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Also known as: 138-14-7, Desferal, Desferrioxamine b mesylate, Deferoxamine mesilate, Desferrioxamine mesylate, Deferoxamine methanesulfonate
Molecular Formula
C26H52N6O11S
Molecular Weight
656.8  g/mol
InChI Key
IDDIJAWJANBQLJ-UHFFFAOYSA-N
FDA UNII
V9TKO7EO6K

Deferoxamine Mesylate
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
1 2D Structure

Deferoxamine Mesylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide;methanesulfonic acid
2.1.2 InChI
InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
2.1.3 InChI Key
IDDIJAWJANBQLJ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
V9TKO7EO6K
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Deferoxamine

2. Deferoxamine B

3. Deferoxamine Mesilate

4. Deferoxamine Methanesulfonate

5. Deferoximine

6. Deferrioxamine B

7. Desferal

8. Desferioximine

9. Desferrioxamine

10. Desferrioxamine B

11. Desferrioxamine B Mesylate

12. Desferroxamine

13. Mesilate, Deferoxamine

14. Mesylate, Deferoxamine

15. Mesylate, Desferrioxamine B

16. Methanesulfonate, Deferoxamine

2.3.2 Depositor-Supplied Synonyms

1. 138-14-7

2. Desferal

3. Desferrioxamine B Mesylate

4. Deferoxamine Mesilate

5. Desferrioxamine Mesylate

6. Deferoxamine Methanesulfonate

7. Deferoxamine B Mesylate

8. Deferoxamine (mesylate)

9. Desferal Mesylate

10. Desferrioxamine Mesilate

11. V9tko7eo6k

12. Nsc-756718

13. Mls000028713

14. Desferrioxamine B Mesylate;dfom

15. Ba-33112

16. N-(5-(3-((5-aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(n-hydroxyacetamido)pentyl)carbamoyl)propionohydroxamic Acid Monomethanesulfonate (salt)

17. Ncgc00017021-01

18. Cas-138-14-7

19. Deferoxaminemesylate

20. Desferal (tn)

21. Deferoxamine-d8 Mesylate

22. Deferoxamine Mesylate Salt

23. Dsstox_cid_17649

24. Dsstox_rid_79351

25. Dsstox_gsid_37649

26. N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-n'-(5-aminopentyl)-n'-hydroxybutanediamide;methanesulfonic Acid

27. Desferal Methanesulfonate

28. Chebi:31460

29. Deferoxamine Mesylate [usan]

30. Nsc644468

31. Desferioxamine Mesylate

32. Sr-01000695424

33. Smr000058548

34. Einecs 205-314-3

35. Unii-v9tko7eo6k

36. Ba 33122

37. 138d147

38. Ccris 8311

39. Deferoxamine Mesylate [usan:usp]

40. Deferoxamini Mesilas

41. Prestwick_988

42. Mfcd00058605

43. Chembl1234

44. Deferoxamine Mesylate (usp)

45. Schembl119982

46. Spectrum1500224

47. Deferoxamine Mesilate (jp17)

48. Dtxsid6037649

49. Hms500e04

50. Hms1570a12

51. Hms1920c16

52. Hms2091k08

53. Hms2097a12

54. Hms2234h23

55. Hms3714a12

56. Pharmakon1600-01500224

57. Deferoxamine Mesilate [jan]

58. Bcp31290

59. Ex-a4085

60. Hy-b0988

61. Tox21_110741

62. Ccg-39770

63. Deferoxamine Mesylate [vandf]

64. Nsc756718

65. S5742

66. Akos026750165

67. Deferoxamine Mesilate [who-dd]

68. Deferoxamine Mesilate [who-ip]

69. Deferoxamine Mesylate [usp-rs]

70. Tox21_110741_1

71. Cs-4479

72. Nsc 756718

73. Nsc-644468

74. Desferrioxamine Mesilate [mart.]

75. Desferrioxamine Mesylate [who-ip]

76. Ncgc00017021-02

77. Ncgc00017021-03

78. Ncgc00094640-01

79. Ncgc00094640-02

80. Ncgc00178802-06

81. Ac-36517

82. Butanediamide, N'-(5-((4-((5-(acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-n-(5-aminopentyl)-n-hydroxy-, Monomethanesulfonate

