Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake. (See all compounds classified as Dopamine Uptake Inhibitors.)

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)

Molecular Formula	C₁₄H₂₀ClNO₂
Molecular Weight	269.77 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	269.1182566 g/mol
Monoisotopic Mass	269.1182566 g/mol
Topological Polar Surface Area	38.3 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	249
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

1 of 6
Drug Name	Dexmethylphenidate hydrochloride
Drug Label	Focalin (dexmethylphenidate hydrochloride) is the d-threo-enantiomer of racemic methylphenidate hydrochloride, which is a 50/50 mixture of the d-threo and l-threo-enantiomers. Focalin is a central nervous system (CNS) stimulant, available in 3 tabl...
Active Ingredient	Dexmethylphenidate hydrochloride
Dosage Form	Tablet; Capsule, extended release
Route	oral; Oral
Strength	2.5mg; 5mg; 25mg; 30mg; 10mg; 15mg; 40mg; 20mg
Market Status	Tentative Approval; Prescription
Company	Watson Labs; Mylan Pharms; Teva Pharms; Intellipharmaceutics; Teva Pharms Usa

2 of 6
Drug Name	Focalin
PubMed Health	Dexmethylphenidate (By mouth)
Drug Classes	CNS Stimulant
Drug Label	Focalin (dexmethylphenidate hydrochloride) is the d-threo-enantiomer of racemic methylphenidate hydrochloride, which is a 50/50 mixture of the d-threo and l-threo-enantiomers. Focalin is a central nervous system (CNS) stimulant, available in 3 tabl...
Active Ingredient	Dexmethylphenidate hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	2.5mg; 5mg; 10mg
Market Status	Prescription
Company	Novartis

3 of 6
Drug Name	Focalin xr
PubMed Health	Dexmethylphenidate (By mouth)
Drug Classes	CNS Stimulant
Drug Label	Focalin XR is an extended-release formulation of dexmethylphenidate with a bi-modal release profile. Focalin XR uses the proprietary SODAS (Spheroidal Oral Drug Absorption System) technology. Each bead-filled Focalin XR capsule contains half the dose...
Active Ingredient	Dexmethylphenidate hydrochloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	25mg; 30mg; 15mg; 5mg; 10mg; 40mg; 20mg; 35mg
Market Status	Prescription
Company	Novartis

4 of 6
Drug Name	Dexmethylphenidate hydrochloride
Drug Label	Focalin (dexmethylphenidate hydrochloride) is the d-threo-enantiomer of racemic methylphenidate hydrochloride, which is a 50/50 mixture of the d-threo and l-threo-enantiomers. Focalin is a central nervous system (CNS) stimulant, available in 3 tabl...
Active Ingredient	Dexmethylphenidate hydrochloride
Dosage Form	Tablet; Capsule, extended release
Route	oral; Oral
Strength	2.5mg; 5mg; 25mg; 30mg; 10mg; 15mg; 40mg; 20mg
Market Status	Tentative Approval; Prescription
Company	Watson Labs; Mylan Pharms; Teva Pharms; Intellipharmaceutics; Teva Pharms Usa

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

12 API Suppliers

8 USDMF

9 NDC API

7 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

30 Drugs in Development

INTERMEDIATES

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

120 FDF Dossiers

112 FDA Orange Book

8 Europe

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 10MG

TABLET;ORAL - 2.5MG

TABLET;ORAL - 5MG

CAPSULE, EXTENDED RELEASE;ORAL - 10MG

CAPSULE, EXTENDED RELEASE;ORAL - 15MG

CAPSULE, EXTENDED RELEASE;ORAL - 20MG

CAPSULE, EXTENDED RELEASE;ORAL - 25MG

CAPSULE, EXTENDED RELEASE;ORAL - 30MG

CAPSULE, EXTENDED RELEASE;ORAL - 35MG

CAPSULE, EXTENDED RELEASE;ORAL - 40MG

CAPSULE, EXTENDED RELEASE;ORAL - 5MG

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EXCIPIENTS BY APPLICATIONS

72 Fillers, Diluents & Binders

69 Coating Systems & Additives

50 Controlled & Modified Release

28 Direct Compression

27 Thickeners and Stabilizers