menu
    • menu

    Find Dibasic Calcium Phosphate Dihydrate manufacturers, exporters & distributors on PharmaCompass

    DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

    Virtual Booth

    Contact Supplier

    Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    With Fermion, start the journey of your innovative API.

    Virtual Booth

    Contact Supplier

    Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    MARKET PLACE

    PharmaCompass

    Synopsis

    Product SearchProduct Search

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    9

    API Suppliers

    API Suppliers

    5

    USDMF

    US DMFs Filed

    0

    CEP/COS

    CEP/COS Certifications

    1

    JDMF

    JDMFs Filed

    0

    EU WC

    EU WC

    0

    KDMF

    KDMF

    1

    NDC API

    NDC API

    0

    VMF

    NDC API

    3

    Listed Suppliers

    Other Suppliers

    API REF. PRICE (USD/KG)

    $
    $ 0

    MARKET PLACE

    1

    API

    0

    FDF

    0INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    1

    FDF Dossiers

    FDF Dossiers

    0

    FDA Orange Book

    FDA (Orange Book)

    0

    Europe

    Europe

    0

    Canada

    Canada

    0

    Australia

    Australia

    0

    South Africa

    South Africa

    1

    Listed Dossiers

    Listed Dossiers

    0 DRUGS IN DEVELOPMENT

    FDF Dossiers

    DRUG PRODUCT COMPOSITIONS

    REF. STANDARDS OR IMPURITIES

    0

    EDQM

    0

    USP

    0

    JP

    0

    Others

    PATENTS & EXCLUSIVITIES

    0

    US Patents

    0

    US Exclusivities

    0

    Health Canada Patents

    DIGITAL CONTENT

    1

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    0

    News #PharmaBuzz

    GLOBAL SALES INFORMATION

    US Medicaid

    NA

    Annual Reports

    NA

    Finished Drug Prices

    NA

    108 RELATED EXCIPIENT COMPANIES

    178EXCIPIENTS BY APPLICATIONS

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: 7789-77-7, Calcium hydrogenphosphate dihydrate, Dicalcium phosphate dihydrate, Calcium monohydrogen phosphate dihydrate, 14567-92-1, Dibasic calcium phosphate dihydrate
    Molecular Formula
    CaH5O6P
    Molecular Weight
    172.09  g/mol
    InChI Key
    XAAHAAMILDNBPS-UHFFFAOYSA-L
    FDA UNII
    O7TSZ97GEP
    Dibasic Calcium Phosphate Dihydrate
    1 2D Structure

    Dibasic Calcium Phosphate Dihydrate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    calcium;hydrogen phosphate;dihydrate
    2.1.2 InChI
    InChI=1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2
    2.1.3 InChI Key
    XAAHAAMILDNBPS-UHFFFAOYSA-L
    2.1.4 Canonical SMILES
    O.O.OP(=O)([O-])[O-].[Ca+2]
    2.2 Other Identifiers
    2.2.1 UNII
    O7TSZ97GEP
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Brushite