83. Deferoxamine Mesylate - Cas 138-14-7

84. Deferoxamine Methanesulfonate [mi]

85. Propionohydroxamic Acid, N-(5-(3-((5-aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(n-hydroxyacetamido)pentyl)carbamoyl)-, Monomethanesulfonate (salt)

86. Deferoxamine Mesylate [orange Book]

87. Db-042415

88. Deferoxamine Mesilate [ep Monograph]

89. Deferoxamini Mesilas [who-ip Latin]

90. Deferoxamine Mesylate [usp Monograph]

91. Ft-0603121

92. D01186

93. A807339

94. Sr-01000695424-2

95. Sr-01000695424-3

96. Sr-01000695424-4

97. Deferoxamine Mesylate Salt, Powder, >=92.5% (tlc)

98. Q27114315

99. Desferrioxamine B Mesylate; Dfom;desferrioxamine Mesylate

100. Deferoxamine Mesylate Salt, European Pharmacopoeia (ep) Reference Standard

101. Deferoxamine Mesylate, United States Pharmacopeia (usp) Reference Standard

102. Deferoxamine For System Suitability, European Pharmacopoeia (ep) Reference Standard

103. Butanediamide, N'(-(((((acetylhydroxyamino)pentyl)mino)1,4-dioxobutyl)ydroxyamino)entyl)n-(5-aminopentyl)-n-hydroxy-, Monomethanesulfonate

104. Butanediamide, N'(-(((((acetylhydroxyamino)pentyl)mino)1,4-dioxobutyl)ydroxyamino)entyl)n-(5-aminopentyl)-n-hydroxy-, Monomethanesulphonate

105. N'-(5-azanylpentyl)-n-[5-[[4-[5-[ethanoyl(oxidanyl)amino]pentylamino]-4-oxidanylidene-butanoyl]-oxidanyl-amino]pentyl]-n'-oxidanyl-butanediamide; Methanesulfonic Acid

106. N'-{5-[acetyl(hydroxy)amino]pentyl}-n-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-n-hydroxysuccinamide Methanesulfonate (salt)

107. N-(5-(3-((5-aminopentyl)hydroxycarbamoyl)propionamido)pentyl)-3-((5-(n-hydroxyacetamido)pentyl)carbamoyl)propionohydroxamic Acid Monomethanesulphonate (salt)

108. N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-1,4-dioxobutyl]-hydroxyamino]pentyl]-n'-(5-aminopentyl)-n'-hydroxybutanediamide; Methanesulfonic Acid

109. N1-(5-(4-((5-aminopentyl)amino)-4-oxobutanamido)pentyl)-n1-hydroxy-n4-(5-(n-hydroxyacetamido)pentyl)succinamide Methanesulfonate

110. N1-(5-aminopentyl)-n1-hydroxy-n4-(5-(n-hydroxy-4-(5-(n-hydroxyacetamido)pentylamino)-4-oxobutanamido)pentyl)succinamide Methanesulfonate

111. N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino-1,4-dioxobutyl]hydroxyamino]pentyl]-n1-(5-aminopentyl)-n1-hydroxybutanediamide Methanesulfonate

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 656.8 g/mol
Molecular Formula C26H52N6O11S
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count12
Rotatable Bond Count23
Exact Mass656.34147767 g/mol
Monoisotopic Mass656.34147767 g/mol
Topological Polar Surface Area269 Ų
Heavy Atom Count44
Formal Charge0
Complexity832
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameDeferoxamine mesylate
Drug LabelDeferoxamine mesylate for injection, USP, is an iron-chelating agent, available in vials for intramuscular, subcutaneous, and intravenous administration. Deferoxamine mesylate is supplied as vials containing 500 mg and 2 g of deferoxamine mesylate US...
Active IngredientDeferoxamine mesylate
Dosage FormInjectable
RouteInjection
Strength500mg/vial; 2gm/vial
Market StatusPrescription
CompanyFresenius Kabi Usa; Hospira; Eurohlth Intl

