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Synopsis

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Chemistry

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Also known as: 71771-90-9, R(-)-denopamine, Kalgut, Ta 064, Ta-064, 4-[(1r)-2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol
Molecular Formula
C18H23NO4
Molecular Weight
317.4  g/mol
InChI Key
VHSBBVZJABQOSG-INIZCTEOSA-N
FDA UNII
V5F60UPD8P

Denopamine
1 2D Structure

Denopamine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[(1R)-2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol
2.1.2 InChI
InChI=1S/C18H23NO4/c1-22-17-8-3-13(11-18(17)23-2)9-10-19-12-16(21)14-4-6-15(20)7-5-14/h3-8,11,16,19-21H,9-10,12H2,1-2H3/t16-/m0/s1
2.1.3 InChI Key
VHSBBVZJABQOSG-INIZCTEOSA-N
2.1.4 Canonical SMILES
COC1=C(C=C(C=C1)CCNCC(C2=CC=C(C=C2)O)O)OC
2.1.5 Isomeric SMILES
COC1=C(C=C(C=C1)CCNC[C@@H](C2=CC=C(C=C2)O)O)OC
2.2 Other Identifiers
2.2.1 UNII
V5F60UPD8P
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (3,4-dimethoxyphenethylaminomethyl)-4-hydroxybenzyl Alcohol

2. 1-(p-hydroxyphenyl)-2-((3,4-dimethoxyphenethyl)amino)ethanol

3. Ta 064

4. Ta-064

2.3.2 Depositor-Supplied Synonyms

1. 71771-90-9

2. R(-)-denopamine

3. Kalgut

4. Ta 064

5. Ta-064

6. 4-[(1r)-2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol

7. V5f60upd8p

8. Chembl493682

9. Denopamina

10. Denopaminum

11. 4-[(1r)-2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxy-ethyl]phenol

12. Benzenemethanol, A-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-,(ar)-

13. Denopaminum [latin]

14. Kalgut (tn)

15. Denopamina [spanish]

16. Denopamine [inn:jan]

17. Unii-v5f60upd8p

18. R()-denopamine

19. Ncgc00094384-01

20. Denopamine [mi]

21. Denopamine (jan/inn)

22. Denopamine [inn]

23. Denopamine [jan]

24. Lopac-d-7815

25. Denopamine [mart.]

26. Denopamine [who-dd]

27. Dsstox_cid_25800

28. Dsstox_rid_81138

29. Dsstox_gsid_45800

30. Gtpl534

31. Schembl218640

32. Dtxsid8045800

33. Chebi:135359

34. Bcp17423

35. Zinc1552175

36. Tox21_111272

37. Bdbm50252956

38. (-)-(r)-1-(p-hydroxyphenyl)-2-((3,4-dimethoxyphenethyl)amino)ethanol

39. Benzenemethanol, Alpha-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methyl)-4-hydroxy-, (r)-

40. Ncgc00015367-01

41. Cas-71771-90-9

42. Hy-119515

43. Cs-0068617

44. R(-)-denopamine, >=98% (hplc), Powder

45. D02614

46. Dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol

47. (r)-4-(2-(3,4-dimethoxyphenethylamino)-1-hydroxyethyl)phenol

48. 4-[(1r)-2-[2-(3,4-

49. 4-[(1r)-2-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-1-hydroxyethyl]phenol

50. (-)-(r)-.alpha.-(((3,4-dimethoxyphenethyl)amino)methyl)-p-hydroxybenzyl Alcohol

51. (-)-(r)-alpha-(((3,4-dimethoxyphenethyl)amino)methyl)-p-hydroxybenzyl Alcohol

2.4 Create Date
2005-12-16
3 Chemical and Physical Properties
Molecular Weight 317.4 g/mol
Molecular Formula C18H23NO4
XLogP31.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass317.16270821 g/mol
Monoisotopic Mass317.16270821 g/mol
Topological Polar Surface Area71 Ų
Heavy Atom Count23
Formal Charge0
Complexity320
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)


Adrenergic beta-Agonists

Drugs that selectively bind to and activate beta-adrenergic receptors. (See all compounds classified as Adrenergic beta-Agonists.)


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ABOUT THIS PAGE

Denopamine Manufacturers

A Denopamine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Denopamine, including repackagers and relabelers. The FDA regulates Denopamine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Denopamine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Denopamine Suppliers

A Denopamine supplier is an individual or a company that provides Denopamine active pharmaceutical ingredient (API) or Denopamine finished formulations upon request. The Denopamine suppliers may include Denopamine API manufacturers, exporters, distributors and traders.

click here to find a list of Denopamine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Denopamine JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Denopamine Drug Master File in Japan (Denopamine JDMF) empowers Denopamine API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Denopamine JDMF during the approval evaluation for pharmaceutical products. At the time of Denopamine JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Denopamine suppliers with JDMF on PharmaCompass.

Denopamine GMP

Denopamine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Denopamine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Denopamine GMP manufacturer or Denopamine GMP API supplier for your needs.

Denopamine CoA

A Denopamine CoA (Certificate of Analysis) is a formal document that attests to Denopamine's compliance with Denopamine specifications and serves as a tool for batch-level quality control.

Denopamine CoA mostly includes findings from lab analyses of a specific batch. For each Denopamine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Denopamine may be tested according to a variety of international standards, such as European Pharmacopoeia (Denopamine EP), Denopamine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Denopamine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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