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Chemistry

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Also known as: 77614-16-5, H-tyr-d-ala-phe-gly-tyr-pro-ser-nh2, (2s)-n-[(2s)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2s)-2-[[2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide, Chembl278789, 2sec01b703, Tyr-d-ala-phe-gly-tyr-pro-ser-nh2
Molecular Formula
C40H50N8O10
Molecular Weight
802.9  g/mol
InChI Key
FHZPGIUBXYVUOY-VWGYHWLBSA-N
FDA UNII
2SEC01B703

Dermorphin
dermorphin is a natural product found in Agalychnis callidryas with data available.
1 2D Structure

Dermorphin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
2.1.2 InChI
InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1
2.1.3 InChI Key
FHZPGIUBXYVUOY-VWGYHWLBSA-N
2.1.4 Canonical SMILES
CC(C(=O)NC(CC1=CC=CC=C1)C(=O)NCC(=O)NC(CC2=CC=C(C=C2)O)C(=O)N3CCCC3C(=O)NC(CO)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)O)N
2.1.5 Isomeric SMILES
C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CO)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)N
2.2 Other Identifiers
2.2.1 UNII
2SEC01B703
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Dermorphin, (2-l-ala)-isomer

2. H-tyr-d-ala-phe-gly-tyr-pro-ser-nh2

3. Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide

2.3.2 Depositor-Supplied Synonyms

1. 77614-16-5

2. H-tyr-d-ala-phe-gly-tyr-pro-ser-nh2

3. (2s)-n-[(2s)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2s)-2-[[2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide

4. Chembl278789

5. 2sec01b703

6. Tyr-d-ala-phe-gly-tyr-pro-ser-nh2

7. Dermorphin Acetate

8. Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide

9. Unii-2sec01b703

10. Yafgyps-nh2

11. Schembl237169

12. Tyr-ala-phe-gly-tyr-pro-ser

13. Dtxsid40228281

14. Chebi:177767

15. Hy-p0244

16. Bdbm50059841

17. Tyr-dala-phe-gly-tyr-pro-ser-nh2

18. Zinc95548678

19. C20030

20. Q1771654

21. L-serinamide, L-tyrosyl-d-alanyl-l-phenylalanylglycyl-l-tyrosyl-l-prolyl-

22. (s)-1-[(s)-2-[2-((s)-2-{(r)-2-[(s)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic Acid ((s)-1-carbamoyl-2-hydroxy-ethyl)-amide

23. (s)-n-((s)-1-amino-3-hydroxy-1-oxopropan-2-yl)-1-((2s,8s,11r,14s)-14-amino-8-benzyl-2-(4-hydroxybenzyl)-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamide

24. 1-[2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic Acid (1-carbamoyl-2-hydroxy-ethyl)-amide

25. 1-[2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic Acid (1-carbamoyl-2-hydroxy-ethyl)-amide (dermorphin)

26. 1-[2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic Acid (1-carbamoyl-2-hydroxy-ethyl)-amide(dermorphin)

27. Dermorphin;1-[2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic Acid (1-carbamoyl-2-hydroxy-ethyl)-amide

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 802.9 g/mol
Molecular Formula C40H50N8O10
XLogP30
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count11
Rotatable Bond Count19
Exact Mass802.36498982 g/mol
Monoisotopic Mass802.36498982 g/mol
Topological Polar Surface Area296 Ų
Heavy Atom Count58
Formal Charge0
Complexity1410
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)


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Looking for 77614-16-5 / Dermorphin API manufacturers, exporters & distributors?

Dermorphin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Dermorphin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Dermorphin manufacturer or Dermorphin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Dermorphin manufacturer or Dermorphin supplier.

PharmaCompass also assists you with knowing the Dermorphin API Price utilized in the formulation of products. Dermorphin API Price is not always fixed or binding as the Dermorphin Price is obtained through a variety of data sources. The Dermorphin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Dermorphin

Synonyms

77614-16-5, H-tyr-d-ala-phe-gly-tyr-pro-ser-nh2, (2s)-n-[(2s)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2s)-2-[[2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide, Chembl278789, 2sec01b703, Tyr-d-ala-phe-gly-tyr-pro-ser-nh2

Cas Number

77614-16-5

Unique Ingredient Identifier (UNII)

2SEC01B703

About Dermorphin

dermorphin is a natural product found in Agalychnis callidryas with data available.

Dermorphin Manufacturers

A Dermorphin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dermorphin, including repackagers and relabelers. The FDA regulates Dermorphin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dermorphin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Dermorphin Suppliers

A Dermorphin supplier is an individual or a company that provides Dermorphin active pharmaceutical ingredient (API) or Dermorphin finished formulations upon request. The Dermorphin suppliers may include Dermorphin API manufacturers, exporters, distributors and traders.

click here to find a list of Dermorphin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Dermorphin USDMF

A Dermorphin DMF (Drug Master File) is a document detailing the whole manufacturing process of Dermorphin active pharmaceutical ingredient (API) in detail. Different forms of Dermorphin DMFs exist exist since differing nations have different regulations, such as Dermorphin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Dermorphin DMF submitted to regulatory agencies in the US is known as a USDMF. Dermorphin USDMF includes data on Dermorphin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Dermorphin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Dermorphin suppliers with USDMF on PharmaCompass.

Dermorphin GMP

Dermorphin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Dermorphin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dermorphin GMP manufacturer or Dermorphin GMP API supplier for your needs.

Dermorphin CoA

A Dermorphin CoA (Certificate of Analysis) is a formal document that attests to Dermorphin's compliance with Dermorphin specifications and serves as a tool for batch-level quality control.

Dermorphin CoA mostly includes findings from lab analyses of a specific batch. For each Dermorphin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Dermorphin may be tested according to a variety of international standards, such as European Pharmacopoeia (Dermorphin EP), Dermorphin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dermorphin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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