2 of 4  
Drug NameDesferal
PubMed HealthDeferoxamine (Injection)
Drug ClassesHeavy Metal Chelator
Drug LabelDesferal, deferoxamine mesylate USP, is an iron-chelating agent, available in vials for intramuscular, subcutaneous, and intravenous administration. Desferal is supplied as vials containing 500 mg and 2 g of deferoxamine mesylate USP in sterile, lyop...
Active IngredientDeferoxamine mesylate
Dosage FormInjectable
RouteInjection
Strength500mg/vial; 2gm/vial
Market StatusPrescription
CompanyNovartis

3 of 4  
Drug NameDeferoxamine mesylate
Drug LabelDeferoxamine mesylate for injection, USP, is an iron-chelating agent, available in vials for intramuscular, subcutaneous, and intravenous administration. Deferoxamine mesylate is supplied as vials containing 500 mg and 2 g of deferoxamine mesylate US...
Active IngredientDeferoxamine mesylate
Dosage FormInjectable
RouteInjection
Strength500mg/vial; 2gm/vial
Market StatusPrescription
CompanyFresenius Kabi Usa; Hospira; Eurohlth Intl

4 of 4  
Drug NameDesferal
PubMed HealthDeferoxamine (Injection)
Drug ClassesHeavy Metal Chelator
Drug LabelDesferal, deferoxamine mesylate USP, is an iron-chelating agent, available in vials for intramuscular, subcutaneous, and intravenous administration. Desferal is supplied as vials containing 500 mg and 2 g of deferoxamine mesylate USP in sterile, lyop...
Active IngredientDeferoxamine mesylate
Dosage FormInjectable
RouteInjection
Strength500mg/vial; 2gm/vial
Market StatusPrescription
CompanyNovartis

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Siderophores

Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994) (See all compounds classified as Siderophores.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Iron Chelator [EPC]; Iron Chelating Activity [MoA]

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R1-CEP 2000-160 - Rev 04
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2022-06-17
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Certificate Number : R1-CEP 2000-160 - Rev 04

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Olon SpA

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DEFEROXAMINE MESYLATE

NDC Package Code : 17337-0060

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Deferoxamine Mesylate

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About the Company : Teva was established in 1901. Our global headquarters are based in Israel. Today we have a portfolio of more than 3,500 medicines, and produce approximately 120 billion tablets and...

