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    Chemistry

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    Also known as: Dl-amphetamine sulfate, Amphetamine sulphate, Phenaminum, 60-13-9, Amphamine sulfate, Amphetamini sulfas
    Molecular Formula
    C18H28N2O4S
    Molecular Weight
    368.5  g/mol
    InChI Key
    PYHRZPFZZDCOPH-UHFFFAOYSA-N
    FDA UNII
    6DPV8NK46S
    Amphetamine
    Amphetamine Sulfate is the sulfate salt form of amphetamine, a synthetic substance related to natural sympathomimetic amines. Amphetamine appears to exert its central nervous system (CNS) and peripheral effects indirectly by inducing the release of biogenic amines from their storage sites in nerve terminals. This agent is a commonly abused psychostimulant drug, which may be snorted, taken orally, smoked, or injected. Amphetamine induces psychologic dependence which is manifested by elevated mood, increased wakefulness, concentration, physical performance and a feeling of well-being. With sustained use, the effects of tachycardia and enhanced alertness diminish while psychotoxic effects such as hallucinations and delusions may occur. (NCI04)
    1 2D Structure

    Amphetamine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-phenylpropan-2-amine;sulfuric acid
    2.1.2 InChI
    InChI=1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)
    2.1.3 InChI Key
    PYHRZPFZZDCOPH-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CC1=CC=CC=C1)N.CC(CC1=CC=CC=C1)N.OS(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    6DPV8NK46S
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Dl-amphetamine Sulfate

    2. Amphetamine Sulphate

    3. Phenaminum

    4. 60-13-9

    5. Amphamine Sulfate

    6. Amphetamini Sulfas

    7. Dl-phenamine Sulfate

    8. Dl-amphetamine Sulphate

    9. Amphetaminium Sulfuricum

    10. Desoxynorephedrine Sulfate

    11. (+-)-amphetamine Sulfate

    12. Dl-amphetamine Hydrogen Sulfate

    13. (+-)-phenisopropylamine Sulfate

    14. Amfetamine Sulfate

    15. Amphetamine Sulfate [usp]

    16. Dl-1-phenyl-2-aminopropane Sulfate

    17. (+-)-2-amino-1-phenylpropane Sulfate

    18. (+-)-alpha-methylphenethylamine Sulfate (2:1)

    19. 6dpv8nk46s

    20. 1-phenylpropan-2-amine Sulfate (2:1)

    21. Amphetamine Sulfate (usp)

    22. Fenopromin Sulfate

    23. Penamine (van)

    24. Ccris 3644

    25. 1-phenyl-2-aminopropane Sulfate

    26. Cerm 1767

    27. Razemisches Phenylaminopropansulfat

    28. Dl-alpha-methylphenethylamine Sulfate

    29. Einecs 200-457-8

    30. Unii-6dpv8nk46s

    31. Nsc 170999

    32. Dl-amphetamine Sulfate Salt

    33. Benzadrine

    34. Alpha-methylphenethylamine Sulfate, (+-)-

    35. Benzedrine (tn)

    36. Evekeo (tn)

    37. Evekeo Odt

    38. Rac-amphetamine Sulphate

    39. D-amphetamine Sulfate Salt

    40. Schembl41204

    41. Amphetamine Sulfate [mi]

    42. Dtxsid4020082

    43. Phenethylamine, Alpha-methyl-, Sulfate (2:1), (+-)-

    44. Chebi:51063

    45. Amfetamine Sulfate [mart.]

    46. Amphetamine Sulfate [vandf]

    47. Amfetamine Sulfate [who-dd]

    48. Bis{1-phenylpropan-2-amine} Sulfate

    49. Amfetamine Sulfate [ep Impurity]

    50. Amfetamine Sulfate [ep Monograph]

    51. Amphetamine Sulfate [orange Book]

    52. .beta.-phenylisopyropylaminesulfate

    53. Benzeneethanamine, Alpha-methyl-, Sulfate

    54. Amphetamine Sulfate [usp Monograph]

    55. Amfetamine Sulfate [incb:green List]

    56. Delcobese Component Amphetamine Sulfate

    57. D02074

    58. (+/-)-2-amino-1-phenylpropane Sulfate

    59. (+/-)-2-amino-1-phenylpropane Sulphate

    60. Amphetamine Sulfate Component Of Delcobese

    61. Q21270844

    62. (+/-)-.alpha.-methylphenethylamine Sulfate (2:1)

    63. (+/-)-.alpha.-methylphenethylamine Sulphate (2:1)

    64. Benzeneethanamine, .alpha.-methyl-, Sulfate (2:1), (+/-)-

    65. Benzeneethanamine, .alpha.-methyl-, Sulphate (2:1), (+/-)-

    66. Dl-amphetamine Sulfate Salt Solution, Drug Standard, 1.0 Mg/ml In Methanol

    67. 2-(tetrahydro-furan-2-yl)-n-(3-trifluoromethyl-phenyl)-succinamicacid

    68. 156-31-0

    2.3.2 Other Synonyms

    1. Amfetamine

    2. Mydrial

    3. Desoxynorephedrine

    4. L Amphetamine

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 368.5 g/mol
    Molecular Formula C18H28N2O4S
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count4
    Exact Mass368.17697855 g/mol
    Monoisotopic Mass368.17697855 g/mol
    Topological Polar Surface Area135 Ų
    Heavy Atom Count25
    Formal Charge0
    Complexity166
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3

    API SUPPLIERS

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    01

    Veranova

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    DMF Number : 14783

    Submission : 2000-03-17

    Status : Active

    Type : II

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    NDC Package Code : 49812-0058

    Start Marketing Date : 1999-01-01

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    Veranova

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    DMF Number : 15089

    Submission : 2000-10-13

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    NDC Package Code : 49812-0058

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    NDC Package Code : 49812-0058

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    DMF Review : Reviewed

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    DMF Number : 24048

    Submission : 2010-07-08

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    NDC Package Code : 49812-0058

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    Siegfried AG

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    Siegfried AG

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    DMF Review : Reviewed

    Rev. Date : 2016-08-04

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    DMF Number : 29601

    Submission : 2016-02-25

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    Siegfried AG

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    Siegfried AG

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    DMF Review : Reviewed

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    Siegfried AG

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    DMF Review : Reviewed

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    Mallinckrodt Pharmaceuticals

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    Mallinckrodt Pharmaceuticals

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    DMF Review : Reviewed

    Rev. Date : 2013-03-17

    Pay. Date : 2013-03-11

    DMF Number : 15385

    Submission : 2001-04-18

    Status : Active

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    Certificate Number : R0-CEP 2020-076 - Rev 00

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    Substance Number : 2752

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    NDC Package Code : 0406-1950

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    Mallinckrodt Pharmaceuticals

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    Mallinckrodt Pharmaceuticals

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    GDUFA

    DMF Review : Reviewed

    Rev. Date : 2013-06-08

    Pay. Date : 2013-05-31

    DMF Number : 15425

    Submission : 2001-05-09

    Status : Active

    Type : II

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    SIGMA TAU

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    SIGMA TAU

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    USDMF Inactive-api
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    GDUFA

    DMF Review : N/A

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    Submission : 1984-02-09

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    API Reference Price

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    14-Feb-2022
    16-Sep-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

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    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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