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1. 131-01-1
2. Harmonyl
3. Raunormine
4. Recanescin
5. Deserpidin
6. Recanescine
7. Canescine
8. Desepridine
9. Raunormin
10. Canescin
11. Desmethoxyreserpine
12. 11-demethoxyreserpine
13. 11-desmethoxyreserpine
14. Deserpidinum [inn-latin]
15. Deserpidina [inn-spanish]
16. Reserpidine
17. Halmonyl
18. Tranquinil
19. Deresperine
20. Deserpidine (inn)
21. Chebi:27478
22. Deserpidine, (-)-
23. Deserpidic Acid, Methyl Ester, 3,4,5-trimethoxybenzoate
24. Lilly 22641
25. Nsc72138
26. Nsc-72138
27. Methyl (1r,15s,17r,18r,19s,20s)-18-methoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
28. Methyl (3beta,16beta,17alpha,18beta,20alpha)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
29. 9016e3vb47
30. Ncgc00168786-01
31. Ncgc00168786-02
32. Deserpidina
33. Deserpidinum
34. Dsstox_cid_383
35. Deserpidine [inn]
36. Nsc 72138
37. A-11025
38. Deserpidine [inn:ban]
39. Dsstox_rid_75556
40. Dsstox_gsid_20383
41. (3beta,16beta,17alpha,18beta,20alpha)-17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester
42. Methyl (3beta,16beta,17alpha,18beta,20alpha)-17-(methyloxy)-18-({[3,4,5-tris(methyloxy)phenyl]carbonyl}oxy)yohimban-16-carboxylate
43. Yohimban-16-carboxylic Acid,17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, Methyl Ester,(3b,16b,17a,18b,20a)-
44. Halmonyl (tn)
45. Cas-131-01-1
46. Einecs 205-004-8
47. Brn 0101820
48. Unii-9016e3vb47
49. Md-0232
50. Methyl 17alpha-methoxy-18beta-(3,4,5-trimethoxybenzoyloxy)-3beta,20alpha-yohimban-16beta-carboxylat
51. Methyl 18beta-hydroxy-17alpha-methoxy-3beta,20alpha-yohimban-16beta-carboxylate, 3,4,5-trimethoxybenzoate (ester)
52. Deserpidine [mi]
53. Deserpidine [vandf]
54. Deserpidine [mart.]
55. Deserpidine [who-dd]
56. 3-beta,20-alpha-yohimban-16-beta-carboxylic Acid, 18-beta-hydroxy-17-alpha-methoxy-, Methyl Ester, 3,4,5-trimethoxybenzoate (ester)
57. 4-25-00-01282 (beilstein Handbook Reference)
58. Methyl 17alpha-methoxy-18beta-((3,4,5-trimethoxybenzoyl)oxy)-3beta,20alpha-yohimban-16beta-carboxylate
59. Mls006010113
60. Schembl259343
61. Gtpl7064
62. Chembl1200515
63. Dtxsid8020383
64. Deserpidine [orange Book]
65. Methyl 17.alpha.-methoxy-18.beta.-((3,4,5-trimethoxybenzoyl)oxy)-3.beta.,20.alpha.-yohimban-16.beta.-carboxylate
66. Methyl 18.beta.-hydroxy-17.alpha.-methoxy-3.beta.,20.alpha.-yohimban-16.beta.-carboxylate, 3,4,5-trimethoxybenzoate (ester)
67. Zinc4097186
68. Tox21_112646
69. Tox21_113102
70. Bdbm50480272
71. Enduronyl Component Deserpidine
72. Akos015896464
73. Db01089
74. Deserpidine Component Of Enduronyl
75. (1s,2r,3r,4as,13br,14as)-methyl 2-methoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
76. 17.alpha.-methoxy-18.beta.-[(3,4,5-trimethoxybenzoyl)oxy]-3.beta.,20.alpha.-yohimban-16.beta.-carboxylic Acid Methyl Ester
77. Smr004701248
78. Oreticyl Forte Component Deserpidine
79. Hy-107339
80. Cs-0028177
81. Deserpidine Component Of Oreticyl Forte
82. C06541
83. D08194
84. 131d011
85. J-005923
86. Q5263885
87. Benz[g]indolo[2, 1,2,3,4,4a,5,7,8,-13,13b,14,14a-dodecahydro-3-hydroxy-2-methoxy-, Methyl Ester, 3,4,5-trimethoxybenzoate
88. Methyl (1r,15s,17r,18r,19s,20s)-18-methoxy-17-[(3,4,5-trimethoxyphenyl)carbonyloxy]-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
89. Yohimban-16-carboxylic Acid, 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, Methyl Ester, (3b,16b,17a,18b,20a)-
| Molecular Weight | 578.7 g/mol |
|---|---|
| Molecular Formula | C32H38N2O8 |
| XLogP3 | 4.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 9 |
| Exact Mass | 578.26281617 g/mol |
| Monoisotopic Mass | 578.26281617 g/mol |
| Topological Polar Surface Area | 109 Ų |
| Heavy Atom Count | 42 |
| Formal Charge | 0 |
| Complexity | 953 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 6 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
For the treatment of hypertension.
Deserpidine, an alkaloid of Rauwolfia canescens, is used as an antihypertensive. Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure.
C - Cardiovascular system
C02 - Antihypertensives
C02A - Antiadrenergic agents, centrally acting
C02AA - Rauwolfia alkaloids
C02AA05 - Deserpidine
Deserpidine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. The neurotransmitters that are not sequestered in the storage vesicle are readily metabolized by monoamine oxidase (MAO) causing a reduction in catecholamines.
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A Deserpidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Deserpidine, including repackagers and relabelers. The FDA regulates Deserpidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Deserpidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Deserpidine supplier is an individual or a company that provides Deserpidine active pharmaceutical ingredient (API) or Deserpidine finished formulations upon request. The Deserpidine suppliers may include Deserpidine API manufacturers, exporters, distributors and traders.
click here to find a list of Deserpidine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Deserpidine DMF (Drug Master File) is a document detailing the whole manufacturing process of Deserpidine active pharmaceutical ingredient (API) in detail. Different forms of Deserpidine DMFs exist exist since differing nations have different regulations, such as Deserpidine USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Deserpidine DMF submitted to regulatory agencies in the US is known as a USDMF. Deserpidine USDMF includes data on Deserpidine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Deserpidine USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Deserpidine suppliers with USDMF on PharmaCompass.
Deserpidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Deserpidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Deserpidine GMP manufacturer or Deserpidine GMP API supplier for your needs.
A Deserpidine CoA (Certificate of Analysis) is a formal document that attests to Deserpidine's compliance with Deserpidine specifications and serves as a tool for batch-level quality control.
Deserpidine CoA mostly includes findings from lab analyses of a specific batch. For each Deserpidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Deserpidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Deserpidine EP), Deserpidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Deserpidine USP).
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