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LTD","customerCountry":"INDIA","quantity":"290.00","actualQuantity":"290","unit":"KGS","unitRateFc":"1550","totalValueFC":"522645.6","currency":"EUR","unitRateINR":"135935","date":"22-Dec-2021","totalValueINR":"39421150","totalValueInUsd":"522645.6","indian_port":"DELHI AIR","hs_no":"29280090","bill_no":"6786686","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"","customerAddress":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1651429800,"product":"DEFEROXAMINE MESYLATE USP HN","address":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR","city":"NEW DELHI","supplier":"FAREVA","supplierCountry":"GERMANY","foreign_port":"NA","customer":"STERILE INDIA PVT. LTD","customerCountry":"INDIA","quantity":"544.00","actualQuantity":"544","unit":"KGS","unitRateFc":"1550","totalValueFC":"918090.4","currency":"EUR","unitRateINR":"130432.5","date":"02-May-2022","totalValueINR":"70955280","totalValueInUsd":"918090.4","indian_port":"DELHI AIR","hs_no":"29280090","bill_no":"8512263","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1662921000,"product":"DEFEROXAMINE MESYLATE USP","address":"Part of Plot No.11 & 87, Sy No.119 Phase - IV, Extension in IP, Pasham","city":"HYDERABAD","supplier":"FAREVA","supplierCountry":"GERMANY","foreign_port":"NA","customer":"GLAND PHARMA LIMITED","customerCountry":"INDIA","quantity":"57.50","actualQuantity":"57.5","unit":"KGS","unitRateFc":"2750","totalValueFC":"160394.7","currency":"EUR","unitRateINR":"223551.3","date":"12-Sep-2022","totalValueINR":"12854196.88","totalValueInUsd":"160394.7","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"2404024","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"Part of Plot No.11 & 87, Sy No.119 Phase - IV, Extension in IP, Pasham"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1669746600,"product":"DEFEROXAMINE MESYLATE USP","address":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR","city":"NEW DELHI","supplier":"EXCELLA GMBH","supplierCountry":"GERMANY","foreign_port":"NA","customer":"STERILE INDIA PVT. LTD","customerCountry":"INDIA","quantity":"350.00","actualQuantity":"350","unit":"KGS","unitRateFc":"1550","totalValueFC":"573325.5","currency":"EUR","unitRateINR":"133687.5","date":"30-Nov-2022","totalValueINR":"46790625","totalValueInUsd":"573325.5","indian_port":"DELHI AIR","hs_no":"29280090","bill_no":"3531742","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1676053800,"product":"DEFEROXAMINE MESYLATE","address":"M-134, 2ND FLOOR CONNAUGHT CIRCUS","city":"NEW DELHI","supplier":"FLAVINE","supplierCountry":"GERMANY","foreign_port":"NA","customer":"RAJASTHAN ANTIBIOTICS","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"5500","totalValueFC":"5510.7","currency":"USD","unitRateINR":"455125","date":"11-Feb-2023","totalValueINR":"455125","totalValueInUsd":"5510.7","indian_port":"DELHI AIR","hs_no":"29280090","bill_no":"4600717","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"M-134, 2ND FLOOR CONNAUGHT CIRCUS"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1680719400,"product":"DEFEROXAMINE MESYLATE USP","address":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR","city":"NEW DELHI","supplier":"EXCELLA GMBH &CO.KG","supplierCountry":"GERMANY","foreign_port":"NA","customer":"STERILE INDIA PVT. LTD","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"1600","totalValueFC":"697759.2","currency":"EUR","unitRateINR":"142960","date":"06-Apr-2023","totalValueINR":"57184000","totalValueInUsd":"697759.2","indian_port":"DELHI AIR","hs_no":"29280090","bill_no":"5391137","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"501 5TH FLOOR AGGARWAL CORPORATE HEIGHTS PLOT NO A-7 N.S.P, PITAMPUR"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717439400,"product":"DEFEROXAMINE MESYLATE USP","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FAREVA","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"GLAND PHARMA LTD","customerCountry":"INDIA","quantity":"21.00","actualQuantity":"21","unit":"KGS","unitRateFc":"2200","totalValueFC":"51265","currency":"EUR","unitRateINR":"203789.1","date":"04-Jun-2024","totalValueINR":"4279570.31","totalValueInUsd":"51265","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"3819819","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"NUMBERGER STR 12, D-90537 FEUCHT, GERMANYSDNF Germany","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723401000,"product":"DEFEROXAMINE MESYLATE USP","address":"1705, 4TH FLOOR, ONKAR BHAWAN","city":"DELHI","supplier":"EXCELLA GMBA & CO.KG","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"STERILE INDIA PVT. LTD","customerCountry":"INDIA","quantity":"84.00","actualQuantity":"84","unit":"KGS","unitRateFc":"2145","totalValueFC":"198162.8","currency":"EUR","unitRateINR":"197876.3","date":"12-Aug-2024","totalValueINR":"16621605","totalValueInUsd":"198162.8","indian_port":"Delhi Air","hs_no":"29280090","bill_no":"5016777","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"NURNBERGER STR.12D-90537 FEUCHTGERMANY SDNF","customerAddress":"1705, 4TH FLOOR, ONKAR BHAWAN"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724610600,"product":"DEFEROXAMINE MESYLATE USP","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FAREVA","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"GLAND PHARMA LTD","customerCountry":"INDIA","quantity":"11.80","actualQuantity":"11.8","unit":"KGS","unitRateFc":"3100","totalValueFC":"40978.6","currency":"EUR","unitRateINR":"291290.1","date":"26-Aug-2024","totalValueINR":"3437223.28","totalValueInUsd":"40978.6","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"5253262","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"NUMBERGER STR 12, D-90537 FEUCHT, GERMANYSDNF Germany","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724610600,"product":"DEFEROXAMINE MESYLATE USP","address":"6-3-865\/1\/2, FLAT NO.201,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"FAREVA","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"GLAND PHARMA LTD","customerCountry":"INDIA","quantity":"53.00","actualQuantity":"53","unit":"KGS","unitRateFc":"3100","totalValueFC":"183988.6","currency":"EUR","unitRateINR":"291182.9","date":"26-Aug-2024","totalValueINR":"15432694","totalValueInUsd":"183988.6","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"5253262","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"NUMBERGER STR 12, D-90537 FEUCHT, GERMANYSDNF Germany","customerAddress":"6-3-865\/1\/2, FLAT NO.201,"}]
12-Jan-2021
27-Sep-2024
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Average Price (USD/KGS)

