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ACTIVE PHARMA INGREDIENTS

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2 RELATED EXCIPIENT COMPANIES

2EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 90038-01-0, Detomidine hcl, Domosedan, Mpv-253 aii, Detomidine hydrochloride [usan], Detomidine (hydrochloride)
Molecular Formula
C12H15ClN2
Molecular Weight
222.71  g/mol
InChI Key
OIWRDXKNDCJZSM-UHFFFAOYSA-N
FDA UNII
95K4LKB6QE

Detomidine
1 2D Structure

Detomidine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[(2,3-dimethylphenyl)methyl]-1H-imidazole;hydrochloride
2.1.2 InChI
InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H
2.1.3 InChI Key
OIWRDXKNDCJZSM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=CC=C1)CC2=CN=CN2)C.Cl
2.2 Other Identifiers
2.2.1 UNII
95K4LKB6QE
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Detomidine

2. Detomidine Monohydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 90038-01-0

2. Detomidine Hcl

3. Domosedan

4. Mpv-253 Aii

5. Detomidine Hydrochloride [usan]

6. Detomidine (hydrochloride)

7. 5-(2,3-dimethylbenzyl)-1h-imidazole Hydrochloride

8. 5-[(2,3-dimethylphenyl)methyl]-1h-imidazole Hydrochloride

9. 4-(2,3-dimethylbenzyl)imidazole Monohydrochloride

10. 95k4lkb6qe

11. 1h-imidazole, 4-[(2,3-dimethylphenyl)methyl]-, Monohydrochloride

12. 4-(2,3-dimethylbenzyl)-1h-imidazole Hydrochloride

13. Mfcd17292784

14. 1h-imidazole, 4-((2,3-dimethylphenyl)methyl)-, Monohydrochloride

15. 5-(2,3-dimethylbenzyl)imidazole Hydrochloride

16. Dsstox_cid_28587

17. Dsstox_rid_82858

18. 4-(2,3-dimethylbenzyl)-1h-imidazole Hcl

19. Dsstox_gsid_48661

20. Detomidine Hydrochloride (usan)

21. 5-[(2,3-dimethylphenyl)methyl]-1h-imidazole;hydrochloride

22. Cas-90038-01-0

23. Ncgc00182057-02

24. Unii-95k4lkb6qe

25. 4-[(2,3-dimethylphenyl)methyl]-1h-imidazole;hydrochloride

26. 4-(2',3'-dimethylbenzyl)imidazole Hydrochloride

27. 4-((2,3-dimethylphenyl)methyl)-1h-imidazole Hydrochloride

28. Schembl203174

29. Chembl2106210

30. Dtxsid7048661

31. Hy-b0163a

32. Amy6987

33. Bcp06805

34. Tox21_113020

35. Ac-309

36. Detomidine Hydrochloride [mi]

37. S2092

38. Akos024464193

39. Akos025149295

40. Tox21_113020_1

41. As-2744

42. Ccg-266742

43. Cs-1996

44. Sb39723

45. Detomidine Hydrochloride [mart.]

46. Ncgc00182057-03

47. Sy046831

48. D4331

49. Detomidine Hydrochloride [green Book]

50. Ft-0666296

51. Sw219456-1

52. D03702

53. 4-[(2,3-dimethylbenzyl)]imidazole Hydrochloride

54. 038d010

55. 5-[(2,3-dimethylphenyl)methyl]-1h-imidazole Hcl

56. A854060

57. Detomidine Hydrochloride For Veterinary Use

58. 4-(2'',3''-dimethylbenzyl)imidazole Hydrochloride

59. J-516575

60. Q27271799

61. 4-(2,3-dimethylbenzyl)-1h-imidazole Hydrochloride (1:1)

62. 4-[(2,3-dimethylphenyl)methyl]-3h-imidazole Hydrochloride

63. Detomidine Hydrochloride For Veterinary Use [ep Monograph]

64. Detomidine Hydrochloride; Mpv-253 Hcl; Mpv 253 Hcl; Mpv253 Hcl

65. 4-[(2,3-dimethylphenyl)methyl]-1h-imidazole Monohydrochloride;detomidine Hcl

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 222.71 g/mol
Molecular Formula C12H15ClN2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass222.0923762 g/mol
Monoisotopic Mass222.0923762 g/mol
Topological Polar Surface Area28.7 Ų
Heavy Atom Count15
Formal Charge0
Complexity181
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic alpha-2 Receptor Agonists

Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Agonists.)


Hypnotics and Sedatives

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)


Analgesics

Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)


API Reference Price

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08-Feb-2021
26-Sep-2024
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ABOUT THIS PAGE

Detomidine Manufacturers

A Detomidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Detomidine, including repackagers and relabelers. The FDA regulates Detomidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Detomidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Detomidine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Detomidine Suppliers

A Detomidine supplier is an individual or a company that provides Detomidine active pharmaceutical ingredient (API) or Detomidine finished formulations upon request. The Detomidine suppliers may include Detomidine API manufacturers, exporters, distributors and traders.

click here to find a list of Detomidine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Detomidine CEP

A Detomidine CEP of the European Pharmacopoeia monograph is often referred to as a Detomidine Certificate of Suitability (COS). The purpose of a Detomidine CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Detomidine EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Detomidine to their clients by showing that a Detomidine CEP has been issued for it. The manufacturer submits a Detomidine CEP (COS) as part of the market authorization procedure, and it takes on the role of a Detomidine CEP holder for the record. Additionally, the data presented in the Detomidine CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Detomidine DMF.

A Detomidine CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Detomidine CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Detomidine suppliers with CEP (COS) on PharmaCompass.

Detomidine NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Detomidine as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Detomidine API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Detomidine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Detomidine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Detomidine NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Detomidine suppliers with NDC on PharmaCompass.

Detomidine GMP

Detomidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Detomidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Detomidine GMP manufacturer or Detomidine GMP API supplier for your needs.

Detomidine CoA

A Detomidine CoA (Certificate of Analysis) is a formal document that attests to Detomidine's compliance with Detomidine specifications and serves as a tool for batch-level quality control.

Detomidine CoA mostly includes findings from lab analyses of a specific batch. For each Detomidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Detomidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Detomidine EP), Detomidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Detomidine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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