    2. Calcium Monohydrogen Phosphate Dihydrate

    3. Calcium Phosphate, Dibasic

    4. Calcium Phosphate, Dibasic, Dihydrate

    5. Calcium Phosphate, Dihydrate (1:1)

    6. Dibasic Calcium Phosphate Dihydrate

    7. Dicalcium Phosphate

    8. Dicalcium Phosphate Anhydrous

    9. Dicalcium Phosphate Dihydrate

    2.3.2 Depositor-Supplied Synonyms

    1. 7789-77-7

    2. Calcium Hydrogenphosphate Dihydrate

    3. Dicalcium Phosphate Dihydrate

    4. Calcium Monohydrogen Phosphate Dihydrate

    5. 14567-92-1

    6. Dibasic Calcium Phosphate Dihydrate

    7. Calcium Phosphate, Dibasic, Dihydrate

    8. Calciumhydrogenphosphatedihydrate

    9. D.c.p.

    10. Calcium Phosphate Dibasic Dihydrate

    11. Calcium;hydrogen Phosphate;dihydrate

    12. Calcium Phosphate Dihydrate, Dibasic

    13. O7tsz97gep

    14. Phosphoric Acid, Calcium Salt (1:1), Dihydrate

    15. Dibasic Calcium Phosphate Hydrate

    16. Calcium Phosphate Dibasic, Hydrous

    17. Calcium Phosphate, Dibasic, Hydrous

    18. Brushite

    19. Aksepillen

    20. Eunova

    21. Unii-o7tsz97gep

    22. Brushite (ca(hpo4).2h2o)

    23. Calcium-hydrogenphosphat-2-wasser

    24. Calster (tn)

    25. Cahpo4.2h2o

    26. Calcium Phosphate Dihydrate, Dibasic [usp:jan]

    27. Calcium Phosphate, Gel (aged)

    28. Chebi:4496

    29. Dibasic Calcium Phosphate (tn)

    30. Dtxsid90872536

    31. Mfcd00149621

    32. Akos015855298

    33. Db14481

    34. Calcium Hydrogenphosphate Dihydrate,(s)

    35. Calcium Hydrogenphosphate--water (1/2)

    36. Calcium Hydrogenphosphate Dihydrate, 98%

    37. Dibasic Calcium Phosphate Hydrate (jp17)

    38. Dicalcium Phosphate Dihydrate [inci]

    39. Calcium Phosphate Dihydrate [who-dd]

    40. Calcium Phosphate, Dihydrate (1:1)

    41. Calcium Phosphate, Dihydrate, Dibasic (usp)

    42. Ft-0623398

    43. D00937

    44. Dibasic Calcium Phosphate Hydrate [jan]

    45. Calcium Phosphate, Dibasic, Dihydrate [ii]

    46. Calcium Hydrogen Phosphate Dehydrate [who-ip]

    47. Calcii Hydrogenophosphas Dihydrate [who-ip Latin]

    48. Calcium Hydrogen Phosphate Dihydrate [ep Monograph]

    49. Calcium Hydrogenphosphate Dihydrate, P.a., 98.0-105.0%

    50. Calcium Hydrogenphosphate Dihydrate, Vetec(tm) Reagent Grade

    51. Calcium Phosphate Dihydrate, Dibasic [usp Impurity]

    52. Dibasic Calcium Phosphate Dihydrate [usp Monograph]

    53. Calcium Phosphate Dibasic Dihydrate, Puriss., Meets Analytical Specification Of Ph. Eur., Bp, Usp, 98-102.5%

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 172.09 g/mol
    Molecular Formula CaH5O6P
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count0
    Exact Mass171.9449657 g/mol
    Monoisotopic Mass171.9449657 g/mol
    Topological Polar Surface Area85.4 Ų
    Heavy Atom Count8
    Formal Charge0
    Complexity46.5
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count4
    4 Drug and Medication Information
    4.1 Drug Indication

    For use as an over the counter calcium and phosphate supplement, antacid, or a source of calcium and phosphate in toothpaste.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Calcium phosphate reacts with acid in the stomach to raise the pH. In toothpaste it provides a source of calcium and phosphate ions to support remineralization of the teeth. As a supplement it provides a source of calcium and phospate, both of which are important ions in bone homeostasis.

    5.2 Mechanism of Action

    The phosphate ions in calcium phosphate likely react with hydrochloric acid in the stomach to neutralize the pH. In toothpaste and in systemic circulation, calcium phosphate provides a source of calcium and phosphate ions to support remineralization of the teeth and bone homeostasis respectively. The increase in plasma calcium reduces calcium flux from osteocyte activity by reducing the secretion of parathyroid hormone (PTH). Calcium does this by stimulating a G-protein coupled calcium receptor on the surface of parathyroid cells. The reduction in calcium flux increases the amount of calcium deposited in bone resulting in an increase in bone mineral density. The reduction in PTH secretion also reduces the amount of vitamin D metabolized to its active form, calcidiol. Since calcidiol increases the expression of calcium dependent ATPases and transient receptor potential cation channel subfamily V member 6 (TRPV6) both of which are involved in calcium uptake from the gut, a reduction in calcidiol results in less calcium absorption. Additionally, TRPV5, the channel responsible for calcium reabsorption in the kidney, is downregulated when PTH secretion is reduced thus increasing calcium excretion via the kidneys. Another hormone, calitonin, is likely involved in the reduction of bone resorption during periods of high plasma calcium.

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Fillers, Diluents & Binders

    read-more
    read-more

    Topical

    read-more
    read-more

    Taste Masking

    read-more
    read-more

    Coating Systems & Additives

    read-more
    read-more

    Film Formers & Plasticizers

    read-more
    read-more

    Thickeners and Stabilizers

    read-more
    read-more

    Direct Compression

    read-more
    read-more

    Parenteral

    read-more
    read-more

    Granulation

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Solubilizers

    read-more
    read-more

    Co-Processed Excipients

    read-more
    read-more

    Chewable & Orodispersible Aids

    read-more
    read-more

    Lubricants & Glidants

    read-more
    read-more

    Rheology Modifiers

    read-more
    read-more

    Disintegrants & Superdisintegrants

    read-more
    read-more

    Emulsifying Agents

    read-more
    read-more

    API Stability Enhancers

    read-more
    read-more

    Soft Gelatin

    read-more
    read-more

    Surfactant & Foaming Agents

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    DATA COMPILATION #PharmaFlow

    read-more
    read-more

    Market Place

    Do you need sourcing support? Ask us

    ABOUT THIS PAGE

    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search