Number of Transactions

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Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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Drugs in Development

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Details:

Mitem acquires Desfera (deferoxamine mesylate) products from Novartis. It is indicated for treating iron overload, and forex, following blood transfusions necessary for treating beta-thalassemia.


Lead Product(s): Deferoxamine Mesylate

Therapeutic Area: Pharmacology/Toxicology Brand Name: Desfera

Study Phase: ApprovedProduct Type: Small molecule

Sponsor: Mitem Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition September 25, 2024

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Duphat
Not Confirmed
Duphat
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Details : Mitem acquires Desfera (deferoxamine mesylate) products from Novartis. It is indicated for treating iron overload, and forex, following blood transfusions necessary for treating beta-thalassemia.

Brand Name : Desfera

Molecule Type : Small molecule

Upfront Cash : Undisclosed

September 25, 2024

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Details:

The trial will investigate the company’s Deferoxamine Intradermal Drug Patch (DIDP), for the topical treatment of Sickle Cell Leg Ulcers (SCUs) in support of its Orphan Drug Designation awarded in March of 2019.


Lead Product(s): Deferoxamine Mesylate

Therapeutic Area: Genetic Disease Brand Name: Undisclosed

Study Phase: Phase I/ Phase IIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 15, 2020

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Duphat
Not Confirmed
Duphat
Not Confirmed

Details : The trial will investigate the company’s Deferoxamine Intradermal Drug Patch (DIDP), for the topical treatment of Sickle Cell Leg Ulcers (SCUs) in support of its Orphan Drug Designation awarded in March of 2019.

Brand Name : Undisclosed

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 15, 2020

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FDA Orange Book

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01

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 500MG/VIAL

Approval Date : 2006-03-31

Application Number : 76806

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

Dr Reddy Company Banner

02

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 2GM/VIAL

Approval Date : 2006-03-31

Application Number : 76806

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

Dr Reddy Company Banner

03

Duphat
Not Confirmed
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Duphat
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DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 500MG/VIAL

Approval Date : 2009-09-15

Application Number : 78718

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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Duphat
Not Confirmed
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Duphat
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DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 2GM/VIAL

Approval Date : 2009-09-15

Application Number : 78718

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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Duphat
Not Confirmed
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DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 500MG/VIAL

Approval Date : 2017-09-29

Application Number : 207384

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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Duphat
Not Confirmed
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DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 2GM/VIAL

Approval Date : 2017-09-29

Application Number : 207384

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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HOSPIRA

U.S.A
Duphat
Not Confirmed
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HOSPIRA

U.S.A
arrow
Duphat
Not Confirmed

DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 500MG/VIAL

Approval Date : 2004-03-17

Application Number : 76019

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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HOSPIRA

U.S.A
Duphat
Not Confirmed
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HOSPIRA

U.S.A
arrow
Duphat
Not Confirmed

DEFEROXAMINE MESYLATE

Brand Name : DEFEROXAMINE MESYLATE

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 2GM/VIAL

Approval Date : 2004-03-17

Application Number : 76019

RX/OTC/DISCN : RX

RLD : No

TE Code : AP

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NOVARTIS

Switzerland
Duphat
Not Confirmed
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NOVARTIS

Switzerland
arrow
Duphat
Not Confirmed

DEFEROXAMINE MESYLATE

Brand Name : DESFERAL

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 500MG/VIAL

Approval Date : 1982-01-01

Application Number : 16267

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AP

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NOVARTIS

Switzerland
Duphat
Not Confirmed
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NOVARTIS

