249","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1649874600,"product":"DECITABINE RELATED COMPOUND A (QTY:2X25 MG,PRICE: USD 814\/EACH)(FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00005","unit":"KGS","unitRateFc":"32560000","totalValueFC":"1696.5","currency":"USD","unitRateINR":"2559978000","date":"14-Apr-2022","totalValueINR":"127998.9","totalValueInUsd":"1696.5","indian_port":"HYDERABAD AIR","hs_no":"29321990","bill_no":"8271251","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1649874600,"product":"DECITABINE (QTY:1X100 MG,PRICE: USD 505)(FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0001","unit":"KGS","unitRateFc":"5050000","totalValueFC":"526.2","currency":"USD","unitRateINR":"397048200","date":"14-Apr-2022","totalValueINR":"39704.82","totalValueInUsd":"526.2","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"8271251","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1651689000,"product":"DECITABINE RELATED COMPOUNDS B AND C MIXTURE (QTY:1X25 MG,PRICE: USD 830)(FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.000025","unit":"KGS","unitRateFc":"33200000","totalValueFC":"844.5","currency":"USD","unitRateINR":"2610636400","date":"05-May-2022","totalValueINR":"65265.91","totalValueInUsd":"844.5","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"8552789","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655490600,"product":"DECITABINE STANDARD - BATCH#71394AA007 -RS (QTY 1500 MG)","address":"564\/A\/22, ROAD NO. 92,JUBILEE HILL S,","city":"HYDERABAD,TELANGANA","supplier":"SCINOPHARM TAIWAN, LTD","supplierCountry":"TAIWAN","foreign_port":"NA","customer":"VIATRIS","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0015","unit":"KGS","unitRateFc":"1800000","totalValueFC":"3840.1","currency":"USD","unitRateINR":"199722160","date":"18-Jun-2022","totalValueINR":"299583.24","totalValueInUsd":"3840.1","indian_port":"BANGALORE AIR","hs_no":"29349990","bill_no":"9165338","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"564\/A\/22, ROAD NO. 92,JUBILEE HILL S,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1669919400,"product":"(N.C.V) JNJ-30979754-AAA DECITABINE POWDER (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"CILAG AG","supplierCountry":"SWITZERLAND","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.13","actualQuantity":"130","unit":"GMS","unitRateFc":"230.8","totalValueFC":"31938.3","currency":"CHF","unitRateINR":"20245.5","date":"02-Dec-2022","totalValueINR":"2631916.21","totalValueInUsd":"31938.3","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3567826","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707157800,"product":"DECITABINE (THIRD COUNTRY EXPORT UNDERPARA 2.46 OF EXIM POLICY 2015-20) (40 GRAMS)","address":"112,, MARINE CHAMBERS,","city":"MUMBAI. MAHARASHTRA","supplier":"SHANGHAI WILPOWER INDUSTRIAL ","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"ALCON BIOSCIENCES","customerCountry":"INDIA","quantity":"0.04","actualQuantity":"40","unit":"GMS","unitRateFc":"70","totalValueFC":"2832.9","currency":"USD","unitRateINR":"5876.5","date":"06-Feb-2024","totalValueINR":"235060","totalValueInUsd":"2832.9","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"2013798","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"1958 ZHONG SHAN NORTH ROAD,SHANGHAI200063 CHINASDNF CHINA","customerAddress":"112,, MARINE CHAMBERS,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719340200,"product":"(N.C.V) JNJ-42756493-AAA DECITABINE API (POWDER) (FOR TESTING PURPOSE ONLY)","address":"30 FORJETT STREET","city":"MUMBAI, MAHARASHTRA.","supplier":"CILAG AG","supplierCountry":"SWITZERLAND","foreign_port":"ZURICH","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.13","actualQuantity":"131","unit":"GMS","unitRateFc":"230.8","totalValueFC":"34849.5","currency":"CHF","unitRateINR":"22207.7","date":"26-Jun-2024","totalValueINR":"2909213.59","totalValueInUsd":"34849.5","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"4198326","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ZURICH","supplierAddress":"HOCHSTRASSE 201 CH-8200 SCHAFFHAUSEN, SwitzerlandSDNF Switzerland","customerAddress":"30 FORJETT STREET"}]