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Chemistry

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Also known as: O-desmethyl tramadol, (+)-o-desmethyltramadol, 80456-81-1, Desmetramadol, Mono-o-demethyltramadol, (+)-o-demethyltramadol
Molecular Formula
C15H23NO2
Molecular Weight
249.35  g/mol
InChI Key
UWJUQVWARXYRCG-HIFRSBDPSA-N
FDA UNII
9W28LW2ET5

Desmetramadol
1 2D Structure

Desmetramadol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[(1R,2R)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol
2.1.2 InChI
InChI=1S/C15H23NO2/c1-16(2)11-13-6-3-4-9-15(13,18)12-7-5-8-14(17)10-12/h5,7-8,10,13,17-18H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1
2.1.3 InChI Key
UWJUQVWARXYRCG-HIFRSBDPSA-N
2.1.4 Canonical SMILES
CN(C)CC1CCCCC1(C2=CC(=CC=C2)O)O
2.1.5 Isomeric SMILES
CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)O)O
2.2 Other Identifiers
2.2.1 UNII
9W28LW2ET5
2.3 Synonyms
2.3.1 MeSH Synonyms

1. O-demethyl Tramadol

2. O-demethyltramadol

3. O-demethyltramadol Hydrochloride

4. Tramadol M1 Metabolite

2.3.2 Depositor-Supplied Synonyms

1. O-desmethyl Tramadol

2. (+)-o-desmethyltramadol

3. 80456-81-1

4. Desmetramadol

5. Mono-o-demethyltramadol

6. (+)-o-demethyltramadol

7. Desmetramadol, Cis-(+)-

8. Chembl1400

9. Desmetramadol, R,r-(+)-

10. 2wa8f50c3f

11. 9w28lw2et5

12. 3-((1r,2r)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol

13. Phenol, 3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, Cis-(+/-)-

14. 144830-14-8

15. O-dsmt

16. Chembl201556

17. Phenol, 3-((1r,2r)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-

18. 3-[(1r,2r)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]phenol

19. Phenol, 3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, (1r-cis)-

20. Tramadol M1 Metabolite

21. Unii-2wa8f50c3f

22. 3-{(1r,2r)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl}phenol

23. Desmetramadol [inn]

24. Unii-9w28lw2et5

25. Desmetramadol [who-dd]

26. Schembl2517055

27. Chebi:165221

28. Dtxsid401044548

29. Dtxsid901313651

30. 80456-81-1 (free Base)

31. Zinc2509756

32. Bdbm50176258

33. Bdbm50176263

34. Akos030241093

35. Ncgc00165941-01

36. Q63395330

37. Tramadol Hydrochloride Impurity D [ep Impurity]

38. 3-[(1r,2r)-2-[(dimethylamino)methyl]-1-hydroxy-cyclohexyl]phenol

39. (rr,ss)-3-(2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol

40. Rel-3-((1r,2r)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol

41. Phenol, 3-((1r,2r)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)-, Rel-

42. Rac-3-((1r,2r)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenolc

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 249.35 g/mol
Molecular Formula C15H23NO2
XLogP32.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass249.172878976 g/mol
Monoisotopic Mass249.172878976 g/mol
Topological Polar Surface Area43.7 Ų
Heavy Atom Count18
Formal Charge0
Complexity269
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)


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ABOUT THIS PAGE

Desmetramadol Manufacturers

A Desmetramadol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Desmetramadol, including repackagers and relabelers. The FDA regulates Desmetramadol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Desmetramadol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Desmetramadol Suppliers

A Desmetramadol supplier is an individual or a company that provides Desmetramadol active pharmaceutical ingredient (API) or Desmetramadol finished formulations upon request. The Desmetramadol suppliers may include Desmetramadol API manufacturers, exporters, distributors and traders.

Desmetramadol GMP

Desmetramadol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Desmetramadol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Desmetramadol GMP manufacturer or Desmetramadol GMP API supplier for your needs.

Desmetramadol CoA

A Desmetramadol CoA (Certificate of Analysis) is a formal document that attests to Desmetramadol's compliance with Desmetramadol specifications and serves as a tool for batch-level quality control.

Desmetramadol CoA mostly includes findings from lab analyses of a specific batch. For each Desmetramadol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Desmetramadol may be tested according to a variety of international standards, such as European Pharmacopoeia (Desmetramadol EP), Desmetramadol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Desmetramadol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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