Switzerland
arrow
Duphat
Not Confirmed

DEFEROXAMINE MESYLATE

Brand Name : DESFERAL

Dosage Form : INJECTABLE;INJECTION

Dosage Strength : 2GM/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

Approval Date : 2000-05-25

Application Number : 16267

RX/OTC/DISCN : DISCN

RLD : Yes

TE Code :

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Europe

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01

Duphat
Not Confirmed
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Duphat
Not Confirmed

Deferoxamine mesilas

Brand Name : Desferal

Dosage Form : Dry Sub

Dosage Strength : 500mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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Olon Spa

Italy
Duphat
Not Confirmed
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Olon Spa

Italy
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Brand Name :

Dosage Form : Lyophilizate

Dosage Strength : 500MG

Packaging : Vial

Approval Date :

Application Number :

Regulatory Info : Available Dossier- US-EU-RoW

Registration Country : Italy

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Olon Spa

Italy
Duphat
Not Confirmed
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Olon Spa

Italy
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Brand Name :

Dosage Form : Lyophilizate

Dosage Strength : 2000MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Orifarm AB

Denmark
Duphat
Not Confirmed
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Orifarm AB

Denmark
arrow
Duphat
Not Confirmed

deferoxaminmesilat

Brand Name : Desferin

Dosage Form : POWDER FOR INJECTION / INFUSION

Dosage Strength : 500 MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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Orifarm AB

Denmark
Duphat
Not Confirmed
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Orifarm AB

Denmark
arrow
Duphat
Not Confirmed

deferoxaminmesilat

Brand Name : Desferal

Dosage Form : POWDER FOR INJECTION / INFUSION

Dosage Strength : 500 MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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Orifarm AS

Denmark
Duphat
Not Confirmed
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Orifarm AS

Denmark
arrow
Duphat
Not Confirmed

Deferoxamine

Brand Name : Desferal

Dosage Form : Powder for injection/infusion fluid, resolution

Dosage Strength : 500 mg

Packaging : Hood glass

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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Duphat
Not Confirmed
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Duphat
Not Confirmed

deferoxaminmesilat

Brand Name : Desferal

Dosage Form : POWDER FOR INJECTION / INFUSION

Dosage Strength : 500 MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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Duphat
Not Confirmed
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Duphat
Not Confirmed

deferoxaminmesilat

Brand Name : Desferal

Dosage Form : POWDER FOR INJECTION / INFUSION

Dosage Strength : 500 MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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Medartuum AB

Country
Duphat
Not Confirmed
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Medartuum AB

Country
arrow
Duphat
Not Confirmed

deferoxaminmesilat

Brand Name : Desferal

Dosage Form : POWDER FOR INJECTION / INFUSION

Dosage Strength : 500 MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Sweden

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2care4

Country
Duphat
Not Confirmed
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2care4

Country
arrow
Duphat
Not Confirmed

Deferoxamine

Brand Name : Desferal

Dosage Form : Powder for injection/infusion fluid, resolution

Dosage Strength : 500 mg

Packaging : Hood glass

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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NEWS #PharmaBuzz

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Global Sales Information

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Finished Drug Prices

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01

Brand Name : Desferal

Switzerland
arrow
Duphat
Not Confirmed

Brand Name : Desferal

Switzerland
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Dosage Form : Dry Sub

Dosage Strength : 500mg

Price Per Pack (Euro) : 55.58

Published in :

Country : Switzerland

RX/OTC/DISCN : Class B

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Brand Name : DESFERAL

Switzerland
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Duphat
Not Confirmed

Brand Name : DESFERAL

Switzerland
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Dosage Form : Powder And Solvent For Injection

Dosage Strength : 500 mg/5 ml

Price Per Pack (Euro) : 43.59

Published in :

Country : Italy

RX/OTC/DISCN :

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Brand Name : Desferal

Denmark
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Duphat
Not Confirmed

Brand Name : Desferal

Denmark
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Dosage Form : Powder for injection/infusion fl...

Dosage Strength : 500 mg

Price Per Pack (Euro) : 58.586

Published in :

Country : Norway

RX/OTC/DISCN :

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Brand Name : Desferal

Country
arrow
Duphat
Not Confirmed

Brand Name : Desferal

Country
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Dosage Form : Powder for injection/infusion fl...

Dosage Strength : 500 mg

Price Per Pack (Euro) : 58.586

Published in :

Country : Norway

RX/OTC/DISCN :

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Brand Name : DEFEROXAMINA NORIDEM

Country
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Duphat
Not Confirmed

Brand Name : DEFEROXAMINA NORIDEM

Country
arrow
Duphat
Not Confirmed

Deferoxamine Mesylate

Dosage Form : Powder For Solution For Injectio...

Dosage Strength : 500 mg

Price Per Pack (Euro) : 43.53

Published in :

Country : Italy

RX/OTC/DISCN :

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ABOUT THIS PAGE

Deferoxamine Mesylate Manufacturers

A Deferoxamine Mesylate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Deferoxamine Mesylate, including repackagers and relabelers. The FDA regulates Deferoxamine Mesylate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Deferoxamine Mesylate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Deferoxamine Mesylate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Deferoxamine Mesylate Suppliers

A Deferoxamine Mesylate supplier is an individual or a company that provides Deferoxamine Mesylate active pharmaceutical ingredient (API) or Deferoxamine Mesylate finished formulations upon request. The Deferoxamine Mesylate suppliers may include Deferoxamine Mesylate API manufacturers, exporters, distributors and traders.

click here to find a list of Deferoxamine Mesylate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Deferoxamine Mesylate USDMF

A Deferoxamine Mesylate DMF (Drug Master File) is a document detailing the whole manufacturing process of Deferoxamine Mesylate active pharmaceutical ingredient (API) in detail. Different forms of Deferoxamine Mesylate DMFs exist exist since differing nations have different regulations, such as Deferoxamine Mesylate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Deferoxamine Mesylate DMF submitted to regulatory agencies in the US is known as a USDMF. Deferoxamine Mesylate USDMF includes data on Deferoxamine Mesylate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Deferoxamine Mesylate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Deferoxamine Mesylate suppliers with USDMF on PharmaCompass.

Deferoxamine Mesylate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Deferoxamine Mesylate Drug Master File in Japan (Deferoxamine Mesylate JDMF) empowers Deferoxamine Mesylate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Deferoxamine Mesylate JDMF during the approval evaluation for pharmaceutical products. At the time of Deferoxamine Mesylate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Deferoxamine Mesylate suppliers with JDMF on PharmaCompass.

Deferoxamine Mesylate CEP

A Deferoxamine Mesylate CEP of the European Pharmacopoeia monograph is often referred to as a Deferoxamine Mesylate Certificate of Suitability (COS). The purpose of a Deferoxamine Mesylate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Deferoxamine Mesylate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Deferoxamine Mesylate to their clients by showing that a Deferoxamine Mesylate CEP has been issued for it. The manufacturer submits a Deferoxamine Mesylate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Deferoxamine Mesylate CEP holder for the record. Additionally, the data presented in the Deferoxamine Mesylate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Deferoxamine Mesylate DMF.

A Deferoxamine Mesylate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Deferoxamine Mesylate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Deferoxamine Mesylate suppliers with CEP (COS) on PharmaCompass.

Deferoxamine Mesylate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Deferoxamine Mesylate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Deferoxamine Mesylate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Deferoxamine Mesylate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Deferoxamine Mesylate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Deferoxamine Mesylate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Deferoxamine Mesylate suppliers with NDC on PharmaCompass.

Deferoxamine Mesylate GMP

Deferoxamine Mesylate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Deferoxamine Mesylate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Deferoxamine Mesylate GMP manufacturer or Deferoxamine Mesylate GMP API supplier for your needs.

Deferoxamine Mesylate CoA

A Deferoxamine Mesylate CoA (Certificate of Analysis) is a formal document that attests to Deferoxamine Mesylate's compliance with Deferoxamine Mesylate specifications and serves as a tool for batch-level quality control.

Deferoxamine Mesylate CoA mostly includes findings from lab analyses of a specific batch. For each Deferoxamine Mesylate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Deferoxamine Mesylate may be tested according to a variety of international standards, such as European Pharmacopoeia (Deferoxamine Mesylate EP), Deferoxamine Mesylate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Deferoxamine Mesylate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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